ATE266422T1 - Pharmazeutische hydrogelformulierungen, vorrichtungen zur arzneistoffabgabe und verfahren - Google Patents

Pharmazeutische hydrogelformulierungen, vorrichtungen zur arzneistoffabgabe und verfahren

Info

Publication number
ATE266422T1
ATE266422T1 AT98959589T AT98959589T ATE266422T1 AT E266422 T1 ATE266422 T1 AT E266422T1 AT 98959589 T AT98959589 T AT 98959589T AT 98959589 T AT98959589 T AT 98959589T AT E266422 T1 ATE266422 T1 AT E266422T1
Authority
AT
Austria
Prior art keywords
methods
drug delivery
delivery devices
hydrogel formulations
pharmaceutical hydrogel
Prior art date
Application number
AT98959589T
Other languages
German (de)
English (en)
Inventor
Thomas O Murdock
Stephanus Pudjijanto
Subramanian S Venkatraman
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE266422T1 publication Critical patent/ATE266422T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0009—Galenical forms characterised by the drug release technique; Application systems commanded by energy involving or responsive to electricity, magnetism or acoustic waves; Galenical aspects of sonophoresis, iontophoresis, electroporation or electroosmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Medicinal Preparation (AREA)
AT98959589T 1997-12-09 1998-12-01 Pharmazeutische hydrogelformulierungen, vorrichtungen zur arzneistoffabgabe und verfahren ATE266422T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/987,372 US6039977A (en) 1997-12-09 1997-12-09 Pharmaceutical hydrogel formulations, and associated drug delivery devices and methods
PCT/US1998/025120 WO1999029348A1 (en) 1997-12-09 1998-12-01 Pharmaceutical hydrogel formulations, drug delivery devices and methods

Publications (1)

Publication Number Publication Date
ATE266422T1 true ATE266422T1 (de) 2004-05-15

Family

ID=25533223

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98959589T ATE266422T1 (de) 1997-12-09 1998-12-01 Pharmazeutische hydrogelformulierungen, vorrichtungen zur arzneistoffabgabe und verfahren

Country Status (16)

Country Link
US (1) US6039977A (enExample)
EP (1) EP1037667B1 (enExample)
JP (1) JP2001525377A (enExample)
KR (1) KR100568482B1 (enExample)
CN (1) CN1147319C (enExample)
AR (1) AR017197A1 (enExample)
AT (1) ATE266422T1 (enExample)
AU (1) AU1535799A (enExample)
CA (1) CA2313642C (enExample)
DE (1) DE69823869T2 (enExample)
DK (1) DK1037667T3 (enExample)
ES (1) ES2221228T3 (enExample)
PT (1) PT1037667E (enExample)
TW (1) TWI231214B (enExample)
WO (1) WO1999029348A1 (enExample)
ZA (1) ZA9810641B (enExample)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440457B1 (en) * 1993-05-27 2002-08-27 Alza Corporation Method of administering antidepressant dosage form
GB0005016D0 (en) * 2000-03-01 2000-04-26 Jumik Technologies Limited PVA-Containing compositions
JP4361710B2 (ja) 2000-04-19 2009-11-11 ジェネンテック・インコーポレーテッド 徐放製剤
KR100452972B1 (ko) * 2000-05-16 2004-10-14 주식회사 삼양사 경피투여용 하이드로젤 조성물
DE60231862D1 (de) * 2001-02-23 2009-05-20 Genentech Inc Erodierbare polymere zur injektion
CA2443326A1 (en) * 2001-04-04 2002-10-17 Alza Corporation Transdermal electrotransport delivery device including an antimicrobial compatible reservoir composition
PT1397155E (pt) * 2001-06-21 2015-12-07 Genentech Inc Formulação de libertação sustentada
DE10141650C1 (de) 2001-08-24 2002-11-28 Lohmann Therapie Syst Lts Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen
ITMI20012060A1 (it) * 2001-10-05 2003-04-05 Recordati Chem Pharm Nuovi eterocilcli n-acilati
AU2002351164A1 (en) * 2001-11-26 2003-06-10 Molecular Reflections, Inc. Microscale immobilization of molecules using a hydrogel and methods of use thereof
WO2004002571A1 (en) 2002-06-28 2004-01-08 Alza Corporation A reservoir for use in an electrotransport drug delivery device
US20040158194A1 (en) * 2003-02-06 2004-08-12 Wolff Andy And Beiski Ben Z. Oral devices and methods for controlled drug release
US20050142531A1 (en) * 2003-11-19 2005-06-30 David Rauser Peptidically buffered formulations for electrotransport applications and methods of making
CN1921829B (zh) * 2003-12-05 2010-05-05 纳米比亚医学调查研究有限公司 贴片
CN100386073C (zh) * 2004-03-03 2008-05-07 杭州民生药业集团有限公司 一种经皮给药系统
US7491263B2 (en) * 2004-04-05 2009-02-17 Technology Innovation, Llc Storage assembly
US20060135906A1 (en) * 2004-11-16 2006-06-22 Akihiko Matsumura Iontophoretic device and method for administering immune response-enhancing agents and compositions
US20070106138A1 (en) * 2005-05-26 2007-05-10 Beiski Ben Z Intraoral apparatus for non-invasive blood and saliva monitoring & sensing
US20090143761A1 (en) * 2005-06-03 2009-06-04 Transdermal Patents Company, Llc Agent delivery system and uses of same
WO2006133103A2 (en) * 2005-06-03 2006-12-14 Trans-Dermal Patents Company, Llc Reservoir for delivery of agents
EP1905433A1 (en) * 2005-07-15 2008-04-02 Transcu Ltd. Percutaneous absorption patch with application position indicating function, and iontophoresis device
JP4969812B2 (ja) * 2005-07-22 2012-07-04 久光製薬株式会社 ハイドロゲル組成物
RU2008112156A (ru) 2005-08-31 2009-10-10 Алза Корпорейшн (Us) Катод для осуществления электропереноса анионного медикамента
WO2007041322A2 (en) * 2005-09-30 2007-04-12 Tti Ellebeau, Inc. Iontophoretic delivery of active agents conjugated to nanoparticles
EP1965856A2 (en) 2005-12-30 2008-09-10 Tti Ellebeau, Inc. Iontophoretic systems, devices, and methods of delivery of active agents to biological interface
WO2007109274A2 (en) * 2006-03-21 2007-09-27 Alza Corporation Hydratable polymeric ester matrix for drug electrotransport
US8246973B2 (en) * 2006-06-21 2012-08-21 Advanced Cardiovascular Systems, Inc. Freeze-thaw method for modifying stent coating
JP2010502270A (ja) * 2006-08-29 2010-01-28 アルザ・コーポレーシヨン 水和可能な貯蔵器の水和測定付きの薬品電気輸送
US7538652B2 (en) * 2006-08-29 2009-05-26 International Business Machines Corporation Electrical component tuned by conductive layer deletion
US20080193514A1 (en) * 2006-11-02 2008-08-14 Transcu Ltd. Compostions and methods for iontophoresis delivery of active ingredients through hair follicles
EP2101864A2 (en) * 2006-12-20 2009-09-23 ALZA Corporation Anode for electrotransport of cationic drug
WO2008087803A1 (ja) * 2007-01-16 2008-07-24 Hokkaido University 抗酸化成分を封入したイオントフォレーシス用リポソーム製剤
US20080234627A1 (en) * 2007-03-22 2008-09-25 Wanda Dent Pivotally engaged multiple part electrotransport drug delivery device
NZ582049A (en) * 2007-05-18 2012-12-21 Tti Ellebeau Inc Transdermal delivery devices assuring an improved release of an active principle through a biological interface
JP2010187707A (ja) * 2007-06-12 2010-09-02 Hokkaido Univ インスリンを封入したイオントフォレーシス用リポソーム製剤
US20090043244A1 (en) * 2007-08-08 2009-02-12 Inan Omer T Electrotransport Drug Delivery Device Adaptable to Skin Resistance Change
US20090105634A1 (en) * 2007-10-17 2009-04-23 Alza Corporation Anodic Reservoir for Electrotransport of Cationic Drug
US20090105632A1 (en) * 2007-10-18 2009-04-23 Padmanabhan Rama V Electrotransport Of Lisuride
USD588274S1 (en) 2008-02-12 2009-03-10 Alza Corporation Skin-adhering drug delivery patch
US20090312689A1 (en) * 2008-06-05 2009-12-17 Alza Corporation Adjustable Current Electrotransport Fentanyl Delivery Device
JP2012501801A (ja) * 2008-09-10 2012-01-26 トランスキュー リミテッド ヒドロキシプロピルセルロース（ｈｐｃ）をベースにした粘性液体を多孔質基材に薬剤投与する装置および方法、例えば連続ウェブをベースにしたプロセス
US8048442B1 (en) 2008-09-16 2011-11-01 Abbott Cardiovascular Systems Inc. Modified heparin-based coatings and related drug eluting stents
US8301238B2 (en) 2011-03-31 2012-10-30 Incline Therapeutics, Inc. Two-part electrotransport device
US8428708B1 (en) 2012-05-21 2013-04-23 Incline Therapeutics, Inc. Self-test for analgesic product
US8428709B1 (en) 2012-06-11 2013-04-23 Incline Therapeutics, Inc. Current control for electrotransport drug delivery
USD699855S1 (en) 2012-11-12 2014-02-18 Incline Therapeutics, Inc. Iontophoretic drug delivery device
US9855211B2 (en) * 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
US10478498B2 (en) 2014-06-20 2019-11-19 Reform Biologics, Llc Excipient compounds for biopolymer formulations
GB2533827B (en) * 2015-05-21 2016-12-21 Gateway Devices Ltd Intravenous access device
US20170136180A1 (en) * 2015-09-25 2017-05-18 Massachusetts Institute Of Technology Stretchable, Robust and Biocompatible Hydrogel Electronics and Devices
WO2018013673A1 (en) 2016-07-13 2018-01-18 Reform Biologics, Llc Stabilizing excipients for therapeutic protein formulations
CN106491517B (zh) * 2016-11-23 2019-12-06 佛山科学技术学院 吡非尼酮pva水凝胶的制备方法及吡非尼酮pva水凝胶
CN116473910B (zh) * 2022-01-17 2026-06-26 奥信阳光(北京)药业科技有限公司 甲磺酸多拉司琼栓及其制备方法和用途
CN116439678A (zh) * 2023-03-30 2023-07-18 香港心脑血管健康工程研究中心有限公司 一种基于动脉血压图的高血压实时监测和闭环给药装置
CN116570553B (zh) * 2023-05-25 2026-07-31 上海交通大学医学院附属第九人民医院 一种载药导电凝胶、其制备方法及其在离子导入技术中的应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1181915A (en) * 1981-02-05 1985-02-05 Nippon Oil Co., Ltd. Process for preparing a hydrogel
DE3278911D1 (en) * 1981-05-16 1988-09-22 Nippon Oil Co Ltd Process for the preparation of gel for use as cooling medium
US4542013A (en) * 1981-07-08 1985-09-17 Key Pharmaceuticals, Inc. Trinitroglycerol sustained release vehicles and preparation therefrom
US4593053A (en) * 1984-12-07 1986-06-03 Medtronic, Inc. Hydrophilic pressure sensitive biomedical adhesive composition
JPS61218517A (ja) * 1985-03-25 1986-09-29 Bio Materiaru Yunibaasu:Kk 経皮吸収製剤
EP0303445A1 (en) * 1987-08-13 1989-02-15 Walton S.A. Clebopride transdermal patch
JPH0720544B2 (ja) * 1988-12-27 1995-03-08 日本石油株式会社 Ｐｖａヒドロゲルの製造法及びｍｒｉファントム
US5091185A (en) * 1990-06-20 1992-02-25 Monsanto Company Coated veterinary implants
EP0516026A1 (en) * 1991-05-28 1992-12-02 Takeda Chemical Industries, Ltd. Hydrogel and method of producing same
US5260066A (en) * 1992-01-16 1993-11-09 Srchem Incorporated Cryogel bandage containing therapeutic agent
AU3938797A (en) * 1996-08-29 1998-03-19 Novo Nordisk A/S Transdermal delivery of peptides
US6650934B2 (en) * 1996-12-17 2003-11-18 Alza Corp Polymeric foam reservoirs for an electrotransport delivery device

Also Published As

Publication number Publication date
DE69823869T2 (de) 2005-05-19
KR20010032839A (ko) 2001-04-25
EP1037667B1 (en) 2004-05-12
US6039977A (en) 2000-03-21
CA2313642C (en) 2008-09-30
JP2001525377A (ja) 2001-12-11
CN1147319C (zh) 2004-04-28
WO1999029348A1 (en) 1999-06-17
EP1037667A1 (en) 2000-09-27
AR017197A1 (es) 2001-08-22
KR100568482B1 (ko) 2006-04-07
AU1535799A (en) 1999-06-28
CN1281372A (zh) 2001-01-24
ES2221228T3 (es) 2004-12-16
PT1037667E (pt) 2004-08-31
TWI231214B (en) 2005-04-21
ZA9810641B (en) 1999-05-24
DK1037667T3 (da) 2004-09-20
DE69823869D1 (de) 2004-06-17
CA2313642A1 (en) 1999-06-17

Similar Documents

Publication Publication Date Title
DE69823869D1 (de) Pharmazeutische hydrogelformulierungen, vorrichtungen zur arzneistoffabgabe und verfahren
ATE516812T1 (de) Pharmazeutische formulierungen zur anhaltenden arzneimittelfreisetzung
DE69812089D1 (de) Pharmazeutische omeprazol-formulierung
ATE289500T1 (de) Ophtalmologische medikamentenzuführvorrichtung
DE69909801D1 (de) Oral verabreichtes system zur zeitlich und räumlich gesteuerten arzneistoffabgabe
DE69935681D1 (de) Vorrichtungen zur Medikamentverabreichung
EE05506B1 (et) Ravimi manustamise vahend eriti progestiinide ja”strogeenide manustamiseks
EE200100714A (et) Farmatseutiliste ravimvormide pihustamissüsteemidja -meetodid
DE60013445D1 (de) Pharmazeutische dosierungsformen zur kontrollierter pulsierender abgabe
DK1473003T3 (da) Lægemiddeladministrationsanordning
DE60019949D1 (de) Arzneimittel enthaltendes system zur oralen abgabevorrichtung
ATE548029T1 (de) Wirkstoffabgabevorrichtung mit verzögerter freisetzung
SG65061A1 (en) Drug delivery system for two or more active substances
HUP0104168A3 (en) Spray on bandage and drug delivery system
DE69832298D1 (de) Gerät zur kontrollierten abgabe von pharmazeutischen und medizinischen produkten
ATE221374T1 (de) Lyophilisierte stabile pharmazeutische formulierung
DE69934773D1 (de) Vorrichtung zur Verabreichung von Medikamenten
DE69828895D1 (de) Alpha-aryl-n-alkylnitrone sowie diese enthaltende pharmazeutische zubereitungen
HUP0104687A3 (en) Methods for preparing coated drug particles and pharmaceutical formulations thereof
EP1036573A4 (en) DEVICE FOR ADMINISTERING A SUBSTANCE THROUGH THE SKIN OR A MUCUTINE
EP1183027A4 (en) PHARMACEUTICAL COMPOSITIONS AND METHODS WHICH CONTAIN MORPHINE FOR INTRANASAL ADMINISTRATION
DE69830095D1 (de) Pharmazeutischer, kosmetischer oder dermo-pharmazeutischer Patch zur Verabreichung mehrerer verschiedenartiger Aktivstoffe
ATE383868T1 (de) Pharmazeutische formulierung enthaltend megalatran und dessen pro-pharmaka
DE69807768D1 (de) Rapamycin enthaltende Formulierungen zur oralen Verabreichung
ZA981775B (en) Pharmaceutical formulations containing poorly soluble drug substances

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1037667

Country of ref document: EP

REN Ceased due to non-payment of the annual fee