JPH06508820A - 医薬活性剤の局所投与用組成物及び局所投与方法 - Google Patents

医薬活性剤の局所投与用組成物及び局所投与方法

Info

Publication number
JPH06508820A
JPH06508820A JP4507433A JP50743392A JPH06508820A JP H06508820 A JPH06508820 A JP H06508820A JP 4507433 A JP4507433 A JP 4507433A JP 50743392 A JP50743392 A JP 50743392A JP H06508820 A JPH06508820 A JP H06508820A
Authority
JP
Japan
Prior art keywords
salt
composition
weight
glycol
anesthetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4507433A
Other languages
English (en)
Japanese (ja)
Inventor
マンテル　ジュアン　エイ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Noven Pharmaceuticals Inc
Original Assignee
Noven Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27098393&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH06508820(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Noven Pharmaceuticals Inc filed Critical Noven Pharmaceuticals Inc
Publication of JPH06508820A publication Critical patent/JPH06508820A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP4507433A 1991-02-27 1992-02-27 医薬活性剤の局所投与用組成物及び局所投与方法 Pending JPH06508820A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US66182791A 1991-02-27 1991-02-27
US661,827 1991-02-27
US813,196 1991-12-23
US07/813,196 US5234957A (en) 1991-02-27 1991-12-23 Compositions and methods for topical administration of pharmaceutically active agents
PCT/US1992/001730 WO1992015289A1 (en) 1991-02-27 1992-02-27 Compositions and methods for topical administration of pharmaceutically active agents

Publications (1)

Publication Number Publication Date
JPH06508820A true JPH06508820A (ja) 1994-10-06

Family

ID=27098393

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4507433A Pending JPH06508820A (ja) 1991-02-27 1992-02-27 医薬活性剤の局所投与用組成物及び局所投与方法

Country Status (14)

Country Link
US (1) US5234957A (enExample)
EP (2) EP0573576B2 (enExample)
JP (1) JPH06508820A (enExample)
AT (1) ATE144704T1 (enExample)
AU (2) AU658870B2 (enExample)
CA (1) CA2104474C (enExample)
DE (1) DE69214938T3 (enExample)
DK (1) DK0573576T4 (enExample)
ES (1) ES2094906T5 (enExample)
FI (1) FI110161B (enExample)
GR (1) GR3022708T3 (enExample)
NO (1) NO307363B1 (enExample)
SG (2) SG77626A1 (enExample)
WO (1) WO1992015289A1 (enExample)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001517493A (ja) * 1997-09-26 2001-10-09 ノーヴェン ファーマシューティカルズ インコーポレイテッド 生体接着剤組成物及び活性薬剤の局所投与方法
JP2002514589A (ja) * 1998-05-12 2002-05-21 ポリセラピューティックス， インコーポレイテッド 動物組織への生物活性剤の投与のための粘膜付着性組成物
JP2004509222A (ja) * 2000-09-19 2004-03-25 ナショナル　スターチ　アンド　ケミカル　インベストメント　ホールディング　コーポレイション 経皮薬物送達システムにおいて有用な非反応型接着剤
JP2005500292A (ja) * 2001-06-18 2005-01-06 アレックス バタグリア 薬理活性物質を局所適用するための担体としてのゴム樹脂
JP2005511725A (ja) * 2001-12-13 2005-04-28 バイタル ヘルス サイエンシズ プロプライアタリー リミティド 化合物の経皮輸送
JP2006509766A (ja) * 2002-11-26 2006-03-23 エンドー ファーマシューティカルズ， インコーポレイティド 神経障害性知覚喪失処置のための組成物およびその用途
JP2006520801A (ja) * 2003-03-21 2006-09-14 ネックスメド ホールディングス インコーポレイテッド 早漏を治療するための組成物および方法
JP2012529452A (ja) * 2009-06-11 2012-11-22 フォトキュア エイエスエイ 半固体組成物および医薬品
JP2013523893A (ja) * 2010-04-13 2013-06-17 バーブル，ナジブ １−メチル−２’，６’−ピペコロキシリダイドの皮膚医薬組成物および使用方法
JP2017036261A (ja) * 2015-08-11 2017-02-16 株式会社コーセー ミコナゾール硝酸塩含有組成物
JP2021501799A (ja) * 2017-11-01 2021-01-21 クレキシオ バイオサイエンシーズ エルティーディー． 仕上げられた繊維状構造体とその使用および調製の方法

Families Citing this family (191)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5549924A (en) 1987-07-17 1996-08-27 Robin Renee Thill Shlenker Method of forming a membrane, especially a latex or polymer membrane, including a deactivating barrier and indicating layer
US5679399A (en) 1987-07-17 1997-10-21 Bio Barrier, Inc. Method of forming a membrane, especially a latex or polymer membrane, including multiple discrete layers
US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
US5446070A (en) * 1991-02-27 1995-08-29 Nover Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
GB9101986D0 (en) * 1991-01-30 1991-03-13 Smith & Nephew Pharmaceutical compositions
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6024975A (en) * 1992-04-08 2000-02-15 Americare International Diagnostics, Inc. Method of transdermally administering high molecular weight drugs with a polymer skin enhancer
DE4223004A1 (de) * 1992-07-13 1994-01-20 Liedtke Pharmed Gmbh Einzeldosierte halbfeste topische Arzneiform zur Transdermaltherapie
ATE202476T1 (de) * 1992-12-31 2001-07-15 Sunkyong Ind Ltd Pharmazeutische zusammensetzungen mit verbesserter perkutaner absorption für piroxicam
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
GB9305282D0 (en) * 1993-03-15 1993-05-05 Ucb Sa Enantiomers of 1-(4-chlorophenyl)phenylmethyl)-4-(4-methylphenyl)sulphonyl)piperazine
US5578315A (en) * 1993-12-01 1996-11-26 Rutgers, The State University Of New Jersey Mucosal adhesive device for long-acting delivery of pharmaceutical combinations in oral cavity
US5580574A (en) * 1994-04-28 1996-12-03 Hoffmann-La Roche Inc. Pharmaceutical composition for transdermal delivery
US5552153A (en) * 1994-04-28 1996-09-03 Hoffman-La Roche Inc. Pharmaceutical composition for transdermal delivery
KR0121127B1 (ko) * 1994-05-09 1997-11-13 강박광 이온성 고분자 네트웍을 갖는 피부약물전달체계
EP0774954B1 (de) * 1994-07-05 1999-08-04 LTS LOHMANN Therapie-Systeme GmbH Hydrogel für die applikation von therapeutischen und/oder kosmetischen wirkstoffen an die haut
US5585398A (en) * 1994-07-15 1996-12-17 Ernst; Amy A. Topical anesthetic comprising lidocaine, adrenaline, and tetracaine, and its method of use
US6299901B1 (en) 1995-01-13 2001-10-09 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
US6348208B1 (en) 1995-01-13 2002-02-19 Somerset Pharmaceuticals, Inc. Methods and pharmaceutical compositions employing desmethylselegiline
US6033682A (en) 1995-01-13 2000-03-07 Somerset Pharmaceuticals, Inc. S(+) desmethylselegiline and its use in therapeutic methods and pharmaceutical compositions
US6319954B1 (en) 1995-01-13 2001-11-20 Somerset Pharmaceuticals, Inc. S-(+)-desmethylselegiline and its use in the therapeutic methods and pharmaceutical compositions
US5560913A (en) * 1995-01-27 1996-10-01 The Procter & Gamble Company Pharmaceutical compositions
US5567733B1 (en) * 1995-04-27 1999-08-24 Jon G Dishler Irritation relief using nonsteroidal anti-inflammatory compounds
CA2223588C (en) * 1995-06-07 2004-01-06 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
US6316022B1 (en) 1995-06-07 2001-11-13 Noven Pharmaceuticals, Inc. Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
GB9513742D0 (en) * 1995-07-06 1995-09-06 Smith & Nephew Compositions
AU744913B2 (en) * 1995-07-06 2002-03-07 Smith & Nephew Plc Water activable adhesive matrix containing amethocaine
DE19524691A1 (de) * 1995-07-06 1997-01-09 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topischen Therapie von Innenohr und Labyrinth-Symptomen
DE19526031A1 (de) * 1995-07-17 1997-01-23 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topischen Therapie von Rückenschmerz und Muskelverspannung
GB9517062D0 (en) * 1995-08-18 1995-10-25 Scherer Ltd R P Pharmaceutical compositions
DE19546159A1 (de) * 1995-12-11 1997-06-12 Liedtke Pharmed Gmbh Methode und Zusammensetzung einer topisch wirksamen Therapie postoperativer und posttraumatischer Wundschmerzen
US5760102A (en) * 1996-02-20 1998-06-02 Carrington Laboratories, Inc. Uses of denture adhesive containing aloe extract
DE19646392A1 (de) * 1996-11-11 1998-05-14 Lohmann Therapie Syst Lts Zubereitung zur Anwendung in der Mundhöhle mit einer an der Schleimhaut haftklebenden, Pharmazeutika oder Kosmetika zur dosierten Abgabe enthaltenden Schicht
DE19701949A1 (de) * 1997-01-13 1998-07-16 Jenapharm Gmbh Transdermales therapeutisches System
AU6959898A (en) 1997-04-11 1998-11-11 David J. Grainger Compounds and therapies for the prevention of vascular and non-vascular pathol ogies
US6024981A (en) 1997-04-16 2000-02-15 Cima Labs Inc. Rapidly dissolving robust dosage form
US6312450B1 (en) 1997-05-20 2001-11-06 Natural Vision Center, Inc. System and method for improving the appearance of skin
US7150881B2 (en) 1997-06-26 2006-12-19 Mylan Technologies, Inc. Adhesive mixture for transdermal delivery of highly plasticizing drugs
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US20040018241A1 (en) * 1997-09-26 2004-01-29 Noven Pharmaceuticals, Inc. Bioadhesive compositions and methods for topical administration of active agents
US6974590B2 (en) 1998-03-27 2005-12-13 Cima Labs Inc. Sublingual buccal effervescent
US20030091629A1 (en) * 1998-03-27 2003-05-15 Cima Labs Inc. Sublingual buccal effervescent
US6174524B1 (en) 1999-03-26 2001-01-16 Alcon Laboratories, Inc. Gelling ophthalmic compositions containing xanthan gum
US6261547B1 (en) 1998-04-07 2001-07-17 Alcon Manufacturing, Ltd. Gelling ophthalmic compositions containing xanthan gum
WO2000018364A1 (en) 1998-09-25 2000-04-06 Kao Corporation Compositions for oral cavity
US6740341B1 (en) 1998-11-25 2004-05-25 Cima Labs Inc. Taste masking rapid release coating system
EP2260836B1 (en) 1998-11-25 2016-08-10 Cima Labs Inc. Rapid release tablet with coated drug-containing core and surrounding taste masking layer
US6337086B1 (en) 1999-02-06 2002-01-08 Dow Corning Corporation Pressure sensitive adhesive compositions for transdermal drug delivery devices
US7063859B1 (en) 1999-04-28 2006-06-20 Noven Pharmaceuticals, Inc. Barrier film lined backing layer composition and method for topical administration of active agents
US6231957B1 (en) 1999-05-06 2001-05-15 Horst G. Zerbe Rapidly disintegrating flavor wafer for flavor enrichment
US6465004B1 (en) 1999-06-05 2002-10-15 Noven Pharmaceuticals, Inc. Solubility enhancement of drugs in transdermal drug delivery systems and methods of use
US6254594B1 (en) 1999-07-30 2001-07-03 Quadrivium, Llc Disposable light source for photothermal treatment of human tissue
US6264973B1 (en) 1999-08-26 2001-07-24 Fei Enterprises, Ltd. Apparatus and method for anesthetizing the cervical region of a female
US6648872B1 (en) * 1999-09-07 2003-11-18 Stephen M. Zappala Circumferential compression device for intracavernosal anesthesia and method for using same
JP2003513046A (ja) 1999-11-01 2003-04-08 アルコン，インコーポレイテッド フルオロキノロン抗生薬およびキサンタンガムを含有する薬学的組成物
CN1232241C (zh) 2000-03-17 2005-12-21 Lg生活健康株式会社 牙齿增白贴片
US7785572B2 (en) * 2000-03-17 2010-08-31 Lg Household And Health Care Ltd. Method and device for teeth whitening using a dry type adhesive
US6689344B2 (en) 2000-03-17 2004-02-10 Lg Household & Healthcare Ltd. Patches for teeth whitening
US8652446B2 (en) 2000-03-17 2014-02-18 Lg Household & Healthcare Ltd. Apparatus and method for whitening teeth
USRE44145E1 (en) 2000-07-07 2013-04-09 A.V. Topchiev Institute Of Petrochemical Synthesis Preparation of hydrophilic pressure sensitive adhesives having optimized adhesive properties
EP1305033B1 (en) 2000-07-28 2004-10-20 Alcon, Inc Pharmaceutical compositions containing tobramycin and xanthan gum
US6503894B1 (en) 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US20050215727A1 (en) 2001-05-01 2005-09-29 Corium Water-absorbent adhesive compositions and associated methods of manufacture and use
US20050113510A1 (en) 2001-05-01 2005-05-26 Feldstein Mikhail M. Method of preparing polymeric adhesive compositions utilizing the mechanism of interaction between the polymer components
ATE502657T1 (de) 2001-05-01 2011-04-15 Av Topchiev Inst Petrochemical Zweiphasige, wasserabsorbierende bioadhäsive zusammenstezung
US8541021B2 (en) 2001-05-01 2013-09-24 A.V. Topchiev Institute Of Petrochemical Synthesis Hydrogel compositions demonstrating phase separation on contact with aqueous media
EP1390085B1 (en) 2001-05-01 2009-08-05 A.V. Topchiev Institute of Petrochemical Synthesis Hydrogel compositions
US8206738B2 (en) 2001-05-01 2012-06-26 Corium International, Inc. Hydrogel compositions with an erodible backing member
US8840918B2 (en) 2001-05-01 2014-09-23 A. V. Topchiev Institute of Petrochemical Synthesis, Russian Academy of Sciences Hydrogel compositions for tooth whitening
US6613083B2 (en) 2001-05-02 2003-09-02 Eckhard Alt Stent device and method
US20030027833A1 (en) * 2001-05-07 2003-02-06 Cleary Gary W. Compositions and delivery systems for administration of a local anesthetic agent
US20030035839A1 (en) * 2001-05-15 2003-02-20 Peirce Management, Llc Pharmaceutical composition for both intraoral and oral administration
AU2011244985B2 (en) * 2001-06-18 2014-06-12 Jaleva, Llc Gum resin as a carrier for topical application of pharmacologically active agents
US6660292B2 (en) * 2001-06-19 2003-12-09 Hf Flavoring Technology Llp Rapidly disintegrating flavored film for precooked foods
US6946142B2 (en) 2001-06-23 2005-09-20 Lg Household & Healthcare Ltd. Multi-layer patches for teeth whitening
US8900498B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for manufacturing a resulting multi-layer pharmaceutical film
US20070281003A1 (en) * 2001-10-12 2007-12-06 Fuisz Richard C Polymer-Based Films and Drug Delivery Systems Made Therefrom
US7425292B2 (en) 2001-10-12 2008-09-16 Monosol Rx, Llc Thin film with non-self-aggregating uniform heterogeneity and drug delivery systems made therefrom
US20070154527A1 (en) * 2001-10-12 2007-07-05 Monosoirx, Llc Topical film compositions for delivery of actives
US20190328679A1 (en) 2001-10-12 2019-10-31 Aquestive Therapeutics, Inc. Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US20060039958A1 (en) * 2003-05-28 2006-02-23 Monosolrx, Llc. Multi-layer films having uniform content
US8765167B2 (en) * 2001-10-12 2014-07-01 Monosol Rx, Llc Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US20100021526A1 (en) * 2001-10-12 2010-01-28 Monosol Rx, Llc Ph modulated films for delivery of actives
US7666337B2 (en) * 2002-04-11 2010-02-23 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US10285910B2 (en) 2001-10-12 2019-05-14 Aquestive Therapeutics, Inc. Sublingual and buccal film compositions
US8663687B2 (en) 2001-10-12 2014-03-04 Monosol Rx, Llc Film compositions for delivery of actives
US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US7910641B2 (en) * 2001-10-12 2011-03-22 Monosol Rx, Llc PH modulated films for delivery of actives
US11207805B2 (en) 2001-10-12 2021-12-28 Aquestive Therapeutics, Inc. Process for manufacturing a resulting pharmaceutical film
US20030114394A1 (en) * 2001-10-29 2003-06-19 Levine Howard L. Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US8425892B2 (en) * 2001-10-29 2013-04-23 Columbia Laboratories, Inc. Extended, controlled-release pharmaceutical compositions using charged polymers
US20080182841A1 (en) * 2001-10-29 2008-07-31 Levine Howard L Vaginally administered anti-dysrhythmic agents for treating pelvic pain
US8017150B2 (en) * 2002-04-11 2011-09-13 Monosol Rx, Llc Polyethylene oxide-based films and drug delivery systems made therefrom
CA2505796C (en) * 2002-07-22 2012-01-03 Monosolrx Llc Packaging and dispensing of rapid dissolve dosage form
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
CN1826099B (zh) * 2003-07-25 2010-06-09 凡林有限公司 固体剂型药物组合物及其制造方法
US20050074489A1 (en) * 2003-10-01 2005-04-07 Pediamed Pharmaceuticals, Inc. Effervescent and effervescent-dispersion compositions for medicaments and methods of use thereof
US9554984B2 (en) 2003-11-03 2017-01-31 Jaleva Pharmaceuticals, Llc Oral care compositions for topical application
US20050136112A1 (en) * 2003-12-19 2005-06-23 Pediamed Pharmaceuticals, Inc. Oral medicament delivery system
AU2004311879B2 (en) * 2003-12-31 2010-08-05 Phoenix Labs Unlimited Company Effervescent oral opiate dosage form
US7858121B2 (en) * 2003-12-31 2010-12-28 Cima Labs, Inc. Effervescent oral fentanyl dosage form and methods of administering fentanyl
CN102078310B (zh) * 2003-12-31 2013-01-23 奇马实验室公司 大体线性的泡腾口服芬太尼剂型和施用方法
CN102764247B (zh) 2004-01-30 2016-04-20 考里安国际公司 递送活性剂的快速溶解膜
JP5154924B2 (ja) 2004-05-11 2013-02-27 エガレット エイ／エス ジェランガムを含む膨張可能な投与形態
US7666914B2 (en) * 2004-06-03 2010-02-23 Richlin David M Topical preparation and method for transdermal delivery and localization of therapeutic agents
CA2578709C (en) * 2004-06-17 2010-06-15 Virun, Inc. Compositions comprising a mucoadhesive protein and an active principle for mucosal delivery of said agents
US20060004094A1 (en) * 2004-07-02 2006-01-05 Agisim Gary R Composition and method for treating hemorrhoids and/or anorectal disorders
WO2006017807A2 (en) 2004-08-05 2006-02-16 Corium International, Inc. Adhesive composition
WO2006037047A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The r-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
WO2006036936A2 (en) * 2004-09-27 2006-04-06 Bridge Pharma, Inc. The s-isomer of 2-{2-[n-(2-indanyl)-n-phenylamino]ethyl}piperidine and other dermal anesthetic agents
ES2622403T3 (es) * 2004-11-05 2017-07-06 Lead Chemical Co. Ltd. Preparación no acuosa para absorción percutánea que contiene analgésico antiinflamatorio no esteroideo
MX2007008320A (es) * 2005-01-06 2007-09-07 Cima Labs Inc Sistema enmascarador de sabor para farmacos no plastificantes.
US20060278558A1 (en) * 2005-01-14 2006-12-14 Michelle Nivala Non-tearable child resistant blister package
JP5112882B2 (ja) 2005-01-14 2013-01-09 シーマ・ラブス、インコーポレイテッド 曲げてから剥がす錠剤パッケージ
MX2007008586A (es) * 2005-01-14 2007-09-07 Cima Labs Inc Empaque para tabletas resistente a ninos.
DE102005005573B4 (de) * 2005-02-07 2007-03-08 Lts Lohmann Therapie-Systeme Ag Hydrophiles Gelsystem zur Hautpflege auf Basis von Karaya-Gummi
CA2611831C (en) 2005-06-17 2014-09-16 Vital Health Sciences Pty Ltd. A carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US20070048373A1 (en) 2005-08-30 2007-03-01 Cima Labs Inc. Dried milled granulate and methods
US8263047B2 (en) * 2005-09-29 2012-09-11 Wickenhauser Alan J Topical anesthetic for dental procedures
US8623334B1 (en) 2005-09-29 2014-01-07 Alan J. Wickenhauser Topical anesthetic
CA2629810A1 (en) 2005-11-07 2007-05-18 Jaleva, Llc Film-forming resins as a carrier for topical application of pharmacologically active agents
CA2636026A1 (en) * 2006-01-20 2007-07-26 Monosol Rx, Llc Film lined pouch and method of manufacturing this pouch
US20080039405A1 (en) * 2006-04-25 2008-02-14 Croda, Inc. Modification of percutaneous absorption of topically active materials
US20070259307A1 (en) * 2006-05-03 2007-11-08 Discus Dental Impressions, Inc. Instruments having anti-microbial coating
US8637076B2 (en) * 2006-06-01 2014-01-28 Cima Labs Inc. Prednisolone salt formulations
US20070281014A1 (en) * 2006-06-01 2007-12-06 Cima Labs, Inc. Prednisolone salt formulations
US20080069891A1 (en) 2006-09-15 2008-03-20 Cima Labs, Inc. Abuse resistant drug formulation
CA2655809C (en) * 2006-07-21 2013-10-01 Bridge Pharma, Inc. Dermal anesthetic compounds
US20080031944A1 (en) * 2006-08-04 2008-02-07 Cima Labs Inc. Stabilization of lorazepam
CN101516331A (zh) * 2006-09-20 2009-08-26 莫诺索尔克斯有限公司 含有抗泡沫调味剂的可食用水溶性膜
US20080081071A1 (en) * 2006-09-29 2008-04-03 Pradeep Sanghvi Film Embedded Packaging and Method of Making Same
EP2117521B1 (en) 2006-11-03 2012-06-27 Durect Corporation Transdermal delivery systems comprising bupivacaine
US20090214442A1 (en) * 2006-12-01 2009-08-27 Cephalon, Inc. Oral Transmucosal Nicotine Dosage Form
AU2007328373A1 (en) * 2006-12-01 2008-06-12 Cima Labs Inc. Oral transmucosal nicotine dosage form
US20090198262A1 (en) * 2006-12-26 2009-08-06 Discus Dental, Llc Disposable tongue scraper
JP5730572B2 (ja) 2007-09-13 2015-06-10 シマ ラブス インク． 濫用抵抗性製剤
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
WO2010019953A1 (en) 2008-08-15 2010-02-18 Arcion Therapeutics, Inc. High concentration local anesthetic formulations for treating non-neuropathic pain
AU2009298411B2 (en) 2008-10-02 2013-06-06 Mylan Inc. Method of making a multilayer adhesive laminate
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
AU2010204986B2 (en) 2009-01-14 2016-06-02 Corium International, Inc. Transdermal administration of tamsulosin
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
US8475832B2 (en) 2009-08-07 2013-07-02 Rb Pharmaceuticals Limited Sublingual and buccal film compositions
WO2011068722A1 (en) * 2009-12-01 2011-06-09 Noven Pharmaceuticals, Inc. Transdermal testosterone device and delivery
US10610528B2 (en) 2009-12-08 2020-04-07 Intelgenx Corp. Solid oral film dosage forms and methods for making same
US20110136815A1 (en) 2009-12-08 2011-06-09 Horst Zerbe Solid oral film dosage forms and methods for making same
AU2011213557B2 (en) 2010-02-05 2015-05-07 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
EP2552486B1 (en) 2010-03-30 2020-08-12 Phosphagenics Limited Transdermal delivery patch
AU2011252983C1 (en) 2010-05-12 2015-02-19 Unicycive Therapeutics, Inc. Lanthanum carbonate hydroxide, lanthanum oxycarbonate and methods of their manufacture and use
ES2569339T3 (es) 2010-06-10 2016-05-10 Midatech Ltd. Sistemas de administración de película de nanopartículas
US9149959B2 (en) 2010-10-22 2015-10-06 Monosol Rx, Llc Manufacturing of small film strips
US20130304002A1 (en) * 2010-11-09 2013-11-14 Jie Zhang Sheet and liquid combination systems for dermal drug delivery
US9561243B2 (en) 2011-03-15 2017-02-07 Phosphagenics Limited Composition comprising non-neutralised tocol phosphate and a vitamin A compound
ES3034911T3 (en) 2011-05-10 2025-08-26 Itochu Chemical Frontier Corp Non-aqueous patch
US11786455B2 (en) 2011-05-10 2023-10-17 Itochu Chemical Frontier Corporation Non-aqueous patch
WO2012153396A1 (ja) * 2011-05-10 2012-11-15 伊藤忠ケミカルフロンティア株式会社 非水性貼付剤
MX367430B (es) * 2011-09-27 2019-07-11 Itochu Chemical Frontier Corp Parche no acuoso.
US9717697B2 (en) 2012-10-15 2017-08-01 Noven Pharmaceuticals, Inc. Compositions and methods for the transdermal delivery of methylphenidate
JP6359032B2 (ja) 2012-12-28 2018-07-18 ノーヴェン ファーマシューティカルズ インコーポレイテッド 経皮薬物送達用のマルチポリマー組成物
JP2016505006A (ja) 2012-12-28 2016-02-18 ノーヴェン ファーマシューティカルズ インコーポレイテッド レボノルゲストレル及びエチニルエストラジオール用の経皮薬物送達システム
JP2016513537A (ja) 2013-03-14 2016-05-16 セファロン、インク． 経口剤形用の対小児安全カバー
US11337936B2 (en) 2013-03-14 2022-05-24 Noven Pharmaceuticals, Inc. Amphetamine transdermal compositions with acrylic block copolymer
AR095260A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones de anfetaminas transdérmicas estables y métodos de fabricación
AR095259A1 (es) 2013-03-15 2015-09-30 Noven Pharma Composiciones y métodos para la administración transdérmica de fármacos de amina terciaria
US9140513B2 (en) 2013-12-02 2015-09-22 PT Archery Compact compound bow
WO2015137872A1 (en) * 2014-03-13 2015-09-17 Innovator Skåne Ab Tubular or sheet-shaped drug delivery system
EP3253840B1 (en) 2015-02-06 2019-07-31 Noven Pharmaceuticals, INC. Pressure-sensitive adhesives for transdermal drug delivery
US10406116B2 (en) 2015-02-06 2019-09-10 Noven Pharmaceuticals, Inc. Pressure-sensitive adhesives for transdermal drug delivery
USD774154S1 (en) 2015-03-20 2016-12-13 P.T. Archery Llc Archery bow riser
US10973761B2 (en) 2015-12-09 2021-04-13 Phosphagenics Limited Pharmaceutical formulation
US12433850B2 (en) 2016-05-05 2025-10-07 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine and prodrug compositions
US12427121B2 (en) 2016-05-05 2025-09-30 Aquestive Therapeutics, Inc. Enhanced delivery epinephrine compositions
KR20230137362A (ko) 2016-05-05 2023-10-04 어퀘스티브 테라퓨틱스, 아이엔씨. 강화된 전달 에프네프린 조성물
US11273131B2 (en) 2016-05-05 2022-03-15 Aquestive Therapeutics, Inc. Pharmaceutical compositions with enhanced permeation
KR102647670B1 (ko) 2016-12-21 2024-03-15 아베초 바이오테크놀로지 리미티드 방법
US10527382B2 (en) 2017-04-19 2020-01-07 P.T. Archery Llc Non-planar riser plates
US11389844B2 (en) 2018-03-20 2022-07-19 Verde Environmental Technologies, Inc. Blister pack disposal system
GB2575625A (en) 2018-06-22 2020-01-22 Church & Dwight Co Inc Oral care compositions comprising benzocaine and mucoadhesive thin films formed therefrom
AU2019315940B2 (en) 2018-07-31 2025-05-08 Zeltiq Aesthetics, Inc. Methods, devices, and systems for improving skin characteristics
US10695301B2 (en) 2018-09-04 2020-06-30 Babak Ghalili Veterinary cannabinoid and menthol compositions and methods
US10966924B2 (en) 2018-09-04 2021-04-06 Babak Ghalili Veterinary cannabinoid, menthol and anesthetic compositions and methods
US11185526B2 (en) 2018-09-04 2021-11-30 Babak Ghalili Cannabinoid, menthol and caffeine dissolvable film compositions, devices and methods
US11147775B2 (en) 2018-09-04 2021-10-19 Babak Ghalili Cannabinoid and menthol gel compositions, patches and methods
US20200069604A1 (en) * 2018-09-04 2020-03-05 Babak Ghalili Cannabinoid and anesthetic compositions and methods
ES2777899A1 (es) * 2019-02-06 2020-08-06 Hector Alfredo Duilio Polizzi Apósito oral con efecto anestésico
WO2023076281A1 (en) 2021-10-25 2023-05-04 Aquestive Therapeutics, Inc. Oral and nasal compositions and methods of treatment

Family Cites Families (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2142537A (en) * 1936-07-22 1939-01-03 Rare Chemicals Inc Anesthetic ointment
US2277038A (en) * 1937-10-30 1942-03-24 Curtis David Anesthetic preparation
US2352691A (en) * 1941-07-25 1944-07-04 Curtis David Anesthetic compound and preparation
US2501544A (en) * 1946-10-23 1950-03-21 Shellmar Products Corp Therapeutic product
US3249109A (en) * 1963-11-01 1966-05-03 Maeth Harry Topical dressing
DE1617282A1 (de) * 1965-11-30 1975-02-06 Astra Pharma Prod Vorrichtung zur lokalanaesthetisierung durch oertliche aufbringung und verfahren zur herstellung dieser vorrichtung
SE352239B (enExample) * 1966-11-30 1972-12-27 Astra Pharma Prod
US3632740A (en) * 1968-06-13 1972-01-04 Johnson & Johnson Topical device for the therapeutic management of dermatological lesions with steroids
US3640741A (en) * 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
DE2057174A1 (de) * 1970-11-20 1972-05-25 Espe Pharm Praep Pharmazeutisches Produkt,insbesondere injizierbares Lokalanaesthetikum
US3814095A (en) * 1972-03-24 1974-06-04 H Lubens Occlusively applied anesthetic patch
US3972995A (en) * 1975-04-14 1976-08-03 American Home Products Corporation Dosage form
US4675009A (en) * 1977-11-07 1987-06-23 Lec Tec Corporation Drug dispensing device for transdermal delivery of medicaments
SE7713618L (sv) * 1977-12-01 1979-06-02 Astra Laekemedel Ab Lokalanestetisk blandning
SE431092B (sv) * 1979-07-10 1984-01-16 Thuresson Af Ekenstam Bo Terapeutiskt aktiva, substituerade piperidinkarboxianilider
US4307075A (en) * 1979-09-13 1981-12-22 American Home Products Corporation Topical treatment of aphthous stomatitis
CA1208558A (en) * 1982-10-07 1986-07-29 Kazuo Kigasawa Soft buccal
US4608249A (en) * 1982-11-02 1986-08-26 Nitto Electric Industrial Co., Ltd. Hydrophilic therapeutic material
US4466973A (en) * 1983-02-01 1984-08-21 Thomas Rennie Method of treating nasal and sinus congestion
DD217989A1 (de) * 1983-08-09 1985-01-30 Univ Ernst Moritz Arndt Verfahren zur herstellung einer pharmazeutischen zubereitung
EP0139127A1 (en) * 1983-08-22 1985-05-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Transdermal drug delivery device and its preparation
ATE151286T1 (de) * 1983-11-14 1997-04-15 Columbia Lab Inc Bioadhäsive mittel
US4659714A (en) * 1984-03-27 1987-04-21 Dentsply, Ltd. Anesthetic methods for mammals
CA1248450A (en) * 1984-04-05 1989-01-10 Kazuo Kigasawa Soft patch
JPS6160620A (ja) * 1984-09-03 1986-03-28 Teijin Ltd ピログルタミン酸エステル類を含有する医薬品組成物
JPS6164570A (ja) * 1984-09-04 1986-04-02 Akebono Brake Ind Co Ltd アンチスキツド制御方法
US4748022A (en) * 1985-03-25 1988-05-31 Busciglio John A Topical composition
JPS61280423A (ja) * 1985-06-05 1986-12-11 Kiyuukiyuu Yakuhin Kogyo Kk 口腔内粘膜貼付剤
GB8514665D0 (en) * 1985-06-11 1985-07-10 Eroceltique Sa Oral pharmaceutical composition
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
US4713243A (en) * 1986-06-16 1987-12-15 Johnson & Johnson Products, Inc. Bioadhesive extruded film for intra-oral drug delivery and process
JPH0744940B2 (ja) * 1986-12-24 1995-05-17 ライオン株式会社 口腔貼付用基材
DE3714074A1 (de) * 1987-04-28 1988-11-10 Hoechst Ag Grundlage fuer schleimhaut- und prothesenhaft-pasten, verfahren zu ihrer herstellung sowie pasten auf basis dieser grundlage
US4867970A (en) * 1987-05-21 1989-09-19 E. R. Squibb & Sons, Inc. Moistureless oral drug delivery formulation and method for preparing same
DE3726797A1 (de) * 1987-08-12 1989-02-23 Bayer Ag Arzneimittel fuer den bereich der mundhoehle
US4888354A (en) * 1987-12-21 1989-12-19 Theratech, Inc. Skin penetration enhancement using free base and acid addition salt combinations of active agents
EP0331392A3 (en) * 1988-03-01 1990-02-14 Alza Corporation Anesthesia and antisepsis of the skin
US4900552A (en) * 1988-03-30 1990-02-13 Watson Laboratories, Inc. Mucoadhesive buccal dosage forms
GB8810951D0 (en) * 1988-05-09 1988-06-15 Innovata Biomed Ltd Buccal local anaesthetic
US4937078A (en) * 1988-08-26 1990-06-26 Mezei Associates Limited Liposomal local anesthetic and analgesic products
JPH02196717A (ja) * 1988-10-07 1990-08-03 Block Drug Co Inc 歯根膜病の治療方法

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001517493A (ja) * 1997-09-26 2001-10-09 ノーヴェン ファーマシューティカルズ インコーポレイテッド 生体接着剤組成物及び活性薬剤の局所投与方法
JP2002514589A (ja) * 1998-05-12 2002-05-21 ポリセラピューティックス， インコーポレイテッド 動物組織への生物活性剤の投与のための粘膜付着性組成物
JP2004509222A (ja) * 2000-09-19 2004-03-25 ナショナル　スターチ　アンド　ケミカル　インベストメント　ホールディング　コーポレイション 経皮薬物送達システムにおいて有用な非反応型接着剤
US8648082B2 (en) 2001-06-18 2014-02-11 Jaleva, Llc Gum resin as a carrier for topical application of antimicrobial agents
JP2005500292A (ja) * 2001-06-18 2005-01-06 アレックス バタグリア 薬理活性物質を局所適用するための担体としてのゴム樹脂
JP2010155853A (ja) * 2001-06-18 2010-07-15 Alex Battaglia 薬理活性物質を局所適用するための担体としてのゴム樹脂
JP2005511725A (ja) * 2001-12-13 2005-04-28 バイタル ヘルス サイエンシズ プロプライアタリー リミティド 化合物の経皮輸送
JP2006509766A (ja) * 2002-11-26 2006-03-23 エンドー ファーマシューティカルズ， インコーポレイティド 神経障害性知覚喪失処置のための組成物およびその用途
JP2006520801A (ja) * 2003-03-21 2006-09-14 ネックスメド ホールディングス インコーポレイテッド 早漏を治療するための組成物および方法
JP2012529452A (ja) * 2009-06-11 2012-11-22 フォトキュア エイエスエイ 半固体組成物および医薬品
JP2013523893A (ja) * 2010-04-13 2013-06-17 バーブル，ナジブ １−メチル−２’，６’−ピペコロキシリダイドの皮膚医薬組成物および使用方法
JP2017036261A (ja) * 2015-08-11 2017-02-16 株式会社コーセー ミコナゾール硝酸塩含有組成物
JP2021501799A (ja) * 2017-11-01 2021-01-21 クレキシオ バイオサイエンシーズ エルティーディー． 仕上げられた繊維状構造体とその使用および調製の方法

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US5234957A (en) 1993-08-10
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CA2104474A1 (en) 1992-08-28
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