JP6535602B2 - 免疫療法のための組成物および方法 - Google Patents
免疫療法のための組成物および方法 Download PDFInfo
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- JP6535602B2 JP6535602B2 JP2015559298A JP2015559298A JP6535602B2 JP 6535602 B2 JP6535602 B2 JP 6535602B2 JP 2015559298 A JP2015559298 A JP 2015559298A JP 2015559298 A JP2015559298 A JP 2015559298A JP 6535602 B2 JP6535602 B2 JP 6535602B2
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C—CHEMISTRY; METALLURGY
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- C—CHEMISTRY; METALLURGY
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
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- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
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- Hematology (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
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- Oncology (AREA)
- Microbiology (AREA)
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- Communicable Diseases (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361769543P | 2013-02-26 | 2013-02-26 | |
| US61/769,543 | 2013-02-26 | ||
| PCT/US2014/018667 WO2014134165A1 (en) | 2013-02-26 | 2014-02-26 | Compositions and methods for immunotherapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018135716A Division JP2018157836A (ja) | 2013-02-26 | 2018-07-19 | 免疫療法のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016508728A JP2016508728A (ja) | 2016-03-24 |
| JP2016508728A5 JP2016508728A5 (enExample) | 2017-03-30 |
| JP6535602B2 true JP6535602B2 (ja) | 2019-06-26 |
Family
ID=51428766
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015559298A Active JP6535602B2 (ja) | 2013-02-26 | 2014-02-26 | 免疫療法のための組成物および方法 |
| JP2018135716A Withdrawn JP2018157836A (ja) | 2013-02-26 | 2018-07-19 | 免疫療法のための組成物および方法 |
| JP2020000218A Withdrawn JP2020054387A (ja) | 2013-02-26 | 2020-01-06 | 免疫療法のための組成物および方法 |
| JP2022041468A Active JP7367104B2 (ja) | 2013-02-26 | 2022-03-16 | 免疫療法のための組成物および方法 |
| JP2023097618A Withdrawn JP2023107931A (ja) | 2013-02-26 | 2023-06-14 | 免疫療法のための組成物および方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018135716A Withdrawn JP2018157836A (ja) | 2013-02-26 | 2018-07-19 | 免疫療法のための組成物および方法 |
| JP2020000218A Withdrawn JP2020054387A (ja) | 2013-02-26 | 2020-01-06 | 免疫療法のための組成物および方法 |
| JP2022041468A Active JP7367104B2 (ja) | 2013-02-26 | 2022-03-16 | 免疫療法のための組成物および方法 |
| JP2023097618A Withdrawn JP2023107931A (ja) | 2013-02-26 | 2023-06-14 | 免疫療法のための組成物および方法 |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US10124023B2 (enExample) |
| EP (2) | EP2961831B1 (enExample) |
| JP (5) | JP6535602B2 (enExample) |
| KR (5) | KR20200113284A (enExample) |
| CN (3) | CN113699114A (enExample) |
| AU (3) | AU2014223601B9 (enExample) |
| BR (1) | BR112015020516A2 (enExample) |
| CA (1) | CA2902370C (enExample) |
| CY (1) | CY1123326T1 (enExample) |
| DK (1) | DK2961831T3 (enExample) |
| ES (1) | ES2823586T3 (enExample) |
| HR (1) | HRP20201419T1 (enExample) |
| HU (1) | HUE050787T2 (enExample) |
| IL (4) | IL298125A (enExample) |
| LT (1) | LT2961831T (enExample) |
| MX (2) | MX378463B (enExample) |
| MY (1) | MY175869A (enExample) |
| PH (1) | PH12015501880A1 (enExample) |
| PL (1) | PL2961831T3 (enExample) |
| PT (1) | PT2961831T (enExample) |
| RS (1) | RS60759B1 (enExample) |
| RU (1) | RU2680010C2 (enExample) |
| SA (2) | SA517381708B1 (enExample) |
| SG (2) | SG10202001030VA (enExample) |
| SI (1) | SI2961831T1 (enExample) |
| SM (1) | SMT202000536T1 (enExample) |
| WO (1) | WO2014134165A1 (enExample) |
| ZA (2) | ZA201506511B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022069603A (ja) * | 2013-02-26 | 2022-05-11 | メモリアル スローン ケタリング キャンサー センター | 免疫療法のための組成物および方法 |
Families Citing this family (254)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014117121A1 (en) | 2013-01-28 | 2014-07-31 | St. Jude Children's Research Hospital, Inc. | A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease |
| AU2014386824B2 (en) * | 2013-03-15 | 2019-05-09 | Memorial Sloan-Kettering Cancer Center | Compositions and methods for immunotherapy |
| MY171854A (en) | 2013-03-29 | 2019-11-05 | Sumitomo Dainippon Pharma Co Ltd | Wt1 antigen peptide conjugate vaccine |
| WO2015077717A1 (en) | 2013-11-25 | 2015-05-28 | The Broad Institute Inc. | Compositions and methods for diagnosing, evaluating and treating cancer by means of the dna methylation status |
| US11725237B2 (en) | 2013-12-05 | 2023-08-15 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| EP3082853A2 (en) | 2013-12-20 | 2016-10-26 | The Broad Institute, Inc. | Combination therapy with neoantigen vaccine |
| US11390921B2 (en) | 2014-04-01 | 2022-07-19 | Adaptive Biotechnologies Corporation | Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs) |
| EP4219687B1 (en) | 2014-04-23 | 2024-08-14 | Juno Therapeutics, Inc. | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| CA2948462A1 (en) | 2014-05-15 | 2015-11-19 | National University Of Singapore | Modified natural killer cells and uses thereof |
| BR112017001183A2 (pt) | 2014-07-21 | 2017-11-28 | Novartis Ag | tratamento de câncer usando receptor de antígeno quimérico anti-bcma humanizado |
| CN107109419B (zh) | 2014-07-21 | 2020-12-22 | 诺华股份有限公司 | 使用cd33嵌合抗原受体治疗癌症 |
| HRP20201153T1 (hr) | 2014-08-08 | 2021-01-22 | The Board Of Trustees Of The Leland Stanford Junior University | Pd-1 sredstva visokog afiniteta i načini uporabe |
| TWI751102B (zh) | 2014-08-28 | 2022-01-01 | 美商奇諾治療有限公司 | 對cd19具專一性之抗體及嵌合抗原受體 |
| EA201790624A1 (ru) * | 2014-09-17 | 2017-08-31 | Новартис Аг | Нацеливание цитотоксических клеток с химерными рецепторами для адоптивной иммунотерапии |
| EP3209690B1 (en) | 2014-10-20 | 2021-05-05 | Juno Therapeutics, Inc. | Methods and compositions for dosing in adoptive cell therapy |
| JP7005346B2 (ja) * | 2014-10-27 | 2022-02-04 | フレッド ハッチンソン キャンサー リサーチ センター | 養子細胞免疫療法の有効性を増強させるための組成物および方法 |
| EP3212225B1 (en) * | 2014-10-31 | 2025-11-19 | The Trustees of the University of Pennsylvania | Methods and compositions for modified t cells |
| CN113429485A (zh) | 2014-12-05 | 2021-09-24 | 纪念斯隆-凯特琳癌症中心 | 靶向b-细胞成熟抗原的抗体及其用途 |
| JP7174522B2 (ja) | 2014-12-05 | 2022-11-17 | メモリアル スローン ケタリング キャンサー センター | Fc受容体様5を標的とするキメラ抗原受容体およびその使用 |
| MX2017007244A (es) | 2014-12-05 | 2018-01-25 | Memorial Sloan Kettering Cancer Center | Receptores de antigeno quimerico que se dirigen al antigeno de maduracion de celulas b y sus usos. |
| US10975442B2 (en) | 2014-12-19 | 2021-04-13 | Massachusetts Institute Of Technology | Molecular biomarkers for cancer immunotherapy |
| EP3234130B1 (en) | 2014-12-19 | 2020-11-25 | The Broad Institute, Inc. | Methods for profiling the t-cell- receptor repertoire |
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