KR102059545B1 - 키나제 억제제로서의 비아릴 아미드 화합물 - Google Patents

키나제 억제제로서의 비아릴 아미드 화합물 Download PDF

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KR102059545B1
KR102059545B1 KR1020157028099A KR20157028099A KR102059545B1 KR 102059545 B1 KR102059545 B1 KR 102059545B1 KR 1020157028099 A KR1020157028099 A KR 1020157028099A KR 20157028099 A KR20157028099 A KR 20157028099A KR 102059545 B1 KR102059545 B1 KR 102059545B1
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methyl
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KR20150133214A (ko
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로버트 아베르사
폴 에이. 바산티
매튜 버거
마이클 패트릭 딜런
알랜 디페사
쳉 후
얀 로우
지젤 니시구치
위에 판
발레리 폴랴코브
사비트리 라머시
앨리스 리코
리나 세티
아론 스미스
사라드하 수브라마니안
벤자민 타프트
휴 태너
리펭 완
나임 유서프
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노파르티스 아게
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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    • A61K31/50—Pyridazines; Hydrogenated pyridazines
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