KR20150024919A - 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 - Google Patents
크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 Download PDFInfo
- Publication number
- KR20150024919A KR20150024919A KR20157001953A KR20157001953A KR20150024919A KR 20150024919 A KR20150024919 A KR 20150024919A KR 20157001953 A KR20157001953 A KR 20157001953A KR 20157001953 A KR20157001953 A KR 20157001953A KR 20150024919 A KR20150024919 A KR 20150024919A
- Authority
- KR
- South Korea
- Prior art keywords
- renal
- rats
- group
- substituted
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/04—Drugs for disorders of the urinary system for urolithiasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US85850906P | 2006-11-13 | 2006-11-13 | |
| US60/858,509 | 2006-11-13 | ||
| PCT/US2007/084573 WO2008064015A1 (en) | 2006-11-13 | 2007-11-13 | Methods for preserving renal function using xanthine oxidoreductase inhibitors |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097012310A Division KR20090103879A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167005469A Division KR20160031040A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20150024919A true KR20150024919A (ko) | 2015-03-09 |
Family
ID=39430048
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097012310A Ceased KR20090103879A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
| KR20157001953A Ceased KR20150024919A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
| KR1020167005469A Ceased KR20160031040A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020097012310A Ceased KR20090103879A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020167005469A Ceased KR20160031040A (ko) | 2006-11-13 | 2007-11-13 | 크산틴 옥시도리덕타아제 억제제를 사용하여 신장 기능을 보존하는 방법 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20080269226A1 (enExample) |
| EP (1) | EP2101761A4 (enExample) |
| JP (3) | JP2010509372A (enExample) |
| KR (3) | KR20090103879A (enExample) |
| CN (1) | CN101677999A (enExample) |
| AU (1) | AU2007323919A1 (enExample) |
| BR (1) | BRPI0718611A2 (enExample) |
| CA (1) | CA2669935A1 (enExample) |
| MX (1) | MX2009004984A (enExample) |
| RU (1) | RU2508099C2 (enExample) |
| WO (1) | WO2008064015A1 (enExample) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1883405A4 (en) * | 2005-05-09 | 2010-01-27 | Takeda Pharmaceuticals North A | METHODS OF TREATING NEPHROLITHIASIS |
| US20070167454A1 (en) * | 2005-08-03 | 2007-07-19 | Christopher Lademacher | Methods for treating hypertension |
| US20090124623A1 (en) * | 2006-11-13 | 2009-05-14 | Christopher Lademacher | Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors |
| AU2008206231A1 (en) * | 2007-01-19 | 2008-07-24 | Takeda Pharmaceuticals U.S.A., Inc. | Methods for preventing or reducing the number of gout flares using xanthine oxidoreductase inhibitors and anti-inflammatory agents |
| US20100311756A1 (en) * | 2009-01-22 | 2010-12-09 | Takeda Pharmaceuticals North America, Inc. | Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof |
| IT1400311B1 (it) | 2010-05-10 | 2013-05-24 | Menarini Int Operations Lu Sa | Associazione di inibitori della xantina ossidasi e antagonisti del recettore dell'angiotensina ii e loro uso. |
| IT1400609B1 (it) | 2010-05-10 | 2013-06-14 | Menarini Int Operations Lu Sa | Associazione di inibitori della xantina ossidasi e metformina e loro uso. |
| IT1400310B1 (it) | 2010-05-10 | 2013-05-24 | Menarini Int Operations Lu Sa | Associazione di inibitori della xantina ossidasi e statine e loro uso. |
| IT1400309B1 (it) | 2010-05-10 | 2013-05-24 | Menarini Int Operations Lu Sa | Associazione di inibitori della xantina ossidasi e calcio antagonisti e loro uso. |
| BR112012032033A2 (pt) | 2010-06-16 | 2017-10-31 | Takeda Pharmaceuticals Usa Inc | novas formas de dosagem de libertação modificada de inibidor de xantina oxidorredutase ou inibidores de xantina oxidase |
| US20130109726A1 (en) * | 2010-06-25 | 2013-05-02 | Teijin Pharma Limited | Sustained-release therapeutic agent for hypertension and renal dysfunction |
| CN102372679A (zh) * | 2010-08-27 | 2012-03-14 | 北京润德康医药技术有限公司 | 一种非布司他水溶性衍生物及其制备方法 |
| CA2812034C (en) | 2010-09-10 | 2018-10-23 | Takeda Pharmaceuticals U.S.A., Inc. | Methods for concomitant treatment of theophylline and febuxostat |
| JP5862897B2 (ja) * | 2010-11-01 | 2016-02-16 | 株式会社三和化学研究所 | 腎機能障害の予防又は治療に用いる医薬 |
| CN102757403B (zh) * | 2011-04-27 | 2015-04-29 | 浙江九洲药业股份有限公司 | 一种非布索坦衍生物及其制备方法 |
| TW201328692A (zh) * | 2011-10-11 | 2013-07-16 | Univ Osaka | 脫髓鞘疾病之治療劑及預防劑 |
| TW201334779A (zh) | 2012-01-27 | 2013-09-01 | Teijin Pharma Ltd | 糖尿病的治療藥 |
| WO2014065275A1 (ja) * | 2012-10-23 | 2014-05-01 | 国立大学法人福井大学 | 腫瘍融解症候群の治療薬及び予防薬 |
| CN103265636B (zh) * | 2013-05-23 | 2015-09-16 | 中国药科大学 | 一种具有降血糖作用的新型肽 |
| CN104548066A (zh) * | 2015-01-19 | 2015-04-29 | 中国药科大学 | 一种具有降血糖作用的新型肽的新用途 |
| CN105294584A (zh) * | 2015-11-30 | 2016-02-03 | 中国医科大学 | 1-取代苯基-1h-1,2,3-三唑类化合物、制备方法及其用途 |
| JP6732004B2 (ja) | 2016-02-19 | 2020-07-29 | 国立大学法人鳥取大学 | 認知症治療薬または予防薬 |
| CN106279024B (zh) * | 2016-07-19 | 2018-09-14 | 华南理工大学 | 一种黄嘌呤氧化还原酶抑制剂及其制备方法与应用 |
| KR20230119303A (ko) * | 2022-02-07 | 2023-08-16 | (주)인드림헬스케어 | 높은 혈중 요산 농도를 갖는 대상체의 만성 신장 질환의 예방 또는 치료를 위한 알로푸리놀, 페북소스타트 또는 이들의 약학적으로 허용 가능한 염을 포함하는 약제학적 조성물 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US3079303A (en) * | 1958-12-11 | 1963-02-26 | Smith Kline French Lab | Basic tablet granulation and process of using same |
| US4058614A (en) * | 1973-12-04 | 1977-11-15 | Merck & Co., Inc. | Substituted imidazole compounds and therapeutic compositions therewith |
| US4296122A (en) * | 1975-07-09 | 1981-10-20 | Merck & Co., Inc. | 2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids |
| DE2727802A1 (de) * | 1977-06-21 | 1979-04-19 | Hoechst Ag | Sulfamoyl-arylketone und verfahren zu ihrer herstellung |
| US4510322A (en) * | 1981-07-13 | 1985-04-09 | Merck & Co., Inc. | Indacrinone having enhanced uricosuric |
| US4632930A (en) * | 1984-11-30 | 1986-12-30 | E. I. Du Pont De Nemours And Company | Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives |
| US5047246A (en) * | 1988-09-09 | 1991-09-10 | Bristol-Myers Company | Direct compression cyclophosphamide tablet |
| JPH0366669A (ja) * | 1989-08-03 | 1991-03-22 | Shionogi & Co Ltd | 複素環式化合物 |
| JP2725886B2 (ja) * | 1990-11-30 | 1998-03-11 | 帝人株式会社 | 2―アリールチアゾール誘導体及びその医薬組成物 |
| US5358961A (en) * | 1991-11-30 | 1994-10-25 | Jin Ro Limited | Pyrrolidine derivatives |
| SE9301830D0 (sv) * | 1993-05-28 | 1993-05-28 | Ab Astra | New compounds |
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| US5770601A (en) * | 1994-08-17 | 1998-06-23 | Virginia Tech Intellectual Properties, Inc. | Compositions and methods for controlling pest insects |
| AUPM835394A0 (en) * | 1994-09-23 | 1994-10-13 | King, Michael G. Dr. | Method for controlling or eliminating the need to smoke tobacco, and for treating ailments which may lead to the said need |
| CA2190993C (en) * | 1995-04-07 | 2004-06-01 | Mikio Ota | Protective agent for organ or tissue |
| ID21775A (id) * | 1996-10-25 | 1999-07-22 | Yoshitomi Pharmaceutical | Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya |
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| EP1044002A4 (en) * | 1997-11-07 | 2003-05-02 | Univ Johns Hopkins | METHODS FOR THE TREATMENT OF HEART CONTRACTILITY |
| CZ298170B6 (cs) * | 1998-06-19 | 2007-07-11 | Teijin Limited | Polymorfní a amorfní modifikace 2-(3-kyan-4-isobutoxyfenyl)-4-methyl-5-thiazolkarboxylové kyseliny a zpusob jejich prípravy |
| US6281222B1 (en) * | 1999-08-19 | 2001-08-28 | Inotek Corporation | Compositions and method for treatment of acetaminophen intoxication |
| US7799794B2 (en) * | 2000-06-28 | 2010-09-21 | Merck Sharp & Dohme Corp. | Treatment for cardiovascular disease |
| ITMI20010206A1 (it) * | 2001-02-02 | 2002-08-02 | Dompe Spa | Uso della metansolfonammide di (r)-ibuprofene e dei suoi sali non tossici per la preparazione di medicamenti per il trattamento e la prevenz |
| EP1416942B1 (en) * | 2001-04-18 | 2007-12-12 | Genzyme Corporation | Amine polymers for treating gout and binding uric acid |
| WO2002085380A1 (en) * | 2001-04-18 | 2002-10-31 | Geltex Pharmaceuticals, Inc. | Method for treating gout and reducing serum uric acid |
| RU2293733C2 (ru) * | 2002-01-28 | 2007-02-20 | Фуджи Якухин Ко., Лтд. | Новые 1,2,4-триазольные соединения, способы их получения и содержащие их лекарственные средства |
| SI1488790T1 (sl) * | 2002-03-28 | 2014-09-30 | Teijin Pharma Limited | Trden pripravek, ki vsebuje eno samo kristalno a-obliko derivata tiazolkarboksilne kisline |
| US20060040945A1 (en) * | 2002-05-17 | 2006-02-23 | Merckle Gmbh | Annellated pyrrole compounds as proton pump inhibitors for treating ulcer |
| US7078423B2 (en) * | 2002-07-18 | 2006-07-18 | Inotek Pharmaceuticals Corporation | 5-Aryltetrazole compounds, compositions thereof, and uses therefor |
| US20040121004A1 (en) * | 2002-12-20 | 2004-06-24 | Rajneesh Taneja | Dosage forms containing a PPI, NSAID, and buffer |
| US20040131676A1 (en) * | 2002-12-20 | 2004-07-08 | Rajneesh Taneja | Dosage forms containing a PPI, NSAID, and buffer |
| US20040122067A1 (en) * | 2002-12-20 | 2004-06-24 | Lin Zhao | Treatment of chronic heart failure |
| WO2005018635A2 (en) * | 2003-08-07 | 2005-03-03 | Cardiome Pharma Corp. | Ion channel modulating activity i |
| WO2006028342A1 (en) * | 2004-09-06 | 2006-03-16 | Biosynergen, Inc. | A novel xanthine oxidase inhibitor and a pharmaceutical composition containing the same |
| EP1819334A1 (en) * | 2004-11-19 | 2007-08-22 | Shiva Biomedical, LLC | Methods of treating erythropoietin-resistance |
| EP1883405A4 (en) * | 2005-05-09 | 2010-01-27 | Takeda Pharmaceuticals North A | METHODS OF TREATING NEPHROLITHIASIS |
| US20070167454A1 (en) * | 2005-08-03 | 2007-07-19 | Christopher Lademacher | Methods for treating hypertension |
| US20090124623A1 (en) * | 2006-11-13 | 2009-05-14 | Christopher Lademacher | Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors |
| AU2008206231A1 (en) * | 2007-01-19 | 2008-07-24 | Takeda Pharmaceuticals U.S.A., Inc. | Methods for preventing or reducing the number of gout flares using xanthine oxidoreductase inhibitors and anti-inflammatory agents |
| US20100311756A1 (en) * | 2009-01-22 | 2010-12-09 | Takeda Pharmaceuticals North America, Inc. | Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof |
| CA2812034C (en) * | 2010-09-10 | 2018-10-23 | Takeda Pharmaceuticals U.S.A., Inc. | Methods for concomitant treatment of theophylline and febuxostat |
-
2007
- 2007-11-13 MX MX2009004984A patent/MX2009004984A/es unknown
- 2007-11-13 US US11/939,112 patent/US20080269226A1/en not_active Abandoned
- 2007-11-13 BR BRPI0718611-8A2A patent/BRPI0718611A2/pt not_active IP Right Cessation
- 2007-11-13 JP JP2009536541A patent/JP2010509372A/ja active Pending
- 2007-11-13 CN CN200780049607A patent/CN101677999A/zh active Pending
- 2007-11-13 EP EP07864338A patent/EP2101761A4/en not_active Withdrawn
- 2007-11-13 RU RU2009122505/15A patent/RU2508099C2/ru not_active IP Right Cessation
- 2007-11-13 KR KR1020097012310A patent/KR20090103879A/ko not_active Ceased
- 2007-11-13 CA CA002669935A patent/CA2669935A1/en not_active Abandoned
- 2007-11-13 WO PCT/US2007/084573 patent/WO2008064015A1/en not_active Ceased
- 2007-11-13 KR KR20157001953A patent/KR20150024919A/ko not_active Ceased
- 2007-11-13 KR KR1020167005469A patent/KR20160031040A/ko not_active Ceased
- 2007-11-13 AU AU2007323919A patent/AU2007323919A1/en not_active Abandoned
-
2013
- 2013-09-20 JP JP2013195396A patent/JP2014012726A/ja active Pending
-
2016
- 2016-06-08 JP JP2016114133A patent/JP6233899B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN101677999A (zh) | 2010-03-24 |
| AU2007323919A1 (en) | 2008-05-29 |
| BRPI0718611A2 (pt) | 2014-02-25 |
| KR20090103879A (ko) | 2009-10-01 |
| US20080269226A1 (en) | 2008-10-30 |
| EP2101761A1 (en) | 2009-09-23 |
| JP6233899B2 (ja) | 2017-11-22 |
| JP2014012726A (ja) | 2014-01-23 |
| WO2008064015A1 (en) | 2008-05-29 |
| MX2009004984A (es) | 2009-09-23 |
| KR20160031040A (ko) | 2016-03-21 |
| JP2010509372A (ja) | 2010-03-25 |
| RU2009122505A (ru) | 2010-12-20 |
| CA2669935A1 (en) | 2008-05-29 |
| RU2508099C2 (ru) | 2014-02-27 |
| JP2016188231A (ja) | 2016-11-04 |
| EP2101761A4 (en) | 2010-01-27 |
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