MX2010002179A - Composicion para el tratamiento de enfermedades neoplasicas. - Google Patents

Composicion para el tratamiento de enfermedades neoplasicas.

Info

Publication number
MX2010002179A
MX2010002179A MX2010002179A MX2010002179A MX2010002179A MX 2010002179 A MX2010002179 A MX 2010002179A MX 2010002179 A MX2010002179 A MX 2010002179A MX 2010002179 A MX2010002179 A MX 2010002179A MX 2010002179 A MX2010002179 A MX 2010002179A
Authority
MX
Mexico
Prior art keywords
taxane
methods
administration
treatment
neoplastic disease
Prior art date
Application number
MX2010002179A
Other languages
English (en)
Inventor
Jacob Hendrik Beijnen
Johannes Henricus Matthias Schellens
Johannes Moes
Bastiaan Nuijen
Original Assignee
Stichting Het Nl Kanker I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0716591A external-priority patent/GB0716591D0/en
Application filed by Stichting Het Nl Kanker I filed Critical Stichting Het Nl Kanker I
Publication of MX2010002179A publication Critical patent/MX2010002179A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Composiciones farmac?uticas y m?todos para el tratamiento de enfermedad neopl?sica y que comprenden la combinaci?n de un taxano, tal como docetaxel, con un inhibidor de CYP3A4, tal como ritonavir. Tambi?n est?n incluidos los m?todos de tratamiento de enfermedad neopl?sica que incorpora la administraci?n de un taxano y la administraci?n un inhibidor de CYP3A4, ya sea simult?neamente o separadamente. Adem?s, se incluyen kits para llevar a cabo los m?todos. Tambi?n se incluyen composiciones farmac?uticas s?lidas con taxano para administraci?n oral que comprenden un taxano sustancialmente amorfo, un portador y un tensoactivo.
MX2010002179A 2007-08-24 2008-08-22 Composicion para el tratamiento de enfermedades neoplasicas. MX2010002179A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US95776407P 2007-08-24 2007-08-24
GB0716591A GB0716591D0 (en) 2007-08-24 2007-08-24 Composition
PCT/GB2008/002854 WO2009027644A2 (en) 2007-08-24 2008-08-22 Composition

Publications (1)

Publication Number Publication Date
MX2010002179A true MX2010002179A (es) 2010-04-27

Family

ID=39985965

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2010002179A MX2010002179A (es) 2007-08-24 2008-08-22 Composicion para el tratamiento de enfermedades neoplasicas.

Country Status (12)

Country Link
US (1) US20110207804A1 (es)
EP (1) EP2190413B1 (es)
KR (1) KR101544498B1 (es)
AR (1) AR073123A1 (es)
AU (1) AU2008291930B2 (es)
CA (1) CA2696622C (es)
CL (1) CL2009001766A1 (es)
HK (1) HK1144390A1 (es)
IL (1) IL204115B (es)
MX (1) MX2010002179A (es)
WO (1) WO2009027644A2 (es)
ZA (1) ZA201001304B (es)

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US9080145B2 (en) 2007-07-01 2015-07-14 Lifescan Corporation Single pluripotent stem cell culture
EP2185693B1 (en) 2007-07-31 2019-07-03 Lifescan, Inc. Differentiation of human embryonic stem cells
US9089544B2 (en) * 2007-08-24 2015-07-28 Slotervaart Participaties Bv Composition
EP2229434B1 (en) 2007-11-27 2011-09-07 Lifescan, Inc. Differentiation of human embryonic stem cells
CA2959401C (en) 2008-02-21 2021-12-07 Centocor Ortho Biotech Inc. Methods, surface modified plates and compositions for cell attachment, cultivation and detachment
EP2310492B1 (en) 2008-06-30 2015-07-22 Janssen Biotech, Inc. Differentiation of pluripotent stem cells
CA2742268C (en) 2008-10-31 2020-02-18 Centocor Ortho Biotech Inc. Differentiation of human embryonic stem cells to the pancreatic endocrine lineage
US9012218B2 (en) 2008-10-31 2015-04-21 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
AU2009316583B2 (en) 2008-11-20 2016-04-21 Janssen Biotech, Inc. Methods and compositions for cell attachment and cultivation on planar substrates
RU2555538C2 (ru) 2008-11-20 2015-07-10 Сентокор Орто Байотек Инк. Культура плюрипотентных стволовых клеток на микроносителях
BR112012001480A2 (pt) 2009-07-20 2015-09-01 Janssen Biotech Inc Diferenciação de células-tronco embriônicas humanas
CN102482640B (zh) 2009-07-20 2015-03-11 詹森生物科技公司 人胚胎干细胞的分化
GB2485113B (en) 2009-07-20 2016-12-28 Janssen Biotech Inc Differentiation of human embryonic stem cells into cells of the pancreatic endoderm lineage
ES2624644T3 (es) * 2009-10-01 2017-07-17 Janssen Pharmaceutica, N.V. Inhibidores de proteasoma para el tratamiento de cáncer
RU2664864C1 (ru) 2009-12-23 2018-08-23 Янссен Байотек, Инк. Способы увеличения экспрессии ngn3 и nkx6.1 в эндокринных клетках поджелудочной железы
US9150833B2 (en) 2009-12-23 2015-10-06 Janssen Biotech, Inc. Differentiation of human embryonic stem cells
WO2011086194A1 (en) * 2010-01-18 2011-07-21 Cephalon France Improved oral lysophilisates containing pvp/va
WO2011109279A2 (en) 2010-03-01 2011-09-09 Centocor Ortho Biotech Inc. Methods for purifying cells derived from pluripotent stem cells
CN102884176B (zh) 2010-05-12 2017-09-05 詹森生物科技公司 人胚胎干细胞的分化
PL2611910T3 (pl) 2010-08-31 2018-06-29 Janssen Biotech, Inc Różnicowanie ludzkich embrionalnych komórek macierzystych
RU2673946C1 (ru) 2010-08-31 2018-12-03 Янссен Байотек, Инк. Дифференцирование плюрипотентных стволовых клеток
PL2611909T3 (pl) 2010-08-31 2018-05-30 Janssen Biotech, Inc Zróżnicowanie ludzkich embrionalnych komórek macierzystych
BR112014015417A8 (pt) 2011-12-22 2017-07-04 Janssen Biotech Inc diferenciação de células-tronco embrionárias humanas em células positivas de insulina hormonal únicas
AU2013230020B2 (en) 2012-03-07 2018-08-09 Janssen Biotech, Inc. Defined media for expansion and maintenance of pluripotent stem cells
CN104334719B (zh) 2012-06-08 2018-02-13 詹森生物科技公司 人胚胎干细胞向胰腺内分泌细胞的分化
US9352047B2 (en) 2012-11-14 2016-05-31 Abon Pharmaceuticals, Llc Oral transmucosal drug delivery system
MX2015008578A (es) 2012-12-31 2015-09-07 Janssen Biotech Inc Diferenciacion de celulas madre embrionarias humanas en celulas endocrinas pancreaticas mediante el uso de relugadores de hb9.
US10370644B2 (en) 2012-12-31 2019-08-06 Janssen Biotech, Inc. Method for making human pluripotent suspension cultures and cells derived therefrom
RU2018116647A (ru) 2012-12-31 2018-10-24 Янссен Байотек, Инк. Культивация эмбриональных стволовых клеток человека в воздушно-жидкостной зоне взаимодействия с целью их дифференцировки в панкреатические эндокринные клетки
MX2015008619A (es) 2012-12-31 2016-01-12 Janssen Biotech Inc Suspension y agrupamiento de celulas humanas pluripotentes para la diferenciacion a celulas endocrinas pancreaticas.
WO2015152433A1 (en) * 2014-03-31 2015-10-08 Hanmi Pharm. Co., Ltd. Amorphous solid dispersion comprising paclitaxel, tablet comprising the same, and method for preparing the same
RU2694311C2 (ru) 2014-05-16 2019-07-11 Янссен Байотек, Инк. Применение малых молекул для увеличения экспрессии mafa в панкреатических эндокринных клетках
MA45479A (fr) 2016-04-14 2019-02-20 Janssen Biotech Inc Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
KR20220002860A (ko) 2018-12-21 2022-01-07 모드라 파마슈티컬스 비.브이. 피크 혈장 수준의 제어에 의한 도세탁셀을 사용하는 암 치료
EP3897611A1 (en) * 2018-12-21 2021-10-27 Modra Pharmaceuticals B.V. Combination treatment for solid tumors using docetaxel and a cyp3a inhibitor
GB202201935D0 (en) 2022-02-14 2022-03-30 Modra Pharmaceuticals B V Methods and compositions for treating cancer in taxane-resistant patients
WO2023171894A1 (ko) * 2022-03-08 2023-09-14 주식회사 위바이오트리 도세탁셀 또는 이의 약학적으로 허용 가능한 염을 포함하는 약학적 조성물 및 이의 제조방법
KR20240003032A (ko) 2022-06-29 2024-01-08 주식회사 나노메디팜 다중 작용 기전을 가지는 초미립 크기의 항암 약물이 탑재된 나노 약물전달 플랫폼, 이를 포함하는 약제학적 조성물 및 그 제조 방법
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Also Published As

Publication number Publication date
EP2190413A2 (en) 2010-06-02
AU2008291930A1 (en) 2009-03-05
AU2008291930B2 (en) 2014-04-17
ZA201001304B (en) 2013-08-28
WO2009027644A3 (en) 2009-12-17
EP2190413B1 (en) 2015-01-28
CA2696622A1 (en) 2009-03-05
KR20100044237A (ko) 2010-04-29
CL2009001766A1 (es) 2010-07-09
IL204115B (en) 2019-05-30
CA2696622C (en) 2016-07-19
US20110207804A1 (en) 2011-08-25
AR073123A1 (es) 2010-10-13
HK1144390A1 (en) 2011-02-18
WO2009027644A2 (en) 2009-03-05
WO2009027644A8 (en) 2009-04-30
KR101544498B1 (ko) 2015-08-17

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