ATE552253T1 - 3-substituierte-6-aryl- pyridin derivate als liganden für c5a-rezeptoren - Google Patents

3-substituierte-6-aryl- pyridin derivate als liganden für c5a-rezeptoren

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Publication number
ATE552253T1
ATE552253T1 AT03768799T AT03768799T ATE552253T1 AT E552253 T1 ATE552253 T1 AT E552253T1 AT 03768799 T AT03768799 T AT 03768799T AT 03768799 T AT03768799 T AT 03768799T AT E552253 T1 ATE552253 T1 AT E552253T1
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Austria
Prior art keywords
receptors
substituted
compounds
aryl
ligands
Prior art date
Application number
AT03768799T
Other languages
English (en)
Inventor
Alan Hutchison
Jun Yuan
Kyungae Lee
George Maynard
Bertrand Chenard
Nian Liu
Qin Guo
Zihong Guo
Peter Hrnciar
Original Assignee
Novartis Int Pharm Ltd
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Publication of ATE552253T1 publication Critical patent/ATE552253T1/de

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    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
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    • A61P17/00—Drugs for dermatological disorders
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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AT03768799T 2002-11-08 2003-11-07 3-substituierte-6-aryl- pyridin derivate als liganden für c5a-rezeptoren ATE552253T1 (de)

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AU2003291403A1 (en) 2004-06-03
US20110281837A1 (en) 2011-11-17
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WO2004043925A3 (en) 2004-08-05
US7342115B2 (en) 2008-03-11
US20040158067A1 (en) 2004-08-12
US7863454B2 (en) 2011-01-04
CA2504941A1 (en) 2004-05-27
AU2003291403A8 (en) 2004-06-03
EP1565452B1 (de) 2012-04-04
CA2504941C (en) 2012-06-26
EP1565452A2 (de) 2005-08-24

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