JPS5686188A - 7-acylamino-3-substituted cephalosporanic acid derivative and its preparation - Google Patents
7-acylamino-3-substituted cephalosporanic acid derivative and its preparationInfo
- Publication number
- JPS5686188A JPS5686188A JP16399080A JP16399080A JPS5686188A JP S5686188 A JPS5686188 A JP S5686188A JP 16399080 A JP16399080 A JP 16399080A JP 16399080 A JP16399080 A JP 16399080A JP S5686188 A JPS5686188 A JP S5686188A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- salt
- acylamino
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- YGBFLZPYDUKSPT-MRVPVSSYSA-N cephalosporanic acid Chemical class S1CC(COC(=O)C)=C(C(O)=O)N2C(=O)C[C@H]21 YGBFLZPYDUKSPT-MRVPVSSYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- UDKPLEHAUXKWLH-WCRCJTMVSA-N (6R)-7-[[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(methylsulfanylmethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid Chemical compound CSCC=1CS[C@H]2N(C=1C(=O)O)C(C2NC(C(=NOC)C=1N=C(SC=1)N)=O)=O UDKPLEHAUXKWLH-WCRCJTMVSA-N 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 125000004849 alkoxymethyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 244000000010 microbial pathogen Species 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
Landscapes
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7939985 | 1979-11-19 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP19117582A Division JPS5896092A (ja) | 1979-11-19 | 1982-10-29 | 7−アシルアミノ−3−置換セフアロスポラン酸誘導体およびその製造法 |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5686188A true JPS5686188A (en) | 1981-07-13 |
Family
ID=10509300
Family Applications (12)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16399080A Pending JPS5686188A (en) | 1979-11-19 | 1980-11-19 | 7-acylamino-3-substituted cephalosporanic acid derivative and its preparation |
JP16398980A Granted JPS5686187A (en) | 1979-11-19 | 1980-11-19 | 7-acylamino-3-vinylcephalosporanic acid derivative and its preparation |
JP19117582A Granted JPS5896092A (ja) | 1979-11-19 | 1982-10-29 | 7−アシルアミノ−3−置換セフアロスポラン酸誘導体およびその製造法 |
JP22640283A Granted JPS59144788A (ja) | 1979-11-19 | 1983-11-29 | 7−アシルアミノ−3−置換セフアロスポラン酸誘導体およびその製法 |
JP27813884A Pending JPS60185787A (ja) | 1979-11-19 | 1984-12-29 | 7−アシルアミノ−3−置換セフアロスポラン酸誘導体およびその製造方法 |
JP62044400A Granted JPS62277391A (ja) | 1979-11-19 | 1987-02-26 | 7−アシルアミノ−3−ビニルセフアロスポラン酸誘導体およびその製法 |
JP29025087A Granted JPS63152385A (ja) | 1979-11-19 | 1987-11-17 | 新規な7−置換−3−ビニルセファロスポラン酸 |
JP62290253A Granted JPS63146863A (ja) | 1979-11-19 | 1987-11-17 | カルボン酸類 |
JP29024887A Granted JPS63152387A (ja) | 1979-11-19 | 1987-11-17 | 7−アシルアミノ−3−ビニル セファロスポラン酸誘導体 |
JP62290251A Granted JPS63152370A (ja) | 1979-11-19 | 1987-11-17 | 新規カルボン酸 |
JP29024987A Granted JPS63152388A (ja) | 1979-11-19 | 1987-11-17 | 新規なセフェム化合物 |
JP62290252A Granted JPS63152371A (ja) | 1979-11-19 | 1987-11-17 | アミノチアゾール誘導体 |
Family Applications After (11)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16398980A Granted JPS5686187A (en) | 1979-11-19 | 1980-11-19 | 7-acylamino-3-vinylcephalosporanic acid derivative and its preparation |
JP19117582A Granted JPS5896092A (ja) | 1979-11-19 | 1982-10-29 | 7−アシルアミノ−3−置換セフアロスポラン酸誘導体およびその製造法 |
JP22640283A Granted JPS59144788A (ja) | 1979-11-19 | 1983-11-29 | 7−アシルアミノ−3−置換セフアロスポラン酸誘導体およびその製法 |
JP27813884A Pending JPS60185787A (ja) | 1979-11-19 | 1984-12-29 | 7−アシルアミノ−3−置換セフアロスポラン酸誘導体およびその製造方法 |
JP62044400A Granted JPS62277391A (ja) | 1979-11-19 | 1987-02-26 | 7−アシルアミノ−3−ビニルセフアロスポラン酸誘導体およびその製法 |
JP29025087A Granted JPS63152385A (ja) | 1979-11-19 | 1987-11-17 | 新規な7−置換−3−ビニルセファロスポラン酸 |
JP62290253A Granted JPS63146863A (ja) | 1979-11-19 | 1987-11-17 | カルボン酸類 |
JP29024887A Granted JPS63152387A (ja) | 1979-11-19 | 1987-11-17 | 7−アシルアミノ−3−ビニル セファロスポラン酸誘導体 |
JP62290251A Granted JPS63152370A (ja) | 1979-11-19 | 1987-11-17 | 新規カルボン酸 |
JP29024987A Granted JPS63152388A (ja) | 1979-11-19 | 1987-11-17 | 新規なセフェム化合物 |
JP62290252A Granted JPS63152371A (ja) | 1979-11-19 | 1987-11-17 | アミノチアゾール誘導体 |
Country Status (2)
Country | Link |
---|---|
JP (12) | JPS5686188A (enrdf_load_stackoverflow) |
ZA (1) | ZA806977B (enrdf_load_stackoverflow) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56128786A (en) * | 1980-02-18 | 1981-10-08 | Roussel Uclaf | Novel oxime derivatives of 3-alkyloxy or 3-alkylthiomethyl-7-aminothiazolylacetamidocephalosporanic acid, their manufacture, their use as drug, drug containing them and novel intermediate |
WO1984004747A1 (en) * | 1983-03-02 | 1984-12-06 | Kyoto Pharma Ind | Cephem compounds |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4464369A (en) * | 1977-03-14 | 1984-08-07 | Fujisawa Pharmaceutical Co., Ltd. | 7-Acylamino-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions |
ZA806977B (en) * | 1979-11-19 | 1981-10-28 | Fujisawa Pharmaceutical Co | 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
EP0156118A1 (en) * | 1980-08-29 | 1985-10-02 | Fujisawa Pharmaceutical Co., Ltd. | New starting compounds for the preparation of cephem compounds and processes for preparation thereof |
JPS6052754B2 (ja) * | 1981-01-29 | 1985-11-21 | 山之内製薬株式会社 | 7−アミノ−3−ハロゲノメチル−△↑3−セフェム−4−カルボン酸類およびその製法 |
JPS58135894A (ja) * | 1982-01-22 | 1983-08-12 | Fujisawa Pharmaceut Co Ltd | 7―置換ブチルアミド―3―ビニルセファロスポラン酸誘導体 |
JPS5921695A (ja) * | 1982-07-29 | 1984-02-03 | Dai Ichi Seiyaku Co Ltd | セフアロスポリン誘導体 |
ZA836918B (en) * | 1982-09-30 | 1984-05-30 | Fujisawa Pharmaceutical Co | 7-substituted-3-vinyl-3-cephem compounds and processes for the production of the same |
DK162718C (da) * | 1982-09-30 | 1992-05-11 | Fujisawa Pharmaceutical Co | Analogifremgangsmaade til fremstilling af 7-substitueret-3-vinyl-3-cephemforbindelser |
JPS59210092A (ja) * | 1983-05-13 | 1984-11-28 | Dai Ichi Seiyaku Co Ltd | セフアロスポリン誘導体 |
GB8318846D0 (en) * | 1983-07-12 | 1983-08-10 | Fujisawa Pharmaceutical Co | Prophylactic/therapeutic agent against fish diseases |
GB8329030D0 (en) * | 1983-10-31 | 1983-11-30 | Fujisawa Pharmaceutical Co | Cephem compounds |
DE3775798D1 (de) | 1986-03-19 | 1992-02-20 | Banyu Pharma Co Ltd | Cephalosporinverbindungen, verfahren zu ihrer herstellung und antibakterielle mittel. |
US4822786A (en) * | 1986-07-01 | 1989-04-18 | Kaken Pharmaceutical Co., Ltd. | Cephalosporin compounds, and antibacterial agents |
JP4157177B2 (ja) * | 1997-06-04 | 2008-09-24 | 大塚化学ホールディングス株式会社 | 3−アルケニルセフェム化合物の製造法 |
AT406773B (de) * | 1998-04-02 | 2000-08-25 | Biochemie Gmbh | Neues salz von 7-(2-(aminothiazol-4yl)-2- |
ITMI20022076A1 (it) * | 2002-10-01 | 2004-04-02 | Antibioticos Spa | Sali di intermedi del cefdinir. |
US7980324B2 (en) | 2006-02-03 | 2011-07-19 | Black & Decker Inc. | Housing and gearbox for drill or driver |
JP4779741B2 (ja) * | 2006-03-22 | 2011-09-28 | 株式会社日立製作所 | ヒートポンプシステム,ヒートポンプシステムの軸封方法,ヒートポンプシステムの改造方法 |
UY34585A (es) * | 2012-01-24 | 2013-09-02 | Aicuris Gmbh & Co Kg | Compuestos b-lactámicos sustituidos con amidina, su preparación y uso |
KR101485316B1 (ko) * | 2014-04-16 | 2015-01-22 | (주)에이치티씨 | 플렛 케이블용 컨넥터 핀 자동 압착장치 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1325846A (en) * | 1972-02-23 | 1973-08-08 | Lilly Co Eli | Process for the preparation of a 3-thiomethyl cephalosporin |
DE2209019A1 (de) * | 1972-02-25 | 1973-08-30 | Lilly Co Eli | Verfahren zur herstellung von 3-thiomethylcephalosporinverbindungen |
JPS50100076A (enrdf_load_stackoverflow) * | 1974-01-14 | 1975-08-08 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE789817A (fr) * | 1971-10-07 | 1973-04-06 | Glaxo Lab Ltd | Perfectionnements aux composes de cephalosporine |
DE2710902A1 (de) * | 1977-03-12 | 1978-09-21 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
US4200745A (en) * | 1977-12-20 | 1980-04-29 | Eli Lilly And Company | 7[2-(2-Aminothiazol-4-yl)-2-alkoxyimino]acetamido 3[4-alkyl-5-oxo-6-hydroxy-3,4 dihydro 1,2,4-triazin 3-yl]thio methyl cephalosporins |
FR2432521A1 (fr) * | 1978-03-31 | 1980-02-29 | Roussel Uclaf | Nouvelles oximes o-substituees derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
GB1604723A (en) * | 1978-05-26 | 1981-12-16 | Glaxo Operations Ltd | 7-(2-aminothiazol-4-yl)-2-oxyimino-acetamido)-cephem derivatives |
KR830000606B1 (ko) * | 1978-05-26 | 1983-03-17 | 헤롤드 월터 마틴 | 세팔로스포린 항생제의 제조방법 |
JPS5559197A (en) * | 1978-10-27 | 1980-05-02 | Glaxo Group Ltd | Novel cephalosporin compound |
BE879664A (fr) * | 1978-10-27 | 1980-04-28 | Glaxo Group Ltd | Nouvelles cephalosporines, leur preparation et compositions les contenant |
BE880037A (fr) * | 1978-11-15 | 1980-05-14 | Glaxo Group Ltd | Cephalosporines a activite antibiotique et procede de preparation |
BE880068A (fr) * | 1978-11-17 | 1980-05-16 | Glaxo Group Ltd | Nouvelles cephalosporines et leur preparation |
ZA801011B (en) * | 1979-02-23 | 1981-04-29 | Glaxo Group Ltd | Cephalosporin antibiotics |
JPS55124790A (en) * | 1979-03-19 | 1980-09-26 | Sankyo Co Ltd | Cephem compound, its preparation and antimicrobials consisting the same mainly |
NL160860B (nl) * | 1979-03-22 | American Cyanamid Co | Werkwijze voor het bereiden van een vulcaniseerbaar mengsel. | |
ZA806977B (en) * | 1979-11-19 | 1981-10-28 | Fujisawa Pharmaceutical Co | 7-acylamino-3-vinylcephalosporanic acid derivatives and processes for the preparation thereof |
-
1980
- 1980-11-11 ZA ZA00806977A patent/ZA806977B/xx unknown
- 1980-11-19 JP JP16399080A patent/JPS5686188A/ja active Pending
- 1980-11-19 JP JP16398980A patent/JPS5686187A/ja active Granted
-
1982
- 1982-10-29 JP JP19117582A patent/JPS5896092A/ja active Granted
-
1983
- 1983-11-29 JP JP22640283A patent/JPS59144788A/ja active Granted
-
1984
- 1984-12-29 JP JP27813884A patent/JPS60185787A/ja active Pending
-
1987
- 1987-02-26 JP JP62044400A patent/JPS62277391A/ja active Granted
- 1987-11-17 JP JP29025087A patent/JPS63152385A/ja active Granted
- 1987-11-17 JP JP62290253A patent/JPS63146863A/ja active Granted
- 1987-11-17 JP JP29024887A patent/JPS63152387A/ja active Granted
- 1987-11-17 JP JP62290251A patent/JPS63152370A/ja active Granted
- 1987-11-17 JP JP29024987A patent/JPS63152388A/ja active Granted
- 1987-11-17 JP JP62290252A patent/JPS63152371A/ja active Granted
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1325846A (en) * | 1972-02-23 | 1973-08-08 | Lilly Co Eli | Process for the preparation of a 3-thiomethyl cephalosporin |
DE2209019A1 (de) * | 1972-02-25 | 1973-08-30 | Lilly Co Eli | Verfahren zur herstellung von 3-thiomethylcephalosporinverbindungen |
JPS50100076A (enrdf_load_stackoverflow) * | 1974-01-14 | 1975-08-08 |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56128786A (en) * | 1980-02-18 | 1981-10-08 | Roussel Uclaf | Novel oxime derivatives of 3-alkyloxy or 3-alkylthiomethyl-7-aminothiazolylacetamidocephalosporanic acid, their manufacture, their use as drug, drug containing them and novel intermediate |
JPS58170789A (ja) * | 1980-02-18 | 1983-10-07 | ルセル−ユクラフ | 3−アルキルオキシ又は3−アルキルチオメチル−7−アミノチアゾリルアセトアミドセフアロスポラン酸の新規なオキシム誘導体、それらの製造、薬剤としての使用、それらを含む薬剤並びに得られる新規な中間体 |
JPS6452784A (en) * | 1980-02-18 | 1989-02-28 | Roussel Uclaf | Novel oxime derivative of 3-alkyloxy or 3-alkylthiomethyl-7-aminothiazolylacetamido cephalosporanic acid |
WO1984004747A1 (en) * | 1983-03-02 | 1984-12-06 | Kyoto Pharma Ind | Cephem compounds |
Also Published As
Publication number | Publication date |
---|---|
JPS5686187A (en) | 1981-07-13 |
JPH0215556B2 (enrdf_load_stackoverflow) | 1990-04-12 |
JPS60185787A (ja) | 1985-09-21 |
JPS63152385A (ja) | 1988-06-24 |
JPS63152387A (ja) | 1988-06-24 |
JPS63152370A (ja) | 1988-06-24 |
JPS63152388A (ja) | 1988-06-24 |
JPH0219828B2 (enrdf_load_stackoverflow) | 1990-05-07 |
ZA806977B (en) | 1981-10-28 |
JPH0338278B2 (enrdf_load_stackoverflow) | 1991-06-10 |
JPS6320435B2 (enrdf_load_stackoverflow) | 1988-04-27 |
JPS63152371A (ja) | 1988-06-24 |
JPS6238357B2 (enrdf_load_stackoverflow) | 1987-08-17 |
JPS63146863A (ja) | 1988-06-18 |
JPH0333712B2 (enrdf_load_stackoverflow) | 1991-05-20 |
JPH0338277B2 (enrdf_load_stackoverflow) | 1991-06-10 |
JPH0225905B2 (enrdf_load_stackoverflow) | 1990-06-06 |
JPH0314832B2 (enrdf_load_stackoverflow) | 1991-02-27 |
JPS5896092A (ja) | 1983-06-07 |
JPS59144788A (ja) | 1984-08-18 |
JPS62277391A (ja) | 1987-12-02 |
JPH0369353B2 (enrdf_load_stackoverflow) | 1991-10-31 |
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