KR102833111B1 - 칼슘 알파-케토글루타레이트의 제조 방법 - Google Patents

칼슘 알파-케토글루타레이트의 제조 방법 Download PDF

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KR102833111B1
KR102833111B1 KR1020217010402A KR20217010402A KR102833111B1 KR 102833111 B1 KR102833111 B1 KR 102833111B1 KR 1020217010402 A KR1020217010402 A KR 1020217010402A KR 20217010402 A KR20217010402 A KR 20217010402A KR 102833111 B1 KR102833111 B1 KR 102833111B1
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alpha
water
ketoglutarate
ketoglutaric acid
mixture
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KR20210065120A (ko
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데이비드 유진 페레이라
케샤브 데오
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폰세 드 리온 헬스 데지그네이티드 액티비티 컴퍼니
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/41—Preparation of salts of carboxylic acids
    • C07C51/418—Preparation of metal complexes containing carboxylic acid moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/347—Saturated compounds containing more than one carboxyl group containing keto groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
KR1020217010402A 2018-09-25 2019-09-23 칼슘 알파-케토글루타레이트의 제조 방법 Active KR102833111B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862736320P 2018-09-25 2018-09-25
US62/736,320 2018-09-25
PCT/US2019/052498 WO2020068705A1 (en) 2018-09-25 2019-09-23 Process of making calcium alpha-ketoglutarate

Publications (2)

Publication Number Publication Date
KR20210065120A KR20210065120A (ko) 2021-06-03
KR102833111B1 true KR102833111B1 (ko) 2025-07-10

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KR1020217010402A Active KR102833111B1 (ko) 2018-09-25 2019-09-23 칼슘 알파-케토글루타레이트의 제조 방법

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US (1) US11802103B2 (enExample)
EP (1) EP3856166A4 (enExample)
JP (1) JP7499259B2 (enExample)
KR (1) KR102833111B1 (enExample)
CN (1) CN112955139B (enExample)
AU (1) AU2019350699B2 (enExample)
BR (1) BR112021005668A2 (enExample)
CA (1) CA3112205A1 (enExample)
CL (1) CL2021000728A1 (enExample)
CO (1) CO2021004529A2 (enExample)
IL (1) IL281761B2 (enExample)
MX (1) MX2021003482A (enExample)
MY (1) MY203278A (enExample)
PE (1) PE20211816A1 (enExample)
PH (1) PH12021550403A1 (enExample)
SG (1) SG11202102204PA (enExample)
TW (1) TWI863930B (enExample)
WO (1) WO2020068705A1 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102833111B1 (ko) 2018-09-25 2025-07-10 폰세 드 리온 헬스 데지그네이티드 액티비티 컴퍼니 칼슘 알파-케토글루타레이트의 제조 방법
CN112941116B (zh) * 2021-01-04 2022-12-02 上海朴颐化学科技有限公司 一种酶法制备α-酮戊二酸钙的方法
CN114105761B (zh) * 2021-11-19 2024-06-21 广东派特埃尔生物科技有限公司 一种α-酮戊二酸钠盐的合成工艺
CN115974679A (zh) * 2022-12-20 2023-04-18 绍兴市精益生物化工有限公司 α-酮戊二酸钙盐制备方法
CN119977789A (zh) * 2025-02-12 2025-05-13 江苏惠利生物科技有限公司 一种离子交换树脂制备高纯度α-酮戊二酸钙的方法

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US11802103B2 (en) 2023-10-31
JP2022502489A (ja) 2022-01-11
BR112021005668A2 (pt) 2021-06-22
AU2019350699B2 (en) 2024-05-23
TWI863930B (zh) 2024-12-01
US20210371368A1 (en) 2021-12-02
PE20211816A1 (es) 2021-09-14
SG11202102204PA (en) 2021-04-29
MY203278A (en) 2024-06-21
IL281761A (en) 2021-05-31
IL281761B2 (en) 2025-09-01
EP3856166A4 (en) 2022-06-22
IL281761B1 (en) 2025-05-01
CA3112205A1 (en) 2020-04-02
CL2021000728A1 (es) 2021-10-22
CO2021004529A2 (es) 2021-04-30
KR20210065120A (ko) 2021-06-03
JP7499259B2 (ja) 2024-06-13
MX2021003482A (es) 2021-06-18
AU2019350699A1 (en) 2021-04-08
TW202024013A (zh) 2020-07-01
PH12021550403A1 (en) 2021-10-04
CN112955139B (zh) 2025-04-18
CN112955139A (zh) 2021-06-11
WO2020068705A1 (en) 2020-04-02
EP3856166A1 (en) 2021-08-04

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