EA201890598A3 - Антиандрогены для лечения неметастатического кастрационно-резистентного рака простаты - Google Patents

Антиандрогены для лечения неметастатического кастрационно-резистентного рака простаты

Info

Publication number
EA201890598A3
EA201890598A3 EA201890598A EA201890598A EA201890598A3 EA 201890598 A3 EA201890598 A3 EA 201890598A3 EA 201890598 A EA201890598 A EA 201890598A EA 201890598 A EA201890598 A EA 201890598A EA 201890598 A3 EA201890598 A3 EA 201890598A3
Authority
EA
Eurasian Patent Office
Prior art keywords
antiandrogens
treatment
prostate
metastatic castration
resistant cancer
Prior art date
Application number
EA201890598A
Other languages
English (en)
Other versions
EA201890598A2 (ru
EA037806B1 (ru
Inventor
Исан Чэнь
Original Assignee
Арагон Фармасьютикалз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49293921&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201890598(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Арагон Фармасьютикалз, Инк. filed Critical Арагон Фармасьютикалз, Инк.
Publication of EA201890598A2 publication Critical patent/EA201890598A2/ru
Publication of EA201890598A3 publication Critical patent/EA201890598A3/ru
Publication of EA037806B1 publication Critical patent/EA037806B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

В заявке описаны антиандрогены для применения в лечении неметастатического кастрационно-резистентного рака простаты.
EA201890598A 2012-09-26 2013-09-23 Способ лечения неметастатического кастрационно-резистентного рака простаты EA037806B1 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261705900P 2012-09-26 2012-09-26

Publications (3)

Publication Number Publication Date
EA201890598A2 EA201890598A2 (ru) 2018-07-31
EA201890598A3 true EA201890598A3 (ru) 2019-03-29
EA037806B1 EA037806B1 (ru) 2021-05-24

Family

ID=49293921

Family Applications (3)

Application Number Title Priority Date Filing Date
EA201890598A EA037806B1 (ru) 2012-09-26 2013-09-23 Способ лечения неметастатического кастрационно-резистентного рака простаты
EA202190820A EA202190820A1 (ru) 2012-09-26 2013-09-23 Антиандрогены для лечения неметастатического кастрационно-резистентного рака простаты
EA201590650A EA030128B1 (ru) 2012-09-26 2013-09-23 Способ лечения неметастатического кастрационно-резистентного рака простаты

Family Applications After (2)

Application Number Title Priority Date Filing Date
EA202190820A EA202190820A1 (ru) 2012-09-26 2013-09-23 Антиандрогены для лечения неметастатического кастрационно-резистентного рака простаты
EA201590650A EA030128B1 (ru) 2012-09-26 2013-09-23 Способ лечения неметастатического кастрационно-резистентного рака простаты

Country Status (35)

Country Link
US (7) US9884054B2 (ru)
EP (3) EP3777845A1 (ru)
JP (4) JP6351597B2 (ru)
KR (3) KR102210825B1 (ru)
CN (4) CN109999036A (ru)
AU (3) AU2013323861C1 (ru)
BR (1) BR112015006705A8 (ru)
CA (1) CA2885415C (ru)
CL (1) CL2015000715A1 (ru)
CR (1) CR20150140A (ru)
CY (1) CY1123716T1 (ru)
DK (1) DK3305285T3 (ru)
EA (3) EA037806B1 (ru)
EC (1) ECSP15011764A (ru)
ES (1) ES2836424T3 (ru)
GT (1) GT201500071A (ru)
HK (2) HK1252867A1 (ru)
HR (1) HRP20201721T1 (ru)
HU (1) HUE051211T2 (ru)
IL (3) IL312316A (ru)
IN (1) IN2015DN02387A (ru)
LT (1) LT3305285T (ru)
MX (2) MX371020B (ru)
MY (1) MY180834A (ru)
NI (1) NI201500042A (ru)
NZ (3) NZ745682A (ru)
PE (1) PE20150765A1 (ru)
PH (3) PH12015500615A1 (ru)
PT (1) PT3305285T (ru)
RS (1) RS60976B1 (ru)
SG (3) SG10201912719TA (ru)
SI (1) SI3305285T1 (ru)
UA (2) UA117663C2 (ru)
WO (1) WO2014052237A1 (ru)
ZA (1) ZA201808499B (ru)

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SI3124481T1 (en) 2010-02-16 2018-06-29 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and their use
BR112014014767A2 (pt) 2011-12-16 2017-06-13 Olema Pharmaceuticals Inc novos compostos de benzopirano, composições e usos dos mesmos
SI3305285T1 (sl) 2012-09-26 2021-03-31 Aragon Pharmaceuticals, Inc. Anti-androgeni za zdravljenje proti kastraciji odpornega ne-metastatskega raka
JOP20200097A1 (ar) * 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
MA41107A (fr) * 2014-12-05 2017-10-10 Aragon Pharmaceuticals Inc Compositions anti-cancéreuses
MX2017007201A (es) * 2014-12-05 2018-01-30 Aragon Pharmaceuticals Inc Composiciones anticancerigenas.
DK3226843T3 (da) * 2014-12-05 2021-08-16 Aragon Pharmaceuticals Inc Anticancersammensætninger
KR101718226B1 (ko) 2015-08-05 2017-03-20 울산대학교 산학협력단 사쿠라소사포닌 화합물을 유효성분으로 포함하는 안드로겐 수용체 관련 질환의 예방 또는 치료용 조성물
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
JP7201694B2 (ja) 2017-10-16 2023-01-10 アラゴン ファーマシューティカルズ，インコーポレイテッド 非転移性去勢抵抗性前立腺癌の治療のための抗アンドロゲン剤
AU2020215176A1 (en) * 2019-01-30 2021-08-05 Aragon Pharmaceuticals, Inc. Anti-androgens for the treatment of metastatic castration-sensitive prostate cancer
US11723898B2 (en) * 2019-11-04 2023-08-15 Aragon Pharmaceuticals, Inc. Androgen receptor inhibitors for the treatment of non-metastatic castration-resistant prostate cancer in subjects with severe hepatic impairment

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