CA2313642C - Pharmaceutical hydrogel formulations, drug delivery devices and methods - Google Patents
Pharmaceutical hydrogel formulations, drug delivery devices and methods Download PDFInfo
- Publication number
- CA2313642C CA2313642C CA002313642A CA2313642A CA2313642C CA 2313642 C CA2313642 C CA 2313642C CA 002313642 A CA002313642 A CA 002313642A CA 2313642 A CA2313642 A CA 2313642A CA 2313642 C CA2313642 C CA 2313642C
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- hydrogel
- polyvinyl alcohol
- formulation
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Classifications
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61P13/00—Drugs for disorders of the urinary system
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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Landscapes
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- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Inorganic Chemistry (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/987,372 US6039977A (en) | 1997-12-09 | 1997-12-09 | Pharmaceutical hydrogel formulations, and associated drug delivery devices and methods |
| US08/987,372 | 1997-12-09 | ||
| PCT/US1998/025120 WO1999029348A1 (en) | 1997-12-09 | 1998-12-01 | Pharmaceutical hydrogel formulations, drug delivery devices and methods |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2313642A1 CA2313642A1 (en) | 1999-06-17 |
| CA2313642C true CA2313642C (en) | 2008-09-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002313642A Expired - Fee Related CA2313642C (en) | 1997-12-09 | 1998-12-01 | Pharmaceutical hydrogel formulations, drug delivery devices and methods |
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|---|---|
| US (1) | US6039977A (enExample) |
| EP (1) | EP1037667B1 (enExample) |
| JP (1) | JP2001525377A (enExample) |
| KR (1) | KR100568482B1 (enExample) |
| CN (1) | CN1147319C (enExample) |
| AR (1) | AR017197A1 (enExample) |
| AT (1) | ATE266422T1 (enExample) |
| AU (1) | AU1535799A (enExample) |
| CA (1) | CA2313642C (enExample) |
| DE (1) | DE69823869T2 (enExample) |
| DK (1) | DK1037667T3 (enExample) |
| ES (1) | ES2221228T3 (enExample) |
| PT (1) | PT1037667E (enExample) |
| TW (1) | TWI231214B (enExample) |
| WO (1) | WO1999029348A1 (enExample) |
| ZA (1) | ZA9810641B (enExample) |
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| US6440457B1 (en) * | 1993-05-27 | 2002-08-27 | Alza Corporation | Method of administering antidepressant dosage form |
| GB0005016D0 (en) * | 2000-03-01 | 2000-04-26 | Jumik Technologies Limited | PVA-Containing compositions |
| JP4361710B2 (ja) | 2000-04-19 | 2009-11-11 | ジェネンテック・インコーポレーテッド | 徐放製剤 |
| KR100452972B1 (ko) * | 2000-05-16 | 2004-10-14 | 주식회사 삼양사 | 경피투여용 하이드로젤 조성물 |
| DE60231862D1 (de) * | 2001-02-23 | 2009-05-20 | Genentech Inc | Erodierbare polymere zur injektion |
| CA2443326A1 (en) * | 2001-04-04 | 2002-10-17 | Alza Corporation | Transdermal electrotransport delivery device including an antimicrobial compatible reservoir composition |
| PT1397155E (pt) * | 2001-06-21 | 2015-12-07 | Genentech Inc | Formulação de libertação sustentada |
| DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
| ITMI20012060A1 (it) * | 2001-10-05 | 2003-04-05 | Recordati Chem Pharm | Nuovi eterocilcli n-acilati |
| AU2002351164A1 (en) * | 2001-11-26 | 2003-06-10 | Molecular Reflections, Inc. | Microscale immobilization of molecules using a hydrogel and methods of use thereof |
| WO2004002571A1 (en) | 2002-06-28 | 2004-01-08 | Alza Corporation | A reservoir for use in an electrotransport drug delivery device |
| US20040158194A1 (en) * | 2003-02-06 | 2004-08-12 | Wolff Andy And Beiski Ben Z. | Oral devices and methods for controlled drug release |
| US20050142531A1 (en) * | 2003-11-19 | 2005-06-30 | David Rauser | Peptidically buffered formulations for electrotransport applications and methods of making |
| CN1921829B (zh) * | 2003-12-05 | 2010-05-05 | 纳米比亚医学调查研究有限公司 | 贴片 |
| CN100386073C (zh) * | 2004-03-03 | 2008-05-07 | 杭州民生药业集团有限公司 | 一种经皮给药系统 |
| US7491263B2 (en) * | 2004-04-05 | 2009-02-17 | Technology Innovation, Llc | Storage assembly |
| US20060135906A1 (en) * | 2004-11-16 | 2006-06-22 | Akihiko Matsumura | Iontophoretic device and method for administering immune response-enhancing agents and compositions |
| US20070106138A1 (en) * | 2005-05-26 | 2007-05-10 | Beiski Ben Z | Intraoral apparatus for non-invasive blood and saliva monitoring & sensing |
| US20090143761A1 (en) * | 2005-06-03 | 2009-06-04 | Transdermal Patents Company, Llc | Agent delivery system and uses of same |
| WO2006133103A2 (en) * | 2005-06-03 | 2006-12-14 | Trans-Dermal Patents Company, Llc | Reservoir for delivery of agents |
| EP1905433A1 (en) * | 2005-07-15 | 2008-04-02 | Transcu Ltd. | Percutaneous absorption patch with application position indicating function, and iontophoresis device |
| JP4969812B2 (ja) * | 2005-07-22 | 2012-07-04 | 久光製薬株式会社 | ハイドロゲル組成物 |
| RU2008112156A (ru) | 2005-08-31 | 2009-10-10 | Алза Корпорейшн (Us) | Катод для осуществления электропереноса анионного медикамента |
| WO2007041322A2 (en) * | 2005-09-30 | 2007-04-12 | Tti Ellebeau, Inc. | Iontophoretic delivery of active agents conjugated to nanoparticles |
| EP1965856A2 (en) | 2005-12-30 | 2008-09-10 | Tti Ellebeau, Inc. | Iontophoretic systems, devices, and methods of delivery of active agents to biological interface |
| WO2007109274A2 (en) * | 2006-03-21 | 2007-09-27 | Alza Corporation | Hydratable polymeric ester matrix for drug electrotransport |
| US8246973B2 (en) * | 2006-06-21 | 2012-08-21 | Advanced Cardiovascular Systems, Inc. | Freeze-thaw method for modifying stent coating |
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| WO2008087803A1 (ja) * | 2007-01-16 | 2008-07-24 | Hokkaido University | 抗酸化成分を封入したイオントフォレーシス用リポソーム製剤 |
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| US20090105634A1 (en) * | 2007-10-17 | 2009-04-23 | Alza Corporation | Anodic Reservoir for Electrotransport of Cationic Drug |
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| JP2012501801A (ja) * | 2008-09-10 | 2012-01-26 | トランスキュー リミテッド | ヒドロキシプロピルセルロース（ｈｐｃ）をベースにした粘性液体を多孔質基材に薬剤投与する装置および方法、例えば連続ウェブをベースにしたプロセス |
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| US8301238B2 (en) | 2011-03-31 | 2012-10-30 | Incline Therapeutics, Inc. | Two-part electrotransport device |
| US8428708B1 (en) | 2012-05-21 | 2013-04-23 | Incline Therapeutics, Inc. | Self-test for analgesic product |
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| US9855211B2 (en) * | 2013-02-28 | 2018-01-02 | Novan, Inc. | Topical compositions and methods of using the same |
| US10478498B2 (en) | 2014-06-20 | 2019-11-19 | Reform Biologics, Llc | Excipient compounds for biopolymer formulations |
| GB2533827B (en) * | 2015-05-21 | 2016-12-21 | Gateway Devices Ltd | Intravenous access device |
| US20170136180A1 (en) * | 2015-09-25 | 2017-05-18 | Massachusetts Institute Of Technology | Stretchable, Robust and Biocompatible Hydrogel Electronics and Devices |
| WO2018013673A1 (en) | 2016-07-13 | 2018-01-18 | Reform Biologics, Llc | Stabilizing excipients for therapeutic protein formulations |
| CN106491517B (zh) * | 2016-11-23 | 2019-12-06 | 佛山科学技术学院 | 吡非尼酮pva水凝胶的制备方法及吡非尼酮pva水凝胶 |
| CN116473910B (zh) * | 2022-01-17 | 2026-06-26 | 奥信阳光(北京)药业科技有限公司 | 甲磺酸多拉司琼栓及其制备方法和用途 |
| CN116439678A (zh) * | 2023-03-30 | 2023-07-18 | 香港心脑血管健康工程研究中心有限公司 | 一种基于动脉血压图的高血压实时监测和闭环给药装置 |
| CN116570553B (zh) * | 2023-05-25 | 2026-07-31 | 上海交通大学医学院附属第九人民医院 | 一种载药导电凝胶、其制备方法及其在离子导入技术中的应用 |
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| CA1181915A (en) * | 1981-02-05 | 1985-02-05 | Nippon Oil Co., Ltd. | Process for preparing a hydrogel |
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| JPH0720544B2 (ja) * | 1988-12-27 | 1995-03-08 | 日本石油株式会社 | Ｐｖａヒドロゲルの製造法及びｍｒｉファントム |
| US5091185A (en) * | 1990-06-20 | 1992-02-25 | Monsanto Company | Coated veterinary implants |
| EP0516026A1 (en) * | 1991-05-28 | 1992-12-02 | Takeda Chemical Industries, Ltd. | Hydrogel and method of producing same |
| US5260066A (en) * | 1992-01-16 | 1993-11-09 | Srchem Incorporated | Cryogel bandage containing therapeutic agent |
| AU3938797A (en) * | 1996-08-29 | 1998-03-19 | Novo Nordisk A/S | Transdermal delivery of peptides |
| US6650934B2 (en) * | 1996-12-17 | 2003-11-18 | Alza Corp | Polymeric foam reservoirs for an electrotransport delivery device |
-
1997
- 1997-12-09 US US08/987,372 patent/US6039977A/en not_active Expired - Lifetime
-
1998
- 1998-11-17 TW TW087119029A patent/TWI231214B/zh not_active IP Right Cessation
- 1998-11-20 ZA ZA9810641A patent/ZA9810641B/xx unknown
- 1998-12-01 KR KR1020007006165A patent/KR100568482B1/ko not_active Expired - Fee Related
- 1998-12-01 AT AT98959589T patent/ATE266422T1/de not_active IP Right Cessation
- 1998-12-01 WO PCT/US1998/025120 patent/WO1999029348A1/en not_active Ceased
- 1998-12-01 JP JP2000524017A patent/JP2001525377A/ja active Pending
- 1998-12-01 AU AU15357/99A patent/AU1535799A/en not_active Abandoned
- 1998-12-01 DK DK98959589T patent/DK1037667T3/da active
- 1998-12-01 CA CA002313642A patent/CA2313642C/en not_active Expired - Fee Related
- 1998-12-01 ES ES98959589T patent/ES2221228T3/es not_active Expired - Lifetime
- 1998-12-01 PT PT98959589T patent/PT1037667E/pt unknown
- 1998-12-01 DE DE69823869T patent/DE69823869T2/de not_active Expired - Lifetime
- 1998-12-01 CN CNB988120623A patent/CN1147319C/zh not_active Expired - Fee Related
- 1998-12-01 EP EP98959589A patent/EP1037667B1/en not_active Expired - Lifetime
- 1998-12-07 AR ARP980106205A patent/AR017197A1/es active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DE69823869T2 (de) | 2005-05-19 |
| KR20010032839A (ko) | 2001-04-25 |
| EP1037667B1 (en) | 2004-05-12 |
| US6039977A (en) | 2000-03-21 |
| JP2001525377A (ja) | 2001-12-11 |
| CN1147319C (zh) | 2004-04-28 |
| WO1999029348A1 (en) | 1999-06-17 |
| EP1037667A1 (en) | 2000-09-27 |
| AR017197A1 (es) | 2001-08-22 |
| KR100568482B1 (ko) | 2006-04-07 |
| AU1535799A (en) | 1999-06-28 |
| CN1281372A (zh) | 2001-01-24 |
| ES2221228T3 (es) | 2004-12-16 |
| ATE266422T1 (de) | 2004-05-15 |
| PT1037667E (pt) | 2004-08-31 |
| TWI231214B (en) | 2005-04-21 |
| ZA9810641B (en) | 1999-05-24 |
| DK1037667T3 (da) | 2004-09-20 |
| DE69823869D1 (de) | 2004-06-17 |
| CA2313642A1 (en) | 1999-06-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20151201 |