KR840000763B1 - 2-아미노-3-벤조일-페닐아세트아미드의 제조방법 - Google Patents

2-아미노-3-벤조일-페닐아세트아미드의 제조방법 Download PDF

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Publication number
KR840000763B1
KR840000763B1 KR1019800003740A KR800003740A KR840000763B1 KR 840000763 B1 KR840000763 B1 KR 840000763B1 KR 1019800003740 A KR1019800003740 A KR 1019800003740A KR 800003740 A KR800003740 A KR 800003740A KR 840000763 B1 KR840000763 B1 KR 840000763B1
Authority
KR
South Korea
Prior art keywords
amino
solution
phenylacetamide
benzoyl
added
Prior art date
Application number
KR1019800003740A
Other languages
English (en)
Korean (ko)
Other versions
KR830004210A (ko
Inventor
쥬니어 제임스 로버트 쉥클린
알렌 샴블리 드와이트
알란 월쉬 데비드
Original Assignee
에이. 에이치. 로빈스 캄파니 인코포레이티드
알. 피. 울프
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 에이. 에이치. 로빈스 캄파니 인코포레이티드, 알. 피. 울프 filed Critical 에이. 에이치. 로빈스 캄파니 인코포레이티드
Publication of KR830004210A publication Critical patent/KR830004210A/ko
Application granted granted Critical
Publication of KR840000763B1 publication Critical patent/KR840000763B1/ko

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
KR1019800003740A 1979-09-26 1980-09-25 2-아미노-3-벤조일-페닐아세트아미드의 제조방법 KR840000763B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7886079A 1979-09-26 1979-09-26
US078,860 1979-09-26
US78860 1979-09-26

Publications (2)

Publication Number Publication Date
KR830004210A KR830004210A (ko) 1983-07-06
KR840000763B1 true KR840000763B1 (ko) 1984-06-08

Family

ID=22146633

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019800003740A KR840000763B1 (ko) 1979-09-26 1980-09-25 2-아미노-3-벤조일-페닐아세트아미드의 제조방법

Country Status (36)

Country Link
JP (1) JPS5657751A (xx)
KR (1) KR840000763B1 (xx)
AT (1) AT374170B (xx)
AU (1) AU532359B2 (xx)
BE (1) BE885393A (xx)
BR (1) BR8006042A (xx)
CA (1) CA1128512A (xx)
CH (1) CH646138A5 (xx)
CS (1) CS227012B2 (xx)
DE (1) DE3035688A1 (xx)
DK (1) DK154136C (xx)
EG (1) EG15020A (xx)
ES (2) ES495329A0 (xx)
FI (1) FI72967C (xx)
FR (1) FR2465710A1 (xx)
GB (1) GB2059963B (xx)
GR (1) GR70049B (xx)
HK (1) HK59383A (xx)
HU (1) HU183215B (xx)
IE (1) IE50268B1 (xx)
IL (1) IL60999A (xx)
IN (3) IN151313B (xx)
IT (1) IT1133823B (xx)
KE (1) KE3307A (xx)
LU (1) LU82797A1 (xx)
MX (1) MX7159E (xx)
NL (1) NL8005346A (xx)
NO (1) NO152128C (xx)
NZ (1) NZ195061A (xx)
PH (1) PH22628A (xx)
PL (1) PL128998B1 (xx)
PT (1) PT71839B (xx)
SE (1) SE448626B (xx)
SG (1) SG42983G (xx)
YU (3) YU41734B (xx)
ZA (1) ZA805476B (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them
US6066671A (en) * 1997-12-19 2000-05-23 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides
US6646001B2 (en) 1997-12-19 2003-11-11 Alcon Manufacturing, Ltd. Use of non-steroidal anti-inflammatory agents in combination with prostaglandin FP receptor agonists to treat glaucoma and ocular hypertension
GB9727523D0 (en) * 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
AR030345A1 (es) * 2000-08-14 2003-08-20 Alcon Inc Metodo de tratamiento de desordenes relacionados con angiogenesis
PT1423168E (pt) 2001-09-03 2006-05-31 Newron Pharm Spa Composicao farmaceutica que compreende gabapentina ou um seu analogo e uma x-aminoamida e a sua utilizacao como analgesico
EP1438956A1 (en) 2003-01-16 2004-07-21 Newron Pharmaceuticals S.p.A. Alpha-aminoamide derivatives useful as antimigraine agents
CZ2009367A3 (cs) * 2009-06-08 2010-06-16 Farmak, A.S. Postup prípravy 2-amino-3-benzoylfenylacetamidu (nepafenacu) s minimem vedlejších produktu
CN112794809B (zh) * 2019-11-14 2023-12-29 南京济群医药科技股份有限公司 一种高纯度奈帕芬胺中间体的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1226344A (xx) * 1967-07-31 1971-03-24
SE400966B (sv) * 1975-08-13 1978-04-17 Robins Co Inc A H Forfarande for framstellning av 2-amino-3-(eller 5-)bensoyl-fenylettiksyror
IL61945A (en) * 1980-02-19 1984-09-30 Robins Co Inc A H 2-amino-3-(hydroxy(phenyl)methyl)phenylacetic acids,esters and amides and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
GR70049B (xx) 1982-07-26
KE3307A (en) 1983-08-19
DK154136B (da) 1988-10-17
ES8200329A1 (es) 1981-10-16
HU183215B (en) 1984-04-28
DK405780A (da) 1981-03-27
FR2465710B1 (xx) 1984-10-12
IL60999A (en) 1984-05-31
YU43306B (en) 1989-06-30
IE801946L (en) 1981-03-26
YU73183A (en) 1983-12-31
JPS5657751A (en) 1981-05-20
NZ195061A (en) 1984-04-27
JPH0141616B2 (xx) 1989-09-06
LU82797A1 (fr) 1982-05-10
BR8006042A (pt) 1981-04-07
ES8204715A1 (es) 1982-05-01
FI72967B (fi) 1987-04-30
IN151313B (xx) 1983-03-26
NL8005346A (nl) 1981-03-30
CH646138A5 (fr) 1984-11-15
NO152128B (no) 1985-04-29
FI72967C (fi) 1987-08-10
IL60999A0 (en) 1980-11-30
AU6211680A (en) 1981-04-02
YU41734B (en) 1987-12-31
ES503019A0 (es) 1982-05-01
HK59383A (en) 1983-12-02
AU532359B2 (en) 1983-09-29
NO152128C (no) 1985-08-07
PL128998B1 (en) 1984-03-31
GB2059963A (en) 1981-04-29
YU245080A (en) 1983-09-30
IT1133823B (it) 1986-07-24
FR2465710A1 (fr) 1981-03-27
EG15020A (en) 1985-03-31
YU73083A (en) 1983-12-31
IE50268B1 (en) 1986-03-19
DE3035688A1 (de) 1981-04-16
DK154136C (da) 1989-03-06
GB2059963B (en) 1983-04-20
SE8006668L (sv) 1981-03-27
YU43305B (en) 1989-06-30
MX7159E (es) 1987-12-02
ES495329A0 (es) 1981-10-16
FI803002A (fi) 1981-03-27
SG42983G (en) 1985-01-11
IN156254B (xx) 1985-06-08
IT8024948A0 (it) 1980-09-26
AT374170B (de) 1984-03-26
KR830004210A (ko) 1983-07-06
NO802834L (no) 1981-03-27
BE885393A (fr) 1981-01-16
PH22628A (en) 1988-10-28
PL226919A1 (xx) 1982-02-01
IN156255B (xx) 1985-06-08
PT71839B (en) 1981-06-25
PT71839A (en) 1980-10-01
DE3035688C2 (xx) 1990-05-17
CS227012B2 (en) 1984-04-16
ATA474580A (de) 1983-08-15
CA1128512A (en) 1982-07-27
SE448626B (sv) 1987-03-09
ZA805476B (en) 1981-11-25

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