KR101328273B1 - 세포 증식 질환의 치료를 위한 조성물 및 방법 - Google Patents
세포 증식 질환의 치료를 위한 조성물 및 방법 Download PDFInfo
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- KR101328273B1 KR101328273B1 KR1020077017102A KR20077017102A KR101328273B1 KR 101328273 B1 KR101328273 B1 KR 101328273B1 KR 1020077017102 A KR1020077017102 A KR 1020077017102A KR 20077017102 A KR20077017102 A KR 20077017102A KR 101328273 B1 KR101328273 B1 KR 101328273B1
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- 0 Cc(nc(CC(NCc1nc(*)nc(*)c1)=O)cc1)c1-c1c(*)cc(*=C)cc1 Chemical compound Cc(nc(CC(NCc1nc(*)nc(*)c1)=O)cc1)c1-c1c(*)cc(*=C)cc1 0.000 description 17
- JXNAIOCJWBJGFQ-UHFFFAOYSA-N Cc(nc1)ccc1-c1ccccc1 Chemical compound Cc(nc1)ccc1-c1ccccc1 JXNAIOCJWBJGFQ-UHFFFAOYSA-N 0.000 description 1
- FUZDNUCSQVIABE-UHFFFAOYSA-N Cc(nc1)ccc1OS(C(F)(F)F)(=C)=O Chemical compound Cc(nc1)ccc1OS(C(F)(F)F)(=C)=O FUZDNUCSQVIABE-UHFFFAOYSA-N 0.000 description 1
- MOHPGQJPGFGHQI-UHFFFAOYSA-O O=C(Cc([nH+]c1)ccc1-c1ccccc1)NCc1cc(F)ccc1 Chemical compound O=C(Cc([nH+]c1)ccc1-c1ccccc1)NCc1cc(F)ccc1 MOHPGQJPGFGHQI-UHFFFAOYSA-O 0.000 description 1
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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| US63983404P | 2004-12-28 | 2004-12-28 | |
| US60/639,834 | 2004-12-28 | ||
| US70455105P | 2005-08-01 | 2005-08-01 | |
| US60/704,551 | 2005-08-01 | ||
| US72734105P | 2005-10-17 | 2005-10-17 | |
| US60/727,341 | 2005-10-17 | ||
| PCT/US2005/047333 WO2006071960A2 (en) | 2004-12-28 | 2005-12-28 | Compositions and methods of treating cell proliferation disorders |
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| KR1020137015670A Expired - Lifetime KR101478933B1 (ko) | 2004-12-28 | 2005-12-28 | 세포 증식 질환의 치료를 위한 조성물 및 방법 |
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| WO2018031988A1 (en) * | 2016-08-12 | 2018-02-15 | Athenex, Inc. | Biaryl compositions and methods for modulating a kinase cascade |
| US10213435B2 (en) | 2016-08-12 | 2019-02-26 | Athenex, Inc. | Biaryl compositions and methods for modulating a kinase cascade |
| US10973828B2 (en) | 2016-08-12 | 2021-04-13 | Athenex, Inc. | Biaryl compositions and methods for modulating a kinase cascade |
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