DE69615019T2 - Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen - Google Patents

Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen

Info

Publication number
DE69615019T2
DE69615019T2 DE69615019T DE69615019T DE69615019T2 DE 69615019 T2 DE69615019 T2 DE 69615019T2 DE 69615019 T DE69615019 T DE 69615019T DE 69615019 T DE69615019 T DE 69615019T DE 69615019 T2 DE69615019 T2 DE 69615019T2
Authority
DE
Germany
Prior art keywords
benzopyran
dihydro
dimethyl
hydroxy
trans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69615019T
Other languages
German (de)
English (en)
Other versions
DE69615019D1 (de
Inventor
W. Manley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis Pharma GmbH Austria
Novartis AG
Original Assignee
Novartis Erfindungen Verwaltungs GmbH
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10774940&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69615019(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Erfindungen Verwaltungs GmbH, Novartis AG filed Critical Novartis Erfindungen Verwaltungs GmbH
Publication of DE69615019D1 publication Critical patent/DE69615019D1/de
Application granted granted Critical
Publication of DE69615019T2 publication Critical patent/DE69615019T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69615019T 1995-05-24 1996-05-24 Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen Expired - Lifetime DE69615019T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9510477.4A GB9510477D0 (en) 1995-05-24 1995-05-24 Organic compounds
PCT/EP1996/002257 WO1996037490A1 (en) 1995-05-24 1996-05-24 Benzopyrans and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
DE69615019D1 DE69615019D1 (de) 2001-10-11
DE69615019T2 true DE69615019T2 (de) 2002-06-06

Family

ID=10774940

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69615019T Expired - Lifetime DE69615019T2 (de) 1995-05-24 1996-05-24 Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen

Country Status (30)

Country Link
US (1) US5905156A (enExample)
EP (1) EP0828733B1 (enExample)
JP (1) JPH11505820A (enExample)
KR (1) KR100437981B1 (enExample)
CN (1) CN1077888C (enExample)
AR (1) AR004489A1 (enExample)
AT (1) ATE205204T1 (enExample)
AU (1) AU703276B2 (enExample)
BR (1) BR9609048A (enExample)
CA (1) CA2217821C (enExample)
CO (1) CO4700520A1 (enExample)
CZ (1) CZ294474B6 (enExample)
DE (1) DE69615019T2 (enExample)
DK (1) DK0828733T3 (enExample)
ES (1) ES2163634T3 (enExample)
FI (1) FI973992L (enExample)
GB (1) GB9510477D0 (enExample)
HU (1) HU222772B1 (enExample)
IL (1) IL118382A (enExample)
MY (1) MY114924A (enExample)
NO (1) NO314846B1 (enExample)
NZ (1) NZ309765A (enExample)
PL (1) PL184144B1 (enExample)
PT (1) PT828733E (enExample)
RU (1) RU2160735C2 (enExample)
SK (1) SK283215B6 (enExample)
TR (1) TR199701417T1 (enExample)
TW (1) TW421646B (enExample)
WO (1) WO1996037490A1 (enExample)
ZA (1) ZA964209B (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5972894A (en) * 1997-08-07 1999-10-26 Cytran, Inc. Peptides having potassium channel opener activity
GB9822024D0 (en) * 1998-10-09 1998-12-02 Novartis Ag Organic compounds
GB9909792D0 (en) 1998-12-04 1999-06-23 Cambridge Bioclinical Limited Potassium channel activators and their use
US6384244B2 (en) 2000-05-18 2002-05-07 Merck & Co., Inc. Process for preparing cis- aminochromanols
ZA200501510B (en) * 2002-08-29 2006-10-25 Nissan Chemical Ind Ltd Process for producing aminobenzopyran compound
US7098340B2 (en) * 2003-05-14 2006-08-29 Warner Lambert Company Llc Benzyl sulfonamide derivatives
KR100704009B1 (ko) * 2005-08-30 2007-04-04 한국화학연구원 염증억제 활성을 가지는6-알킬아미노-2-메틸-2'-(n-메틸치환술폰아미도)메틸-2h-1-벤조피란 유도체
BR112018006189A2 (pt) 2015-09-28 2018-10-09 Genentech Inc compostos da fórmula, composição farmacêutica, métodos de tratamento de uma doença, de diminuição do fluxo de íons e de tratamento de prurido em um mamífero, método para tratamento de dores em um mamífero e uso de um composto
CN106008288A (zh) * 2016-06-15 2016-10-12 西北农林科技大学 一种苯磺酰胺类化合物及其用途
JP2020511511A (ja) * 2017-03-24 2020-04-16 ジェネンテック, インコーポレイテッド ナトリウムチャネル阻害剤としての4−ピペリジン−n−(ピリミジン−4−イル)クロマン−7−スルホンアミド誘導体
TW202003490A (zh) 2018-05-22 2020-01-16 瑞士商赫孚孟拉羅股份公司 治療性化合物及其使用方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4971982A (en) * 1987-07-06 1990-11-20 Hoffmann-La Roche Inc. Benzopyran derivatives
ES2030627A6 (es) * 1990-11-28 1992-11-01 Uriach & Cia Sa J Procedimiento para la obtencion de compuestos benzopiranicos.
GB9102803D0 (en) * 1991-02-11 1991-03-27 Ici Plc Pyridine compounds
KR950009863B1 (ko) * 1991-05-22 1995-08-29 재단법인한국화학연구소 벤조피란 유도체와 그의 제조방법
TW244350B (enExample) * 1991-12-14 1995-04-01 Hoechst Ag
US5236935A (en) * 1992-05-21 1993-08-17 Korea Research Institute Of Chemical Technology Benzopyran derivatives and processes for the preparation thereof

Also Published As

Publication number Publication date
EP0828733B1 (en) 2001-09-05
CA2217821A1 (en) 1996-11-28
JPH11505820A (ja) 1999-05-25
NO975365D0 (no) 1997-11-21
HU222772B1 (hu) 2003-10-28
CO4700520A1 (es) 1998-12-29
AU703276B2 (en) 1999-03-25
NO314846B1 (no) 2003-06-02
EP0828733A1 (en) 1998-03-18
TW421646B (en) 2001-02-11
SK157797A3 (en) 1998-05-06
KR19990021925A (ko) 1999-03-25
BR9609048A (pt) 1999-02-23
CN1185153A (zh) 1998-06-17
MY114924A (en) 2003-02-28
FI973992A0 (fi) 1997-10-17
CA2217821C (en) 2008-05-06
AU6000896A (en) 1996-12-11
TR199701417T1 (xx) 1998-02-21
CN1077888C (zh) 2002-01-16
HK1014137A1 (en) 1999-09-24
FI973992A7 (fi) 1997-12-09
CZ294474B6 (cs) 2005-01-12
GB9510477D0 (en) 1995-07-19
WO1996037490A1 (en) 1996-11-28
CZ368897A3 (cs) 1998-02-18
SK283215B6 (sk) 2003-03-04
ES2163634T3 (es) 2002-02-01
NZ309765A (en) 2000-01-28
IL118382A (en) 2000-01-31
HUP9801751A2 (hu) 1999-06-28
NO975365L (no) 1998-01-15
KR100437981B1 (ko) 2004-07-16
ZA964209B (en) 1997-11-24
DK0828733T3 (da) 2001-12-17
DE69615019D1 (de) 2001-10-11
MX9709004A (es) 1998-03-31
IL118382A0 (en) 1996-09-12
PL184144B1 (pl) 2002-09-30
RU2160735C2 (ru) 2000-12-20
US5905156A (en) 1999-05-18
HUP9801751A3 (en) 1999-08-30
AR004489A1 (es) 1998-12-16
FI973992L (fi) 1997-12-09
PL324042A1 (en) 1998-05-11
ATE205204T1 (de) 2001-09-15
PT828733E (pt) 2002-02-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336

8328 Change in the person/name/address of the agent

Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN