KR20220025231A - 비전이성 거세 저항성 전립선암 치료용 항안드로겐 - Google Patents
비전이성 거세 저항성 전립선암 치료용 항안드로겐 Download PDFInfo
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- KR20220025231A KR20220025231A KR1020227004751A KR20227004751A KR20220025231A KR 20220025231 A KR20220025231 A KR 20220025231A KR 1020227004751 A KR1020227004751 A KR 1020227004751A KR 20227004751 A KR20227004751 A KR 20227004751A KR 20220025231 A KR20220025231 A KR 20220025231A
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
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- A—HUMAN NECESSITIES
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- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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- Diabetes (AREA)
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- Gastroenterology & Hepatology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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- Physiology (AREA)
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Applications Claiming Priority (4)
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| US61/705,900 | 2012-09-26 | ||
| PCT/US2013/061197 WO2014052237A1 (en) | 2012-09-26 | 2013-09-23 | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
| KR1020217002756A KR20210013342A (ko) | 2012-09-26 | 2013-09-23 | 비전이성 거세 저항성 전립선암 치료용 항안드로겐 |
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| KR1020217002756A Division KR20210013342A (ko) | 2012-09-26 | 2013-09-23 | 비전이성 거세 저항성 전립선암 치료용 항안드로겐 |
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| KR1020157010627A Active KR102210825B1 (ko) | 2012-09-26 | 2013-09-23 | 비전이성 거세 저항성 전립선암 치료용 항안드로겐 |
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| KR1020157010627A Active KR102210825B1 (ko) | 2012-09-26 | 2013-09-23 | 비전이성 거세 저항성 전립선암 치료용 항안드로겐 |
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| AU2011218173C1 (en) | 2010-02-16 | 2015-04-16 | Aragon Pharmaceuticals, Inc. | Androgen receptor modulators and uses thereof |
| AP2014007657A0 (en) | 2011-12-16 | 2014-05-31 | Olema Pharmaceuticals Inc | Novel benzopyran compounds, compositions and uses thereof |
| UA117663C2 (uk) | 2012-09-26 | 2018-09-10 | Арагон Фармасьютікалз, Інк. | Антиандроген для лікування неметастатичного кастраційно-резистентного раку передміхурової залози |
| JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
| LT3226843T (lt) * | 2014-12-05 | 2021-08-10 | Aragon Pharmaceuticals, Inc. | Priešvėžinės kompozicijos |
| PT3226842T (pt) * | 2014-12-05 | 2020-12-23 | Aragon Pharmaceuticals Inc | Composições anticancerígenas |
| MA41107B1 (fr) * | 2014-12-05 | 2025-01-31 | Aragon Pharmaceuticals, Inc. | Compositions anti-cancéreuses |
| KR101718226B1 (ko) | 2015-08-05 | 2017-03-20 | 울산대학교 산학협력단 | 사쿠라소사포닌 화합물을 유효성분으로 포함하는 안드로겐 수용체 관련 질환의 예방 또는 치료용 조성물 |
| TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
| RS66574B1 (sr) * | 2016-07-29 | 2025-03-31 | Janssen Pharmaceutica Nv | Niraparib za upotrebu u postupku lečenja raka prostate |
| US10702508B2 (en) * | 2017-10-16 | 2020-07-07 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
| PH12021551657A1 (en) | 2019-01-30 | 2022-05-02 | Aragon Pharmaceuticals Inc | Anti-androgens for the treatment of metastatic castration-sensitive prostate cancer |
| JP2023500935A (ja) * | 2019-11-04 | 2023-01-11 | アラゴン ファーマシューティカルズ，インコーポレイテッド | 重度の肝障害を有する対象における非転移性去勢抵抗性前立腺癌の治療のためのアンドロゲン受容体阻害剤 |
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