JP6557147B2 - Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 - Google Patents
Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 Download PDFInfo
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- JP6557147B2 JP6557147B2 JP2015550479A JP2015550479A JP6557147B2 JP 6557147 B2 JP6557147 B2 JP 6557147B2 JP 2015550479 A JP2015550479 A JP 2015550479A JP 2015550479 A JP2015550479 A JP 2015550479A JP 6557147 B2 JP6557147 B2 JP 6557147B2
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- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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- C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
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- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261747672P | 2012-12-31 | 2012-12-31 | |
| US61/747,672 | 2012-12-31 | ||
| PCT/US2013/075959 WO2014105546A1 (en) | 2012-12-31 | 2013-12-18 | Differentiation of human embryonic stem cells into pancreatic endocrine cells using hb9 regulators |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019022275A Division JP6792652B2 (ja) | 2012-12-31 | 2019-02-12 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016503654A JP2016503654A (ja) | 2016-02-08 |
| JP2016503654A5 JP2016503654A5 (https=) | 2017-04-06 |
| JP6557147B2 true JP6557147B2 (ja) | 2019-08-07 |
Family
ID=51017619
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015550479A Active JP6557147B2 (ja) | 2012-12-31 | 2013-12-18 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
| JP2019022275A Active JP6792652B2 (ja) | 2012-12-31 | 2019-02-12 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
| JP2020094794A Active JP7278990B2 (ja) | 2012-12-31 | 2020-05-29 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
| JP2022103271A Withdrawn JP2022130564A (ja) | 2012-12-31 | 2022-06-28 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
| JP2024108633A Pending JP2024129131A (ja) | 2012-12-31 | 2024-07-05 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019022275A Active JP6792652B2 (ja) | 2012-12-31 | 2019-02-12 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
| JP2020094794A Active JP7278990B2 (ja) | 2012-12-31 | 2020-05-29 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
| JP2022103271A Withdrawn JP2022130564A (ja) | 2012-12-31 | 2022-06-28 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
| JP2024108633A Pending JP2024129131A (ja) | 2012-12-31 | 2024-07-05 | Hb9調節物を用いたヒト胚性幹細胞の膵臓内分泌細胞への分化 |
Country Status (17)
| Country | Link |
|---|---|
| US (4) | US10138465B2 (https=) |
| EP (2) | EP4219683A1 (https=) |
| JP (5) | JP6557147B2 (https=) |
| KR (2) | KR101942769B1 (https=) |
| CN (2) | CN111394298A (https=) |
| AR (1) | AR094348A1 (https=) |
| AU (4) | AU2013368224B2 (https=) |
| BR (1) | BR112015015701A2 (https=) |
| CA (1) | CA2896658C (https=) |
| DK (1) | DK2938723T3 (https=) |
| ES (1) | ES2942484T3 (https=) |
| HK (1) | HK1217109A1 (https=) |
| MX (1) | MX2015008578A (https=) |
| PH (1) | PH12015501450A1 (https=) |
| RU (1) | RU2684215C2 (https=) |
| SG (2) | SG11201505112SA (https=) |
| WO (1) | WO2014105546A1 (https=) |
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| US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
| DK2185693T3 (da) | 2007-07-31 | 2019-09-23 | Lifescan Inc | Differentiering af humane embryoniske stamceller |
| CA2954431C (en) | 2007-11-27 | 2021-08-24 | Lifescan, Inc. | Differentiation of human embryonic stem cells to pancreatic cells |
| JP5733986B2 (ja) | 2008-02-21 | 2015-06-10 | ヤンセン バイオテツク,インコーポレーテツド | 細胞の付着、培養、及び剥離のための方法、表面改質されたプレート、並びに組成物 |
| EP2942392B1 (en) | 2008-06-30 | 2018-10-03 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells |
| EP2350265B1 (en) * | 2008-10-31 | 2019-04-17 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells to the pancreatic endocrine lineage |
| KR101774546B1 (ko) | 2008-11-20 | 2017-09-04 | 얀센 바이오테크 인코포레이티드 | 마이크로-캐리어 상의 만능 줄기 세포 배양 |
| KR101687344B1 (ko) | 2008-11-20 | 2016-12-16 | 얀센 바이오테크 인코포레이티드 | 평면 기재상의 세포 부착 및 배양을 위한 방법 및 조성물 |
| CN102482643B (zh) | 2009-07-20 | 2016-06-29 | 詹森生物科技公司 | 人胚胎干细胞的分化 |
| SG10201408552YA (en) | 2009-12-23 | 2015-02-27 | Janssen Biotech Inc | Differentiation of human embryonic stem cells |
| PH12012501686A1 (en) | 2010-03-01 | 2020-10-19 | Janssen Biotech Inc | Methods for purifying cells derived from pluripotent stem cells |
| EP3372672A1 (en) | 2010-08-31 | 2018-09-12 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells |
| FI2794857T3 (fi) | 2011-12-22 | 2026-03-25 | Janssen Biotech Inc | Ihmisen alkion kantasolujen erilaistaminen yksittäisiksi hormonaalisiksi insuliinipositiivisiksi soluiksi |
| EP3450544A1 (en) | 2012-06-08 | 2019-03-06 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into pancreatic endodrine cells |
| ES2837763T3 (es) | 2012-12-31 | 2021-07-01 | Janssen Biotech Inc | Cultivo de células madre embrionarias humanas en la interconexión aire-líquido para la diferenciación en células endocrinas pancreáticas |
| BR112015015714A2 (pt) | 2012-12-31 | 2017-07-11 | Janssen Biotech Inc | suspensão e aglomeração de células pluripotentes humanas para diferenciação em célu-las endócrinas pancreáticas |
| US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
| DK2938723T3 (da) | 2012-12-31 | 2023-02-20 | Janssen Biotech Inc | Differentiering af humane embryonale stamceller til pancreatiske endokrine celler under anvendelse af hb9-regulatorer |
| CN120796168A (zh) | 2013-06-11 | 2025-10-17 | 哈佛学院校长同事会 | SC-β细胞以及用于产生其的组合物和方法 |
| WO2015175307A1 (en) | 2014-05-16 | 2015-11-19 | Janssen Biotech, Inc. | Use of small molecules to enhance mafa expression in pancreatic endocrine cells |
| EP3191583A1 (en) * | 2014-09-08 | 2017-07-19 | Fundación Pública Andaluza Progreso Y Salud | Method for obtaining pancreatic beta cell surrogates by increasing pancreatic and duodenal homeobox 1 (pdx-1) expression |
| US9371516B2 (en) | 2014-09-19 | 2016-06-21 | Regenerative Medical Solutions, Inc. | Compositions and methods for differentiating stem cells into cell populations comprising beta-like cells |
| CN107614678B (zh) | 2014-12-18 | 2021-04-30 | 哈佛学院校长同事会 | 干细胞来源的β细胞的产生方法及其使用方法 |
| WO2016100898A1 (en) | 2014-12-18 | 2016-06-23 | President And Fellows Of Harvard College | Serum-free in vitro directed differentiation protocol for generating stem cell-derived b cells and uses thereof |
| EP3234110B1 (en) * | 2014-12-18 | 2024-02-28 | President and Fellows of Harvard College | METHODS FOR GENERATING STEM CELL-DERIVED ß CELLS AND USES THEREOF |
| EP3234109A4 (en) * | 2014-12-19 | 2018-06-27 | Janssen Biotech, Inc. | Suspension culturing of pluripotent stem cells |
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| EP3328404A4 (en) * | 2015-07-27 | 2018-12-26 | The Regents of The University of California | Methods and compositions for producing pancreatic beta cells |
| CN108699515A (zh) | 2016-02-24 | 2018-10-23 | 诺和诺德股份有限公司 | 由人多能干细胞衍生的内分泌祖细胞生成功能性β细胞 |
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| MD4194548T2 (ro) | 2016-06-21 | 2026-02-28 | Janssen Biotech Inc | Generarea de celule beta funcționale derivate din celule stem pluripotente umane care posedă respirație mitocondrială dependentă - de glucoză și răspuns la secreția de insulină în două faze |
| CA3042495A1 (en) | 2016-11-10 | 2018-05-17 | Viacyte, Inc. | Pdx1 pancreatic endoderm cells in cell delivery devices and methods thereof |
| US10391156B2 (en) | 2017-07-12 | 2019-08-27 | Viacyte, Inc. | University donor cells and related methods |
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| US12378572B2 (en) | 2018-09-07 | 2025-08-05 | Crispr Therapeutics Ag | Universal donor cells |
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