FR2424247A2 - Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention - Google Patents

Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention

Info

Publication number
FR2424247A2
FR2424247A2 FR7812452A FR7812452A FR2424247A2 FR 2424247 A2 FR2424247 A2 FR 2424247A2 FR 7812452 A FR7812452 A FR 7812452A FR 7812452 A FR7812452 A FR 7812452A FR 2424247 A2 FR2424247 A2 FR 2424247A2
Authority
FR
France
Prior art keywords
atheroma
substd
aryl
antilipaemic
alkanoic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7812452A
Other languages
English (en)
Other versions
FR2424247B2 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Priority to FR7812452A priority Critical patent/FR2424247A2/fr
Priority to FI783042A priority patent/FI783042A/fi
Priority to ES474002A priority patent/ES474002A1/es
Priority to GR57395A priority patent/GR66480B/el
Priority to SU782672304A priority patent/SU884568A3/ru
Priority to DK444278A priority patent/DK444278A/da
Priority to DE19782843776 priority patent/DE2843776A1/de
Priority to GB7839761A priority patent/GB2007649B/en
Priority to SE7810536A priority patent/SE7810536L/xx
Priority to NL7810163A priority patent/NL7810163A/xx
Priority to AT0726178A priority patent/AT363462B/de
Priority to AU40552/78A priority patent/AU4055278A/en
Priority to PL1978210157A priority patent/PL120454B1/pl
Priority to US05/949,571 priority patent/US4288453A/en
Priority to PT68652A priority patent/PT68652A/fr
Priority to IL7855766A priority patent/IL55766A0/xx
Priority to JP13248478A priority patent/JPS54144328A/ja
Priority to HU78SI1661A priority patent/HU178741B/hu
Priority to IT52191/78A priority patent/IT1158156B/it
Publication of FR2424247A2 publication Critical patent/FR2424247A2/fr
Application granted granted Critical
Publication of FR2424247B2 publication Critical patent/FR2424247B2/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'INVENTION SE RAPPORTE A TITRE DE COMPOSES INDUSTRIELS NOUVEAUX, A DES ACIDES ARYLALCOYLALCANOIQUES ET A LEURS DERIVES REPONDANT A LA FORMULE GENERALE I: (CF DESSIN DANS BOPI) DANS LAQUELLE: Z EST DE L'OXYGENE OU DU SOUFRE; R EST UN RADICAL HYDROCARBONE; AR EST UN RADICAL MONO- OU BICYCLIQUE, HOMO OU HETEROCYCLIQUE EVENTUELLEMENT SUBSTITUE; ET X EST UN HYDROXYLE, UN ALCOXY, UN GROUPE OM, UN RADICAL AMINE OU UN RADICAL HYDROXY AMINE. L'INVENTION S'ETEND AUSSI AUX DIASTEREOISOMERES ERYTHRO ET THREO DES COMPOSES CONFORMES A LA PRESENTE ADDITION. LES COMPOSES CONFORMES A LA PRESENTE ADDITION SONT DOUES DE PROPRIETES PHARMACOLOGIQUES INTERESSANTES QUI LES RENDENT APTES A SERVIR DE PRINCIPE ACTIF DANS DES COMPOSITIONS PHARMACEUTIQUES.
FR7812452A 1977-10-07 1978-04-27 Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention Granted FR2424247A2 (fr)

Priority Applications (19)

Application Number Priority Date Filing Date Title
FR7812452A FR2424247A2 (fr) 1978-04-27 1978-04-27 Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention
ES474002A ES474002A1 (es) 1977-10-07 1978-10-06 Procedimiento de preparacion de nuevos derivados de acidos arilalcanoicos y de sus sales con una base mineral u organi-ca
GR57395A GR66480B (fr) 1977-10-07 1978-10-06
SU782672304A SU884568A3 (ru) 1977-10-07 1978-10-06 Способ получени (арилалкил) алкановых кислот
DK444278A DK444278A (da) 1977-10-07 1978-10-06 Arylalkylalkansyrer og fremgangsmaade til fremstilling heraf
DE19782843776 DE2843776A1 (de) 1977-10-07 1978-10-06 (arylalkyl)-alkansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
FI783042A FI783042A (fi) 1977-10-07 1978-10-06 Foerfarande foer framstaellning av nya derivat av arylalkankarboxylsyror
AT0726178A AT363462B (de) 1977-10-07 1978-10-09 Verfahren zur herstellung von neuen arylalkansaeurederivaten
SE7810536A SE7810536L (sv) 1977-10-07 1978-10-09 Nya arylalkansyraderivat och sett att framstella dessa
NL7810163A NL7810163A (nl) 1977-10-07 1978-10-09 Arylalkylalkaancarbonzuren, geneesmiddel met als werk- zaam bestanddeel alkaancarbonzuur en werkwijze voor de bereiding van de arylalkylalkaancarbonzuren.
GB7839761A GB2007649B (en) 1977-10-07 1978-10-09 Derivatives of arylalcanoic acid and processes for making them
AU40552/78A AU4055278A (en) 1977-10-07 1978-10-09 Novel derivatives of arylalcanoic acids and processes for making them
PL1978210157A PL120454B1 (en) 1977-10-07 1978-10-09 Process for preparing novel derivatives of arylalkanocarboxylic acidsvykh kislot
US05/949,571 US4288453A (en) 1977-10-07 1978-10-10 Derivatives of arylalkanoic acids, compositions and use
PT68652A PT68652A (fr) 1978-04-27 1978-10-13 Procede d'obtention de nouveaux derives d'acides arylalcanoiques
IL7855766A IL55766A0 (en) 1978-04-27 1978-10-19 Novel arylalkanoic acids and derivatives thereof,their production and pharmaceutical compositions containing them
JP13248478A JPS54144328A (en) 1978-04-27 1978-10-27 Novel derivative of arylalkanoic acid
HU78SI1661A HU178741B (en) 1978-04-27 1978-11-08 Process for producing new arylalkanoic acid derivatives
IT52191/78A IT1158156B (it) 1978-04-27 1978-12-05 Procedimento per la preparazione di derivati di acidi arilalcanoici e relative composizioni farmaceutiche

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7812452A FR2424247A2 (fr) 1978-04-27 1978-04-27 Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention

Publications (2)

Publication Number Publication Date
FR2424247A2 true FR2424247A2 (fr) 1979-11-23
FR2424247B2 FR2424247B2 (fr) 1980-10-10

Family

ID=9207642

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7812452A Granted FR2424247A2 (fr) 1977-10-07 1978-04-27 Nouveaux derives d'acides arylalcanoiques a action hypolipemiante et leurs procedes d'obtention

Country Status (6)

Country Link
JP (1) JPS54144328A (fr)
FR (1) FR2424247A2 (fr)
HU (1) HU178741B (fr)
IL (1) IL55766A0 (fr)
IT (1) IT1158156B (fr)
PT (1) PT68652A (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2472560A2 (fr) * 1979-11-30 1981-07-03 Science Union & Cie Nouveaux derives d'acides alcanoiques, leur procede d'obtention et leur utilisation therapeutique

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR93175E (fr) * 1964-03-20 1969-02-21 Merck & Co Inc Nouveaux acides alkanoiques a substituant aryle et procédés pour leur préparation.
FR1573841A (fr) * 1966-10-03 1969-07-11
US3742043A (en) * 1972-04-24 1973-06-26 Dow Chemical Co 2-(alpha,alpha-bis(trifluoromethyl)benzyloxy) acetic acid and esters thereof
FR2296405A1 (fr) * 1974-12-30 1976-07-30 Synthelabo Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment
FR2325362A2 (fr) * 1975-09-26 1977-04-22 Synthelabo Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment
FR2351945A1 (fr) * 1976-05-21 1977-12-16 Ici Ltd Nouveaux derives aromatiques de l'acide acetique, leur procede de preparation et medicament les contenant

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR93175E (fr) * 1964-03-20 1969-02-21 Merck & Co Inc Nouveaux acides alkanoiques a substituant aryle et procédés pour leur préparation.
FR1573841A (fr) * 1966-10-03 1969-07-11
US3742043A (en) * 1972-04-24 1973-06-26 Dow Chemical Co 2-(alpha,alpha-bis(trifluoromethyl)benzyloxy) acetic acid and esters thereof
FR2296405A1 (fr) * 1974-12-30 1976-07-30 Synthelabo Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment
FR2325362A2 (fr) * 1975-09-26 1977-04-22 Synthelabo Nouveaux derives de l'acide phenyl-acetique, leur preparation et les medicaments qui les renferment
FR2351945A1 (fr) * 1976-05-21 1977-12-16 Ici Ltd Nouveaux derives aromatiques de l'acide acetique, leur procede de preparation et medicament les contenant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2472560A2 (fr) * 1979-11-30 1981-07-03 Science Union & Cie Nouveaux derives d'acides alcanoiques, leur procede d'obtention et leur utilisation therapeutique

Also Published As

Publication number Publication date
PT68652A (fr) 1978-11-01
IT1158156B (it) 1987-02-18
IL55766A0 (en) 1978-12-17
JPS54144328A (en) 1979-11-10
HU178741B (en) 1982-06-28
IT7852191A0 (it) 1978-12-05
FR2424247B2 (fr) 1980-10-10

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