KR102733409B1 - Rna-가이드 유전자 편집 및 유전자 조절 - Google Patents

Rna-가이드 유전자 편집 및 유전자 조절 Download PDF

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KR102733409B1
KR102733409B1 KR1020237022139A KR20237022139A KR102733409B1 KR 102733409 B1 KR102733409 B1 KR 102733409B1 KR 1020237022139 A KR1020237022139 A KR 1020237022139A KR 20237022139 A KR20237022139 A KR 20237022139A KR 102733409 B1 KR102733409 B1 KR 102733409B1
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gene
cas9
expression
protein
cells
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KR20230107387A (ko
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찰스 에이. 거스배치
아이작 비. 힐튼
파블로 페레즈-피네라
아미 엠. 카바디
프래티크샤 아이. 타코어
데이빗 쥐. 아우스터라웃
조슈아 비. 블랙
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듀크 유니버시티
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
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    • C12N9/10—Transferases (2.)
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    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/71—Fusion polypeptide containing domain for protein-protein interaction containing domain for transcriptional activaation, e.g. VP16
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    • C12N2740/00011—Details
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    • C12N2740/16011—Human Immunodeficiency Virus, HIV
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KR1020237022139A 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절 Active KR102733409B1 (ko)

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KR1020237031879A KR20230136697A (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US201361831481P 2013-06-05 2013-06-05
US61/831,481 2013-06-05
US201361839127P 2013-06-25 2013-06-25
US61/839,127 2013-06-25
US201361904911P 2013-11-15 2013-11-15
US61/904,911 2013-11-15
US201461967466P 2014-03-19 2014-03-19
US61/967,466 2014-03-19
US201461981575P 2014-04-18 2014-04-18
US61/981,575 2014-04-18
PCT/US2014/041190 WO2014197748A2 (en) 2013-06-05 2014-06-05 Rna-guided gene editing and gene regulation
KR1020217017616A KR102551324B1 (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절

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KR1020237031879A Division KR20230136697A (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절

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KR20230107387A KR20230107387A (ko) 2023-07-14
KR102733409B1 true KR102733409B1 (ko) 2024-11-21

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KR1020237022139A Active KR102733409B1 (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절
KR1020237031879A Pending KR20230136697A (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절
KR1020167000166A Active KR102307280B1 (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절
KR1020217017616A Active KR102551324B1 (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절

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KR1020237031879A Pending KR20230136697A (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절
KR1020167000166A Active KR102307280B1 (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절
KR1020217017616A Active KR102551324B1 (ko) 2013-06-05 2014-06-05 Rna-가이드 유전자 편집 및 유전자 조절

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US (4) US10704060B2 (https=)
EP (5) EP3004370B1 (https=)
JP (5) JP7085716B2 (https=)
KR (4) KR102733409B1 (https=)
CN (3) CN105658805B (https=)
AU (5) AU2014274840B2 (https=)
CA (1) CA2914519A1 (https=)
ES (3) ES2991293T3 (https=)
WO (1) WO2014197748A2 (https=)

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