JP7082055B2 - 抗癌治療における組み合わせ使用のためのメソテリンキメラ抗原受容体（ｃａｒ）およびｐｄ－ｌ１阻害剤に対する抗体 - Google Patents

抗癌治療における組み合わせ使用のためのメソテリンキメラ抗原受容体（ｃａｒ）およびｐｄ－ｌ１阻害剤に対する抗体 Download PDF

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JP7082055B2
JP7082055B2 JP2018532706A JP2018532706A JP7082055B2 JP 7082055 B2 JP7082055 B2 JP 7082055B2 JP 2018532706 A JP2018532706 A JP 2018532706A JP 2018532706 A JP2018532706 A JP 2018532706A JP 7082055 B2 JP7082055 B2 JP 7082055B2
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ジェニファー・ブログドン
ファイ・ウェン・チャン
ボリス・エンヘルス
ゴードン・ジェイムズ・フリーマン
ゲルハルト・ヨハン・フライ
ジェニファー・マリー・マタラザ
レシュマ・シン
アーリーン・ヘレン・シャープ
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    • A—HUMAN NECESSITIES
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    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A61K40/4254—Adhesion molecules, e.g. NRCAM, EpCAM or cadherins
    • A61K40/4255—Mesothelin [MSLN]
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    • A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K40/00
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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JP2018532706A 2015-12-22 2016-12-21 抗癌治療における組み合わせ使用のためのメソテリンキメラ抗原受容体（ｃａｒ）およびｐｄ－ｌ１阻害剤に対する抗体 Active JP7082055B2 (ja)

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US201562270780P 2015-12-22 2015-12-22
US62/270,780 2015-12-22
PCT/US2016/067957 WO2017112741A1 (en) 2015-12-22 2016-12-21 Mesothelin chimeric antigen receptor (car) and antibody against pd-l1 inhibitor for combined use in anticancer therapy

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JP2022086055A Active JP7524249B2 (ja) 2015-12-22 2022-05-26 抗癌治療における組み合わせ使用のためのメソテリンキメラ抗原受容体（ｃａｒ）およびｐｄ－ｌ１阻害剤に対する抗体

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