KR102084561B1 - 췌장 내분비 세포로의 분화를 위한 공기-액체 계면에서의 인간 배아 줄기세포의 배양 - Google Patents
췌장 내분비 세포로의 분화를 위한 공기-액체 계면에서의 인간 배아 줄기세포의 배양 Download PDFInfo
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- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261747662P | 2012-12-31 | 2012-12-31 | |
| US61/747,662 | 2012-12-31 | ||
| PCT/US2013/075939 WO2014105543A1 (en) | 2012-12-31 | 2013-12-18 | Culturing of human embryonic stem cells at the air-liquid interface for differentiation into pancreatic endocrine cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR20150103182A KR20150103182A (ko) | 2015-09-09 |
| KR102084561B1 true KR102084561B1 (ko) | 2020-03-04 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1020157020562A Active KR102084561B1 (ko) | 2012-12-31 | 2013-12-18 | 췌장 내분비 세포로의 분화를 위한 공기-액체 계면에서의 인간 배아 줄기세포의 배양 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US10344264B2 (https=) |
| EP (1) | EP2938724B1 (https=) |
| JP (1) | JP6557146B2 (https=) |
| KR (1) | KR102084561B1 (https=) |
| CN (1) | CN105008518B (https=) |
| AR (1) | AR094347A1 (https=) |
| AU (4) | AU2013368221B2 (https=) |
| BR (1) | BR112015015770A2 (https=) |
| CA (1) | CA2896655C (https=) |
| DK (1) | DK2938724T3 (https=) |
| ES (1) | ES2837763T3 (https=) |
| HK (1) | HK1217110A1 (https=) |
| MX (1) | MX2015008577A (https=) |
| PH (1) | PH12015501465A1 (https=) |
| RU (3) | RU2658488C2 (https=) |
| SG (2) | SG11201505128SA (https=) |
| WO (1) | WO2014105543A1 (https=) |
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| DK2185693T3 (da) | 2007-07-31 | 2019-09-23 | Lifescan Inc | Differentiering af humane embryoniske stamceller |
| CA2954431C (en) | 2007-11-27 | 2021-08-24 | Lifescan, Inc. | Differentiation of human embryonic stem cells to pancreatic cells |
| CN102482643B (zh) | 2009-07-20 | 2016-06-29 | 詹森生物科技公司 | 人胚胎干细胞的分化 |
| US12441985B2 (en) | 2009-12-23 | 2025-10-14 | Janssen Biotech, Inc. | Methods for making insulin in vivo |
| FI2794857T3 (fi) | 2011-12-22 | 2026-03-25 | Janssen Biotech Inc | Ihmisen alkion kantasolujen erilaistaminen yksittäisiksi hormonaalisiksi insuliinipositiivisiksi soluiksi |
| US8859286B2 (en) * | 2013-03-14 | 2014-10-14 | Viacyte, Inc. | In vitro differentiation of pluripotent stem cells to pancreatic endoderm cells (PEC) and endocrine cells |
| CN120796168A (zh) * | 2013-06-11 | 2025-10-17 | 哈佛学院校长同事会 | SC-β细胞以及用于产生其的组合物和方法 |
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| EP3234110B1 (en) | 2014-12-18 | 2024-02-28 | President and Fellows of Harvard College | METHODS FOR GENERATING STEM CELL-DERIVED ß CELLS AND USES THEREOF |
| WO2016100898A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof |
| CN107614678B (zh) | 2014-12-18 | 2021-04-30 | 哈佛学院校长同事会 | 干细胞来源的β细胞的产生方法及其使用方法 |
| WO2016100921A1 (en) * | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | METHODS FOR GENERATING STEM CELL-DERIVED β CELLS AND USES THEREOF |
| ES3002713T3 (en) | 2016-04-08 | 2025-03-07 | Univ California | Production of fully functional mature beta cells from human pancreatic progenitors |
| KR101870240B1 (ko) * | 2016-04-12 | 2018-06-22 | 서울대학교산학협력단 | 지방줄기세포에서 신경줄기세포, 신경세포 및 가바성 신경세포로의 분화 유도 방법 |
| MD4194548T2 (ro) | 2016-06-21 | 2026-02-28 | Janssen Biotech Inc | Generarea de celule beta funcționale derivate din celule stem pluripotente umane care posedă respirație mitocondrială dependentă - de glucoză și răspuns la secreția de insulină în două faze |
| CA3032972A1 (en) * | 2016-08-19 | 2018-02-22 | Memorial Sloan-Kettering Cancer Center | Methods of differentiating stem cells into endoderm |
| KR102417262B1 (ko) * | 2016-08-24 | 2022-07-07 | 각고호우징 게이오기주크 | 인간 설사병 바이러스의 감염·증식 배양용 2d 오가노이드 및 그 사용 |
| FR3061206B1 (fr) * | 2016-12-23 | 2020-06-26 | Laboratoires Clarins | Modele de peau incluant epiderme, derme et hypoderme, son procede de preparation et son utilisation |
| US10767164B2 (en) | 2017-03-30 | 2020-09-08 | The Research Foundation For The State University Of New York | Microenvironments for self-assembly of islet organoids from stem cells differentiation |
| EP3710021A4 (en) | 2017-11-15 | 2021-08-11 | Semma Therapeutics, Inc. | ISLAND CELL MANUFACTURING COMPOSITIONS AND METHOD OF USE |
| US12421499B2 (en) | 2018-05-11 | 2025-09-23 | Cornell University | Method of differentiation of human pluripotent stem cells to monohormonal cells |
| WO2020033879A1 (en) | 2018-08-10 | 2020-02-13 | Semma Therapeutics, Inc. | Stem cell derived islet differentiation |
| US12378572B2 (en) | 2018-09-07 | 2025-08-05 | Crispr Therapeutics Ag | Universal donor cells |
| WO2020068984A1 (en) * | 2018-09-25 | 2020-04-02 | The Regents Of The University Of California | Production and enrichment of pancreatic endocrine progenitor cells |
| US20220411759A1 (en) * | 2019-05-21 | 2022-12-29 | President And Fellows Of Harvard College | Endocrine differentiation-inducing molecule |
| CN114173837A (zh) | 2019-05-31 | 2022-03-11 | W.L.戈尔及同仁股份有限公司 | 生物相容性膜复合材料 |
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| PH12022550542A1 (en) | 2019-09-05 | 2023-03-20 | Crispr Therapeutics Ag | Universal donor cells |
| CA3150235A1 (en) | 2019-09-05 | 2021-03-11 | Alireza Rezania | Universal donor cells |
| WO2022144855A1 (en) | 2020-12-31 | 2022-07-07 | Crispr Therapeutics Ag | Universal donor cells |
| CN112980774B (zh) * | 2021-03-19 | 2022-04-01 | 上海爱萨尔生物科技有限公司 | 一种诱导多能干细胞定向分化制备胰岛β细胞的培养方法 |
| CN113046299B (zh) * | 2021-03-19 | 2024-06-28 | 上海爱萨尔生物科技有限公司 | 一种诱导多能干细胞定向分化制备胰岛β细胞的添加剂 |
| CN112961823B (zh) * | 2021-03-19 | 2024-01-23 | 上海爱萨尔生物科技有限公司 | 一种诱导多能干细胞定向分化制备胰岛β细胞的培养液 |
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