KR20170098929A - Hsp47 를 표적으로 하는 rnai 분자를 이용하는 악성 종양에 대한 치료적 조성물 및 방법 - Google Patents

Hsp47 를 표적으로 하는 rnai 분자를 이용하는 악성 종양에 대한 치료적 조성물 및 방법 Download PDF

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KR20170098929A
KR20170098929A KR1020177020894A KR20177020894A KR20170098929A KR 20170098929 A KR20170098929 A KR 20170098929A KR 1020177020894 A KR1020177020894 A KR 1020177020894A KR 20177020894 A KR20177020894 A KR 20177020894A KR 20170098929 A KR20170098929 A KR 20170098929A
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hsp47
artificial sequence
sirna
administration
rnai molecule
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웬빈 잉
아키히로 요네다
야스아키 다무라
겐지로우 미노미
바라트 마제티
지화 리우
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닛토덴코 가부시키가이샤
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KR1020177020894A 2014-12-26 2015-12-28 Hsp47 를 표적으로 하는 rnai 분자를 이용하는 악성 종양에 대한 치료적 조성물 및 방법 Withdrawn KR20170098929A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2014266198 2014-12-26
JPJP-P-2014-266198 2014-12-26
US201562184195P 2015-06-24 2015-06-24
US62/184,195 2015-06-24
US201562266670P 2015-12-13 2015-12-13
US62/266,670 2015-12-13
PCT/US2015/067558 WO2016106403A2 (en) 2014-12-26 2015-12-28 Therapeutic compositions and methods for malignant tumors with rnai molecules targeted to hsp47 and p21

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KR20170098929A true KR20170098929A (ko) 2017-08-30

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Family Applications (4)

Application Number Title Priority Date Filing Date
KR1020177020894A Withdrawn KR20170098929A (ko) 2014-12-26 2015-12-28 Hsp47 를 표적으로 하는 rnai 분자를 이용하는 악성 종양에 대한 치료적 조성물 및 방법
KR1020177020901A Withdrawn KR20170093988A (ko) 2014-12-26 2015-12-28 Gst-pi 유전자 조정을 위한 rna 제제
KR1020177020898A Active KR102527430B1 (ko) 2014-12-26 2015-12-28 Gst-pi 유전자 조정을 위한 rna 간섭 제제
KR1020177020900A Withdrawn KR20170096199A (ko) 2014-12-26 2015-12-28 Kras 돌연변이와 관련된 악성 종양을 치료하기 위한 방법 및 조성물

Family Applications After (3)

Application Number Title Priority Date Filing Date
KR1020177020901A Withdrawn KR20170093988A (ko) 2014-12-26 2015-12-28 Gst-pi 유전자 조정을 위한 rna 제제
KR1020177020898A Active KR102527430B1 (ko) 2014-12-26 2015-12-28 Gst-pi 유전자 조정을 위한 rna 간섭 제제
KR1020177020900A Withdrawn KR20170096199A (ko) 2014-12-26 2015-12-28 Kras 돌연변이와 관련된 악성 종양을 치료하기 위한 방법 및 조성물

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US (14) US10264976B2 (https=)
EP (9) EP3240796B1 (https=)
JP (10) JP2018513669A (https=)
KR (4) KR20170098929A (https=)
CN (7) CN107106591B (https=)
AU (4) AU2015369598A1 (https=)
BR (2) BR112017013599A2 (https=)
CA (4) CA2971881C (https=)
RU (4) RU2756253C2 (https=)
WO (7) WO2016106402A1 (https=)

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PT3236974T (pt) * 2014-12-26 2020-06-01 Nitto Denko Corp Agentes de interferência de rna para modulação génica de gst-pi
US10792299B2 (en) 2014-12-26 2020-10-06 Nitto Denko Corporation Methods and compositions for treating malignant tumors associated with kras mutation
US11045488B2 (en) * 2014-12-26 2021-06-29 Nitto Denko Corporation RNA interference agents for GST-π gene modulation
US20180002702A1 (en) * 2014-12-26 2018-01-04 Nitto Denko Corporation Methods and compositions for treating malignant tumors associated with kras mutation
US10264976B2 (en) * 2014-12-26 2019-04-23 The University Of Akron Biocompatible flavonoid compounds for organelle and cell imaging
US10167253B2 (en) 2015-06-24 2019-01-01 Nitto Denko Corporation Ionizable compounds and compositions and uses thereof
BR112018008344A2 (pt) 2015-12-13 2018-10-30 Nitto Denko Corp molécula de ácido nucleico, composição farmacêutica, vetor ou célula, método para prevenir, tratar ou melhorar uma doença, e, uso de uma composição
AU2017264192B2 (en) 2016-05-10 2023-08-03 National University Corporation Tokyo Medical And Dental University Expression inhibitor of inflammation promoting factors, screening method for active ingredient thereof, expression cassette useful for said method, diagnostic agent and diagnosis method
JP2019508379A (ja) * 2017-02-16 2019-03-28 日東電工株式会社 悪性腫瘍に対する治療方法及び治療用組成物
CN117105811B (zh) * 2017-11-06 2025-12-12 日东电工株式会社 用于递送生物活性分子的膜融合化合物
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