DE69307526T2 - Neues verfahren zur veresterung von baccatin iii und 10-deacetylbaccatin iii - Google Patents

Neues verfahren zur veresterung von baccatin iii und 10-deacetylbaccatin iii

Info

Publication number
DE69307526T2
DE69307526T2 DE69307526T DE69307526T DE69307526T2 DE 69307526 T2 DE69307526 T2 DE 69307526T2 DE 69307526 T DE69307526 T DE 69307526T DE 69307526 T DE69307526 T DE 69307526T DE 69307526 T2 DE69307526 T2 DE 69307526T2
Authority
DE
Germany
Prior art keywords
iii
radical
pct
formula
image
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69307526T
Other languages
English (en)
Other versions
DE69307526D1 (de
Inventor
Jean-Noel Denis
Andrew Greene
Jean-Manuel Mas
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Rhone Poulenc Rorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer SA filed Critical Rhone Poulenc Rorer SA
Publication of DE69307526D1 publication Critical patent/DE69307526D1/de
Application granted granted Critical
Publication of DE69307526T2 publication Critical patent/DE69307526T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69307526T 1992-10-05 1993-10-04 Neues verfahren zur veresterung von baccatin iii und 10-deacetylbaccatin iii Expired - Lifetime DE69307526T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9211739A FR2696464B1 (fr) 1992-10-05 1992-10-05 Nouveau procédé d'estérification de la baccatine III et de la désacétyl-10 baccatine III.
PCT/FR1993/000965 WO1994007876A1 (fr) 1992-10-05 1993-10-04 Nouveau procede d'esterification de la baccatine iii et de la desacetyl-10 baccatine iii

Publications (2)

Publication Number Publication Date
DE69307526D1 DE69307526D1 (de) 1997-02-27
DE69307526T2 true DE69307526T2 (de) 1997-05-22

Family

ID=9434116

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69307526T Expired - Lifetime DE69307526T2 (de) 1992-10-05 1993-10-04 Neues verfahren zur veresterung von baccatin iii und 10-deacetylbaccatin iii

Country Status (24)

Country Link
US (2) US5717103A (de)
EP (1) EP0663905B1 (de)
JP (1) JP3064419B2 (de)
KR (1) KR100290663B1 (de)
AT (1) ATE147734T1 (de)
AU (1) AU689446B2 (de)
CA (1) CA2146372C (de)
CZ (1) CZ284818B6 (de)
DE (1) DE69307526T2 (de)
DK (1) DK0663905T3 (de)
ES (1) ES2096328T3 (de)
FI (1) FI115909B (de)
FR (1) FR2696464B1 (de)
GR (1) GR3022286T3 (de)
HU (1) HU225973B1 (de)
MX (1) MX9305764A (de)
NO (1) NO313141B1 (de)
NZ (1) NZ256443A (de)
PL (1) PL178090B1 (de)
RU (1) RU2123493C1 (de)
SK (1) SK281035B6 (de)
TW (1) TW372234B (de)
WO (1) WO1994007876A1 (de)
ZA (1) ZA937316B (de)

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NZ276286A (en) * 1993-11-12 2001-06-29 Upjohn Co Substituted pyrimidine thio- or oxy-alkyl derivatives and medicaments
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DE60220519T2 (de) * 2001-04-20 2007-09-27 The University Of British Columbia, Vancouver Mizellares arzneistoffverabreichungssystem für hydrophobe arzneistoffe
US7351542B2 (en) 2002-05-20 2008-04-01 The Regents Of The University Of California Methods of modulating tubulin deacetylase activity
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SI3613439T1 (sl) 2013-02-15 2021-11-30 The Regents Of The University Of California Himerni antigenski receptor in postopki njegove uporabe
CN105358531B (zh) 2013-03-14 2017-11-14 利兰-斯坦福大学初级学院的董事会 线粒体醛脱氢酶‑2调节剂和其使用方法
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US34277A (en) * 1862-01-28 Improvement in lamps
US4942184A (en) * 1988-03-07 1990-07-17 The United States Of America As Represented By The Department Of Health And Human Services Water soluble, antineoplastic derivatives of taxol
USRE34277E (en) * 1988-04-06 1993-06-08 Centre National De La Recherche Scientifique Process for preparing taxol
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
MX9102128A (es) * 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
FR2696458B1 (fr) * 1992-10-05 1994-11-10 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.
FR2696460B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé de préparation de dérivés du taxane.

Also Published As

Publication number Publication date
TW372234B (en) 1999-10-21
MX9305764A (es) 1995-01-31
ZA937316B (en) 1994-04-22
JPH08501787A (ja) 1996-02-27
HUT72616A (en) 1996-05-28
HU9500970D0 (en) 1995-06-28
DK0663905T3 (da) 1997-02-03
FI951593A (fi) 1995-04-04
WO1994007876A1 (fr) 1994-04-14
CZ83995A3 (en) 1995-09-13
CZ284818B6 (cs) 1999-03-17
GR3022286T3 (en) 1997-04-30
RU2123493C1 (ru) 1998-12-20
CA2146372C (fr) 2003-09-09
SK43895A3 (en) 1995-08-09
NZ256443A (en) 1996-07-26
FI115909B (fi) 2005-08-15
FR2696464A1 (fr) 1994-04-08
KR950703545A (ko) 1995-09-20
PL178090B1 (pl) 2000-02-29
ATE147734T1 (de) 1997-02-15
NO313141B1 (no) 2002-08-19
EP0663905B1 (de) 1997-01-15
PL308239A1 (en) 1995-07-24
NO951200D0 (no) 1995-03-29
SK281035B6 (sk) 2000-11-07
CA2146372A1 (fr) 1994-04-14
HU225973B1 (en) 2008-02-28
AU689446B2 (en) 1998-04-02
DE69307526D1 (de) 1997-02-27
EP0663905A1 (de) 1995-07-26
RU95110766A (ru) 1996-12-27
FR2696464B1 (fr) 1994-11-10
AU5114893A (en) 1994-04-26
FI951593A0 (fi) 1995-04-04
ES2096328T3 (es) 1997-03-01
KR100290663B1 (ko) 2001-09-17
US5977375A (en) 1999-11-02
NO951200L (no) 1995-03-29
JP3064419B2 (ja) 2000-07-12
US5717103A (en) 1998-02-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: AVENTIS PHARMA S.A., ANTONY, FR

8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC