RU2508099C2 - Способы сохранения функции почек с использованием ингибиторов ксантин оксидоредуктазы - Google Patents

Способы сохранения функции почек с использованием ингибиторов ксантин оксидоредуктазы Download PDF

Info

Publication number
RU2508099C2
RU2508099C2 RU2009122505/15A RU2009122505A RU2508099C2 RU 2508099 C2 RU2508099 C2 RU 2508099C2 RU 2009122505/15 A RU2009122505/15 A RU 2009122505/15A RU 2009122505 A RU2009122505 A RU 2009122505A RU 2508099 C2 RU2508099 C2 RU 2508099C2
Authority
RU
Russia
Prior art keywords
subject
group
gfr
kidney
renal function
Prior art date
Application number
RU2009122505/15A
Other languages
English (en)
Russian (ru)
Other versions
RU2009122505A (ru
Inventor
Кристофер ЛАДЕМАХЕР
Патрисия МАКДОНАЛЬД
Original Assignee
Такеда Фармасьютикалз Норт Америка, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Такеда Фармасьютикалз Норт Америка, Инк. filed Critical Такеда Фармасьютикалз Норт Америка, Инк.
Publication of RU2009122505A publication Critical patent/RU2009122505A/ru
Application granted granted Critical
Publication of RU2508099C2 publication Critical patent/RU2508099C2/ru

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/04Drugs for disorders of the urinary system for urolithiasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
RU2009122505/15A 2006-11-13 2007-11-13 Способы сохранения функции почек с использованием ингибиторов ксантин оксидоредуктазы RU2508099C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85850906P 2006-11-13 2006-11-13
US60/858,509 2006-11-13
PCT/US2007/084573 WO2008064015A1 (en) 2006-11-13 2007-11-13 Methods for preserving renal function using xanthine oxidoreductase inhibitors

Publications (2)

Publication Number Publication Date
RU2009122505A RU2009122505A (ru) 2010-12-20
RU2508099C2 true RU2508099C2 (ru) 2014-02-27

Family

ID=39430048

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2009122505/15A RU2508099C2 (ru) 2006-11-13 2007-11-13 Способы сохранения функции почек с использованием ингибиторов ксантин оксидоредуктазы

Country Status (11)

Country Link
US (1) US20080269226A1 (enExample)
EP (1) EP2101761A4 (enExample)
JP (3) JP2010509372A (enExample)
KR (3) KR20160031040A (enExample)
CN (1) CN101677999A (enExample)
AU (1) AU2007323919A1 (enExample)
BR (1) BRPI0718611A2 (enExample)
CA (1) CA2669935A1 (enExample)
MX (1) MX2009004984A (enExample)
RU (1) RU2508099C2 (enExample)
WO (1) WO2008064015A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2607953A1 (en) * 2005-05-09 2006-11-16 Tap Pharmaceutical Products, Inc. Methods for treating nephrolithiasis
JP5242393B2 (ja) * 2005-08-03 2013-07-24 タケダ ファーマシューティカルズ ユー.エス.エー. インコーポレイティド 高血圧症の治療方法
US20090124623A1 (en) * 2006-11-13 2009-05-14 Christopher Lademacher Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors
AU2008206231A1 (en) * 2007-01-19 2008-07-24 Takeda Pharmaceuticals U.S.A., Inc. Methods for preventing or reducing the number of gout flares using xanthine oxidoreductase inhibitors and anti-inflammatory agents
US20100311756A1 (en) * 2009-01-22 2010-12-09 Takeda Pharmaceuticals North America, Inc. Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof
IT1400609B1 (it) 2010-05-10 2013-06-14 Menarini Int Operations Lu Sa Associazione di inibitori della xantina ossidasi e metformina e loro uso.
IT1400309B1 (it) 2010-05-10 2013-05-24 Menarini Int Operations Lu Sa Associazione di inibitori della xantina ossidasi e calcio antagonisti e loro uso.
IT1400310B1 (it) 2010-05-10 2013-05-24 Menarini Int Operations Lu Sa Associazione di inibitori della xantina ossidasi e statine e loro uso.
IT1400311B1 (it) 2010-05-10 2013-05-24 Menarini Int Operations Lu Sa Associazione di inibitori della xantina ossidasi e antagonisti del recettore dell'angiotensina ii e loro uso.
US9248119B2 (en) 2010-06-16 2016-02-02 Takeda Pharmaceuticals U.S.A., Inc. Modified release dosage forms of xanthine oxidoreductase inhibitor or xanthine oxidase inhibitors
PH12012502487A1 (en) * 2010-06-25 2017-08-09 Teijin Pharma Ltd Sustained-release therapeutic agent for hypertension and renal dysfunction
CN102372679A (zh) * 2010-08-27 2012-03-14 北京润德康医药技术有限公司 一种非布司他水溶性衍生物及其制备方法
ES2532210T3 (es) 2010-09-10 2015-03-25 Takeda Pharmaceuticals U.S.A., Inc. Métodos para el tratamiento concomitante de teofilina y febuxostat
WO2012060308A1 (ja) * 2010-11-01 2012-05-10 株式会社 三和化学研究所 腎機能障害の予防又は治療に用いる医薬
CN102757403B (zh) * 2011-04-27 2015-04-29 浙江九洲药业股份有限公司 一种非布索坦衍生物及其制备方法
TW201328692A (zh) 2011-10-11 2013-07-16 Univ Osaka 脫髓鞘疾病之治療劑及預防劑
CA2862602A1 (en) 2012-01-27 2013-08-01 Teijin Pharma Limited Therapeutic agent for diabetes
CN104981242A (zh) * 2012-10-23 2015-10-14 帝人制药株式会社 肿瘤溶解综合征的治疗药和预防药
CN103265636B (zh) * 2013-05-23 2015-09-16 中国药科大学 一种具有降血糖作用的新型肽
CN104548066A (zh) * 2015-01-19 2015-04-29 中国药科大学 一种具有降血糖作用的新型肽的新用途
CN105294584A (zh) * 2015-11-30 2016-02-03 中国医科大学 1-取代苯基-1h-1,2,3-三唑类化合物、制备方法及其用途
US11344539B2 (en) 2016-02-19 2022-05-31 National University Corporation Tottori University Therapeutic or prophylactic drug for dementia
CN106279024B (zh) * 2016-07-19 2018-09-14 华南理工大学 一种黄嘌呤氧化还原酶抑制剂及其制备方法与应用
KR20230119303A (ko) * 2022-02-07 2023-08-16 (주)인드림헬스케어 높은 혈중 요산 농도를 갖는 대상체의 만성 신장 질환의 예방 또는 치료를 위한 알로푸리놀, 페북소스타트 또는 이들의 약학적으로 허용 가능한 염을 포함하는 약제학적 조성물

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268386A (en) * 1989-08-03 1993-12-07 Shionogi & Co., Ltd. Certain 3,4-dihydro 4-oxospiro [2H-1 benzopyrans] useful for treating hyperuricemia
RU2257895C2 (ru) * 2001-02-02 2005-08-10 Домпе С.П.А. Применение (r)-ибупрофенметансульфонамида и его солей для лечения и предотвращения реакций отторжения трансплантируемых органов
US20060252808A1 (en) * 2005-05-09 2006-11-09 Nancy Joseph-Ridge Methods for treating nephrolithiasis

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3079303A (en) * 1958-12-11 1963-02-26 Smith Kline French Lab Basic tablet granulation and process of using same
US4058614A (en) * 1973-12-04 1977-11-15 Merck & Co., Inc. Substituted imidazole compounds and therapeutic compositions therewith
US4296122A (en) * 1975-07-09 1981-10-20 Merck & Co., Inc. 2,3-Dihydro-6,7-disubstituted-5-(acyl)benzofuran-2-carboxylic acids
DE2727802A1 (de) * 1977-06-21 1979-04-19 Hoechst Ag Sulfamoyl-arylketone und verfahren zu ihrer herstellung
US4510322A (en) * 1981-07-13 1985-04-09 Merck & Co., Inc. Indacrinone having enhanced uricosuric
US4632930A (en) * 1984-11-30 1986-12-30 E. I. Du Pont De Nemours And Company Antihypertensive alkyl-arylimidazole, thiazole and oxazole derivatives
US5047246A (en) * 1988-09-09 1991-09-10 Bristol-Myers Company Direct compression cyclophosphamide tablet
DE122008000051I1 (de) * 1990-11-30 2009-02-05 Teijin Ltd 2-arylthiazolderivat sowie dieses enthaltendes arzneimittel
US5358961A (en) * 1991-11-30 1994-10-25 Jin Ro Limited Pyrrolidine derivatives
SE9301830D0 (sv) * 1993-05-28 1993-05-28 Ab Astra New compounds
US5770601A (en) * 1994-08-17 1998-06-23 Virginia Tech Intellectual Properties, Inc. Compositions and methods for controlling pest insects
US5514681A (en) * 1994-08-17 1996-05-07 Virginia Tech Intellectual Properties, Inc. Compositions and methods for controlling pest insects
US6037344A (en) * 1994-08-17 2000-03-14 Virginia Tech Intellectual Properties, Inc. Compositions and methods for controlling pest insects
AUPM835394A0 (en) * 1994-09-23 1994-10-13 King, Michael G. Dr. Method for controlling or eliminating the need to smoke tobacco, and for treating ailments which may lead to the said need
KR100308332B1 (ko) * 1995-04-07 2002-09-17 데이진 가부시키가이샤 기관또는조직보호제
ID21775A (id) * 1996-10-25 1999-07-22 Yoshitomi Pharmaceutical Senyawa-senyawa 1-fenilpirazol dan penggunaan farmasinya
US5965625A (en) * 1997-03-21 1999-10-12 King; Michael Glenn Compositions and methods for the control of smoking
WO1999024038A1 (en) * 1997-11-07 1999-05-20 Johns Hopkins University Methods for treatment of disorders of cardiac contractility
SK287928B6 (sk) * 1998-06-19 2012-04-03 Teijin Pharma Limited Polymorphic modifications of 2-(3-cyano-4-isobutyloxyphenyl)-4- methyl-5-thiazole-carboxylic acid and processes for the preparation thereof
US6281222B1 (en) * 1999-08-19 2001-08-28 Inotek Corporation Compositions and method for treatment of acetaminophen intoxication
AU2001268734A1 (en) * 2000-06-28 2002-01-08 Merck & Co., Inc. Use of agents capable of reducing uric acid levels for the treatment of cardiovascular disease
ATE380553T1 (de) * 2001-04-18 2007-12-15 Genzyme Corp Aminpolymere zur behandlung von gicht und zur senkung des harnsäuregehaltes
WO2002085380A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for treating gout and reducing serum uric acid
MXPA04004037A (es) * 2002-01-28 2004-07-23 Fuji Yakuhin Co Ltd Compuestos novedosos de 1, 2, 4-de triazol.
SI1488790T1 (sl) * 2002-03-28 2014-09-30 Teijin Pharma Limited Trden pripravek, ki vsebuje eno samo kristalno a-obliko derivata tiazolkarboksilne kisline
US20060040945A1 (en) * 2002-05-17 2006-02-23 Merckle Gmbh Annellated pyrrole compounds as proton pump inhibitors for treating ulcer
US7078423B2 (en) * 2002-07-18 2006-07-18 Inotek Pharmaceuticals Corporation 5-Aryltetrazole compounds, compositions thereof, and uses therefor
US20040121004A1 (en) * 2002-12-20 2004-06-24 Rajneesh Taneja Dosage forms containing a PPI, NSAID, and buffer
US20040131676A1 (en) * 2002-12-20 2004-07-08 Rajneesh Taneja Dosage forms containing a PPI, NSAID, and buffer
US20040122067A1 (en) * 2002-12-20 2004-06-24 Lin Zhao Treatment of chronic heart failure
US7674820B2 (en) * 2003-08-07 2010-03-09 Cardiome Pharma Corp. Ion channel modulating activity I
WO2006028342A1 (en) * 2004-09-06 2006-03-16 Biosynergen, Inc. A novel xanthine oxidase inhibitor and a pharmaceutical composition containing the same
CA2587558A1 (en) * 2004-11-19 2006-05-26 Shiva Biomedical, Llc Methods of treating erythropoietin-resistance
JP5242393B2 (ja) * 2005-08-03 2013-07-24 タケダ ファーマシューティカルズ ユー.エス.エー. インコーポレイティド 高血圧症の治療方法
US20090124623A1 (en) * 2006-11-13 2009-05-14 Christopher Lademacher Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors
AU2008206231A1 (en) * 2007-01-19 2008-07-24 Takeda Pharmaceuticals U.S.A., Inc. Methods for preventing or reducing the number of gout flares using xanthine oxidoreductase inhibitors and anti-inflammatory agents
US20100311756A1 (en) * 2009-01-22 2010-12-09 Takeda Pharmaceuticals North America, Inc. Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof
ES2532210T3 (es) * 2010-09-10 2015-03-25 Takeda Pharmaceuticals U.S.A., Inc. Métodos para el tratamiento concomitante de teofilina y febuxostat

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5268386A (en) * 1989-08-03 1993-12-07 Shionogi & Co., Ltd. Certain 3,4-dihydro 4-oxospiro [2H-1 benzopyrans] useful for treating hyperuricemia
RU2257895C2 (ru) * 2001-02-02 2005-08-10 Домпе С.П.А. Применение (r)-ибупрофенметансульфонамида и его солей для лечения и предотвращения реакций отторжения трансплантируемых органов
US20060252808A1 (en) * 2005-05-09 2006-11-09 Nancy Joseph-Ridge Methods for treating nephrolithiasis

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
FUKUNARI A. et al. Y-700 [1,3-cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid: a potent xanthine oxidoreductase ingibitor with hepatic excrection // The Journal of Pharmacology and Experimental Therapeuticus, 2004, vol. 311, №2, pp.519-528. *
ЕРОХИН А.П. и др. Крипторхизм. - М., 1995, с.209. *
ЕРОХИН А.П. и др. Крипторхизм. - М., 1995, с.209. FUKUNARI A. et al. Y-700 [1,3-cyano-4-(2,2-dimethylpropoxy)phenyl]-1H-pyrazole-4-carboxylic acid: a potent xanthine oxidoreductase ingibitor with hepatic excrection // The Journal of Pharmacology and Experimental Therapeuticus, 2004, vol. 311, No.2, pp.519-528. *

Also Published As

Publication number Publication date
KR20090103879A (ko) 2009-10-01
JP6233899B2 (ja) 2017-11-22
EP2101761A1 (en) 2009-09-23
CN101677999A (zh) 2010-03-24
BRPI0718611A2 (pt) 2014-02-25
AU2007323919A1 (en) 2008-05-29
JP2014012726A (ja) 2014-01-23
JP2016188231A (ja) 2016-11-04
KR20160031040A (ko) 2016-03-21
US20080269226A1 (en) 2008-10-30
EP2101761A4 (en) 2010-01-27
WO2008064015A1 (en) 2008-05-29
RU2009122505A (ru) 2010-12-20
CA2669935A1 (en) 2008-05-29
KR20150024919A (ko) 2015-03-09
JP2010509372A (ja) 2010-03-25
MX2009004984A (es) 2009-09-23

Similar Documents

Publication Publication Date Title
JP6233899B2 (ja) キサンチン酸化還元酵素阻害剤を使用する腎機能保持方法
US20130143886A1 (en) Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors
US20140329868A1 (en) Methods for treating hypertension
Sánchez-Lozada et al. Effect of febuxostat on the progression of renal disease in 5/6 nephrectomy rats with and without hyperuricemia
KR101607081B1 (ko) 디피피-4 저해약과 다른 당뇨병 치료약과의 병용 또는 조합으로 이루어지는 의약
JP2010516691A (ja) 抗炎症剤及びキサンチン酸化還元酵素阻害剤を用いて痛風の突発を抑え、又はその数を減少させる方法
KR20080081354A (ko) 당뇨병 치료제
US20100311756A1 (en) Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof
Connelly et al. The SGLT2i dapagliflozin reduces RV mass independent of changes in RV pressure induced by pulmonary artery banding
JPH04211020A (ja) トロンボキサンシンセターゼ阻害剤および/またはトロンボキサンレセプター拮抗剤またはそれらの組合せを用いて血清尿酸を減少させそして/または直腸の尿酸クリアランスを増加させる方法
JP4096122B2 (ja) 心臓線維芽細胞の増殖および心線維症を抑制する方法
US20070026079A1 (en) Intranasal administration of modulators of hypothalamic ATP-sensitive potassium channels
EP0641569A1 (en) Antipruritic
US20240226070A1 (en) Urat1 inhibitor, pharmaceutical compositions and uses thereof
JP4426654B2 (ja) 免疫調節用医薬組成物
Connelly et al. The SGLT2i Dapagliflozin Reduces RV Hypertrophy Independent of Changes in RV Pressure Induced by Pulmonary Artery Banding
WO2025100427A1 (ja) 肺高血圧症の予防および/または治療用医薬
KR100731870B1 (ko) 알러지성 질환 치료용 약학적 조성물
JPH10310524A (ja) 糖尿病合併症予防薬又は治療薬
US20080317728A1 (en) Lowering Uric Acid to Prevent or Accelerate Recovery of Acute Renal Failure
HK40115454A (zh) 用於治疗或预防衰老相关病症的苯并二氢吡喃醇化合物
JP2006182677A (ja) 尿細管間質障害の治療及び/又は予防剤
Boldt PDE-III inhibitors
WO2019087239A1 (ja) 腎症治療剤

Legal Events

Date Code Title Description
MM4A The patent is invalid due to non-payment of fees

Effective date: 20161114