JP6742248B2 - 薬物送達装置の使用者を支援するための装置及び方法 - Google Patents
薬物送達装置の使用者を支援するための装置及び方法 Download PDFInfo
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Description
2014年6月3日出願の米国特許仮出願第62/007,007号の優先権利益が主張され、その全内容は参照により本明細書に明示的に組み込まれる。
温度
衝撃または振動暴露
光暴露
(その薬物と関連した)色及び/または濁度
配向
地理的位置
時間的情報
装置が包装から取り出された
装置が冷蔵(例えば、冷蔵庫)から取り出された
装置/薬物温度は、投与の準備が整った
送達を始動させた
装置が患者に適用された
装置が患者上の正しい位置/配向で適用された
カニューレが患者内に挿入された、及び/または正しい組織内に挿入された
送達が進行中である
送達が完了した
エラーが起こった
薬物名もしくは識別、濃度、及び/または量
機密保護情報及び/または偽造防止情報
患者の処方/治療体制
患者の診療現場診断
進捗の自己分析測定
指紋、暗証番号、または他の安全な識別情報
(i)次の特許公開の中に記載されている抗体1A(DSMZ受託番号DSM ACC 2586)、抗体8(DSMZ受託番号DSM ACC 2589)、抗体23(DSMZ受託番号DSM ACC 2588)、及び抗体18を含むがこれらに限定されない、米国特許公開第2006/0040358号(2006年2月23日公開)、同第2005/0008642号(2005年1月13日公開)、同第2004/0228859号(2004年11月18日公開)、
(ii)次の中に記載される抗体2F8、A12、及びIMC−A12を含むがこれらに限定されない、PCT公開第WO06/138729号(2006年12月28日公開)及び同第WO05/016970号(2005年2月24日公開)、及びLu et al.(2004),J.Biol.Chem.279:2856−2865、
(iii)PCT公開第WO07/012614号(2007年2月1日公開)、同第WO07/000328号(2007年1月4日公開)、同第WO06/013472号(2006年2月9日公開)、同第WO05/058967号(2005年6月30日公開)、及び同第WO03/059951号(2003年7月24日公開)、
(iv)次の特許公開の中に記載される抗体7C10、キメラ抗体C7C10、抗体h7C10、抗体7H2M、キメラ抗体*7C10、抗体GM607、ヒト化抗体7C10バージョン1、ヒト化抗体7C10バージョン2、ヒト化抗体7C10バージョン3、及び抗体7H2HMを含むがこれらに限定されない、米国特許公開第2005/0084906号(2005年4月21日公開)、
(v)次の中に記載される抗体EM164、再表面形成されたEM164、ヒト化EM164、huEM164 v1.0、huEM164 v1.1、huEM164 v1.2、及びhuEM164 v1.3を含むがこれらに限定されない、米国特許公開第2005/0249728号(2005年11月10日公開)、同第2005/0186203号(2005年8月25日公開)、同第2004/0265307号(2004年12月30日公開)、及び同第2003/0235582号(2003年12月25日公開)、ならびにMaloney et al.(2003),Cancer Res.63:5073−5083、
(vi)次の中に記載されるATCC受託番号PTA−2792、PTA−2788、PTA−2790、PTA−2791、PTA−2789、PTA−2793、及び抗体2.12.1、2.13.2、2.14.3、3.1.1、4.9.2、及び4.17.3を有するハイブリドーマによって産生された抗体の各々を含むがこれらに限定されない、抗体CP−751,871などの、米国特許第7,037,498号(2006年5月2日発行)、米国特許公開第2005/0244408号(2005年11月30日公開)及び同第2004/0086503号(2004年5月6日公開)、ならびにCohen,et al.(2005),Clinical Cancer Res.11:2063−2073、
(vii)次の特許公開の中に記載される抗体19D12と、ATCCに受託番号PTA−5214で受託されているプラスミド15H12/19D12 HCA(γ4)のポリヌクレオチドによってコードされる重鎖、及びATCCに受託番号PTA−5220で受託されているプラスミド15H12/19D12 LCF(κ)のポリヌクレオチドによってコードされる軽鎖を含む抗体と、を含むがこれらに限定されない、米国特許公開第2005/0136063号(2005年6月23日公開)及び同第2004/0018191号(2004年1月29日公開)、ならびに
(viii)各々及び全てが、特にIGF−1受容体を標的にする前述の抗体、ペプチボディ、及び関連タンパク質等に関して参照によりその全体が本明細書に組み込まれる次の特許公開の中に記載される抗体PINT−6A1、PINT−7A2、PINT−7A4、PINT−7A5、PINT−7A6、PINT−8A1、PINT−9A2、PINT−11A1、PINT−11A2、PINT−11A3、PINT−11A4、PINT−11A5、PINT−11A7、PINT−11A12、PINT−12A1、PINT−12A2、PINT−12A3、PINT−12A4、及びPINT−12A5を含むがこれらに限定されない、米国特許公開第2004/0202655号(2004年10月14日公開)、
Claims (31)
- モバイルコンピューティングデバイス上で実行するアプリケーションを用いて薬物送達装置の使用者を支援するための方法であって、前記モバイルコンピューティングデバイスは、プロセッサ及びメモリを含み、前記方法は、
前記モバイルコンピューティングデバイスの前記プロセッサで、前記薬物送達装置から情報を受信することと、
前記モバイルコンピューティングデバイスの前記プロセッサに、前記モバイルコンピューティングデバイスの前記メモリに保存されている情報に従って、前記薬物送達装置からの前記情報を分析させて、前記薬物送達装置の条件、前記薬物送達装置内に含まれる薬剤の条件、前記薬物送達装置の動作状態、前記薬物送達装置の識別、前記使用者もしくは患者の識別、または前記薬物送達装置内に含まれる薬剤の識別のうちの少なくとも1つを判定させることと、
前記モバイルコンピューティングデバイスの前記プロセッサに、前記薬物送達装置の前記条件、前記薬物送達装置内に含まれる前記薬剤の前記条件、前記薬物送達装置の前記動作状態、前記薬物送達装置の前記識別、前記使用者もしくは患者の前記識別、または前記薬物送達装置内に含まれる前記薬剤の前記識別のうちの前記少なくとも1つの前記判定に基づいて、前記使用者に表示される情報プロンプトまたは指示プロンプトのうちの少なくとも1つを選択させることと、
前記モバイルコンピューティングデバイスの前記プロセッサに、前記アプリケーション内で前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つを含む表示画面を生成させることと、を含む、方法。 - 前記モバイルコンピューティングデバイスの前記プロセッサで前記薬物送達装置から前記情報を受信する前に、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つを前記モバイルコンピューティングデバイスの前記メモリに保存することを含む、請求項1に記載の方法。
- 前記モバイルコンピューティングデバイスの前記プロセッサに、前記薬物送達装置から受信された前記情報を、ネットワークを介して外部コンピューティングデバイスに送信させることを含む、請求項1に記載の方法。
- 前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つの前記選択は、前記外部コンピューティングデバイスに、前記薬物送達装置からの前記情報に基づいて前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つを選択させることを含む、請求項3に記載の方法。
- 前記モバイルコンピューティングデバイスは、スマートフォン、スマートウォッチ、スマート装着可能デバイス、パーソナルコンピュータ、ラップトップコンピュータ、またはタブレットコンピュータのうちの少なくとも1つを含む、請求項1〜4のいずれか一項に記載の方法。
- 前記モバイルコンピューティングデバイスに、前記アプリケーション内で前記表示画面を生成させることは、患者の皮膚上または皮膚に接して前記薬物送達装置を配設するように前記使用者に指示する指示プロンプトを表示することを含む、請求項1〜5のいずれか一項に記載の方法。
- 前記薬物送達装置からの前記情報に基づいて、前記薬物送達装置が許容できる温度または許容できる温度履歴を有するかどうかを判定することを含み、
前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つの選択は、前記薬物送達装置が許容できる温度または許容できる温度履歴を有するという判定に応答して、患者の皮膚上または皮膚に接して前記薬物送達装置を少なくとも配設するように前記使用者に指示する指示プロンプトの選択を含む、請求項1〜6のいずれか一項に記載の方法。 - 前記モバイルコンピューティングデバイスに、前記アプリケーション内で前記表示画面を生成させることは、患者の皮膚に対して前記薬物送達装置を正しく配向するように前記使用者に指示する指示プロンプトを表示することを含む、請求項1〜7のいずれか一項に記載の方法。
- 前記薬物送達装置からの前記情報に基づいて、前記薬物送達装置が患者の皮膚上または皮膚に接して配設されたかどうかを判定することを含み、
前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つの選択は、前記薬物送達装置が前記患者の前記皮膚上にまたは前記皮膚に接して配設されたという判定に応答して、前記患者の前記皮膚に対して前記薬物送達装置を正しく配向するように前記使用者に指示する指示プロンプトの選択を含む、請求項1〜8のいずれか一項に記載の方法。 - 前記モバイルコンピューティングデバイスに、前記アプリケーション内で前記表示画面を生成させることは、前記薬物送達装置を作動させるように前記使用者に指示する指示プロンプトを表示することを含む、請求項1〜9のいずれか一項に記載の方法。
- 前記薬物送達装置からの前記情報に基づいて、患者の皮膚に対する前記薬物送達装置の配向が許容できるかどうかを判定することを含み、
前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つの選択は、前記薬物送達装置の前記配向が許容できるという判定に応答して、前記薬物送達装置を作動させるように前記使用者に指示する指示プロンプトの選択を含む、請求項1〜10のいずれか一項に記載の方法。 - 前記モバイルコンピューティングデバイスに、前記アプリケーション内で前記表示画面を生成させることは、前記薬物送達装置から患者への薬剤の送達の完了を待つように前記使用者に指示する指示プロンプトを表示することを含む、請求項1〜11のいずれか一項に記載の方法。
- 前記薬物送達装置からの前記情報に基づいて、前記薬物送達装置が前記使用者によって作動されたかどうかを判定することを含み、
前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つの選択は、前記薬物送達装置が前記使用者によって作動されたという判定に応答して、前記薬物送達装置から患者への薬剤の送達の完了を待つように前記使用者に指示する指示プロンプトの選択を含む、請求項1〜12のいずれか一項に記載の方法。 - 前記モバイルコンピューティングデバイスに、前記アプリケーション内で前記表示画面を生成させることは、前記薬物送達装置を廃棄するように前記使用者に指示する指示プロンプトを表示することを含む、請求項1〜13のいずれか一項に記載の方法。
- 前記薬物送達装置からの前記情報に基づいて、前記薬物送達装置から患者への薬剤の送達が完了したかどうかを判定することを含み、
前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つの選択は、前記薬物送達装置から前記患者への前記薬剤の送達が完了したという判定に応答して、前記薬物送達装置を廃棄するように前記使用者に指示する指示プロンプトの選択を含む、請求項1〜14のいずれか一項に記載の方法。 - 前記薬物送達装置から前記患者への前記薬剤の送達が完了したという判定に応答して、前記モバイルコンピューティングデバイスの前記プロセッサに、通信ネットワークを介して、薬物送達の前記完了を示すレポートを1つ以上の遠隔コンピューティングデバイスに送信させることを含む、請求項1〜15のいずれか一項に記載の方法。
- モバイルコンピューティングデバイス上で実行するアプリケーションを用いて薬物送達装置の使用者を支援するためのモバイルコンピューティングデバイスであって、
前記薬物送達装置から情報を受信するように構成された通信ユニットと、
プロセッサと、
前記プロセッサに結合されたメモリであって、前記プロセッサによって実行されたとき、前記プロセッサに、
前記薬物送達装置からの前記情報の受信に応答して、前記メモリに保存されている情報に従って、前記薬物送達装置からの前記情報を分析させて、前記薬物送達装置の条件、前記薬物送達装置内に含まれる薬剤の条件、前記薬物送達装置の動作状態、前記薬物送達装置の識別、前記使用者もしくは患者の識別、または前記薬物送達装置内に含まれる薬剤の識別のうちの少なくとも1つを判定させ、
前記薬物送達装置の前記条件、前記薬物送達装置内に含まれる前記薬剤の前記条件、前記薬物送達装置の前記動作状態、前記薬物送達装置の前記識別、前記使用者もしくは前記患者の前記識別、または前記薬物送達装置内に含まれる前記薬剤の前記識別のうちの前記少なくとも1つの前記判定に基づいて、前記使用者に表示される情報プロンプトまたは指示プロンプトのうちの少なくとも1つを選択させ、
前記モバイルコンピューティングデバイス上で実行している前記アプリケーション内で、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つを含む表示画面を生成させる、非一時的なコンピュータ実行可能命令を保存するように構成された、メモリと、を備える、モバイルコンピューティングデバイス。 - 前記通信ユニット、前記プロセッサ、及び前記メモリは、スマートフォン、スマートウォッチ、スマート装着可能デバイス、パーソナルコンピュータ、ラップトップコンピュータ、またはタブレットコンピュータのうちの少なくとも1つに含まれる、請求項17に記載のモバイルコンピューティングデバイス。
- 前記非一時的なコンピュータ実行可能命令は、前記プロセッサによって実行されたとき、前記プロセッサに、
前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて、前記薬物送達装置が許容できる温度または許容できる温度履歴を有するかどうか判定させ、
前記薬物送達装置が許容できる温度または許容できる温度履歴を有するという判定に応答して、患者の皮膚上または皮膚に接して前記薬物送達装置を少なくとも配設するように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させる命令を含む、請求項17または18に記載のモバイルコンピューティングデバイス。 - 前記非一時的なコンピュータ実行可能命令は、前記プロセッサによって実行されたとき、前記プロセッサに、
前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて、前記薬物送達装置が患者の皮膚上または皮膚に接して配設されたかどうかを判定させ、
前記薬物送達装置が前記患者の前記皮膚上にまたは前記皮膚に接して配設されたという判定に応答して、前記患者の前記皮膚に対して前記薬物送達装置を正しく配向するように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させる命令を含む、請求項17〜19のいずれか一項に記載のモバイルコンピューティングデバイス。 - 前記非一時的なコンピュータ実行可能命令は、前記プロセッサによって実行されたとき、前記プロセッサに、
前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて、患者の皮膚に対する前記薬物送達装置の配向が許容できるかどうかを判定させ、
前記薬物送達装置の前記配向が許容できるという決定に応答して、前記薬物送達装置を作動させるように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させる命令を含む、請求項17〜20のいずれか一項に記載のモバイルコンピューティングデバイス。 - 前記非一時的なコンピュータ実行可能命令は、前記プロセッサによって実行されたとき、前記プロセッサに、
前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて、前記薬物送達装置が前記使用者によって作動されたかどうかを判定させ、
前記薬物送達装置が前記使用者によって作動されたという判定に応答して、前記薬物送達装置から患者への薬剤の送達の完了を待つように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させる命令を含む、請求項17〜21のいずれか一項に記載のモバイルコンピューティングデバイス。 - 前記非一時的なコンピュータ実行可能命令は、前記プロセッサによって実行されたとき、前記プロセッサに、
前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて、前記薬物送達装置から患者への薬剤の送達が完了したかどうかを判定させ、
前記薬物送達装置から患者への前記薬剤の送達が完了したという判定に応答して、前記薬物送達装置を廃棄するように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させる命令を含む、請求項17〜22のいずれか一項に記載のモバイルコンピューティングデバイス。 - 前記非一時的なコンピュータ実行可能命令が前記プロセッサによって実行されたとき、前記薬物送達装置から前記患者への前記薬剤の送達が完了したという判定に応答して、前記プロセッサに、通信ネットワークを介して、前記患者への薬物送達の完了を示すレポートを1つ以上の遠隔コンピューティングデバイスに送信するように、前記通信ユニットを制御させる命令を含む、請求項17〜23のいずれか一項に記載のモバイルコンピューティングデバイス。
- 薬物送達装置の使用者を支援するよう動作可能なアプリケーションを提供するためにモバイルコンピューティングデバイスのプロセッサ上で実行される、コンピュータ実行可能命令を有する非一時的なコンピュータ可読記憶媒体であって、前記コンピュータ実行可能命令は、
前記モバイルコンピューティングデバイスで、前記薬物送達装置から情報を受信し、
前記プロセッサに、前記薬物送達装置からの前記情報の受信に応答して、前記非一時的なコンピュータ可読記憶媒体に保存されている情報に従って、前記薬物送達装置からの前記情報を分析させて、前記薬物送達装置の条件、前記薬物送達装置内に含まれる薬剤の条件、前記薬物送達装置の動作状態、前記薬物送達装置の識別、前記使用者もしくは患者の識別、または前記薬物送達装置内に含まれる薬剤の識別のうちの少なくとも1つを判定させ、
前記プロセッサに、前記薬物送達装置の前記条件、前記薬物送達装置内に含まれる前記薬剤の前記条件、前記薬物送達装置の前記動作状態、前記薬物送達装置の前記識別、前記使用者もしくは前記患者の前記識別、または前記薬物送達装置内に含まれる前記薬剤の前記識別のうちの前記少なくとも1つの前記判定に基づいて、前記使用者に表示される情報プロンプトまたは指示プロンプトのうちの少なくとも1つを選択させ、
前記プロセッサに、前記アプリケーション内で前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つを含む、表示画面を生成させるための命令を含む、非一時的なコンピュータ可読記憶媒体。 - 前記コンピュータ実行可能命令は、
前記プロセッサに、前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて前記薬物送達装置が許容できる温度または許容できる温度履歴を有するかどうか判定させ、
前記薬物送達装置が許容できる温度または許容できる温度履歴を有するという判定に応答して、前記プロセッサに、患者の皮膚上または皮膚に接して前記薬物送達装置を少なくとも配設するように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させるための命令を含む、請求項25に記載の非一時的なコンピュータ可読記憶媒体。 - 前記コンピュータ実行可能命令は、
前記プロセッサに、前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて前記薬物送達装置が患者の皮膚上または皮膚に接して配設されたかどうかを判定させ、
前記薬物送達装置が前記患者の前記皮膚上にまたは前記皮膚に接して配設されたという判定に応答して、前記プロセッサに、前記患者の前記皮膚に対して前記薬物送達装置を正しく配向するように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させるための命令を含む、請求項25または26に記載の非一時的なコンピュータ可読記憶媒体。 - 前記コンピュータ実行可能命令は、
前記プロセッサに、前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて患者の皮膚に対する前記薬物送達装置の配向が許容できるかどうかを判定させ、
前記薬物送達装置の前記配向が許容できるという判定に応答して、前記プロセッサに、前記薬物送達装置を作動させるように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させるための命令を含む、請求項25〜27のいずれか一項に記載の非一時的なコンピュータ可読記憶媒体。 - 前記コンピュータ実行可能命令は、
前記プロセッサに、前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて前記薬物送達装置が前記使用者によって作動されたかどうかを判定させ、
前記薬物送達装置が前記使用者によって作動されたという判定に応答して、前記プロセッサに、前記薬物送達装置から患者への薬剤の送達の完了を待つように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させるための命令を含む、請求項25〜28のいずれか一項に記載の非一時的なコンピュータ可読記憶媒体。 - 前記コンピュータ実行可能命令は、
前記プロセッサに、前記薬物送達装置からの前記情報の受信に応答して、前記薬物送達装置からの前記情報に基づいて前記薬物送達装置から患者への薬剤の送達が完了したかどうかを判定させ、
前記薬物送達装置から患者への前記薬剤の送達が完了したという判定に応答して、前記プロセッサに、前記薬物送達装置を廃棄するように前記使用者に指示する、前記情報プロンプトまたは前記指示プロンプトのうちの前記少なくとも1つに対応する指示プロンプトを選択させるための命令を含む、請求項25〜29のいずれか一項に記載の非一時的なコンピュータ可読記憶媒体。 - 前記コンピュータ実行可能命令は、前記薬物送達装置から前記患者への前記薬物の送達が完了したという判定に応答して、前記プロセッサに、通信ネットワークを介して、前記患者への薬物送達の完了を示すレポートを1つ以上の遠隔コンピューティングデバイスに送信させるための命令を含む、請求項25〜30のいずれか一項に記載の非一時的なコンピュータ可読記憶媒体。
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