JPH11140085A5 - - Google Patents

Info

Publication number
JPH11140085A5
JPH11140085A5 JP1997319182A JP31918297A JPH11140085A5 JP H11140085 A5 JPH11140085 A5 JP H11140085A5 JP 1997319182 A JP1997319182 A JP 1997319182A JP 31918297 A JP31918297 A JP 31918297A JP H11140085 A5 JPH11140085 A5 JP H11140085A5
Authority
JP
Japan
Prior art keywords
och
ethylamide
dimethylamino
ethyl
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997319182A
Other languages
English (en)
Japanese (ja)
Other versions
JPH11140085A (ja
JP4094710B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from JP31918297A external-priority patent/JP4094710B2/ja
Priority to JP31918297A priority Critical patent/JP4094710B2/ja
Priority to US09/530,828 priority patent/US6310210B1/en
Priority to EP98951712A priority patent/EP1029863B1/en
Priority to PT98951712T priority patent/PT1029863E/pt
Priority to AT98951712T priority patent/ATE240330T1/de
Priority to BR9813972-0A priority patent/BR9813972A/pt
Priority to CA002309196A priority patent/CA2309196C/en
Priority to ES98951712T priority patent/ES2193574T3/es
Priority to AU97619/98A priority patent/AU738823B2/en
Priority to CN98810870A priority patent/CN1114605C/zh
Priority to EA200000491A priority patent/EA002211B1/ru
Priority to DE69814667T priority patent/DE69814667T2/de
Priority to PCT/JP1998/005000 priority patent/WO1999024430A1/ja
Priority to KR1020007004645A priority patent/KR100563210B1/ko
Priority to DK98951712T priority patent/DK1029863T3/da
Publication of JPH11140085A publication Critical patent/JPH11140085A/ja
Publication of JPH11140085A5 publication Critical patent/JPH11140085A5/ja
Publication of JP4094710B2 publication Critical patent/JP4094710B2/ja
Application granted granted Critical
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP31918297A 1997-11-06 1997-11-06 新規なカンプトテシン誘導体 Expired - Fee Related JP4094710B2 (ja)

Priority Applications (15)

Application Number Priority Date Filing Date Title
JP31918297A JP4094710B2 (ja) 1997-11-06 1997-11-06 新規なカンプトテシン誘導体
AU97619/98A AU738823B2 (en) 1997-11-06 1998-11-06 New camptothecin derivatives
EA200000491A EA002211B1 (ru) 1997-11-06 1998-11-06 Новые производные камптотецина
PT98951712T PT1029863E (pt) 1997-11-06 1998-11-06 Derivados de camptotecina
AT98951712T ATE240330T1 (de) 1997-11-06 1998-11-06 Camptothecin-derivate
BR9813972-0A BR9813972A (pt) 1997-11-06 1998-11-06 Derivados de camptotecina
CA002309196A CA2309196C (en) 1997-11-06 1998-11-06 Novel camptothecin derivatives
ES98951712T ES2193574T3 (es) 1997-11-06 1998-11-06 Deriados de camptotecina.
US09/530,828 US6310210B1 (en) 1997-11-06 1998-11-06 Camptothecin derivatives
CN98810870A CN1114605C (zh) 1997-11-06 1998-11-06 新型喜树碱衍生物
EP98951712A EP1029863B1 (en) 1997-11-06 1998-11-06 Camptothecin derivatives
DE69814667T DE69814667T2 (de) 1997-11-06 1998-11-06 Camptothecin-derivate
PCT/JP1998/005000 WO1999024430A1 (en) 1997-11-06 1998-11-06 Novel camptothecin derivatives
KR1020007004645A KR100563210B1 (ko) 1997-11-06 1998-11-06 신규한 캄프토테신 유도체
DK98951712T DK1029863T3 (da) 1997-11-06 1998-11-06 Camptothecinderivater

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31918297A JP4094710B2 (ja) 1997-11-06 1997-11-06 新規なカンプトテシン誘導体

Publications (3)

Publication Number Publication Date
JPH11140085A JPH11140085A (ja) 1999-05-25
JPH11140085A5 true JPH11140085A5 (https=) 2005-01-06
JP4094710B2 JP4094710B2 (ja) 2008-06-04

Family

ID=18107341

Family Applications (1)

Application Number Title Priority Date Filing Date
JP31918297A Expired - Fee Related JP4094710B2 (ja) 1997-11-06 1997-11-06 新規なカンプトテシン誘導体

Country Status (15)

Country Link
US (1) US6310210B1 (https=)
EP (1) EP1029863B1 (https=)
JP (1) JP4094710B2 (https=)
KR (1) KR100563210B1 (https=)
CN (1) CN1114605C (https=)
AT (1) ATE240330T1 (https=)
AU (1) AU738823B2 (https=)
BR (1) BR9813972A (https=)
CA (1) CA2309196C (https=)
DE (1) DE69814667T2 (https=)
DK (1) DK1029863T3 (https=)
EA (1) EA002211B1 (https=)
ES (1) ES2193574T3 (https=)
PT (1) PT1029863E (https=)
WO (1) WO1999024430A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR027687A1 (es) 2000-03-22 2003-04-09 Yakult Honsha Kk Procedimiento para preparar camptotecina
EP1430059B1 (en) 2001-09-25 2006-03-01 Dr. Reddy's Laboratories Ltd. Pharmaceutically acceptable salts of 20(s)-camptothecins
WO2003033525A1 (en) * 2001-10-12 2003-04-24 Debio Recherche Pharmacuetique S.A. Amino-substituted camptothecin polymer derivatives and use of the same for the manufacture of a medicament
US6608076B1 (en) * 2002-05-16 2003-08-19 Enzon, Inc. Camptothecin derivatives and polymeric conjugates thereof
CA2508831C (en) * 2002-12-13 2012-05-01 Immunomedics, Inc. Immunoconjugates with an intracellularly-cleavable linkage
US20040204435A1 (en) * 2003-04-09 2004-10-14 Joachim Liehr Alternating treatment with topoisomerase I and topoisomerase II inhibitors
CZ299329B6 (cs) * 2003-08-26 2008-06-18 Pliva-Lachema A.S. Zpusob výroby 7-ethyl-10-[ 4-(1-piperidino)-1-piperidino]karbonyloxykamptothecinu
CZ299593B6 (cs) * 2003-12-16 2008-09-10 Pliva-Lachema A. S. Zpusob výroby 7-ethyl-10-hydroxykamptothecinu
DE602005024923D1 (de) * 2004-02-13 2011-01-05 Yakult Honsha Kk Wässrige lösung mit einem camptothecin

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58134095A (ja) 1982-02-05 1983-08-10 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体
US4473692A (en) 1981-09-04 1984-09-25 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
JPS5839684A (ja) 1981-09-04 1983-03-08 Yakult Honsha Co Ltd １０−置換カンプテシン誘導体の製造法
JPS5951287A (ja) 1982-09-17 1984-03-24 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体
JPS5951289A (ja) 1982-09-17 1984-03-24 Yakult Honsha Co Ltd 新規な９−置換−カンプトテシン誘導体
US4981968A (en) 1987-03-31 1991-01-01 Research Triangle Institute Synthesis of camptothecin and analogs thereof
US5049668A (en) 1989-09-15 1991-09-17 Research Triangle Institute 10,11-methylenedioxy-20(RS)-camptothecin analogs
US5122606A (en) 1987-04-14 1992-06-16 Research Triangle Institute 10,11-methylenedioxy camptothecins
JP2540357B2 (ja) 1987-06-24 1996-10-02 第一製薬株式会社 六環性化合物
US4939255A (en) 1987-06-24 1990-07-03 Daiichi Pharmaceutical Co., Ltd. Hexa-cyclic camptothecin derivatives
CA1332413C (en) * 1987-06-25 1994-10-11 Kabushiki Kaisha Yakult Honsha Camptothecin derivatives and process for preparing same
JP2538792B2 (ja) 1987-06-25 1996-10-02 株式会社ヤクルト本社 新規なカンプトテシン誘導体
JPH0615547B2 (ja) 1988-01-20 1994-03-02 株式会社ヤクルト本社 新規なカンプトテシン誘導体
WO1991004260A2 (en) 1989-09-15 1991-04-04 Research Triangle Institute 10,11-methylenedioxy-20(rs)-camptothecin and 10,11-methylenedioxy-20(s)-camptothecin analogs
US5162532A (en) 1990-12-20 1992-11-10 North Carolina State University Intermediates and method of making camptothecin and camptothecin analogs
JPH0873461A (ja) * 1994-09-06 1996-03-19 Yakult Honsha Co Ltd 新規なカンプトテシン誘導体、その製造法および抗腫瘍剤

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