KR20210010887A - 유비퀴틴-특이적 펩티다제 30 억제제로서 유용한 융합된 비시클릭 화합물 - Google Patents
유비퀴틴-특이적 펩티다제 30 억제제로서 유용한 융합된 비시클릭 화합물 Download PDFInfo
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- KR20210010887A KR20210010887A KR1020207035718A KR20207035718A KR20210010887A KR 20210010887 A KR20210010887 A KR 20210010887A KR 1020207035718 A KR1020207035718 A KR 1020207035718A KR 20207035718 A KR20207035718 A KR 20207035718A KR 20210010887 A KR20210010887 A KR 20210010887A
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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| US201862687599P | 2018-06-20 | 2018-06-20 | |
| US62/687,599 | 2018-06-20 | ||
| US201862697635P | 2018-07-13 | 2018-07-13 | |
| US62/697,635 | 2018-07-13 | ||
| US201862727164P | 2018-09-05 | 2018-09-05 | |
| US62/727,164 | 2018-09-05 | ||
| PCT/US2019/032619 WO2019222468A1 (en) | 2018-05-17 | 2019-05-16 | Fused bicyclic compounds useful as ubiquitin-specific peptidase 30 inhibitors |
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