MX2015013912A - Metodos y composiciones que utilizan 4-amino-2-(2,6-dioxo-piperidi n-3-il)-isoindolin-1,3-diona para tratamiento y manejo de canceres en el sistema nervioso central. - Google Patents

Metodos y composiciones que utilizan 4-amino-2-(2,6-dioxo-piperidi n-3-il)-isoindolin-1,3-diona para tratamiento y manejo de canceres en el sistema nervioso central.

Info

Publication number
MX2015013912A
MX2015013912A MX2015013912A MX2015013912A MX2015013912A MX 2015013912 A MX2015013912 A MX 2015013912A MX 2015013912 A MX2015013912 A MX 2015013912A MX 2015013912 A MX2015013912 A MX 2015013912A MX 2015013912 A MX2015013912 A MX 2015013912A
Authority
MX
Mexico
Prior art keywords
methods
compositions
isoindoline
dioxo
dione
Prior art date
Application number
MX2015013912A
Other languages
English (en)
Inventor
W Tun Han
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of MX2015013912A publication Critical patent/MX2015013912A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

Se describen métodos y composiciones para tratar, prevenir o manejar cánceres en el sistema nervioso central. El método abarca la administración de 4-amino-2-(2,6-dioxo-piperidin-3-il)-isoindol in-1,3-diona, también conocida como Pomalidomida. Además, se proporcionan en la presente métodos de tratamiento que utilizan este compuesto con quimioterapia, terapia de radiación, terapia hormonal, terapia biológica o inmunoterapia. También se describen composiciones farmacéuticas y formas de dosificación de una sola unidad adecuadas para su uso en los métodos proporcionados en la presente.
MX2015013912A 2013-04-02 2014-04-01 Metodos y composiciones que utilizan 4-amino-2-(2,6-dioxo-piperidi n-3-il)-isoindolin-1,3-diona para tratamiento y manejo de canceres en el sistema nervioso central. MX2015013912A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361807605P 2013-04-02 2013-04-02
PCT/US2014/032483 WO2014165482A1 (en) 2013-04-02 2014-04-01 Methods and compositions using 4-amino-2-(2,6-dioxo-piperidine-3-yl)-isoindoline-1,3-dione for treatment and management of central nervous system cancers

Publications (1)

Publication Number Publication Date
MX2015013912A true MX2015013912A (es) 2016-08-12

Family

ID=50588939

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015013912A MX2015013912A (es) 2013-04-02 2014-04-01 Metodos y composiciones que utilizan 4-amino-2-(2,6-dioxo-piperidi n-3-il)-isoindolin-1,3-diona para tratamiento y manejo de canceres en el sistema nervioso central.

Country Status (14)

Country Link
US (1) US9839632B2 (es)
EP (1) EP2981262A1 (es)
JP (1) JP6469077B2 (es)
KR (1) KR20150136078A (es)
CN (1) CN105246480A (es)
AU (1) AU2014248263A1 (es)
BR (1) BR112015025252A2 (es)
CA (1) CA2907908A1 (es)
EA (1) EA201591902A1 (es)
HK (1) HK1219896A1 (es)
MX (1) MX2015013912A (es)
PH (1) PH12015502266A1 (es)
SG (1) SG11201507759WA (es)
WO (1) WO2014165482A1 (es)

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JP7143295B2 (ja) 2016-11-24 2022-09-28 ティアンジン ヘメイ ファーマスーティカル サイ－テック カンパニー リミテッド ピペリジン－２，６－ジオン誘導体及びクローン病の治療
CN107875128A (zh) * 2017-12-06 2018-04-06 佛山市弘泰药物研发有限公司 一种泊马度胺口崩片及其制备方法
CN111542321A (zh) * 2018-01-02 2020-08-14 细胞基因公司 2-(4-氯苯基)-n-((2-(2,6-二氧代哌啶-3-基)-1-氧代异吲哚啉-5-基)甲基)-2,2-二氟乙酰胺的同位素体
AR119715A1 (es) * 2019-04-12 2022-01-05 Celgene Corp Métodos para tratar linfoma no hodgkin con el uso de 2-(2,6-dioxopiperidin-3-il)-4-((2-fluoro-4-((3-morfolinoazetidin-1-il)metil)bencil)amino)isoindolin-1,3-diona
CA3154510A1 (en) 2019-10-21 2021-04-29 Celgene Corporation Methods of treating chronic lymphocytic leukemia using 2-(2,6-dioxopiperidin-3yl)-4-((2-fluoro-4-((3-morpholinoazetidin-1-yl)methyl)benzyl)amino)isoindoline-1. 3-dione

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Also Published As

Publication number Publication date
US20160045484A1 (en) 2016-02-18
CN105246480A (zh) 2016-01-13
KR20150136078A (ko) 2015-12-04
AU2014248263A1 (en) 2015-10-15
EA201591902A1 (ru) 2016-02-29
JP6469077B2 (ja) 2019-02-13
US9839632B2 (en) 2017-12-12
WO2014165482A1 (en) 2014-10-09
JP2016515621A (ja) 2016-05-30
PH12015502266A1 (en) 2016-02-01
BR112015025252A2 (pt) 2017-07-18
HK1219896A1 (zh) 2017-04-21
CA2907908A1 (en) 2014-10-09
EP2981262A1 (en) 2016-02-10
SG11201507759WA (en) 2015-10-29

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