KR100437981B1 - 벤조피란류및이를함유하는제약조성물 - Google Patents

벤조피란류및이를함유하는제약조성물 Download PDF

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Publication number
KR100437981B1
KR100437981B1 KR1019970708400A KR19970708400A KR100437981B1 KR 100437981 B1 KR100437981 B1 KR 100437981B1 KR 1019970708400 A KR1019970708400 A KR 1019970708400A KR 19970708400 A KR19970708400 A KR 19970708400A KR 100437981 B1 KR100437981 B1 KR 100437981B1
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KR
South Korea
Prior art keywords
benzopyran
dihydro
dimethyl
hydroxy
sulfonamide
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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KR1019970708400A
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English (en)
Korean (ko)
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KR19990021925A (ko
Inventor
폴 더블유. 만레이
Original Assignee
노파르티스 아게
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10774940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR100437981(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 노파르티스 아게 filed Critical 노파르티스 아게
Publication of KR19990021925A publication Critical patent/KR19990021925A/ko
Application granted granted Critical
Publication of KR100437981B1 publication Critical patent/KR100437981B1/ko
Anticipated expiration legal-status Critical
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1019970708400A 1995-05-24 1996-05-24 벤조피란류및이를함유하는제약조성물 Expired - Fee Related KR100437981B1 (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB9510477.4A GB9510477D0 (en) 1995-05-24 1995-05-24 Organic compounds
GB9510477.4 1995-05-24
GB49510477.44 1995-05-24
PCT/EP1996/002257 WO1996037490A1 (en) 1995-05-24 1996-05-24 Benzopyrans and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
KR19990021925A KR19990021925A (ko) 1999-03-25
KR100437981B1 true KR100437981B1 (ko) 2004-07-16

Family

ID=10774940

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019970708400A Expired - Fee Related KR100437981B1 (ko) 1995-05-24 1996-05-24 벤조피란류및이를함유하는제약조성물

Country Status (30)

Country Link
US (1) US5905156A (enExample)
EP (1) EP0828733B1 (enExample)
JP (1) JPH11505820A (enExample)
KR (1) KR100437981B1 (enExample)
CN (1) CN1077888C (enExample)
AR (1) AR004489A1 (enExample)
AT (1) ATE205204T1 (enExample)
AU (1) AU703276B2 (enExample)
BR (1) BR9609048A (enExample)
CA (1) CA2217821C (enExample)
CO (1) CO4700520A1 (enExample)
CZ (1) CZ294474B6 (enExample)
DE (1) DE69615019T2 (enExample)
DK (1) DK0828733T3 (enExample)
ES (1) ES2163634T3 (enExample)
FI (1) FI973992L (enExample)
GB (1) GB9510477D0 (enExample)
HU (1) HU222772B1 (enExample)
IL (1) IL118382A (enExample)
MY (1) MY114924A (enExample)
NO (1) NO314846B1 (enExample)
NZ (1) NZ309765A (enExample)
PL (1) PL184144B1 (enExample)
PT (1) PT828733E (enExample)
RU (1) RU2160735C2 (enExample)
SK (1) SK283215B6 (enExample)
TR (1) TR199701417T1 (enExample)
TW (1) TW421646B (enExample)
WO (1) WO1996037490A1 (enExample)
ZA (1) ZA964209B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972894A (en) * 1997-08-07 1999-10-26 Cytran, Inc. Peptides having potassium channel opener activity
GB9822024D0 (en) * 1998-10-09 1998-12-02 Novartis Ag Organic compounds
GB9909792D0 (en) 1998-12-04 1999-06-23 Cambridge Bioclinical Limited Potassium channel activators and their use
US6384244B2 (en) 2000-05-18 2002-05-07 Merck & Co., Inc. Process for preparing cis- aminochromanols
ZA200501510B (en) * 2002-08-29 2006-10-25 Nissan Chemical Ind Ltd Process for producing aminobenzopyran compound
US7098340B2 (en) * 2003-05-14 2006-08-29 Warner Lambert Company Llc Benzyl sulfonamide derivatives
KR100704009B1 (ko) * 2005-08-30 2007-04-04 한국화학연구원 염증억제 활성을 가지는6-알킬아미노-2-메틸-2'-(ｎ-메틸치환술폰아미도)메틸-2ｈ-1-벤조피란 유도체
BR112018006189A2 (pt) 2015-09-28 2018-10-09 Genentech Inc compostos da fórmula, composição farmacêutica, métodos de tratamento de uma doença, de diminuição do fluxo de íons e de tratamento de prurido em um mamífero, método para tratamento de dores em um mamífero e uso de um composto
CN106008288A (zh) * 2016-06-15 2016-10-12 西北农林科技大学 一种苯磺酰胺类化合物及其用途
JP2020511511A (ja) * 2017-03-24 2020-04-16 ジェネンテック， インコーポレイテッド ナトリウムチャネル阻害剤としての４−ピペリジン−ｎ−（ピリミジン−４−イル）クロマン−７−スルホンアミド誘導体
TW202003490A (zh) 2018-05-22 2020-01-16 瑞士商赫孚孟拉羅股份公司 治療性化合物及其使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4971982A (en) * 1987-07-06 1990-11-20 Hoffmann-La Roche Inc. Benzopyran derivatives
ES2030627A6 (es) * 1990-11-28 1992-11-01 Uriach & Cia Sa J Procedimiento para la obtencion de compuestos benzopiranicos.
GB9102803D0 (en) * 1991-02-11 1991-03-27 Ici Plc Pyridine compounds
KR950009863B1 (ko) * 1991-05-22 1995-08-29 재단법인한국화학연구소 벤조피란 유도체와 그의 제조방법
TW244350B (enExample) * 1991-12-14 1995-04-01 Hoechst Ag
US5236935A (en) * 1992-05-21 1993-08-17 Korea Research Institute Of Chemical Technology Benzopyran derivatives and processes for the preparation thereof

Also Published As

Publication number Publication date
EP0828733B1 (en) 2001-09-05
CA2217821A1 (en) 1996-11-28
JPH11505820A (ja) 1999-05-25
NO975365D0 (no) 1997-11-21
HU222772B1 (hu) 2003-10-28
CO4700520A1 (es) 1998-12-29
AU703276B2 (en) 1999-03-25
NO314846B1 (no) 2003-06-02
EP0828733A1 (en) 1998-03-18
TW421646B (en) 2001-02-11
SK157797A3 (en) 1998-05-06
KR19990021925A (ko) 1999-03-25
BR9609048A (pt) 1999-02-23
CN1185153A (zh) 1998-06-17
MY114924A (en) 2003-02-28
FI973992A0 (fi) 1997-10-17
CA2217821C (en) 2008-05-06
AU6000896A (en) 1996-12-11
TR199701417T1 (xx) 1998-02-21
CN1077888C (zh) 2002-01-16
HK1014137A1 (en) 1999-09-24
FI973992A7 (fi) 1997-12-09
CZ294474B6 (cs) 2005-01-12
GB9510477D0 (en) 1995-07-19
WO1996037490A1 (en) 1996-11-28
CZ368897A3 (cs) 1998-02-18
SK283215B6 (sk) 2003-03-04
ES2163634T3 (es) 2002-02-01
NZ309765A (en) 2000-01-28
IL118382A (en) 2000-01-31
HUP9801751A2 (hu) 1999-06-28
NO975365L (no) 1998-01-15
ZA964209B (en) 1997-11-24
DK0828733T3 (da) 2001-12-17
DE69615019D1 (de) 2001-10-11
MX9709004A (es) 1998-03-31
DE69615019T2 (de) 2002-06-06
IL118382A0 (en) 1996-09-12
PL184144B1 (pl) 2002-09-30
RU2160735C2 (ru) 2000-12-20
US5905156A (en) 1999-05-18
HUP9801751A3 (en) 1999-08-30
AR004489A1 (es) 1998-12-16
FI973992L (fi) 1997-12-09
PL324042A1 (en) 1998-05-11
ATE205204T1 (de) 2001-09-15
PT828733E (pt) 2002-02-28

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