KR100526212B1 - 치환된 2-(2,6-다이옥소피페리딘-3-일)-프탈이미드와치환된2-(2,6-다이옥소피페리딘-3-일)-1-옥소아이소인돌린과ＴＮＦα농도를 감소시키는 방법 - Google Patents

치환된 2-(2,6-다이옥소피페리딘-3-일)-프탈이미드와치환된2-(2,6-다이옥소피페리딘-3-일)-1-옥소아이소인돌린과ＴＮＦα농도를 감소시키는 방법 Download PDF

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KR100526212B1
KR100526212B1 KR10-1999-7011076A KR19997011076A KR100526212B1 KR 100526212 B1 KR100526212 B1 KR 100526212B1 KR 19997011076 A KR19997011076 A KR 19997011076A KR 100526212 B1 KR100526212 B1 KR 100526212B1
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tnfα
acid
compounds
substituted
amino
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KR20010013097A (ko
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뮬러조지더블유
스터어링데이비드아이
첸로저센츄
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셀진 코포레이션
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
KR10-1999-7011076A 1997-05-30 1998-05-28 치환된 2-(2,6-다이옥소피페리딘-3-일)-프탈이미드와치환된2-(2,6-다이옥소피페리딘-3-일)-1-옥소아이소인돌린과ＴＮＦα농도를 감소시키는 방법 Expired - Fee Related KR100526212B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US4827897P 1997-05-30 1997-05-30
US60/048,278 1997-05-30
PCT/US1998/010886 WO1998054170A1 (en) 1997-05-30 1998-05-28 SUBSTITUTED 2-(2,6-DIOXOPIPERIDIN-3-YL)-PHTHALIMIDES AND 1-OXOISOINDOLINES AND METHOD OF REDUCING TNFα LEVELS

Publications (2)

Publication Number Publication Date
KR20010013097A KR20010013097A (ko) 2001-02-26
KR100526212B1 true KR100526212B1 (ko) 2005-11-03

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KR10-1999-7011076A Expired - Fee Related KR100526212B1 (ko) 1997-05-30 1998-05-28 치환된 2-(2,6-다이옥소피페리딘-3-일)-프탈이미드와치환된2-(2,6-다이옥소피페리딘-3-일)-1-옥소아이소인돌린과ＴＮＦα농도를 감소시키는 방법

Country Status (24)

Country Link
US (3) US6395754B1 (enExample)
EP (3) EP0984955B1 (enExample)
JP (2) JP4307567B2 (enExample)
KR (1) KR100526212B1 (enExample)
CN (3) CN1911927A (enExample)
AT (2) ATE401319T1 (enExample)
AU (1) AU741982B2 (enExample)
CA (2) CA2291218C (enExample)
CY (1) CY1108348T1 (enExample)
CZ (1) CZ299812B6 (enExample)
DE (2) DE69825994T2 (enExample)
DK (2) DK1486496T3 (enExample)
ES (3) ES2229497T3 (enExample)
FI (1) FI19992490L (enExample)
HU (2) HU228769B1 (enExample)
MC (1) MC225A7 (enExample)
NO (6) NO322080B1 (enExample)
NZ (1) NZ501429A (enExample)
PL (1) PL193276B1 (enExample)
PT (2) PT1486496E (enExample)
RU (1) RU2209207C2 (enExample)
SK (1) SK163099A3 (enExample)
TR (4) TR200000107T2 (enExample)
WO (1) WO1998054170A1 (enExample)

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