PE20211816A1 - Proceso de elaboracion de alfa-cetoglutarato de calcio - Google Patents
Proceso de elaboracion de alfa-cetoglutarato de calcioInfo
- Publication number
- PE20211816A1 PE20211816A1 PE2021000354A PE2021000354A PE20211816A1 PE 20211816 A1 PE20211816 A1 PE 20211816A1 PE 2021000354 A PE2021000354 A PE 2021000354A PE 2021000354 A PE2021000354 A PE 2021000354A PE 20211816 A1 PE20211816 A1 PE 20211816A1
- Authority
- PE
- Peru
- Prior art keywords
- alpha
- ketoglutarate
- salt
- calcium
- cetoglutarate
- Prior art date
Links
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 title abstract 2
- 229910052791 calcium Inorganic materials 0.000 title abstract 2
- 239000011575 calcium Substances 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title 1
- KPGXRSRHYNQIFN-UHFFFAOYSA-L 2-oxoglutarate(2-) Chemical class [O-]C(=O)CCC(=O)C([O-])=O KPGXRSRHYNQIFN-UHFFFAOYSA-L 0.000 abstract 5
- KPGXRSRHYNQIFN-UHFFFAOYSA-N 2-oxoglutaric acid Chemical compound OC(=O)CCC(=O)C(O)=O KPGXRSRHYNQIFN-UHFFFAOYSA-N 0.000 abstract 2
- 159000000007 calcium salts Chemical class 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- 102000013530 TOR Serine-Threonine Kinases Human genes 0.000 abstract 1
- 108010065917 TOR Serine-Threonine Kinases Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salt Chemical class 0.000 abstract 1
- HWXBTNAVRSUOJR-UHFFFAOYSA-N alpha-hydroxyglutaric acid Natural products OC(=O)C(O)CCC(O)=O HWXBTNAVRSUOJR-UHFFFAOYSA-N 0.000 abstract 1
- 229940009533 alpha-ketoglutaric acid Drugs 0.000 abstract 1
- 230000002715 bioenergetic effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 230000005787 mitochondrial ATP synthesis coupled electron transport Effects 0.000 abstract 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/412—Preparation of salts of carboxylic acids by conversion of the acids, their salts, esters or anhydrides with the same carboxylic acid part
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/41—Preparation of salts of carboxylic acids
- C07C51/418—Preparation of metal complexes containing carboxylic acid moieties
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/235—Saturated compounds containing more than one carboxyl group
- C07C59/347—Saturated compounds containing more than one carboxyl group containing keto groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Fodder In General (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862736320P | 2018-09-25 | 2018-09-25 | |
| PCT/US2019/052498 WO2020068705A1 (en) | 2018-09-25 | 2019-09-23 | Process of making calcium alpha-ketoglutarate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20211816A1 true PE20211816A1 (es) | 2021-09-14 |
Family
ID=69952136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2021000354A PE20211816A1 (es) | 2018-09-25 | 2019-09-23 | Proceso de elaboracion de alfa-cetoglutarato de calcio |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US11802103B2 (enExample) |
| EP (1) | EP3856166A4 (enExample) |
| JP (1) | JP7499259B2 (enExample) |
| KR (1) | KR102833111B1 (enExample) |
| CN (1) | CN112955139B (enExample) |
| AU (1) | AU2019350699B2 (enExample) |
| BR (1) | BR112021005668A2 (enExample) |
| CA (1) | CA3112205A1 (enExample) |
| CL (1) | CL2021000728A1 (enExample) |
| CO (1) | CO2021004529A2 (enExample) |
| IL (1) | IL281761B2 (enExample) |
| MX (1) | MX2021003482A (enExample) |
| MY (1) | MY203278A (enExample) |
| PE (1) | PE20211816A1 (enExample) |
| PH (1) | PH12021550403A1 (enExample) |
| SG (1) | SG11202102204PA (enExample) |
| TW (1) | TWI863930B (enExample) |
| WO (1) | WO2020068705A1 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102833111B1 (ko) | 2018-09-25 | 2025-07-10 | 폰세 드 리온 헬스 데지그네이티드 액티비티 컴퍼니 | 칼슘 알파-케토글루타레이트의 제조 방법 |
| CN112941116B (zh) * | 2021-01-04 | 2022-12-02 | 上海朴颐化学科技有限公司 | 一种酶法制备α-酮戊二酸钙的方法 |
| CN114105761B (zh) * | 2021-11-19 | 2024-06-21 | 广东派特埃尔生物科技有限公司 | 一种α-酮戊二酸钠盐的合成工艺 |
| CN115974679A (zh) * | 2022-12-20 | 2023-04-18 | 绍兴市精益生物化工有限公司 | α-酮戊二酸钙盐制备方法 |
| CN119977789A (zh) * | 2025-02-12 | 2025-05-13 | 江苏惠利生物科技有限公司 | 一种离子交换树脂制备高纯度α-酮戊二酸钙的方法 |
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| CN112941116B (zh) * | 2021-01-04 | 2022-12-02 | 上海朴颐化学科技有限公司 | 一种酶法制备α-酮戊二酸钙的方法 |
| CN115974679A (zh) * | 2022-12-20 | 2023-04-18 | 绍兴市精益生物化工有限公司 | α-酮戊二酸钙盐制备方法 |
-
2019
- 2019-09-23 KR KR1020217010402A patent/KR102833111B1/ko active Active
- 2019-09-23 JP JP2021540377A patent/JP7499259B2/ja active Active
- 2019-09-23 SG SG11202102204PA patent/SG11202102204PA/en unknown
- 2019-09-23 AU AU2019350699A patent/AU2019350699B2/en active Active
- 2019-09-23 US US17/277,752 patent/US11802103B2/en active Active
- 2019-09-23 PE PE2021000354A patent/PE20211816A1/es unknown
- 2019-09-23 MY MYPI2021001576A patent/MY203278A/en unknown
- 2019-09-23 EP EP19866432.8A patent/EP3856166A4/en active Pending
- 2019-09-23 BR BR112021005668-8A patent/BR112021005668A2/pt unknown
- 2019-09-23 CN CN201980073655.2A patent/CN112955139B/zh active Active
- 2019-09-23 MX MX2021003482A patent/MX2021003482A/es unknown
- 2019-09-23 CA CA3112205A patent/CA3112205A1/en active Pending
- 2019-09-23 WO PCT/US2019/052498 patent/WO2020068705A1/en not_active Ceased
- 2019-09-23 IL IL281761A patent/IL281761B2/en unknown
- 2019-09-25 TW TW108134655A patent/TWI863930B/zh active
-
2021
- 2021-02-26 PH PH12021550403A patent/PH12021550403A1/en unknown
- 2021-03-24 CL CL2021000728A patent/CL2021000728A1/es unknown
- 2021-04-11 CO CONC2021/0004529A patent/CO2021004529A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US11802103B2 (en) | 2023-10-31 |
| JP2022502489A (ja) | 2022-01-11 |
| BR112021005668A2 (pt) | 2021-06-22 |
| AU2019350699B2 (en) | 2024-05-23 |
| TWI863930B (zh) | 2024-12-01 |
| US20210371368A1 (en) | 2021-12-02 |
| SG11202102204PA (en) | 2021-04-29 |
| MY203278A (en) | 2024-06-21 |
| IL281761A (en) | 2021-05-31 |
| IL281761B2 (en) | 2025-09-01 |
| EP3856166A4 (en) | 2022-06-22 |
| IL281761B1 (en) | 2025-05-01 |
| CA3112205A1 (en) | 2020-04-02 |
| CL2021000728A1 (es) | 2021-10-22 |
| CO2021004529A2 (es) | 2021-04-30 |
| KR20210065120A (ko) | 2021-06-03 |
| JP7499259B2 (ja) | 2024-06-13 |
| MX2021003482A (es) | 2021-06-18 |
| AU2019350699A1 (en) | 2021-04-08 |
| TW202024013A (zh) | 2020-07-01 |
| PH12021550403A1 (en) | 2021-10-04 |
| CN112955139B (zh) | 2025-04-18 |
| CN112955139A (zh) | 2021-06-11 |
| KR102833111B1 (ko) | 2025-07-10 |
| WO2020068705A1 (en) | 2020-04-02 |
| EP3856166A1 (en) | 2021-08-04 |
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