DK1029863T3 - Camptothecinderivater - Google Patents
CamptothecinderivaterInfo
- Publication number
- DK1029863T3 DK1029863T3 DK98951712T DK98951712T DK1029863T3 DK 1029863 T3 DK1029863 T3 DK 1029863T3 DK 98951712 T DK98951712 T DK 98951712T DK 98951712 T DK98951712 T DK 98951712T DK 1029863 T3 DK1029863 T3 DK 1029863T3
- Authority
- DK
- Denmark
- Prior art keywords
- salts
- carbon atoms
- lower alkylamino
- alkoxyl
- group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP31918297A JP4094710B2 (ja) | 1997-11-06 | 1997-11-06 | 新規なカンプトテシン誘導体 |
| PCT/JP1998/005000 WO1999024430A1 (fr) | 1997-11-06 | 1998-11-06 | Nouveaux derives de la camptothecine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1029863T3 true DK1029863T3 (da) | 2003-08-11 |
Family
ID=18107341
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98951712T DK1029863T3 (da) | 1997-11-06 | 1998-11-06 | Camptothecinderivater |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6310210B1 (da) |
| EP (1) | EP1029863B1 (da) |
| JP (1) | JP4094710B2 (da) |
| KR (1) | KR100563210B1 (da) |
| CN (1) | CN1114605C (da) |
| AT (1) | ATE240330T1 (da) |
| AU (1) | AU738823B2 (da) |
| BR (1) | BR9813972A (da) |
| CA (1) | CA2309196C (da) |
| DE (1) | DE69814667T2 (da) |
| DK (1) | DK1029863T3 (da) |
| EA (1) | EA002211B1 (da) |
| ES (1) | ES2193574T3 (da) |
| PT (1) | PT1029863E (da) |
| WO (1) | WO1999024430A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR027687A1 (es) | 2000-03-22 | 2003-04-09 | Yakult Honsha Kk | Procedimiento para preparar camptotecina |
| HUP0401912A3 (en) | 2001-09-25 | 2007-02-28 | Reddys Lab Ltd Dr | Pharmaceutically acceptable salts of 20(s)-camptothecins, process for their preparation and pharmaceutical compositions containing them |
| WO2003033525A1 (en) * | 2001-10-12 | 2003-04-24 | Debio Recherche Pharmacuetique S.A. | Amino-substituted camptothecin polymer derivatives and use of the same for the manufacture of a medicament |
| US6608076B1 (en) | 2002-05-16 | 2003-08-19 | Enzon, Inc. | Camptothecin derivatives and polymeric conjugates thereof |
| EP1572242B1 (en) * | 2002-12-13 | 2014-04-16 | Immunomedics, Inc. | Immunoconjugates with an intracellularly-cleavable linkage |
| US20040204435A1 (en) * | 2003-04-09 | 2004-10-14 | Joachim Liehr | Alternating treatment with topoisomerase I and topoisomerase II inhibitors |
| CZ299329B6 (cs) * | 2003-08-26 | 2008-06-18 | Pliva-Lachema A.S. | Zpusob výroby 7-ethyl-10-[ 4-(1-piperidino)-1-piperidino]karbonyloxykamptothecinu |
| CZ299593B6 (cs) * | 2003-12-16 | 2008-09-10 | Pliva-Lachema A. S. | Zpusob výroby 7-ethyl-10-hydroxykamptothecinu |
| CA2556254A1 (en) * | 2004-02-13 | 2005-08-25 | Kabushiki Kaisha Yakult Honsha | Aqueous solution preparation containing camptothecins |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5839684A (ja) | 1981-09-04 | 1983-03-08 | Yakult Honsha Co Ltd | １０−置換カンプテシン誘導体の製造法 |
| US4473692A (en) | 1981-09-04 | 1984-09-25 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives and process for preparing same |
| JPS58134095A (ja) | 1982-02-05 | 1983-08-10 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| JPS5951289A (ja) | 1982-09-17 | 1984-03-24 | Yakult Honsha Co Ltd | 新規な９−置換−カンプトテシン誘導体 |
| JPS5951287A (ja) | 1982-09-17 | 1984-03-24 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体 |
| US4981968A (en) | 1987-03-31 | 1991-01-01 | Research Triangle Institute | Synthesis of camptothecin and analogs thereof |
| US5049668A (en) | 1989-09-15 | 1991-09-17 | Research Triangle Institute | 10,11-methylenedioxy-20(RS)-camptothecin analogs |
| US5122606A (en) | 1987-04-14 | 1992-06-16 | Research Triangle Institute | 10,11-methylenedioxy camptothecins |
| JP2540357B2 (ja) | 1987-06-24 | 1996-10-02 | 第一製薬株式会社 | 六環性化合物 |
| US4939255A (en) | 1987-06-24 | 1990-07-03 | Daiichi Pharmaceutical Co., Ltd. | Hexa-cyclic camptothecin derivatives |
| CA1332413C (en) * | 1987-06-25 | 1994-10-11 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives and process for preparing same |
| JP2538792B2 (ja) | 1987-06-25 | 1996-10-02 | 株式会社ヤクルト本社 | 新規なカンプトテシン誘導体 |
| JPH0615547B2 (ja) | 1988-01-20 | 1994-03-02 | 株式会社ヤクルト本社 | 新規なカンプトテシン誘導体 |
| WO1991004260A2 (en) | 1989-09-15 | 1991-04-04 | Research Triangle Institute | 10,11-methylenedioxy-20(rs)-camptothecin and 10,11-methylenedioxy-20(s)-camptothecin analogs |
| US5162532A (en) | 1990-12-20 | 1992-11-10 | North Carolina State University | Intermediates and method of making camptothecin and camptothecin analogs |
| JPH0873461A (ja) * | 1994-09-06 | 1996-03-19 | Yakult Honsha Co Ltd | 新規なカンプトテシン誘導体、その製造法および抗腫瘍剤 |
-
1997
- 1997-11-06 JP JP31918297A patent/JP4094710B2/ja not_active Expired - Fee Related
-
1998
- 1998-11-06 EP EP98951712A patent/EP1029863B1/en not_active Expired - Lifetime
- 1998-11-06 KR KR1020007004645A patent/KR100563210B1/ko not_active IP Right Cessation
- 1998-11-06 DK DK98951712T patent/DK1029863T3/da active
- 1998-11-06 CA CA002309196A patent/CA2309196C/en not_active Expired - Fee Related
- 1998-11-06 BR BR9813972-0A patent/BR9813972A/pt active Search and Examination
- 1998-11-06 PT PT98951712T patent/PT1029863E/pt unknown
- 1998-11-06 AU AU97619/98A patent/AU738823B2/en not_active Ceased
- 1998-11-06 AT AT98951712T patent/ATE240330T1/de active
- 1998-11-06 ES ES98951712T patent/ES2193574T3/es not_active Expired - Lifetime
- 1998-11-06 WO PCT/JP1998/005000 patent/WO1999024430A1/ja not_active Application Discontinuation
- 1998-11-06 EA EA200000491A patent/EA002211B1/ru not_active IP Right Cessation
- 1998-11-06 DE DE69814667T patent/DE69814667T2/de not_active Expired - Lifetime
- 1998-11-06 CN CN98810870A patent/CN1114605C/zh not_active Expired - Fee Related
- 1998-11-06 US US09/530,828 patent/US6310210B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69814667T2 (de) | 2004-04-08 |
| ATE240330T1 (de) | 2003-05-15 |
| EA002211B1 (ru) | 2002-02-28 |
| ES2193574T3 (es) | 2003-11-01 |
| AU9761998A (en) | 1999-05-31 |
| EA200000491A1 (ru) | 2000-10-30 |
| BR9813972A (pt) | 2000-09-26 |
| KR100563210B1 (ko) | 2006-03-22 |
| EP1029863A1 (en) | 2000-08-23 |
| PT1029863E (pt) | 2003-09-30 |
| KR20010031595A (ko) | 2001-04-16 |
| CN1278261A (zh) | 2000-12-27 |
| EP1029863B1 (en) | 2003-05-14 |
| CA2309196A1 (en) | 1999-05-20 |
| US6310210B1 (en) | 2001-10-30 |
| CA2309196C (en) | 2007-09-11 |
| JPH11140085A (ja) | 1999-05-25 |
| JP4094710B2 (ja) | 2008-06-04 |
| CN1114605C (zh) | 2003-07-16 |
| AU738823B2 (en) | 2001-09-27 |
| DE69814667D1 (en) | 2003-06-18 |
| WO1999024430A1 (fr) | 1999-05-20 |
| EP1029863A4 (en) | 2001-05-02 |
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