MX2009005671A - Forma de dosificacion de nicotina transmucosal oral. - Google Patents
Forma de dosificacion de nicotina transmucosal oral.Info
- Publication number
- MX2009005671A MX2009005671A MX2009005671A MX2009005671A MX2009005671A MX 2009005671 A MX2009005671 A MX 2009005671A MX 2009005671 A MX2009005671 A MX 2009005671A MX 2009005671 A MX2009005671 A MX 2009005671A MX 2009005671 A MX2009005671 A MX 2009005671A
- Authority
- MX
- Mexico
- Prior art keywords
- dosage form
- nicotine
- oral transmucosal
- nicotine dosage
- transmucosal nicotine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0007—Effervescent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Addiction (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
La invención descrita en la presente es concerniente con una forma de dosificación sólida transmucosal oral útil en el tratamiento de adicción a nicotina o como sustituto o reemplazo de nicotina. En virtud de la formulación en combinación con nicotina, la invención administra transmucosalmente una cantidad efectiva de nicotina al receptor en tanto que permite la realización y manufactura de tal utilizando un tamaño de forma de dosificación relativa pequeña, conveniente y oralmente confortable (por ejemplo, tableta).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87217706P | 2006-12-01 | 2006-12-01 | |
US87212506P | 2006-12-01 | 2006-12-01 | |
PCT/US2007/024218 WO2008069921A2 (en) | 2006-12-01 | 2007-11-20 | Oral transmucosal nicotine dosage form |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009005671A true MX2009005671A (es) | 2009-06-08 |
Family
ID=39365631
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009005671A MX2009005671A (es) | 2006-12-01 | 2007-11-20 | Forma de dosificacion de nicotina transmucosal oral. |
Country Status (9)
Country | Link |
---|---|
US (2) | US20080131508A1 (es) |
EP (1) | EP2101744A2 (es) |
JP (1) | JP2010511611A (es) |
AU (1) | AU2007328373A1 (es) |
BR (1) | BRPI0719428A2 (es) |
CA (1) | CA2670886A1 (es) |
IL (1) | IL198753A0 (es) |
MX (1) | MX2009005671A (es) |
WO (1) | WO2008069921A2 (es) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6974590B2 (en) | 1998-03-27 | 2005-12-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US20030091629A1 (en) * | 1998-03-27 | 2003-05-15 | Cima Labs Inc. | Sublingual buccal effervescent |
EP1578422B1 (en) | 2002-12-20 | 2007-04-11 | NicoNovum AB | A physically and chemically stable nicotine and micorcrystalline cellulose containing particulate material |
US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
US9402809B2 (en) | 2006-03-16 | 2016-08-02 | Niconovum Usa, Inc. | Snuff composition |
US20090214442A1 (en) * | 2006-12-01 | 2009-08-27 | Cephalon, Inc. | Oral Transmucosal Nicotine Dosage Form |
CA2670886A1 (en) * | 2006-12-01 | 2008-06-12 | Cima Labs Inc. | Oral transmucosal nicotine dosage form |
GB2468424B (en) * | 2007-04-02 | 2011-11-09 | Parkinson S Inst | Methods and compositions for reduction of side effects of therapeutic treatments |
EP2197430A2 (en) * | 2007-09-18 | 2010-06-23 | NicoNovum AB | Stable chewing gum compositions comprising maltitol and providing rapid release of nicotine |
US20100018540A1 (en) * | 2008-07-28 | 2010-01-28 | David James Doolittle | Smokeless tobacco products and processes |
WO2010031552A1 (en) * | 2008-09-17 | 2010-03-25 | Niconovum Ab | Process for preparing snuff composition |
US8506936B2 (en) * | 2008-11-25 | 2013-08-13 | Watson Laboratories, Inc. | Stabilized nicotine chewing gum |
EP2213181A1 (en) * | 2009-01-28 | 2010-08-04 | Philip Morris Products S.A. | Smokeless dissolvable compressed tobacco product |
US20110268809A1 (en) * | 2010-04-28 | 2011-11-03 | Paul Andrew Brinkley | Nicotine-Containing Pharmaceutical Compositions |
US9675102B2 (en) | 2010-09-07 | 2017-06-13 | R. J. Reynolds Tobacco Company | Smokeless tobacco product comprising effervescent composition |
EP2729148A4 (en) | 2011-07-06 | 2015-04-22 | Parkinson S Inst | COMPOSITIONS AND METHODS FOR TREATING SYMPTOMS IN PATIENTS WITH PARKINSON'S DISEASE |
US9907748B2 (en) | 2011-10-21 | 2018-03-06 | Niconovum Usa, Inc. | Excipients for nicotine-containing therapeutic compositions |
WO2015051041A1 (en) * | 2013-10-02 | 2015-04-09 | Park Andrew Chunkil | Smoking cessation device |
AU2016211330A1 (en) | 2015-01-28 | 2017-08-03 | Chrono Therapeutics Inc. | Drug delivery methods and systems |
AU2016228779A1 (en) | 2015-03-12 | 2017-09-07 | Chrono Therapeutics Inc. | Craving input and support system |
US11285306B2 (en) | 2017-01-06 | 2022-03-29 | Morningside Venture Investments Limited | Transdermal drug delivery devices and methods |
AU2018378648B2 (en) * | 2017-12-08 | 2021-06-03 | Fertin Pharma A/S | Nicotine tablet |
EP3801732A4 (en) | 2018-05-29 | 2022-04-27 | Morningside Venture Investments Limited | DRUG DELIVERY METHODS AND SYSTEMS |
GB2586301B (en) * | 2020-04-07 | 2021-08-25 | Splash Tm Gmbh | Stable-Foam inhalation Device and Cartridge |
Family Cites Families (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5288498A (en) * | 1985-05-01 | 1994-02-22 | University Of Utah Research Foundation | Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments |
US5855908A (en) * | 1984-05-01 | 1999-01-05 | University Of Utah Research Foundation | Non-dissolvable drug-containing dosage-forms for use in the transmucosal delivery of a drug to a patient |
US4863737A (en) * | 1985-05-01 | 1989-09-05 | University Of Utah | Compositions and methods of manufacture of compressed powder medicaments |
US5288497A (en) * | 1985-05-01 | 1994-02-22 | The University Of Utah | Compositions of oral dissolvable medicaments |
US5783207A (en) * | 1985-05-01 | 1998-07-21 | University Of Utah Research Foundation | Selectively removable nicotine-containing dosage form for use in the transmucosal delivery of nicotine |
US5132114A (en) * | 1985-05-01 | 1992-07-21 | University Of Utah Research Foundation | Compositions and methods of manufacture of compressed powder medicaments |
US5234957A (en) * | 1991-02-27 | 1993-08-10 | Noven Pharmaceuticals, Inc. | Compositions and methods for topical administration of pharmaceutically active agents |
US5079018A (en) * | 1989-08-14 | 1992-01-07 | Neophore Technologies, Inc. | Freeze dry composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs |
US5824334A (en) * | 1989-09-05 | 1998-10-20 | University Of Utah Research Foundation | Tobacco substitute |
US5178878A (en) * | 1989-10-02 | 1993-01-12 | Cima Labs, Inc. | Effervescent dosage form with microparticles |
US5298261A (en) * | 1992-04-20 | 1994-03-29 | Oregon Freeze Dry, Inc. | Rapidly distintegrating tablet |
US5846963A (en) * | 1995-06-07 | 1998-12-08 | University Of Utah Research Foundation | Methods for preventing progressive tissue necrosis, reperfusion injury, bacterial translocation and adult respiratory distress syndrome |
US5503846A (en) * | 1993-03-17 | 1996-04-02 | Cima Labs, Inc. | Base coated acid particles and effervescent formulation incorporating same |
US5549906A (en) * | 1993-07-26 | 1996-08-27 | Pharmacia Ab | Nicotine lozenge and therapeutic method for smoking cessation |
US5382437A (en) * | 1993-10-25 | 1995-01-17 | Hunter Research Corporation | Frozen liquified gas composition and method for oral administration of drugs, biologicals, nutrients and foodstuffs |
US5595761A (en) * | 1994-01-27 | 1997-01-21 | The Board Of Regents Of The University Of Oklahoma | Particulate support matrix for making a rapidly dissolving tablet |
US6165495A (en) * | 1994-04-29 | 2000-12-26 | Blankenship; Mildred | Drug delivery system |
ATE300937T1 (de) * | 1995-05-11 | 2005-08-15 | Univ Utah Res Found | Tabakersatz |
JP4037464B2 (ja) * | 1997-04-01 | 2008-01-23 | シーマ・ラブス・インコーポレイテッド | ブリスタパッケージ及びパッケージタブレット |
US6024981A (en) * | 1997-04-16 | 2000-02-15 | Cima Labs Inc. | Rapidly dissolving robust dosage form |
DE19757059A1 (de) * | 1997-12-20 | 1999-07-01 | Merz & Co Gmbh & Co | Balneologische Brausetablette, Verfahren zu ihrer Herstellung und ihre Verwendung |
US6200604B1 (en) * | 1998-03-27 | 2001-03-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US6974590B2 (en) * | 1998-03-27 | 2005-12-13 | Cima Labs Inc. | Sublingual buccal effervescent |
US20030091629A1 (en) * | 1998-03-27 | 2003-05-15 | Cima Labs Inc. | Sublingual buccal effervescent |
US6358060B2 (en) * | 1998-09-03 | 2002-03-19 | Jsr Llc | Two-stage transmucosal medicine delivery system for symptom relief |
SE9803986D0 (sv) * | 1998-11-23 | 1998-11-23 | Pharmacia & Upjohn Ab | New compositions |
GB9908014D0 (en) * | 1999-04-08 | 1999-06-02 | Scherer Corp R P | Pharmaceutical compositions |
US6162468A (en) * | 1999-08-05 | 2000-12-19 | Med Tech Industries, Inc. | Frozen aqueous solution with nutrients method of packaging and utilizing the same |
US20030180352A1 (en) * | 1999-11-23 | 2003-09-25 | Patel Mahesh V. | Solid carriers for improved delivery of active ingredients in pharmaceutical compositions |
US6961490B2 (en) * | 2000-01-27 | 2005-11-01 | Unaxis-Balzers Aktiengesellschaft | Waveguide plate and process for its production and microtitre plate |
JP2004525928A (ja) * | 2001-03-26 | 2004-08-26 | スミスクライン・ビーチャム・コーポレイション | ニコチン含有経口剤形 |
US20030022910A1 (en) * | 2001-07-05 | 2003-01-30 | R.T. Alamo Ventures I, Inc. | Compositions and methods for sublingual formulations of dihydroergotamine for the treatment of migraine |
US20050034738A1 (en) * | 2003-08-11 | 2005-02-17 | Whalen William F. | Chewing tobacco substitute containing nicotine |
EP1708686B1 (en) * | 2003-12-31 | 2011-02-16 | Cima Labs Inc. | Generally linear effervescent oral fentanyl dosage form and methods of administering |
US7858121B2 (en) * | 2003-12-31 | 2010-12-28 | Cima Labs, Inc. | Effervescent oral fentanyl dosage form and methods of administering fentanyl |
NZ548215A (en) * | 2003-12-31 | 2009-08-28 | Cima Labs Inc | Effervescent oral opiate dosage form |
US20090214442A1 (en) * | 2006-12-01 | 2009-08-27 | Cephalon, Inc. | Oral Transmucosal Nicotine Dosage Form |
CA2670886A1 (en) * | 2006-12-01 | 2008-06-12 | Cima Labs Inc. | Oral transmucosal nicotine dosage form |
-
2007
- 2007-11-20 CA CA002670886A patent/CA2670886A1/en not_active Abandoned
- 2007-11-20 MX MX2009005671A patent/MX2009005671A/es not_active Application Discontinuation
- 2007-11-20 WO PCT/US2007/024218 patent/WO2008069921A2/en active Application Filing
- 2007-11-20 EP EP07867545A patent/EP2101744A2/en not_active Withdrawn
- 2007-11-20 BR BRPI0719428-5A patent/BRPI0719428A2/pt not_active IP Right Cessation
- 2007-11-20 JP JP2009539267A patent/JP2010511611A/ja not_active Withdrawn
- 2007-11-20 AU AU2007328373A patent/AU2007328373A1/en not_active Abandoned
- 2007-11-20 US US11/986,097 patent/US20080131508A1/en not_active Abandoned
-
2009
- 2009-05-14 IL IL198753A patent/IL198753A0/en unknown
-
2011
- 2011-01-11 US US13/004,319 patent/US20110206621A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
JP2010511611A (ja) | 2010-04-15 |
IL198753A0 (en) | 2010-02-17 |
AU2007328373A1 (en) | 2008-06-12 |
US20110206621A1 (en) | 2011-08-25 |
CA2670886A1 (en) | 2008-06-12 |
WO2008069921A3 (en) | 2008-10-30 |
BRPI0719428A2 (pt) | 2014-02-25 |
US20080131508A1 (en) | 2008-06-05 |
WO2008069921A2 (en) | 2008-06-12 |
EP2101744A2 (en) | 2009-09-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HH | Correction or change in general | ||
FA | Abandonment or withdrawal |