FI951589A - -fenyyliseriinijohdannaisen stereoselektiivinen valmistusmenetelmä ja sen käyttö taksaanijohdannaisten valmistamiseksi - Google Patents

-fenyyliseriinijohdannaisen stereoselektiivinen valmistusmenetelmä ja sen käyttö taksaanijohdannaisten valmistamiseksi Download PDF

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Publication number
FI951589A
FI951589A FI951589A FI951589A FI951589A FI 951589 A FI951589 A FI 951589A FI 951589 A FI951589 A FI 951589A FI 951589 A FI951589 A FI 951589A FI 951589 A FI951589 A FI 951589A
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FI
Finland
Prior art keywords
formula
pct
preparation
iii
derivative
Prior art date
Application number
FI951589A
Other languages
English (en)
Swedish (sv)
Other versions
FI951589A0 (fi
Inventor
Jean-Noel Denis
Andrew Greene
Alice Kanazawa
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI951589A publication Critical patent/FI951589A/fi
Publication of FI951589A0 publication Critical patent/FI951589A0/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C27/00Processes involving the simultaneous production of more than one class of oxygen-containing compounds
    • C07C27/20Processes involving the simultaneous production of more than one class of oxygen-containing compounds by oxo-reaction
    • C07C27/22Processes involving the simultaneous production of more than one class of oxygen-containing compounds by oxo-reaction with the use of catalysts which are specific for this process
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI951589A 1992-10-05 1995-04-04 -fenyyliseriinijohdannaisen stereoselektiivinen valmistusmenetelmä ja sen käyttö taksaanijohdannaisten valmistamiseksi FI951589A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9211740A FR2696454B1 (fr) 1992-10-05 1992-10-05 Procédé de préparation stéréosélective d'un dérivé de la beta-phénylisosérine et son utilisation pour la préparation de dérivés du Taxane.
PCT/FR1993/000966 WO1994007847A1 (fr) 1992-10-05 1993-10-04 PROCEDE DE PREPARATION STEREOSELECTIVE D'UN DERIVE DE LA β-PHENYLISOSERINE ET SON UTILISATION POUR LA PREPARATION DE DERIVES DU TAXANE

Publications (2)

Publication Number Publication Date
FI951589A true FI951589A (fi) 1995-04-04
FI951589A0 FI951589A0 (fi) 1995-04-04

Family

ID=9434118

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951589A FI951589A0 (fi) 1992-10-05 1995-04-04 -fenyyliseriinijohdannaisen stereoselektiivinen valmistusmenetelmä ja sen käyttö taksaanijohdannaisten valmistamiseksi

Country Status (23)

Country Link
US (2) US5726346A (fi)
EP (1) EP0663901B1 (fi)
JP (1) JPH08502051A (fi)
KR (1) KR100290664B1 (fi)
AT (1) ATE150451T1 (fi)
AU (1) AU682011B2 (fi)
CA (1) CA2146374A1 (fi)
CZ (1) CZ283290B6 (fi)
DE (1) DE69309086T2 (fi)
DK (1) DK0663901T3 (fi)
ES (1) ES2099479T3 (fi)
FI (1) FI951589A0 (fi)
FR (1) FR2696454B1 (fi)
GR (1) GR3022872T3 (fi)
HU (1) HUT73171A (fi)
MX (1) MX9305765A (fi)
NZ (1) NZ256444A (fi)
PL (2) PL176503B1 (fi)
RU (1) RU2109010C1 (fi)
SK (1) SK280576B6 (fi)
TW (1) TW436476B (fi)
WO (1) WO1994007847A1 (fi)
ZA (1) ZA937317B (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6025516A (en) * 1998-10-14 2000-02-15 Chiragene, Inc. Resolution of 2-hydroxy-3-amino-3-phenylpropionamide and its conversion to C-13 sidechain of taxanes
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
US7601847B2 (en) 2004-10-26 2009-10-13 Wyeth Preparation and purification of 4-(indazol-3-yl)phenols
WO2010024762A1 (en) * 2008-08-26 2010-03-04 Organoclick Aktiebolag PREPARATION OF β-PHENYL-ISOSERINE DERIVATIVES
WO2010062239A1 (en) * 2008-11-03 2010-06-03 Cordova Armando A catalytic asymmetric method for the preparation of the paclitaxel (taxol) c-13 side-chain derivatives and its use in the preparation of taxane derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
CA2023645C (fr) * 1989-08-23 2002-03-26 Jean-Noel Denis Procede pour la preparation enantioselective de derives de la phenylisoserine
FR2662441B1 (fr) * 1990-05-22 1992-10-23 Rhone Poulenc Sante Procede de preparation enantioselective de derives de la phenylisoserine.
FR2662440B1 (fr) * 1990-05-22 1992-07-31 Rhone Poulenc Sante Procede de preparation stereoselective de derives de la phenylisoserine.
US5684175A (en) * 1993-02-05 1997-11-04 Napro Biotherapeutics, Inc. C-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process therefor

Also Published As

Publication number Publication date
AU682011B2 (en) 1997-09-18
MX9305765A (es) 1994-05-31
GR3022872T3 (en) 1997-06-30
AU5114993A (en) 1994-04-26
PL173791B1 (pl) 1998-04-30
RU2109010C1 (ru) 1998-04-20
ES2099479T3 (es) 1997-05-16
DK0663901T3 (da) 1997-04-14
KR100290664B1 (ko) 2001-09-17
PL176503B1 (pl) 1999-06-30
SK43795A3 (en) 1995-09-13
DE69309086D1 (de) 1997-04-24
KR950703499A (ko) 1995-09-20
FR2696454A1 (fr) 1994-04-08
FR2696454B1 (fr) 1994-11-25
HUT73171A (en) 1996-06-28
CZ84095A3 (en) 1995-09-13
US5726346A (en) 1998-03-10
TW436476B (en) 2001-05-28
ATE150451T1 (de) 1997-04-15
US6114550A (en) 2000-09-05
WO1994007847A1 (fr) 1994-04-14
EP0663901A1 (fr) 1995-07-26
CZ283290B6 (cs) 1998-02-18
ZA937317B (en) 1994-04-22
DE69309086T2 (de) 1997-09-25
FI951589A0 (fi) 1995-04-04
JPH08502051A (ja) 1996-03-05
CA2146374A1 (fr) 1994-04-14
NZ256444A (en) 1996-06-25
SK280576B6 (sk) 2000-04-10
EP0663901B1 (fr) 1997-03-19
RU95111377A (ru) 1996-12-27
HU9500966D0 (en) 1995-06-28
PL308240A1 (en) 1995-07-24

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