CN101677999A - 使用黄嘌呤氧化还原酶抑制剂保护肾功能的方法 - Google Patents

使用黄嘌呤氧化还原酶抑制剂保护肾功能的方法 Download PDF

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Publication number
CN101677999A
CN101677999A CN200780049607A CN200780049607A CN101677999A CN 101677999 A CN101677999 A CN 101677999A CN 200780049607 A CN200780049607 A CN 200780049607A CN 200780049607 A CN200780049607 A CN 200780049607A CN 101677999 A CN101677999 A CN 101677999A
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group
phenyl
experimenter
unsubstituted
methyl
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Chinese (zh)
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C·拉德马赫
P·麦唐纳
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Tap Pharmaceuticals Inc
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Tap Pharmaceuticals Inc
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Publication of CN101677999A publication Critical patent/CN101677999A/zh
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
CN200780049607A 2006-11-13 2007-11-13 使用黄嘌呤氧化还原酶抑制剂保护肾功能的方法 Pending CN101677999A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85850906P 2006-11-13 2006-11-13
US60/858,509 2006-11-13
PCT/US2007/084573 WO2008064015A1 (en) 2006-11-13 2007-11-13 Methods for preserving renal function using xanthine oxidoreductase inhibitors

Publications (1)

Publication Number Publication Date
CN101677999A true CN101677999A (zh) 2010-03-24

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Family Applications (1)

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CN200780049607A Pending CN101677999A (zh) 2006-11-13 2007-11-13 使用黄嘌呤氧化还原酶抑制剂保护肾功能的方法

Country Status (11)

Country Link
US (1) US20080269226A1 (enExample)
EP (1) EP2101761A4 (enExample)
JP (3) JP2010509372A (enExample)
KR (3) KR20090103879A (enExample)
CN (1) CN101677999A (enExample)
AU (1) AU2007323919A1 (enExample)
BR (1) BRPI0718611A2 (enExample)
CA (1) CA2669935A1 (enExample)
MX (1) MX2009004984A (enExample)
RU (1) RU2508099C2 (enExample)
WO (1) WO2008064015A1 (enExample)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102372679A (zh) * 2010-08-27 2012-03-14 北京润德康医药技术有限公司 一种非布司他水溶性衍生物及其制备方法
CN102757403A (zh) * 2011-04-27 2012-10-31 浙江九洲药业股份有限公司 一种非布索坦衍生物及其制备方法
CN102958521A (zh) * 2010-06-25 2013-03-06 帝人制药株式会社 缓释性高血压和肾功能不全治疗剂
CN103265636A (zh) * 2013-05-23 2013-08-28 中国药科大学 一种具有降血糖作用的新型肽
CN104548066A (zh) * 2015-01-19 2015-04-29 中国药科大学 一种具有降血糖作用的新型肽的新用途
CN104981242A (zh) * 2012-10-23 2015-10-14 帝人制药株式会社 肿瘤溶解综合征的治疗药和预防药
CN106279024A (zh) * 2016-07-19 2017-01-04 华南理工大学 一种黄嘌呤氧化还原酶抑制剂及其制备方法与应用

Families Citing this family (17)

* Cited by examiner, † Cited by third party
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CA2607953A1 (en) * 2005-05-09 2006-11-16 Tap Pharmaceutical Products, Inc. Methods for treating nephrolithiasis
WO2007019153A2 (en) * 2005-08-03 2007-02-15 Tap Pharmaceutical Products, Inc. Methods for treating hypertension
US20090124623A1 (en) * 2006-11-13 2009-05-14 Christopher Lademacher Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors
AU2008206231A1 (en) * 2007-01-19 2008-07-24 Takeda Pharmaceuticals U.S.A., Inc. Methods for preventing or reducing the number of gout flares using xanthine oxidoreductase inhibitors and anti-inflammatory agents
US20100311756A1 (en) * 2009-01-22 2010-12-09 Takeda Pharmaceuticals North America, Inc. Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof
IT1400311B1 (it) 2010-05-10 2013-05-24 Menarini Int Operations Lu Sa Associazione di inibitori della xantina ossidasi e antagonisti del recettore dell'angiotensina ii e loro uso.
IT1400309B1 (it) 2010-05-10 2013-05-24 Menarini Int Operations Lu Sa Associazione di inibitori della xantina ossidasi e calcio antagonisti e loro uso.
IT1400310B1 (it) 2010-05-10 2013-05-24 Menarini Int Operations Lu Sa Associazione di inibitori della xantina ossidasi e statine e loro uso.
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ES2669184T3 (es) 2010-06-16 2018-05-24 Takeda Pharmaceuticals U.S.A., Inc. Nuevas formas de dosificación de liberación modificada de inhibidor de xantina oxidorreductasa o inhibidores de xantina oxidasa
CN103298466B (zh) 2010-09-10 2015-11-25 武田制药美国有限公司 茶碱和非布索坦的联合治疗方法
JP5862897B2 (ja) * 2010-11-01 2016-02-16 株式会社三和化学研究所 腎機能障害の予防又は治療に用いる医薬
TW201328692A (zh) * 2011-10-11 2013-07-16 Univ Osaka 脫髓鞘疾病之治療劑及預防劑
CN104066430A (zh) 2012-01-27 2014-09-24 帝人制药株式会社 糖尿病的治疗药
CN105294584A (zh) * 2015-11-30 2016-02-03 中国医科大学 1-取代苯基-1h-1,2,3-三唑类化合物、制备方法及其用途
AR107661A1 (es) 2016-02-19 2018-05-23 Nat Univ Corp Tottori Univ Agente terapéutico o profiláctico para la demencia
KR20230119303A (ko) * 2022-02-07 2023-08-16 (주)인드림헬스케어 높은 혈중 요산 농도를 갖는 대상체의 만성 신장 질환의 예방 또는 치료를 위한 알로푸리놀, 페북소스타트 또는 이들의 약학적으로 허용 가능한 염을 포함하는 약제학적 조성물

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Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102958521A (zh) * 2010-06-25 2013-03-06 帝人制药株式会社 缓释性高血压和肾功能不全治疗剂
CN102372679A (zh) * 2010-08-27 2012-03-14 北京润德康医药技术有限公司 一种非布司他水溶性衍生物及其制备方法
CN102757403A (zh) * 2011-04-27 2012-10-31 浙江九洲药业股份有限公司 一种非布索坦衍生物及其制备方法
CN102757403B (zh) * 2011-04-27 2015-04-29 浙江九洲药业股份有限公司 一种非布索坦衍生物及其制备方法
CN104981242A (zh) * 2012-10-23 2015-10-14 帝人制药株式会社 肿瘤溶解综合征的治疗药和预防药
CN103265636A (zh) * 2013-05-23 2013-08-28 中国药科大学 一种具有降血糖作用的新型肽
CN103265636B (zh) * 2013-05-23 2015-09-16 中国药科大学 一种具有降血糖作用的新型肽
CN104548066A (zh) * 2015-01-19 2015-04-29 中国药科大学 一种具有降血糖作用的新型肽的新用途
CN106279024A (zh) * 2016-07-19 2017-01-04 华南理工大学 一种黄嘌呤氧化还原酶抑制剂及其制备方法与应用

Also Published As

Publication number Publication date
JP2014012726A (ja) 2014-01-23
RU2009122505A (ru) 2010-12-20
US20080269226A1 (en) 2008-10-30
CA2669935A1 (en) 2008-05-29
KR20150024919A (ko) 2015-03-09
EP2101761A4 (en) 2010-01-27
JP2010509372A (ja) 2010-03-25
MX2009004984A (es) 2009-09-23
KR20090103879A (ko) 2009-10-01
EP2101761A1 (en) 2009-09-23
AU2007323919A1 (en) 2008-05-29
JP2016188231A (ja) 2016-11-04
JP6233899B2 (ja) 2017-11-22
RU2508099C2 (ru) 2014-02-27
KR20160031040A (ko) 2016-03-21
BRPI0718611A2 (pt) 2014-02-25
WO2008064015A1 (en) 2008-05-29

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