PL1907373T3 - Sposób wytwarzania związków 4-amino-2-(2,6-diokso-piperydyn-3-ylo)izoindolino-1,3-dionu - Google Patents

Sposób wytwarzania związków 4-amino-2-(2,6-diokso-piperydyn-3-ylo)izoindolino-1,3-dionu

Info

Publication number
PL1907373T3
PL1907373T3 PL06786385T PL06786385T PL1907373T3 PL 1907373 T3 PL1907373 T3 PL 1907373T3 PL 06786385 T PL06786385 T PL 06786385T PL 06786385 T PL06786385 T PL 06786385T PL 1907373 T3 PL1907373 T3 PL 1907373T3
Authority
PL
Poland
Prior art keywords
dioxopiperidin
isoindoline
amino
processes
preparation
Prior art date
Application number
PL06786385T
Other languages
English (en)
Inventor
George W Muller
Manohar T Saindane
Chuansheng Ge
Roger Chen
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37305020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL1907373(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of PL1907373T3 publication Critical patent/PL1907373T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
PL06786385T 2005-06-30 2006-06-29 Sposób wytwarzania związków 4-amino-2-(2,6-diokso-piperydyn-3-ylo)izoindolino-1,3-dionu PL1907373T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69622405P 2005-06-30 2005-06-30
PCT/US2006/026210 WO2007005972A1 (en) 2005-06-30 2006-06-29 Processes for the preparation of 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds
EP06786385A EP1907373B1 (en) 2005-06-30 2006-06-29 Processes for the preparation of 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds

Publications (1)

Publication Number Publication Date
PL1907373T3 true PL1907373T3 (pl) 2013-05-31

Family

ID=37305020

Family Applications (2)

Application Number Title Priority Date Filing Date
PL11175056T PL2380887T3 (pl) 2005-06-30 2006-06-29 Sposób wytwarzania związków 4-amino-2-(2,6-diokso-piperydyn-3-ylo)izoindolino-1,3-dionu
PL06786385T PL1907373T3 (pl) 2005-06-30 2006-06-29 Sposób wytwarzania związków 4-amino-2-(2,6-diokso-piperydyn-3-ylo)izoindolino-1,3-dionu

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL11175056T PL2380887T3 (pl) 2005-06-30 2006-06-29 Sposób wytwarzania związków 4-amino-2-(2,6-diokso-piperydyn-3-ylo)izoindolino-1,3-dionu

Country Status (25)

Country Link
US (5) US7994327B2 (pl)
EP (2) EP1907373B1 (pl)
JP (2) JP5366544B2 (pl)
KR (2) KR101342241B1 (pl)
CN (2) CN102643267B (pl)
AU (1) AU2006265019B2 (pl)
BR (1) BRPI0612803A2 (pl)
CA (2) CA2612612C (pl)
CR (1) CR9697A (pl)
DK (2) DK1907373T3 (pl)
EC (1) ECSP088154A (pl)
ES (2) ES2402204T3 (pl)
HK (2) HK1121447A1 (pl)
HR (2) HRP20130102T1 (pl)
IL (2) IL188330A (pl)
ME (1) ME01513B (pl)
MX (1) MX2007016290A (pl)
NZ (1) NZ565309A (pl)
PE (2) PE20100151A1 (pl)
PL (2) PL2380887T3 (pl)
PT (2) PT1907373E (pl)
RS (2) RS53030B (pl)
SI (2) SI1907373T1 (pl)
WO (1) WO2007005972A1 (pl)
ZA (1) ZA200800828B (pl)

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CN101817813B (zh) * 2010-01-15 2013-04-10 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚酮-2-基)-2,6-哌啶二酮晶体ⅳ及其药用组合物
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CN103288797B (zh) * 2013-05-17 2016-03-02 宁波百思佳医药科技有限公司 一种用亚砜类溶剂纯化Pomalidomide的方法
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CN104557858B (zh) * 2013-10-29 2018-06-01 上海医药工业研究院 一种泊利度胺的制备方法
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CN103724323B (zh) * 2014-01-20 2016-08-17 上海医药工业研究院 泊马度胺的制备方法
CN104016967A (zh) * 2014-04-04 2014-09-03 南京工业大学 一种泊利度胺的合成方法
CN105440013B (zh) * 2014-08-29 2018-10-09 杭州和泽医药科技有限公司 一种泊马度胺的制备方法
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CN106432045B (zh) * 2016-06-29 2018-12-18 深圳海王医药科技研究院有限公司 一种泊马度胺杂质的合成方法
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CN101531653B (zh) 2008-03-13 2014-07-09 峡江和美药业有限公司 3-(4-氨基-1-氧代-1,3-二氢异吲哚-2-基)哌啶-2,6-二酮及其衍生物的盐或盐的多晶型物及其制备和应用

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