DE60231862D1 - Erodierbare polymere zur injektion - Google Patents
Erodierbare polymere zur injektionInfo
- Publication number
- DE60231862D1 DE60231862D1 DE60231862T DE60231862T DE60231862D1 DE 60231862 D1 DE60231862 D1 DE 60231862D1 DE 60231862 T DE60231862 T DE 60231862T DE 60231862 T DE60231862 T DE 60231862T DE 60231862 D1 DE60231862 D1 DE 60231862D1
- Authority
- DE
- Germany
- Prior art keywords
- injection
- beneficial agent
- composition
- erodable polymers
- solvent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Inorganic Chemistry (AREA)
- Dermatology (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Materials For Medical Uses (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US27084501P | 2001-02-23 | 2001-02-23 | |
PCT/US2002/005445 WO2002067991A1 (en) | 2001-02-23 | 2002-02-22 | Erodible polymers for injection |
US10/080,502 US7824700B2 (en) | 2001-02-23 | 2002-02-22 | Erodible polymers for injection |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60231862D1 true DE60231862D1 (de) | 2009-05-20 |
Family
ID=26763604
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60231862T Expired - Lifetime DE60231862D1 (de) | 2001-02-23 | 2002-02-22 | Erodierbare polymere zur injektion |
Country Status (10)
Country | Link |
---|---|
US (2) | US7824700B2 (de) |
EP (1) | EP1372729B1 (de) |
JP (2) | JP4724354B2 (de) |
AT (1) | ATE427760T1 (de) |
AU (1) | AU2002242231B2 (de) |
CA (1) | CA2439120C (de) |
DE (1) | DE60231862D1 (de) |
DK (1) | DK1372729T3 (de) |
IL (2) | IL157531A0 (de) |
WO (1) | WO2002067991A1 (de) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE60231862D1 (de) * | 2001-02-23 | 2009-05-20 | Genentech Inc | Erodierbare polymere zur injektion |
AU2002359407B2 (en) * | 2001-11-14 | 2008-02-28 | Durect Corporation | Catheter injectable depot compositions and uses thereof |
NZ533435A (en) * | 2001-11-14 | 2007-10-26 | Alza Corp | Injectable depot compositions and uses thereof |
US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
AR039729A1 (es) * | 2002-06-25 | 2005-03-09 | Alza Corp | Formulaciones de deposito de corta duracion |
AU2003256849A1 (en) | 2002-07-31 | 2004-02-16 | Alza Corporation | Injectable multimodal polymer depot compositions and uses thereof |
MXPA05001242A (es) | 2002-07-31 | 2005-06-08 | Alza Corp | Composiciones de deposito inyectable y usos de las mismas. |
ATE418323T1 (de) | 2002-11-06 | 2009-01-15 | Alza Corp | Depot-formulierungen mit verzögerter freisetzung |
HUE025239T2 (en) | 2003-09-03 | 2016-03-29 | Miscon Trading S A | Methods for treating endometriosis |
US20050106214A1 (en) * | 2003-11-14 | 2005-05-19 | Guohua Chen | Excipients in drug delivery vehicles |
US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
KR101434935B1 (ko) | 2005-11-30 | 2014-10-01 | 애브비 인코포레이티드 | 아밀로이드 베타 단백질에 대한 모노클로날 항체 및 이의용도 |
ES2562878T3 (es) | 2007-05-25 | 2016-03-08 | Indivior Uk Limited | Formulaciones de liberación sostenida de compuestos de risperidona |
DK2170283T3 (en) | 2007-06-22 | 2019-04-15 | Univ Texas | CREATION OF STABLE SUBMICRON Peptide OR PROTEIN PARTICLES BY THIN FILM FREEZING |
US8779094B2 (en) * | 2008-11-16 | 2014-07-15 | Board Of Regents, The University Of Texas System | Low viscosity highly concentrated suspensions |
CN103384528B (zh) * | 2010-11-24 | 2016-04-13 | 杜雷科特公司 | 生物可降解的药物递送组合物 |
EP2782590A4 (de) * | 2011-11-23 | 2016-08-03 | Durect Corp | Biologisch abbaubare und mittels strahlung sterilisierte arzneimittelabgabezusammensetzungen |
WO2014120834A1 (en) | 2013-01-29 | 2014-08-07 | Sutterlin Chester Evan | Occipital plate assemblies with polyaxial head connectors |
EP2986278A1 (de) | 2013-03-11 | 2016-02-24 | DURECT Corporation | Injizierbare zusammensetzung mit gesteuerter freisetzung mit einem hochviskosen flüssigen träger |
US20140308352A1 (en) | 2013-03-11 | 2014-10-16 | Zogenix Inc. | Compositions and methods involving polymer, solvent, and high viscosity liquid carrier material |
EP3079668A1 (de) | 2013-12-09 | 2016-10-19 | Durect Corporation | Pharmazeutisch aktive wirkstoffkomplexe, polymerkomplexe und zusammensetzungen und verfahren damit |
US11000520B2 (en) | 2014-11-07 | 2021-05-11 | Indivior Uk Limited | Buprenorphine dosing regimens |
US10682340B2 (en) | 2016-06-30 | 2020-06-16 | Durect Corporation | Depot formulations |
JP7051721B2 (ja) | 2016-06-30 | 2022-04-11 | デュレクト コーポレーション | デポー製剤 |
US10646484B2 (en) | 2017-06-16 | 2020-05-12 | Indivior Uk Limited | Methods to treat opioid use disorder |
CA3167217A1 (en) | 2020-01-13 | 2021-07-22 | Durect Corporation | Sustained release drug delivery systems with reduced impurities and related methods |
Family Cites Families (55)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2916711A1 (de) * | 1979-04-25 | 1980-11-06 | Behringwerke Ag | Blutgerinnungsfaktoren und verfahren zu ihrer herstellung |
IL79681A (en) | 1985-08-12 | 1991-06-10 | Int Minerals & Chem Corp | Transition metal complexes of growth hormones and their prolonged release compositions |
WO1989003671A1 (en) | 1987-10-29 | 1989-05-05 | Dainippon Pharmaceutical Co., Ltd. | Sustained-release preparation |
US5096885A (en) * | 1988-04-15 | 1992-03-17 | Genentech, Inc. | Human growth hormone formulation |
US4938763B1 (en) * | 1988-10-03 | 1995-07-04 | Atrix Lab Inc | Biodegradable in-situ forming implants and method of producing the same |
US4975271A (en) * | 1988-12-19 | 1990-12-04 | Vipont Pharmaceutical, Inc. | Muscosal delivery systems for treatment of periodontal disease |
US5324520A (en) * | 1988-12-19 | 1994-06-28 | Vipont Pharmaceutical, Inc. | Intragingival delivery systems for treatment of periodontal disease |
US5019400A (en) * | 1989-05-01 | 1991-05-28 | Enzytech, Inc. | Very low temperature casting of controlled release microspheres |
US5324519A (en) * | 1989-07-24 | 1994-06-28 | Atrix Laboratories, Inc. | Biodegradable polymer composition |
US5077049A (en) | 1989-07-24 | 1991-12-31 | Vipont Pharmaceutical, Inc. | Biodegradable system for regenerating the periodontium |
US5487897A (en) * | 1989-07-24 | 1996-01-30 | Atrix Laboratories, Inc. | Biodegradable implant precursor |
MX173182B (es) | 1989-10-02 | 1994-02-07 | Southern Res Inst | Composicion para formar un injerto biodegradable o injertos biodegradables formadores in situ obtenidos a partir de la misma |
US5133981A (en) * | 1989-11-17 | 1992-07-28 | Atrix Laboratories, Inc. | Purification of benzophenanthridine alkaloids extracts from alkaloid extracts |
CA2046830C (en) | 1990-07-19 | 1999-12-14 | Patrick P. Deluca | Drug delivery system involving inter-action between protein or polypeptide and hydrophobic biodegradable polymer |
ZA918526B (en) * | 1990-10-30 | 1992-08-26 | Alza Corp | Drug delivery system and method |
US5416071A (en) * | 1991-03-12 | 1995-05-16 | Takeda Chemical Industries, Ltd. | Water-soluble composition for sustained-release containing epo and hyaluronic acid |
WO1992017200A2 (en) | 1991-03-28 | 1992-10-15 | Genentech, Inc. | Stable growth hormone metal ion formulations |
US5252338A (en) * | 1991-06-27 | 1993-10-12 | Alza Corporation | Therapy delayed |
AU2605592A (en) * | 1991-10-15 | 1993-04-22 | Atrix Laboratories, Inc. | Polymeric compositions useful as controlled release implants |
US5912015A (en) * | 1992-03-12 | 1999-06-15 | Alkermes Controlled Therapeutics, Inc. | Modulated release from biocompatible polymers |
US5711968A (en) * | 1994-07-25 | 1998-01-27 | Alkermes Controlled Therapeutics, Inc. | Composition and method for the controlled release of metal cation-stabilized interferon |
US5242910A (en) * | 1992-10-13 | 1993-09-07 | The Procter & Gamble Company | Sustained release compositions for treating periodontal disease |
ES2151541T3 (es) * | 1992-12-02 | 2001-01-01 | Alkermes Inc | Microesferas que contienen hormona del crecimiento de liberacion prolongada. |
MY113268A (en) * | 1992-12-29 | 2002-01-31 | Insite Vision Incorporated | Plasticized bioerodible controlled delivery system |
RU2143889C1 (ru) * | 1993-02-23 | 2000-01-10 | Генентек, Инк. | Способ стабилизации полипептида, способы получения композиций полипептида и композиции |
US6087324A (en) * | 1993-06-24 | 2000-07-11 | Takeda Chemical Industries, Ltd. | Sustained-release preparation |
US6080429A (en) * | 1993-10-25 | 2000-06-27 | Genentech, Inc. | Method for drying microspheres |
CA2143044C (en) * | 1994-02-21 | 2005-04-12 | Yasutaka Igari | Matrix for sustained-release preparation |
US5556905A (en) * | 1994-03-30 | 1996-09-17 | Reilly Industries, Inc. | Physically-modified degradable thermoplastic compositions |
PT754032E (pt) * | 1994-04-08 | 2002-05-31 | Atrix Lab Inc | Composicoes liquidas para difusao |
US6007845A (en) * | 1994-07-22 | 1999-12-28 | Massachusetts Institute Of Technology | Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers |
US5626862A (en) * | 1994-08-02 | 1997-05-06 | Massachusetts Institute Of Technology | Controlled local delivery of chemotherapeutic agents for treating solid tumors |
US5904935A (en) * | 1995-06-07 | 1999-05-18 | Alza Corporation | Peptide/protein suspending formulations |
US5747058A (en) * | 1995-06-07 | 1998-05-05 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system |
US5736152A (en) * | 1995-10-27 | 1998-04-07 | Atrix Laboratories, Inc. | Non-polymeric sustained release delivery system |
CA2192773C (en) * | 1995-12-15 | 2008-09-23 | Hiroaki Okada | Production of sustained-release preparation for injection |
US5980945A (en) * | 1996-01-16 | 1999-11-09 | Societe De Conseils De Recherches Et D'applications Scientifique S.A. | Sustained release drug formulations |
US5792477A (en) * | 1996-05-07 | 1998-08-11 | Alkermes Controlled Therapeutics, Inc. Ii | Preparation of extended shelf-life biodegradable, biocompatible microparticles containing a biologically active agent |
US5932547A (en) * | 1996-07-03 | 1999-08-03 | Alza Corporation | Non-aqueous polar aprotic peptide formulations |
US5981489A (en) * | 1996-07-18 | 1999-11-09 | Alza Corporation | Non-aqueous protic peptide formulations |
DK0839525T3 (da) * | 1996-10-31 | 2004-11-29 | Takeda Pharmaceutical | Præparat med forlænget frigivelse |
ATE233088T1 (de) * | 1996-12-20 | 2003-03-15 | Takeda Chemical Industries Ltd | Verfahren zur herstellung einer zusammensetzung mit verzoegerter abgabe |
DE69735384T2 (de) * | 1996-12-20 | 2006-08-10 | Alza Corp., Mountain View | Gelzusammensetzungen und verfahren |
US6113947A (en) * | 1997-06-13 | 2000-09-05 | Genentech, Inc. | Controlled release microencapsulated NGF formulation |
US6191107B1 (en) * | 1997-09-26 | 2001-02-20 | Takeda Chemical Industries, Ltd. | Complex of human growth hormone and zinc |
FR2768967B1 (fr) * | 1997-09-29 | 1999-12-17 | Liliane Hermet | Procede de fabrication et de reproduction d'au moins une partie d'un objet ou d'un individu |
US6039977A (en) * | 1997-12-09 | 2000-03-21 | Alza Corporation | Pharmaceutical hydrogel formulations, and associated drug delivery devices and methods |
IL137982A0 (en) * | 1998-03-19 | 2001-10-31 | Merck & Co Inc | Liquid polymeric compositions of controlled release of bioactive substances |
US6174547B1 (en) * | 1999-07-14 | 2001-01-16 | Alza Corporation | Dosage form comprising liquid formulation |
US6143314A (en) * | 1998-10-28 | 2000-11-07 | Atrix Laboratories, Inc. | Controlled release liquid delivery compositions with low initial drug burst |
WO2000078335A1 (en) | 1999-06-18 | 2000-12-28 | Southern Biosystems, Inc. | COMPOSITIONS FOR CONTROLLED RELEASE OF THE HORMONE GnRH AND ITS ANALOGS |
CN1283215C (zh) * | 2000-06-28 | 2006-11-08 | A·J·舒克拉 | 生物活性物质的可生物降解载体和释放系统 |
DE60231862D1 (de) | 2001-02-23 | 2009-05-20 | Genentech Inc | Erodierbare polymere zur injektion |
NZ533435A (en) | 2001-11-14 | 2007-10-26 | Alza Corp | Injectable depot compositions and uses thereof |
AU2002359407B2 (en) | 2001-11-14 | 2008-02-28 | Durect Corporation | Catheter injectable depot compositions and uses thereof |
-
2002
- 2002-02-22 DE DE60231862T patent/DE60231862D1/de not_active Expired - Lifetime
- 2002-02-22 DK DK02707855T patent/DK1372729T3/da active
- 2002-02-22 AU AU2002242231A patent/AU2002242231B2/en not_active Expired
- 2002-02-22 WO PCT/US2002/005445 patent/WO2002067991A1/en active Application Filing
- 2002-02-22 US US10/080,502 patent/US7824700B2/en not_active Expired - Lifetime
- 2002-02-22 EP EP02707855A patent/EP1372729B1/de not_active Expired - Lifetime
- 2002-02-22 JP JP2002567356A patent/JP4724354B2/ja not_active Expired - Lifetime
- 2002-02-22 AT AT02707855T patent/ATE427760T1/de not_active IP Right Cessation
- 2002-02-22 IL IL15753102A patent/IL157531A0/xx unknown
- 2002-02-22 CA CA2439120A patent/CA2439120C/en not_active Expired - Lifetime
-
2003
- 2003-08-21 IL IL157531A patent/IL157531A/en unknown
-
2010
- 2010-06-24 US US12/823,027 patent/US8501216B2/en not_active Expired - Lifetime
- 2010-07-02 JP JP2010151869A patent/JP2010265286A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE427760T1 (de) | 2009-04-15 |
IL157531A (en) | 2008-07-08 |
JP2010265286A (ja) | 2010-11-25 |
JP4724354B2 (ja) | 2011-07-13 |
US20020173552A1 (en) | 2002-11-21 |
US20110152190A1 (en) | 2011-06-23 |
JP2004536036A (ja) | 2004-12-02 |
IL157531A0 (en) | 2004-03-28 |
EP1372729B1 (de) | 2009-04-08 |
CA2439120C (en) | 2011-07-05 |
CA2439120A1 (en) | 2002-09-06 |
WO2002067991A1 (en) | 2002-09-06 |
EP1372729A1 (de) | 2004-01-02 |
US7824700B2 (en) | 2010-11-02 |
DK1372729T3 (da) | 2009-06-22 |
AU2002242231B2 (en) | 2007-09-06 |
US8501216B2 (en) | 2013-08-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |