KR102332790B1 - 키메라 항원 수용체 및 이의 이용 방법 - Google Patents
키메라 항원 수용체 및 이의 이용 방법 Download PDFInfo
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- KR102332790B1 KR102332790B1 KR1020207019131A KR20207019131A KR102332790B1 KR 102332790 B1 KR102332790 B1 KR 102332790B1 KR 1020207019131 A KR1020207019131 A KR 1020207019131A KR 20207019131 A KR20207019131 A KR 20207019131A KR 102332790 B1 KR102332790 B1 KR 102332790B1
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A—HUMAN NECESSITIES
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- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- C—CHEMISTRY; METALLURGY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C12N5/0634—Cells from the blood or the immune system
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C07K2319/00—Fusion polypeptide
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
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- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
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- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
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- C12N2510/00—Genetically modified cells
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- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
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- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
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- Biotechnology (AREA)
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- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020217038402A KR20210147101A (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361765585P | 2013-02-15 | 2013-02-15 | |
| US61/765,585 | 2013-02-15 | ||
| KR1020197034038A KR102132246B1 (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
| PCT/US2014/016527 WO2014127261A1 (en) | 2013-02-15 | 2014-02-14 | Chimeric antigen receptor and methods of use thereof |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020197034038A Division KR102132246B1 (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020217038402A Division KR20210147101A (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20200083682A KR20200083682A (ko) | 2020-07-08 |
| KR102332790B1 true KR102332790B1 (ko) | 2021-12-01 |
Family
ID=51354582
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020207019131A Active KR102332790B1 (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
| KR1020237003986A Active KR102813881B1 (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
| KR1020217038402A Ceased KR20210147101A (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
| KR1020157024731A Active KR102064230B1 (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
| KR1020197034038A Active KR102132246B1 (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020237003986A Active KR102813881B1 (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
| KR1020217038402A Ceased KR20210147101A (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
| KR1020157024731A Active KR102064230B1 (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
| KR1020197034038A Active KR102132246B1 (ko) | 2013-02-15 | 2014-02-14 | 키메라 항원 수용체 및 이의 이용 방법 |
Country Status (20)
| Country | Link |
|---|---|
| US (10) | US20150368342A1 (enExample) |
| EP (5) | EP2956175B1 (enExample) |
| JP (5) | JP6450690B2 (enExample) |
| KR (5) | KR102332790B1 (enExample) |
| CN (2) | CN105142677B (enExample) |
| AU (5) | AU2014216130B2 (enExample) |
| CA (1) | CA2901115A1 (enExample) |
| CY (1) | CY1122386T1 (enExample) |
| DK (2) | DK2956175T3 (enExample) |
| ES (3) | ES2758227T3 (enExample) |
| HR (1) | HRP20192123T1 (enExample) |
| HU (2) | HUE047487T2 (enExample) |
| IL (3) | IL305629A (enExample) |
| LT (2) | LT2956175T (enExample) |
| MX (2) | MX369545B (enExample) |
| NO (1) | NO2929995T3 (enExample) |
| PL (3) | PL3613439T3 (enExample) |
| PT (3) | PT3613439T (enExample) |
| SI (2) | SI3300745T1 (enExample) |
| WO (1) | WO2014127261A1 (enExample) |
Families Citing this family (330)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012088446A1 (en) | 2010-12-22 | 2012-06-28 | Board Of Trustees Of The Leland Stanford Junior University | Superagonists and antagonists of interleukin-2 |
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| WO2011119773A1 (en) | 2010-03-23 | 2011-09-29 | Roeth Jeremiah F | Vectors conditionally expressing therapeutic proteins, host cells comprising the vectors, and uses thereof |
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