CY1120434T1 - Πρωτεϊνες προσδεσης il-1 - Google Patents
Πρωτεϊνες προσδεσης il-1Info
- Publication number
- CY1120434T1 CY1120434T1 CY20171100816T CY171100816T CY1120434T1 CY 1120434 T1 CY1120434 T1 CY 1120434T1 CY 20171100816 T CY20171100816 T CY 20171100816T CY 171100816 T CY171100816 T CY 171100816T CY 1120434 T1 CY1120434 T1 CY 1120434T1
- Authority
- CY
- Cyprus
- Prior art keywords
- proteins
- accumulation
- compositions
- accumulation proteins
- bind
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/245—IL-1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61K47/6875—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody being a hybrid immunoglobulin
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Abstract
Περιγράφονται πρωτεΐνες οι οποίες προσδένουν IL-1α και IL-1β μαζί με τη χρήση αυτών σε συνθέσεις και μεθόδους για τη θεραπευτική αγωγή, πρόληψη, και διάγνωση συναφών με IL-1 διαταραχών και για την ανίχνευση IL-1 α και IL-1 β σε κύτταρα, ιστούς, δείγματα, και συνθέσεις.
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US8883146B2 (en) | 2007-11-30 | 2014-11-11 | Abbvie Inc. | Protein formulations and methods of making same |
CA2726087A1 (en) | 2008-06-03 | 2009-12-10 | Tariq Ghayur | Dual variable domain immunoglobulins and uses thereof |
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