DE602004031881D1 - Verfahren und materialien zur beurteilung von prostatakrebstherapien - Google Patents
Verfahren und materialien zur beurteilung von prostatakrebstherapienInfo
- Publication number
- DE602004031881D1 DE602004031881D1 DE602004031881T DE602004031881T DE602004031881D1 DE 602004031881 D1 DE602004031881 D1 DE 602004031881D1 DE 602004031881 T DE602004031881 T DE 602004031881T DE 602004031881 T DE602004031881 T DE 602004031881T DE 602004031881 D1 DE602004031881 D1 DE 602004031881D1
- Authority
- DE
- Germany
- Prior art keywords
- androgens
- materials
- prostate acid
- acid therapies
- assessing prostate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57434—Specifically defined cancers of prostate
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/723—Steroid/thyroid hormone superfamily, e.g. GR, EcR, androgen receptor, oestrogen receptor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Hospice & Palliative Care (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53109103P | 2003-12-19 | 2003-12-19 | |
PCT/US2004/042221 WO2005060661A2 (en) | 2003-12-19 | 2004-12-16 | Methods and materials for assessing prostate cancer therapies |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004031881D1 true DE602004031881D1 (de) | 2011-04-28 |
Family
ID=34710203
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004031881T Active DE602004031881D1 (de) | 2003-12-19 | 2004-12-16 | Verfahren und materialien zur beurteilung von prostatakrebstherapien |
Country Status (9)
Country | Link |
---|---|
US (1) | US8034548B2 (de) |
EP (2) | EP2299266A1 (de) |
JP (1) | JP2007514442A (de) |
AT (1) | ATE502298T1 (de) |
AU (1) | AU2004305075A1 (de) |
CA (1) | CA2550447A1 (de) |
DE (1) | DE602004031881D1 (de) |
NZ (1) | NZ548209A (de) |
WO (1) | WO2005060661A2 (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7718684B2 (en) | 2004-02-24 | 2010-05-18 | The Regents Of The University Of California | Methods and materials for assessing prostate cancer therapies and compounds |
US7709517B2 (en) | 2005-05-13 | 2010-05-04 | The Regents Of The University Of California | Diarylhydantoin compounds |
CN105902559A (zh) | 2005-08-01 | 2016-08-31 | 俄亥俄州立大学研究基金会 | 用于乳腺癌的诊断、预后和治疗的基于MicroRNA的方法和组合物 |
CN101296702B (zh) | 2005-09-12 | 2012-11-28 | 俄亥俄州立大学研究基金会 | 用于诊断或治疗bcl2相关癌症的组合物和方法 |
EP2586455B1 (de) | 2006-01-05 | 2014-06-25 | The Ohio State University Research Foundation | Anomalien bei Mikro-RNA-Expressionen in endokrinen und azinösen Pankreastumoren |
CN103993082B (zh) | 2006-01-05 | 2017-01-11 | 俄亥俄州立大学研究基金会 | 用于肺癌的诊断、预后和治疗的基于微小rna 的方法和组合物 |
EP2468890B1 (de) | 2006-01-05 | 2014-03-19 | The Ohio State University Research Foundation | Verfahren und Zusammensetzungen auf Mikro-RNA-Basis zur Diagnose und Behandlung von festen Krebsen der Lunge oder Brust |
EP2369013A1 (de) | 2006-03-20 | 2011-09-28 | The Ohio State University Research Foundation | Mikro-RNA-Fingerabdrücke während humaner Megakaryozytopoiese |
DK2656841T3 (en) | 2006-03-27 | 2016-12-05 | Univ California | Androgen receptor MODULATOR FOR THE TREATMENT OF PROSTATE CANCER AND androgen receptor-ASSOCIATED DISEASES |
RU2449993C2 (ru) | 2006-03-29 | 2012-05-10 | Те Риджентс Оф Те Юниверсити Оф Калифорния | Диарилтиогидантоиновые соединения |
EP2455492B1 (de) | 2006-07-13 | 2013-11-20 | The Ohio State University Research Foundation | Verfahren und Zusammensetzungen auf Mikro-RNA-Basis zur Diagnose und Behandlung von Krankheiten im Zusammenhang mit dem Dickdarm |
ES2374446T3 (es) | 2006-09-19 | 2012-02-16 | The Ohio State University Research Foundation | Expresión de tcl1 en la leucemia linfocítica crónica (llc) regulada por mir-29 y mir-181. |
WO2008054828A2 (en) | 2006-11-01 | 2008-05-08 | The Ohio State University Research Foundation | Microrna expression signature for predicting survival and metastases in hepatocellular carcinoma |
EP2109687B1 (de) | 2007-01-31 | 2014-06-04 | The Ohio State University Research Foundation | Micro-rna-basierte verfahren zur behandlung von akuter myeloischer leukämie (aml) |
WO2008112283A2 (en) * | 2007-03-12 | 2008-09-18 | Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Microrna profiling of androgen responsiveness for predicting the appropriate prostate cancer treatment |
AU2008262252B2 (en) | 2007-06-08 | 2013-09-12 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Methods for determining hepatocellular carcinoma subtype and detecting hepatic cancer stem cells |
US8053186B2 (en) | 2007-06-15 | 2011-11-08 | The Ohio State University Research Foundation | Oncogenic ALL-1 fusion proteins for targeting Drosha-mediated microRNA processing |
JP2010535782A (ja) | 2007-07-31 | 2010-11-25 | ズィ、オハイオウ、ステイト、ユーニヴァーサティ、リサーチ、ファウンデイシャン | Dnmt3a及びdnmt3bを標的にすることによるメチル化を元に戻す方法 |
EP2173908B1 (de) | 2007-08-03 | 2016-01-06 | The Ohio State University Research Foundation | Ultrakonservierte bereiche zur kodierung von ncrnas |
CA2696887C (en) | 2007-08-22 | 2016-06-28 | The Ohio State University Research Foundation | Methods and compositions for inducing deregulation of epha7 and erk phosphorylation in human acute leukemias |
AU2008316577B2 (en) | 2007-10-26 | 2014-04-10 | The Ohio State University Research Foundation | Methods for identifying fragile histidine triad (FHIT) interaction and uses thereof |
CA2966280A1 (en) * | 2007-10-26 | 2009-04-30 | The Regents Of The University Of California | Diarylhydantoin compounds |
US20110054009A1 (en) * | 2008-02-28 | 2011-03-03 | The Ohio State University Research Foundation | MicroRNA-Based Methods and Compositions for the Diagnosis, Prognosis and Treatment of Prostate Related Disorders |
JP5745401B2 (ja) | 2008-06-11 | 2015-07-08 | アメリカ合衆国 | 肝細胞癌についての予測マーカーとしてのMiR−26ファミリーの使用および療法に対する反応性 |
AU2010321555B2 (en) | 2009-11-23 | 2015-10-15 | The Ohio State University | Materials and methods useful for affecting tumor cell growth, migration and invasion |
WO2011103202A2 (en) | 2010-02-16 | 2011-08-25 | Aragon Pharmaceuticals, Inc. | Androgen receptor modulators and uses thereof |
WO2012065051A1 (en) | 2010-11-12 | 2012-05-18 | Enzon Pharmaceuticals, Inc. | Compositions and methods for treating androgen receptor dependent disorders including cancers |
ES2606146T3 (es) | 2010-11-12 | 2017-03-22 | The Ohio State University Research Foundation | Métodos relacionados con microARN-21 y reparación de desapareamiento en cáncer colorrectal |
CN103313706A (zh) | 2010-11-15 | 2013-09-18 | 俄亥俄州立大学研究基金会 | 控制释放粘膜粘合系统 |
EP2683387A4 (de) | 2011-03-07 | 2014-09-03 | Univ Ohio State | Durch mikro-rna-155 (mir-155) induzierte mutatorgenaktivität gegen entzündungen und krebs |
WO2013056217A1 (en) | 2011-10-14 | 2013-04-18 | The Ohio State University | Methods and materials related to ovarian cancer |
JP2015501843A (ja) | 2011-12-13 | 2015-01-19 | オハイオ・ステイト・イノベーション・ファウンデーション | miR−21およびmiR−29a、エキソソーム阻害、およびがん転移に関する方法および組成物 |
JP2015511121A (ja) | 2012-01-20 | 2015-04-16 | ジ・オハイオ・ステート・ユニバーシティ | 浸潤性および予後に関する乳がんバイオマーカーシグネチャー |
KR20220025231A (ko) | 2012-09-26 | 2022-03-03 | 아라곤 파마슈티컬스, 인코포레이티드 | 비전이성 거세 저항성 전립선암 치료용 항안드로겐 |
EP2912194B1 (de) * | 2012-10-26 | 2019-05-08 | Memorial Sloan-Kettering Cancer Center | Androgenrezeptorvarianten und verfahren zur herstellung und verwendung |
JOP20200097A1 (ar) | 2013-01-15 | 2017-06-16 | Aragon Pharmaceuticals Inc | معدل مستقبل أندروجين واستخداماته |
TWI726969B (zh) | 2016-01-11 | 2021-05-11 | 比利時商健生藥品公司 | 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物 |
KR20200070334A (ko) | 2017-10-16 | 2020-06-17 | 아라곤 파마슈티컬스, 인코포레이티드 | 비-전이성 거세-저항성 전립선암의 치료를 위한 항-안드로겐 |
KR102417496B1 (ko) * | 2019-11-29 | 2022-07-06 | (주)수파드엘릭사 | 안드로겐 수용체의 활성을 억제하는 폡타이드 및 이를 이용하는 화장료 조성물 |
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WO2005059109A2 (en) * | 2003-12-15 | 2005-06-30 | The Regents Of The University Of California | Molecular signature of the pten tumor suppressor |
US7718684B2 (en) | 2004-02-24 | 2010-05-18 | The Regents Of The University Of California | Methods and materials for assessing prostate cancer therapies and compounds |
AU2005222627A1 (en) | 2004-03-15 | 2005-09-29 | Ptc Therapeutics, Inc. | Tetra-cyclic carboline derivatives for inhibiting angiogenesis |
EP1621539A1 (de) | 2004-07-27 | 2006-02-01 | Aventis Pharma S.A. | Heterocyclische-substituirte cyclische Harnstoffderivate, Verfaren zu ihrer Herstellung, und ihre pharmaceutische Verwendung als Kinase Inhibitoren |
US7803826B2 (en) | 2004-08-03 | 2010-09-28 | Chugai Seiyaku Kabushiki Kaisha | Imidazolidine derivatives |
CA2579886A1 (en) | 2004-09-09 | 2006-03-16 | Chugai Seiyaku Kabushiki Kaisha | Novel imidazolidine derivative and use thereof |
DK2444085T3 (en) | 2005-05-13 | 2015-04-27 | Univ California | Diarylhydantoinforbindelser as androgenreceptorantagonister for treating cancer |
DK2656841T3 (en) | 2006-03-27 | 2016-12-05 | Univ California | Androgen receptor MODULATOR FOR THE TREATMENT OF PROSTATE CANCER AND androgen receptor-ASSOCIATED DISEASES |
RU2449993C2 (ru) | 2006-03-29 | 2012-05-10 | Те Риджентс Оф Те Юниверсити Оф Калифорния | Диарилтиогидантоиновые соединения |
US8461343B2 (en) | 2007-03-27 | 2013-06-11 | Sloan-Kettering Institute For Cancer Research | Synthesis of thiohydantoins |
-
2004
- 2004-12-16 EP EP10011639A patent/EP2299266A1/de not_active Withdrawn
- 2004-12-16 AU AU2004305075A patent/AU2004305075A1/en not_active Abandoned
- 2004-12-16 JP JP2006545417A patent/JP2007514442A/ja active Pending
- 2004-12-16 EP EP04814409A patent/EP1709193B1/de not_active Not-in-force
- 2004-12-16 WO PCT/US2004/042221 patent/WO2005060661A2/en active Application Filing
- 2004-12-16 DE DE602004031881T patent/DE602004031881D1/de active Active
- 2004-12-16 AT AT04814409T patent/ATE502298T1/de not_active IP Right Cessation
- 2004-12-16 CA CA002550447A patent/CA2550447A1/en not_active Abandoned
- 2004-12-16 US US10/583,280 patent/US8034548B2/en active Active
- 2004-12-16 NZ NZ548209A patent/NZ548209A/xx unknown
Also Published As
Publication number | Publication date |
---|---|
JP2007514442A (ja) | 2007-06-07 |
ATE502298T1 (de) | 2011-04-15 |
US8034548B2 (en) | 2011-10-11 |
EP2299266A1 (de) | 2011-03-23 |
WO2005060661A2 (en) | 2005-07-07 |
WO2005060661A3 (en) | 2005-08-04 |
CA2550447A1 (en) | 2005-07-07 |
US20070166717A1 (en) | 2007-07-19 |
EP1709193A2 (de) | 2006-10-11 |
EP1709193B1 (de) | 2011-03-16 |
EP1709193A4 (de) | 2007-11-14 |
NZ548209A (en) | 2009-07-31 |
AU2004305075A1 (en) | 2005-07-07 |
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