KR100620148B1 - 잔토실룸 번지아눔의 추출물 및 이들을 함유한 약제와화장품 조성물 - Google Patents
잔토실룸 번지아눔의 추출물 및 이들을 함유한 약제와화장품 조성물 Download PDFInfo
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- KR100620148B1 KR100620148B1 KR1020017000047A KR20017000047A KR100620148B1 KR 100620148 B1 KR100620148 B1 KR 100620148B1 KR 1020017000047 A KR1020017000047 A KR 1020017000047A KR 20017000047 A KR20017000047 A KR 20017000047A KR 100620148 B1 KR100620148 B1 KR 100620148B1
- Authority
- KR
- South Korea
- Prior art keywords
- extract
- extracts
- zanthoxylum bungeanum
- pharmaceutical
- analgesic
- Prior art date
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- 239000000284 extract Substances 0.000 title claims abstract description 44
- 241000032846 Zanthoxylum bungeanum Species 0.000 title claims abstract 4
- 239000000203 mixture Substances 0.000 title claims description 6
- 239000002537 cosmetic Substances 0.000 title claims description 5
- 238000009472 formulation Methods 0.000 title description 3
- 230000000202 analgesic effect Effects 0.000 claims abstract description 8
- KDSNLYIMUZNERS-UHFFFAOYSA-N 2-methylpropanamine Chemical class CC(C)CN KDSNLYIMUZNERS-UHFFFAOYSA-N 0.000 claims description 3
- 230000001139 anti-pruritic effect Effects 0.000 claims description 3
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- 239000004480 active ingredient Substances 0.000 claims 2
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- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
- 244000089698 Zanthoxylum simulans Species 0.000 description 8
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- 229940100555 2-methyl-4-isothiazolin-3-one Drugs 0.000 description 1
- 229940100484 5-chloro-2-methyl-4-isothiazolin-3-one Drugs 0.000 description 1
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- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 description 1
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- 241000700159 Rattus Species 0.000 description 1
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- ZCTXEAQXZGPWFG-UHFFFAOYSA-N imidurea Chemical compound O=C1NC(=O)N(CO)C1NC(=O)NCNC(=O)NC1C(=O)NC(=O)N1CO ZCTXEAQXZGPWFG-UHFFFAOYSA-N 0.000 description 1
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- 125000000913 palmityl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
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Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/758—Zanthoxylum, e.g. pricklyash
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Abstract
Description
처치 | To분 | T30분 |
대조군 | 45.7±1.0 | 45.3±0.4 |
본 발명의 추출물 | 46.0±0.8 | 47.2±0.4 |
시간 (분) | 수분 (%) | 아세토니트릴 (%) | 경사곡선의 수 (No. of Gradientcurve) |
0 | 60 | 40 | - |
20 | 60 | 40 | 6 |
30 | 10 | 90 | 6 |
35 | 60 | 40 | 6 |
40 | 60 | 40 | 6 |
Claims (5)
- 잔토실룸 번지아눔(Zanthoxylum bungeanum) 과피를 35 내지 55 ℃의 온도범위에서 150 내지 300 바의 압력범위하에 초임계 조건하 CO2로 추출하여 얻어지는, 이소부틸 아마이드류 (isobutyl amides)를 20 내지 50 중량% 범위로 포함된, 진통작용과 항소양작용을 갖는 잔토실룸 번지아눔 추출물.
- 삭제
- 삭제
- 유효성분으로 제1항의 추출물과 부형제로 구성된 진통작용과 항소양작용을 갖는 약제학적 조성물.
- 유효성분으로 제1항의 추출물과 부형제로 구성된 화장품 조성물.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT98MI001542A ITMI981542A1 (it) | 1998-07-07 | 1998-07-07 | Estratti di zanthoxylum bungeanum e loro formulazioni farmaceutiche e cosmetiche |
ITMI98A001542 | 1998-07-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
KR20010053374A KR20010053374A (ko) | 2001-06-25 |
KR100620148B1 true KR100620148B1 (ko) | 2006-09-05 |
Family
ID=11380385
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR1020017000047A KR100620148B1 (ko) | 1998-07-07 | 1999-04-07 | 잔토실룸 번지아눔의 추출물 및 이들을 함유한 약제와화장품 조성물 |
Country Status (21)
Country | Link |
---|---|
US (1) | US6419950B2 (ko) |
EP (1) | EP1096944B1 (ko) |
JP (1) | JP4776776B2 (ko) |
KR (1) | KR100620148B1 (ko) |
CN (1) | CN1308541A (ko) |
AT (1) | ATE213949T1 (ko) |
AU (1) | AU749947B2 (ko) |
CA (1) | CA2336542C (ko) |
CZ (1) | CZ292523B6 (ko) |
DE (1) | DE69900999T2 (ko) |
DK (1) | DK1096944T3 (ko) |
ES (1) | ES2173732T3 (ko) |
HU (1) | HU228795B1 (ko) |
IL (2) | IL140702A0 (ko) |
IT (1) | ITMI981542A1 (ko) |
NO (1) | NO325091B1 (ko) |
PL (1) | PL191160B1 (ko) |
PT (1) | PT1096944E (ko) |
RU (1) | RU2214817C2 (ko) |
SK (1) | SK284804B6 (ko) |
WO (1) | WO2000002570A1 (ko) |
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FR2807317B1 (fr) * | 2000-04-10 | 2002-08-16 | Indena Sa | Compositions de soin capillaire |
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JP2003321315A (ja) * | 2002-04-24 | 2003-11-11 | Hiromi Nishii | 植物エキス配合液剤 |
US20040013723A1 (en) * | 2002-07-16 | 2004-01-22 | PARIKH Rita M. | Oral care capsules |
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ITMI20032286A1 (it) * | 2003-11-24 | 2005-05-25 | Indena Spa | Composizioni per il trattamento di dermatiti atopiche di stati allergici cutanei e dell'acne |
US7087497B2 (en) * | 2004-03-04 | 2006-08-08 | Applied Materials | Low-thermal-budget gapfill process |
ITMI20042414A1 (it) | 2004-12-17 | 2005-03-17 | Indena Spa | Formulazione per il trattamento di affezioni delle prime vie respiratorie |
EP1882473A1 (en) | 2006-07-28 | 2008-01-30 | Indena S.P.A. | Use of anthocyanosides to prepare formulations for the treatment of mucositis induced by antitumoral drugs |
FR2905854B1 (fr) * | 2006-09-15 | 2010-07-30 | Fabre Pierre Dermo Cosmetique | Composition a base de xanthoxyline et son utilisation en cosmetique |
ITMI20071136A1 (it) | 2007-06-04 | 2008-12-05 | Velleja Res Srl | Formulazioni topiche per la prevenzione e il trattamento degli stati infiammatori e/o infettivi dell'aera genitale |
ITMI20080395A1 (it) * | 2008-03-10 | 2009-09-11 | Indena Spa | Formulazioni per il trattamento delle verruche e delle placche psoriatiche |
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US20130108717A1 (en) | 2010-05-18 | 2013-05-02 | Indena S.P.A. | Compositions for the treatment of gynaecological disorders |
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JP5628135B2 (ja) * | 2011-11-14 | 2014-11-19 | 長谷川香料株式会社 | ヒドロキシサンショオール含有物の製造方法 |
US20140120190A1 (en) * | 2012-10-20 | 2014-05-01 | Dong-Qing WEI | Methods of preparing prickly-ash peel extracts and cosmetic compositions incorporating prickly-ash peel extracts |
ITMI20130807A1 (it) * | 2013-05-16 | 2014-11-17 | Indena Spa | Combinazioni di estratti di serenoa repens e di estratti lipofili di zingiber officinalis e di echinacea angustifolia, loro uso e formulazioni che li contengono |
DE102013213596A1 (de) | 2013-07-11 | 2015-01-15 | Henkel Ag & Co. Kgaa | Mund- und Zahnpflege- und -reinigungsmittel zur Zahnfleischvitalisierung |
ITLE20130014A1 (it) * | 2013-09-26 | 2015-03-27 | Ekuberg Pharma Srl | Composizione per crema lenitiva |
RU2677894C2 (ru) * | 2014-02-20 | 2019-01-22 | Индена С.П.А. | Композиции, содержащие экстракты Curcuma Longa и Echinacea angustifolia, которые являются полезными для уменьшения периферического воспаления и боли |
CN104784317B (zh) * | 2015-05-08 | 2017-10-31 | 李会杰 | 椒目中植物化学素的分离方法 |
ES2610208B1 (es) * | 2015-10-22 | 2018-02-07 | Innovativehealth Group, S.L. | Formulación cosmética de uso tópico para el cuidado de la piel atópica |
ITUB20156036A1 (it) | 2015-11-30 | 2017-05-30 | Indena Spa | Estratti di echinacea angustifolia e zanthoxylum bungeanum per la prevenzione e/o il trattamento dell?obesita e del sovrappeso |
ITUB20161030A1 (it) * | 2016-02-24 | 2017-08-24 | Indena Spa | Composizioni utili nella prevenzione e/o nel trattamento dell’infiammazione e del dolore |
ITUA20164757A1 (it) | 2016-06-29 | 2017-12-29 | Indena Spa | Composizioni utili nella prevenzione e/o nel trattamento dell’infiammazione e del dolore osteoarticolare e del danno cartilagineo |
EP3335716A1 (en) * | 2016-12-15 | 2018-06-20 | Indena S.p.A. | Process for the preparation of powder compositions |
CN107141231B (zh) * | 2017-04-11 | 2019-08-27 | 双柏一禾农业科技有限公司 | 高纯度花椒麻素的制备方法 |
CN109718297A (zh) * | 2018-08-06 | 2019-05-07 | 四川省中医药科学院 | 一种花椒提取物和辣椒碱的药物组合物 |
JP6630880B1 (ja) * | 2018-08-23 | 2020-01-15 | 山本 芳栄 | サンショオール類の安定化方法 |
CN112293500B (zh) * | 2019-07-26 | 2023-03-31 | 成都大学 | 一种花椒籽油干粉的制备方法 |
JP7433125B2 (ja) | 2020-04-17 | 2024-02-19 | オリザ油化株式会社 | 口腔用抗菌剤 |
CN111568794B (zh) * | 2020-06-17 | 2021-05-18 | 上海交通大学 | 花椒提取物中活性成分wgx50的新用途 |
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JPH09255583A (ja) * | 1996-03-25 | 1997-09-30 | Yamamoto Koryo Kk | 抗かゆみ剤 |
FR2754452B1 (fr) * | 1996-10-11 | 2003-02-14 | Oreal | Emulsion h/e a forte teneur en electrolytes et leur utilisation en dermo-cosmetique, notamment pour traiter les phenomenes d'irritation et/ou de peaux sensibles |
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- 1999-04-07 RU RU2001101448/14A patent/RU2214817C2/ru active
- 1999-04-07 AT AT99915744T patent/ATE213949T1/de active
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KR930000357B1 (ko) * | 1987-03-20 | 1993-01-16 | 세이데쓰 가가꾸 고오교 가부시끼가이샤 | 식용 조성물의 제조방법 |
Also Published As
Publication number | Publication date |
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ATE213949T1 (de) | 2002-03-15 |
HUP0104923A2 (hu) | 2002-05-29 |
RU2214817C2 (ru) | 2003-10-27 |
AU749947B2 (en) | 2002-07-04 |
IL140702A (en) | 2006-10-31 |
DE69900999D1 (de) | 2002-04-11 |
DK1096944T3 (da) | 2002-06-17 |
IL140702A0 (en) | 2002-02-10 |
NO20010033D0 (no) | 2001-01-03 |
JP2002520289A (ja) | 2002-07-09 |
AU3420699A (en) | 2000-02-01 |
SK72001A3 (en) | 2001-09-11 |
CZ200121A3 (cs) | 2001-07-11 |
EP1096944A1 (en) | 2001-05-09 |
EP1096944B1 (en) | 2002-03-06 |
PT1096944E (pt) | 2002-07-31 |
HUP0104923A3 (en) | 2002-07-29 |
PL191160B1 (pl) | 2006-03-31 |
ITMI981542A1 (it) | 2000-01-07 |
CZ292523B6 (cs) | 2003-10-15 |
HU228795B1 (en) | 2013-05-28 |
NO325091B1 (no) | 2008-01-28 |
SK284804B6 (sk) | 2005-11-03 |
CA2336542A1 (en) | 2000-01-20 |
PL345262A1 (en) | 2001-12-03 |
KR20010053374A (ko) | 2001-06-25 |
JP4776776B2 (ja) | 2011-09-21 |
US20010002260A1 (en) | 2001-05-31 |
US6419950B2 (en) | 2002-07-16 |
CA2336542C (en) | 2010-10-12 |
ES2173732T3 (es) | 2002-10-16 |
DE69900999T2 (de) | 2003-02-06 |
CN1308541A (zh) | 2001-08-15 |
WO2000002570A1 (en) | 2000-01-20 |
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