DK0663905T3 - Ny fremgangsmåde dtil forestring af baccatin III og 10-desacetylbaccatin III - Google Patents
Ny fremgangsmåde dtil forestring af baccatin III og 10-desacetylbaccatin IIIInfo
- Publication number
- DK0663905T3 DK0663905T3 DK93921980.4T DK93921980T DK0663905T3 DK 0663905 T3 DK0663905 T3 DK 0663905T3 DK 93921980 T DK93921980 T DK 93921980T DK 0663905 T3 DK0663905 T3 DK 0663905T3
- Authority
- DK
- Denmark
- Prior art keywords
- iii
- radical
- pct
- formula
- image
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9211739A FR2696464B1 (fr) | 1992-10-05 | 1992-10-05 | Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0663905T3 true DK0663905T3 (da) | 1997-02-03 |
Family
ID=9434116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93921980.4T DK0663905T3 (da) | 1992-10-05 | 1993-10-04 | Ny fremgangsmåde dtil forestring af baccatin III og 10-desacetylbaccatin III |
Country Status (24)
| Country | Link |
|---|---|
| US (2) | US5717103A (da) |
| EP (1) | EP0663905B1 (da) |
| JP (1) | JP3064419B2 (da) |
| KR (1) | KR100290663B1 (da) |
| AT (1) | ATE147734T1 (da) |
| AU (1) | AU689446B2 (da) |
| CA (1) | CA2146372C (da) |
| CZ (1) | CZ284818B6 (da) |
| DE (1) | DE69307526T2 (da) |
| DK (1) | DK0663905T3 (da) |
| ES (1) | ES2096328T3 (da) |
| FI (1) | FI115909B (da) |
| FR (1) | FR2696464B1 (da) |
| GR (1) | GR3022286T3 (da) |
| HU (1) | HU225973B1 (da) |
| MX (1) | MX9305764A (da) |
| NO (1) | NO313141B1 (da) |
| NZ (1) | NZ256443A (da) |
| PL (1) | PL178090B1 (da) |
| RU (1) | RU2123493C1 (da) |
| SK (1) | SK281035B6 (da) |
| TW (1) | TW372234B (da) |
| WO (1) | WO1994007876A1 (da) |
| ZA (1) | ZA937316B (da) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6794523B2 (en) | 1991-09-23 | 2004-09-21 | Florida State University | Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them |
| FR2697522B1 (fr) * | 1992-10-30 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
| FR2698361B1 (fr) * | 1992-11-20 | 1995-01-13 | Rhone Poulenc Rorer Sa | Procédé de préparation d'un acide oxazolidine-1,3 carboxylique-5. |
| MX9307777A (es) | 1992-12-15 | 1994-07-29 | Upjohn Co | 7-HALO-Y 7ß, 8ß-METANO-TAXOLES, USO ANTINEOPLASTICO Y COMPOSICIONES FARMACEUTICAS QUE LOS CONTIENEN. |
| PT982302E (pt) * | 1993-06-11 | 2004-07-30 | Upjohn Co | Utilizacao de delta 6,7-taxois antineoplasicos e composicoes farmaceuticas que os contem |
| KR101222904B1 (ko) | 1993-07-19 | 2013-01-17 | 안지오테크 파마슈티칼즈, 인코포레이티드 | 항맥관형성 조성물, 당해 조성물로 피복된 스텐트 및 당해 스텐트의 제조방법 |
| CA2172809A1 (en) * | 1993-11-12 | 1995-05-18 | Richard A. Nugent | Pyrimidine-thioalkyl and alkylether compounds |
| IL127597A (en) * | 1994-01-28 | 2003-07-31 | Upjohn Co | Iso-taxol analogs |
| AU716005B2 (en) | 1995-06-07 | 2000-02-17 | Cook Medical Technologies Llc | Implantable medical device |
| EP0912504B1 (en) * | 1996-05-08 | 2002-09-11 | PHARMACIA & UPJOHN COMPANY | Oxazolidine ester |
| US6150537A (en) * | 1997-12-12 | 2000-11-21 | Emory University | Methods for the esterification of alcohols and compounds useful therefor as potential anticancer agents |
| US20040234472A1 (en) | 2001-04-20 | 2004-11-25 | Jackson John K. | Micellar drug delivery systems for hydrophobic drugs |
| JP4502338B2 (ja) * | 1999-09-17 | 2010-07-14 | 株式会社横浜国際バイオ研究所 | タキソイド化合物の製造法 |
| WO2001024763A2 (en) | 1999-10-01 | 2001-04-12 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
| CA2307393A1 (en) | 2000-05-01 | 2001-11-01 | The University Of British Columbia | Ginsenoside chemotherapy |
| WO2002024179A2 (en) | 2000-09-22 | 2002-03-28 | Bristol-Myers Squibb Company | Method for reducing toxicity of combined chemotherapies |
| US20030054036A1 (en) * | 2001-03-13 | 2003-03-20 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| US20030157170A1 (en) * | 2001-03-13 | 2003-08-21 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
| US7351542B2 (en) | 2002-05-20 | 2008-04-01 | The Regents Of The University Of California | Methods of modulating tubulin deacetylase activity |
| ATE457716T1 (de) | 2002-12-30 | 2010-03-15 | Angiotech Int Ag | Wirkstofffreisetzung von schnell gelierender polymerzusammensetzung |
| US20070172446A1 (en) | 2003-05-16 | 2007-07-26 | Intermune, Inc. | Synthetic chemokine receptor ligands and methods of use thereof |
| US7846940B2 (en) | 2004-03-31 | 2010-12-07 | Cordis Corporation | Solution formulations of sirolimus and its analogs for CAD treatment |
| US8003122B2 (en) | 2004-03-31 | 2011-08-23 | Cordis Corporation | Device for local and/or regional delivery employing liquid formulations of therapeutic agents |
| US7989490B2 (en) | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
| US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
| US20060188508A1 (en) | 2005-02-17 | 2006-08-24 | Cohen Stanley N | Methods and compositions for modulating angiogenesis |
| CA2922029C (en) | 2006-03-22 | 2017-11-28 | Medigene Ag | A combination of a cationic liposomal preparation comprising an antimitotic agent and a non-liposomal preparation comprising an antimitotic agent |
| EP2380606B1 (en) | 2006-06-30 | 2018-03-21 | Cook Medical Technologies LLC | Methods of manufacturing and modifying taxane coatings for implantable medical devices |
| US8409601B2 (en) | 2008-03-31 | 2013-04-02 | Cordis Corporation | Rapamycin coated expandable devices |
| US8420110B2 (en) | 2008-03-31 | 2013-04-16 | Cordis Corporation | Drug coated expandable devices |
| US8273404B2 (en) | 2008-05-19 | 2012-09-25 | Cordis Corporation | Extraction of solvents from drug containing polymer reservoirs |
| EP2859916B1 (en) | 2008-05-22 | 2017-11-29 | Galera Labs, LLC | Combination of an antimitotic agent and a selective superoxide dismutase mimetic in antitumor therapy |
| DK2300489T3 (da) | 2008-06-06 | 2016-02-15 | Neurmedix Inc | Fremgangsmåder til fremstilling af 17-alkynyl-7-hydroxy-steroider og relaterede forbindelser |
| EP2310507A4 (en) | 2008-07-08 | 2013-03-20 | David Gladstone Inst | METHODS AND COMPOSITIONS FOR MODULATING ANGIOGENESIS |
| US8642063B2 (en) | 2008-08-22 | 2014-02-04 | Cook Medical Technologies Llc | Implantable medical device coatings with biodegradable elastomer and releasable taxane agent |
| PL388144A1 (pl) | 2009-05-29 | 2010-12-06 | Przedsiębiorstwo Produkcyjno-Wdrożeniowe Ifotam Spółka Z Ograniczoną Odpowiedzialnością | Solwaty (2R,3S)-3-tert-butoksykarbonylamino-2-hydroksy-3-fenylopropionianu 4-acetoksy-2α-benzoiloksy -5β,20-epoksy-1,7β,10β-trihydroksy-9-okso-taks-11-en-13α-ylu, sposób ich otrzymywania i zastosowanie |
| US20120302954A1 (en) | 2011-05-25 | 2012-11-29 | Zhao Jonathon Z | Expandable devices coated with a paclitaxel composition |
| US20120303115A1 (en) | 2011-05-25 | 2012-11-29 | Dadino Ronald C | Expandable devices coated with a rapamycin composition |
| US9956385B2 (en) | 2012-06-28 | 2018-05-01 | The Spectranetics Corporation | Post-processing of a medical device to control morphology and mechanical properties |
| EP3539563A1 (en) | 2012-07-19 | 2019-09-18 | Redwood Bioscience, Inc. | Antibody specific for cd22 and methods of use thereof |
| WO2014074218A1 (en) | 2012-11-12 | 2014-05-15 | Redwood Bioscience, Inc. | Compounds and methods for producing a conjugate |
| EP3881868B1 (en) | 2013-02-15 | 2023-09-27 | The Regents Of The University Of California | Chimeric antigen receptor and methods of use thereof |
| EP2970124B1 (en) | 2013-03-14 | 2019-05-22 | The Board of Trustees of the Leland Stanford Junior University | Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof |
| JP6745218B2 (ja) | 2013-11-27 | 2020-08-26 | レッドウッド バイオサイエンス， インコーポレイテッド | ヒドラジニル−ピロロ化合物及び複合体を生成するための方法 |
| JP6615769B2 (ja) | 2014-02-19 | 2019-12-04 | アルデア ファーマシューティカルズ インコーポレイテッド | ミトコンドリアアルデヒドデヒドロゲナーゼ２（ａｌｄｈ２）に結合する多環式アミド |
| JP6083815B2 (ja) * | 2014-03-07 | 2017-02-22 | 立川ブラインド工業株式会社 | タッセル |
| AU2016326747A1 (en) | 2015-09-25 | 2018-03-01 | Zy Therapeutics Inc. | Drug formulation based on particulates comprising polysaccharide-vitamin conjugate |
| EP3373977A4 (en) | 2015-11-12 | 2019-07-17 | The Board of Trustees of the Leland Stanford Junior University | CELLULAR PENETRATION-RICH GUANIDINIC OLIGOPHOSPHOTRIESTERS FOR THE DELIVERY OF MEDICATION AND PROBE |
| TWI760319B (zh) | 2015-12-30 | 2022-04-11 | 杏國新藥股份有限公司 | 乳癌治療 |
| US11208632B2 (en) | 2016-04-26 | 2021-12-28 | R.P. Scherer Technologies, Llc | Antibody conjugates and methods of making and using the same |
| EP4019007A1 (en) | 2016-06-01 | 2022-06-29 | Servier IP UK Limited | Formulations of polyalkylene oxide-asparaginase and methods of making and using the same |
| CN110267650A (zh) | 2017-01-05 | 2019-09-20 | 杏国新药股份有限公司 | 胰脏癌治疗 |
| MX2019008503A (es) | 2017-01-18 | 2019-09-13 | F1 Oncology Inc | Receptores de antigenos quimericos contra axl o ror2 y metodos de uso de los mismos. |
| EP3388082A1 (en) | 2017-04-13 | 2018-10-17 | Galera Labs, LLC | Combination cancer immunotherapy with pentaaza macrocyclic ring complex |
| WO2019152661A1 (en) | 2018-01-31 | 2019-08-08 | Galera Labs, Llc | Combination cancer therapy with pentaaza macrocyclic ring complex and platinum-based anticancer agent |
| KR20210009315A (ko) | 2018-04-11 | 2021-01-26 | 오하이오 스테이트 이노베이션 파운데이션 | 안약 전달용 서방형 마이크로 입자를 이용한 방법 및 조성물 |
| WO2020018700A1 (en) | 2018-07-18 | 2020-01-23 | Manzanita Pharmaceuticals, Inc. | Conjugates for delivering an anti-cancer agent to nerve cells, methods of use and methods of making thereof |
| TW202038994A (zh) | 2019-01-14 | 2020-11-01 | 美商醫格耐免疫治療公司 | 重組痘瘡病毒及其使用方法 |
| JP2022520220A (ja) | 2019-02-14 | 2022-03-29 | イグナイト イミュノセラピー インク | 組換えワクシニアウイルスおよびその使用方法 |
| CN113692413A (zh) | 2019-04-02 | 2021-11-23 | 肯乔克蒂生物技术股份有限公司 | 外排泵-癌症抗原多特异性抗体以及与其相关的组合物、试剂、试剂盒和方法 |
| EP4073088A1 (en) | 2019-12-12 | 2022-10-19 | Ignite Immunotherapy, Inc. | Variant oncolytic vaccinia virus and methods of use thereof |
| EP4097134A1 (en) | 2020-01-29 | 2022-12-07 | Kenjockety Biotechnology, Inc. | Anti-mdr1 antibodies and uses thereof |
| EP4161564A1 (en) | 2020-06-04 | 2023-04-12 | Kenjockety Biotechnology, Inc. | Abcg2 efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto |
| CA3182472A1 (en) | 2020-06-04 | 2021-12-09 | Kenjockety Biotechnology, Inc. | Anti-abcg2 antibodies and uses thereof |
| CN116133671A (zh) | 2020-07-14 | 2023-05-16 | 辉瑞公司 | 重组牛痘病毒 |
| CA3193588A1 (en) | 2020-09-02 | 2022-03-10 | Kenjockety Biotechnology, Inc. | Anti-abcc1 antibodies and uses thereof |
| US20240010747A1 (en) | 2020-11-13 | 2024-01-11 | Kenjockety Biotechnology, Inc. | Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof |
| KR20240116829A (ko) | 2021-12-13 | 2024-07-30 | 윌리엄 로버트 아라툰 리빙 트러스트 데이티드 어거스트 29, 2016 | 항-abcb1 항체 |
| WO2023159220A1 (en) | 2022-02-18 | 2023-08-24 | Kenjockety Biotechnology, Inc. | Anti-cd47 antibodies |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US34277A (en) * | 1862-01-28 | Improvement in lamps | ||
| US4942184A (en) * | 1988-03-07 | 1990-07-17 | The United States Of America As Represented By The Department Of Health And Human Services | Water soluble, antineoplastic derivatives of taxol |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| USRE34277E (en) * | 1988-04-06 | 1993-06-08 | Centre National De La Recherche Scientifique | Process for preparing taxol |
| MX9102128A (es) * | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
| FR2696458B1 (fr) * | 1992-10-05 | 1994-11-10 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
| FR2696460B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé de préparation de dérivés du taxane. |
-
1992
- 1992-10-05 FR FR9211739A patent/FR2696464B1/fr not_active Expired - Fee Related
-
1993
- 1993-09-21 MX MX9305764A patent/MX9305764A/es unknown
- 1993-10-01 ZA ZA937316A patent/ZA937316B/xx unknown
- 1993-10-02 TW TW082108116A patent/TW372234B/zh not_active IP Right Cessation
- 1993-10-04 HU HU9500970A patent/HU225973B1/hu unknown
- 1993-10-04 DE DE69307526T patent/DE69307526T2/de not_active Expired - Lifetime
- 1993-10-04 DK DK93921980.4T patent/DK0663905T3/da active
- 1993-10-04 SK SK438-95A patent/SK281035B6/sk not_active IP Right Cessation
- 1993-10-04 US US08/411,691 patent/US5717103A/en not_active Expired - Lifetime
- 1993-10-04 RU RU95110766A patent/RU2123493C1/ru active
- 1993-10-04 KR KR1019950701300A patent/KR100290663B1/ko not_active IP Right Cessation
- 1993-10-04 ES ES93921980T patent/ES2096328T3/es not_active Expired - Lifetime
- 1993-10-04 EP EP93921980A patent/EP0663905B1/fr not_active Expired - Lifetime
- 1993-10-04 AT AT93921980T patent/ATE147734T1/de active
- 1993-10-04 JP JP6508785A patent/JP3064419B2/ja not_active Expired - Lifetime
- 1993-10-04 CA CA002146372A patent/CA2146372C/fr not_active Expired - Lifetime
- 1993-10-04 AU AU51148/93A patent/AU689446B2/en not_active Expired
- 1993-10-04 WO PCT/FR1993/000965 patent/WO1994007876A1/fr active IP Right Grant
- 1993-10-04 PL PL93308239A patent/PL178090B1/pl unknown
- 1993-10-04 NZ NZ256443A patent/NZ256443A/en not_active IP Right Cessation
- 1993-10-04 CZ CZ95839A patent/CZ284818B6/cs not_active IP Right Cessation
-
1995
- 1995-03-29 NO NO19951200A patent/NO313141B1/no not_active IP Right Cessation
- 1995-04-04 FI FI951593A patent/FI115909B/fi not_active IP Right Cessation
-
1997
- 1997-01-16 GR GR960402654T patent/GR3022286T3/el unknown
- 1997-10-31 US US08/962,452 patent/US5977375A/en not_active Expired - Lifetime
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