SI2380887T1 - Postopki priprave spojin 4-amino-2-/2,6-dioksopiperidin-3-il)izoindolin -1,3-diona - Google Patents

Postopki priprave spojin 4-amino-2-/2,6-dioksopiperidin-3-il)izoindolin -1,3-diona

Info

Publication number
SI2380887T1
SI2380887T1 SI200631669T SI200631669T SI2380887T1 SI 2380887 T1 SI2380887 T1 SI 2380887T1 SI 200631669 T SI200631669 T SI 200631669T SI 200631669 T SI200631669 T SI 200631669T SI 2380887 T1 SI2380887 T1 SI 2380887T1
Authority
SI
Slovenia
Prior art keywords
dioxopiperidin
isoindoline
amino
processes
preparation
Prior art date
Application number
SI200631669T
Other languages
English (en)
Inventor
George W. Muller
Manohar T. Saindane
Chuansheng Ge
Roger Chen
Original Assignee
Celgene Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37305020&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SI2380887(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Celgene Corporation filed Critical Celgene Corporation
Publication of SI2380887T1 publication Critical patent/SI2380887T1/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
SI200631669T 2005-06-30 2006-06-29 Postopki priprave spojin 4-amino-2-/2,6-dioksopiperidin-3-il)izoindolin -1,3-diona SI2380887T1 (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69622405P 2005-06-30 2005-06-30
EP11175056.8A EP2380887B1 (en) 2005-06-30 2006-06-29 Processes for the preparation of 4-amino-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione compounds

Publications (1)

Publication Number Publication Date
SI2380887T1 true SI2380887T1 (sl) 2013-12-31

Family

ID=37305020

Family Applications (2)

Application Number Title Priority Date Filing Date
SI200631669T SI2380887T1 (sl) 2005-06-30 2006-06-29 Postopki priprave spojin 4-amino-2-/2,6-dioksopiperidin-3-il)izoindolin -1,3-diona
SI200631524T SI1907373T1 (sl) 2005-06-30 2006-06-29 Postopki za pripravo 4-amino-2-(2.6-dioksopiperidin-3-il)izoindolin-1,3-dionskih spojin

Family Applications After (1)

Application Number Title Priority Date Filing Date
SI200631524T SI1907373T1 (sl) 2005-06-30 2006-06-29 Postopki za pripravo 4-amino-2-(2.6-dioksopiperidin-3-il)izoindolin-1,3-dionskih spojin

Country Status (25)

Country Link
US (5) US7994327B2 (sl)
EP (2) EP1907373B1 (sl)
JP (2) JP5366544B2 (sl)
KR (2) KR101342241B1 (sl)
CN (2) CN102643267B (sl)
AU (1) AU2006265019B2 (sl)
BR (1) BRPI0612803A2 (sl)
CA (2) CA2612612C (sl)
CR (1) CR9697A (sl)
DK (2) DK2380887T3 (sl)
EC (1) ECSP088154A (sl)
ES (2) ES2402204T3 (sl)
HK (2) HK1121447A1 (sl)
HR (2) HRP20130102T1 (sl)
IL (2) IL188330A (sl)
ME (1) ME01513B (sl)
MX (1) MX2007016290A (sl)
NZ (1) NZ565309A (sl)
PE (2) PE20100151A1 (sl)
PL (2) PL1907373T3 (sl)
PT (2) PT1907373E (sl)
RS (2) RS52704B (sl)
SI (2) SI2380887T1 (sl)
WO (1) WO2007005972A1 (sl)
ZA (1) ZA200800828B (sl)

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CN101580501B (zh) * 2009-06-01 2011-03-09 南京卡文迪许生物工程技术有限公司 3-(取代二氢异吲哚酮-2-基)-2,6-哌啶二酮的合成方法及其中间体
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CN103275062B (zh) * 2013-05-17 2016-04-13 宁波百思佳医药科技有限公司 一种Pomalidomide的纯化方法
CN103288797B (zh) * 2013-05-17 2016-03-02 宁波百思佳医药科技有限公司 一种用亚砜类溶剂纯化Pomalidomide的方法
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CN104557858B (zh) * 2013-10-29 2018-06-01 上海医药工业研究院 一种泊利度胺的制备方法
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CN103724323B (zh) * 2014-01-20 2016-08-17 上海医药工业研究院 泊马度胺的制备方法
CN104016967A (zh) * 2014-04-04 2014-09-03 南京工业大学 一种泊利度胺的合成方法
CN105440013B (zh) * 2014-08-29 2018-10-09 杭州和泽医药科技有限公司 一种泊马度胺的制备方法
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CN106432045B (zh) * 2016-06-29 2018-12-18 深圳海王医药科技研究院有限公司 一种泊马度胺杂质的合成方法
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Publication number Publication date
KR20130029442A (ko) 2013-03-22
ES2402204T3 (es) 2013-04-29
IL188330A (en) 2013-09-30
ME01513B (me) 2014-04-20
HK1168851A1 (zh) 2013-01-11
PE20070103A1 (es) 2007-02-06
EP2380887B1 (en) 2013-08-07
CN102643267A (zh) 2012-08-22
SI1907373T1 (sl) 2013-03-29
DK2380887T3 (da) 2013-10-07
JP5366544B2 (ja) 2013-12-11
CA2823088C (en) 2015-10-06
US20180044318A1 (en) 2018-02-15
EP2380887A1 (en) 2011-10-26
US9394274B2 (en) 2016-07-19
CA2612612A1 (en) 2007-01-11
KR20080039392A (ko) 2008-05-07
ECSP088154A (es) 2008-03-26
BRPI0612803A2 (pt) 2012-10-02
HRP20130102T1 (hr) 2013-03-31
US20070004920A1 (en) 2007-01-04
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RS53030B (en) 2014-04-30
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DK1907373T3 (da) 2013-02-04
US20110224440A1 (en) 2011-09-15
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JP2008544993A (ja) 2008-12-11
IL214892A0 (en) 2011-10-31
IL214892A (en) 2013-11-28
PT1907373E (pt) 2013-02-18
MX2007016290A (es) 2008-03-10
PT2380887E (pt) 2013-09-18
NZ565309A (en) 2011-03-31
AU2006265019B2 (en) 2011-10-13
CR9697A (es) 2008-06-26
RS52704B (en) 2013-08-30
US8785644B2 (en) 2014-07-22
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CN101253163B (zh) 2012-05-02

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