BRPI0418228B8 - forma de dosagem, e, método de preparação de um tablete para administração bucal, gengival ou sublingual de fentanil - Google Patents

forma de dosagem, e, método de preparação de um tablete para administração bucal, gengival ou sublingual de fentanil

Info

Publication number
BRPI0418228B8
BRPI0418228B8 BRPI0418228A BRPI0418228A BRPI0418228B8 BR PI0418228 B8 BRPI0418228 B8 BR PI0418228B8 BR PI0418228 A BRPI0418228 A BR PI0418228A BR PI0418228 A BRPI0418228 A BR PI0418228A BR PI0418228 B8 BRPI0418228 B8 BR PI0418228B8
Authority
BR
Brazil
Prior art keywords
fentanyl
gingival
buccal
tablet
preparing
Prior art date
Application number
BRPI0418228A
Other languages
English (en)
Inventor
Moe Derek
Agarwal Vikas
Habib Walid
Original Assignee
Cima Labs Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34753002&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0418228(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cima Labs Inc filed Critical Cima Labs Inc
Publication of BRPI0418228A publication Critical patent/BRPI0418228A/pt
Publication of BRPI0418228B1 publication Critical patent/BRPI0418228B1/pt
Publication of BRPI0418228B8 publication Critical patent/BRPI0418228B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0007—Effervescent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin

Abstract

"forma de dosagem, e, métodos de tratamento de dor e de episódios de dor incidente de câncer, e de preparação de um tablete para administração bucal, gengival ou sublingual de fentanil". formas de dosagem contendo fentanil e métodos usando as mesmas são descritos. estas formas de dosagem incluem substancialmente menos fentanil em peso do que a formulação oral conhecida e possuem vantagens em termos de custo e de efeitos colaterais. estas formas de dosagem são intencionadas para administração oral de fentanil através da mucosa oral.
BRPI0418228A 2003-12-31 2004-12-30 forma de dosagem, e, método de preparação de um tablete para administração bucal, gengival ou sublingual de fentanil BRPI0418228B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53361903P 2003-12-31 2003-12-31
US61566504P 2004-10-04 2004-10-04
PCT/US2004/043703 WO2005065319A2 (en) 2003-12-31 2004-12-30 Generally linear effervescent oral fentanyl dosage form and methods of administering

Publications (3)

Publication Number Publication Date
BRPI0418228A BRPI0418228A (pt) 2007-04-27
BRPI0418228B1 BRPI0418228B1 (pt) 2017-05-23
BRPI0418228B8 true BRPI0418228B8 (pt) 2021-05-25

Family

ID=34753002

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0418228A BRPI0418228B8 (pt) 2003-12-31 2004-12-30 forma de dosagem, e, método de preparação de um tablete para administração bucal, gengival ou sublingual de fentanil

Country Status (23)

Country Link
US (3) US20050142197A1 (pt)
EP (1) EP1708686B1 (pt)
JP (2) JP2007517054A (pt)
KR (1) KR101184138B1 (pt)
CN (1) CN102078310B (pt)
AT (1) ATE498395T1 (pt)
AU (1) AU2004311880B2 (pt)
BR (1) BRPI0418228B8 (pt)
CA (1) CA2548915C (pt)
CY (1) CY1111458T1 (pt)
DE (1) DE602004031462D1 (pt)
DK (1) DK1708686T3 (pt)
EA (1) EA010826B1 (pt)
HK (1) HK1100480A1 (pt)
HR (1) HRP20110336T1 (pt)
IL (1) IL176449A (pt)
ME (1) ME01300B (pt)
NO (1) NO338714B1 (pt)
NZ (1) NZ548216A (pt)
PL (1) PL1708686T3 (pt)
PT (1) PT1708686E (pt)
RS (1) RS51713B (pt)
WO (1) WO2005065319A2 (pt)

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BRPI0418228B1 (pt) 2017-05-23
JP2013100347A (ja) 2013-05-23
CA2548915A1 (en) 2005-07-21
US8092832B2 (en) 2012-01-10
IL176449A0 (en) 2006-10-05
AU2004311880B2 (en) 2010-08-05
DK1708686T3 (da) 2011-05-16
JP2007517054A (ja) 2007-06-28
EP1708686A4 (en) 2007-12-26
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EP1708686A2 (en) 2006-10-11
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US20110073518A1 (en) 2011-03-31
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US20050142197A1 (en) 2005-06-30
EA010826B1 (ru) 2008-12-30
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CN102078310A (zh) 2011-06-01
WO2005065319A2 (en) 2005-07-21
CA2548915C (en) 2012-10-16
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US7862832B2 (en) 2011-01-04
BRPI0418228A (pt) 2007-04-27
NO338714B1 (no) 2016-10-03
EP1708686B1 (en) 2011-02-16

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