KR100568482B1 - 약학적 히드로겔 제형, 약물 운반 장치 및 방법 - Google Patents

약학적 히드로겔 제형, 약물 운반 장치 및 방법 Download PDF

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Publication number
KR100568482B1
KR100568482B1 KR1020007006165A KR20007006165A KR100568482B1 KR 100568482 B1 KR100568482 B1 KR 100568482B1 KR 1020007006165 A KR1020007006165 A KR 1020007006165A KR 20007006165 A KR20007006165 A KR 20007006165A KR 100568482 B1 KR100568482 B1 KR 100568482B1
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South Korea
Prior art keywords
hydrogel
drug
formulation
polyvinyl alcohol
pharmaceutical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
KR1020007006165A
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English (en)
Korean (ko)
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KR20010032839A (ko
Inventor
멀독토마스오.
푸드지잔토스테파너스
벤카트라맨서브라마니안에스.
Original Assignee
알자 코포레이션
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Publication of KR20010032839A publication Critical patent/KR20010032839A/ko
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Publication of KR100568482B1 publication Critical patent/KR100568482B1/ko
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
KR1020007006165A 1997-12-09 1998-12-01 약학적 히드로겔 제형, 약물 운반 장치 및 방법 Expired - Fee Related KR100568482B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/987,372 US6039977A (en) 1997-12-09 1997-12-09 Pharmaceutical hydrogel formulations, and associated drug delivery devices and methods
US08/987,372 1997-12-09
US8/987,372 1997-12-09
PCT/US1998/025120 WO1999029348A1 (en) 1997-12-09 1998-12-01 Pharmaceutical hydrogel formulations, drug delivery devices and methods

Publications (2)

Publication Number Publication Date
KR20010032839A KR20010032839A (ko) 2001-04-25
KR100568482B1 true KR100568482B1 (ko) 2006-04-07

Family

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Family Applications (1)

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KR1020007006165A Expired - Fee Related KR100568482B1 (ko) 1997-12-09 1998-12-01 약학적 히드로겔 제형, 약물 운반 장치 및 방법

Country Status (16)

Country Link
US (1) US6039977A (enExample)
EP (1) EP1037667B1 (enExample)
JP (1) JP2001525377A (enExample)
KR (1) KR100568482B1 (enExample)
CN (1) CN1147319C (enExample)
AR (1) AR017197A1 (enExample)
AT (1) ATE266422T1 (enExample)
AU (1) AU1535799A (enExample)
CA (1) CA2313642C (enExample)
DE (1) DE69823869T2 (enExample)
DK (1) DK1037667T3 (enExample)
ES (1) ES2221228T3 (enExample)
PT (1) PT1037667E (enExample)
TW (1) TWI231214B (enExample)
WO (1) WO1999029348A1 (enExample)
ZA (1) ZA9810641B (enExample)

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DE60231862D1 (de) * 2001-02-23 2009-05-20 Genentech Inc Erodierbare polymere zur injektion
CA2443326A1 (en) * 2001-04-04 2002-10-17 Alza Corporation Transdermal electrotransport delivery device including an antimicrobial compatible reservoir composition
PT1397155E (pt) * 2001-06-21 2015-12-07 Genentech Inc Formulação de libertação sustentada
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
ITMI20012060A1 (it) * 2001-10-05 2003-04-05 Recordati Chem Pharm Nuovi eterocilcli n-acilati
AU2002351164A1 (en) * 2001-11-26 2003-06-10 Molecular Reflections, Inc. Microscale immobilization of molecules using a hydrogel and methods of use thereof
WO2004002571A1 (en) 2002-06-28 2004-01-08 Alza Corporation A reservoir for use in an electrotransport drug delivery device
US20040158194A1 (en) * 2003-02-06 2004-08-12 Wolff Andy And Beiski Ben Z. Oral devices and methods for controlled drug release
US20050142531A1 (en) * 2003-11-19 2005-06-30 David Rauser Peptidically buffered formulations for electrotransport applications and methods of making
CN1921829B (zh) * 2003-12-05 2010-05-05 纳米比亚医学调查研究有限公司 贴片
CN100386073C (zh) * 2004-03-03 2008-05-07 杭州民生药业集团有限公司 一种经皮给药系统
US7491263B2 (en) * 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
US20060135906A1 (en) * 2004-11-16 2006-06-22 Akihiko Matsumura Iontophoretic device and method for administering immune response-enhancing agents and compositions
US20070106138A1 (en) * 2005-05-26 2007-05-10 Beiski Ben Z Intraoral apparatus for non-invasive blood and saliva monitoring & sensing
US20090143761A1 (en) * 2005-06-03 2009-06-04 Transdermal Patents Company, Llc Agent delivery system and uses of same
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RU2008112156A (ru) 2005-08-31 2009-10-10 Алза Корпорейшн (Us) Катод для осуществления электропереноса анионного медикамента
WO2007041322A2 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoretic delivery of active agents conjugated to nanoparticles
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WO2007109274A2 (en) * 2006-03-21 2007-09-27 Alza Corporation Hydratable polymeric ester matrix for drug electrotransport
US8246973B2 (en) * 2006-06-21 2012-08-21 Advanced Cardiovascular Systems, Inc. Freeze-thaw method for modifying stent coating
JP2010502270A (ja) * 2006-08-29 2010-01-28 アルザ・コーポレーシヨン 水和可能な貯蔵器の水和測定付きの薬品電気輸送
US7538652B2 (en) * 2006-08-29 2009-05-26 International Business Machines Corporation Electrical component tuned by conductive layer deletion
US20080193514A1 (en) * 2006-11-02 2008-08-14 Transcu Ltd. Compostions and methods for iontophoresis delivery of active ingredients through hair follicles
EP2101864A2 (en) * 2006-12-20 2009-09-23 ALZA Corporation Anode for electrotransport of cationic drug
WO2008087803A1 (ja) * 2007-01-16 2008-07-24 Hokkaido University 抗酸化成分を封入したイオントフォレーシス用リポソーム製剤
US20080234627A1 (en) * 2007-03-22 2008-09-25 Wanda Dent Pivotally engaged multiple part electrotransport drug delivery device
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Also Published As

Publication number Publication date
DE69823869T2 (de) 2005-05-19
KR20010032839A (ko) 2001-04-25
EP1037667B1 (en) 2004-05-12
US6039977A (en) 2000-03-21
CA2313642C (en) 2008-09-30
JP2001525377A (ja) 2001-12-11
CN1147319C (zh) 2004-04-28
WO1999029348A1 (en) 1999-06-17
EP1037667A1 (en) 2000-09-27
AR017197A1 (es) 2001-08-22
AU1535799A (en) 1999-06-28
CN1281372A (zh) 2001-01-24
ES2221228T3 (es) 2004-12-16
ATE266422T1 (de) 2004-05-15
PT1037667E (pt) 2004-08-31
TWI231214B (en) 2005-04-21
ZA9810641B (en) 1999-05-24
DK1037667T3 (da) 2004-09-20
DE69823869D1 (de) 2004-06-17
CA2313642A1 (en) 1999-06-17

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St.27 status event code: A-4-4-U10-U13-oth-PC1903

Not in force date: 20110401

Payment event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

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St.27 status event code: N-4-6-H10-H13-oth-PC1903

Ip right cessation event data comment text: Termination Category : DEFAULT_OF_REGISTRATION_FEE

Not in force date: 20110401