JP6535602B2 - 免疫療法のための組成物および方法 - Google Patents
免疫療法のための組成物および方法 Download PDFInfo
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- JP6535602B2 JP6535602B2 JP2015559298A JP2015559298A JP6535602B2 JP 6535602 B2 JP6535602 B2 JP 6535602B2 JP 2015559298 A JP2015559298 A JP 2015559298A JP 2015559298 A JP2015559298 A JP 2015559298A JP 6535602 B2 JP6535602 B2 JP 6535602B2
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- A61K40/4274—Prostate associated antigens e.g. Prostate stem cell antigen [PSCA]; Prostate carcinoma tumor antigen [PCTA]; Prostatic acid phosphatase [PAP]; Prostate-specific G-protein-coupled receptor [PSGR]
- A61K40/4276—Prostate specific membrane antigen [PSMA]
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
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- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
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- Molecular Biology (AREA)
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- Wood Science & Technology (AREA)
- Hematology (AREA)
- Reproductive Health (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
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- Transplantation (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361769543P | 2013-02-26 | 2013-02-26 | |
| US61/769,543 | 2013-02-26 | ||
| PCT/US2014/018667 WO2014134165A1 (en) | 2013-02-26 | 2014-02-26 | Compositions and methods for immunotherapy |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018135716A Division JP2018157836A (ja) | 2013-02-26 | 2018-07-19 | 免疫療法のための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016508728A JP2016508728A (ja) | 2016-03-24 |
| JP2016508728A5 JP2016508728A5 (enExample) | 2017-03-30 |
| JP6535602B2 true JP6535602B2 (ja) | 2019-06-26 |
Family
ID=51428766
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015559298A Expired - Fee Related JP6535602B2 (ja) | 2013-02-26 | 2014-02-26 | 免疫療法のための組成物および方法 |
| JP2018135716A Withdrawn JP2018157836A (ja) | 2013-02-26 | 2018-07-19 | 免疫療法のための組成物および方法 |
| JP2020000218A Withdrawn JP2020054387A (ja) | 2013-02-26 | 2020-01-06 | 免疫療法のための組成物および方法 |
| JP2022041468A Active JP7367104B2 (ja) | 2013-02-26 | 2022-03-16 | 免疫療法のための組成物および方法 |
| JP2023097618A Withdrawn JP2023107931A (ja) | 2013-02-26 | 2023-06-14 | 免疫療法のための組成物および方法 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018135716A Withdrawn JP2018157836A (ja) | 2013-02-26 | 2018-07-19 | 免疫療法のための組成物および方法 |
| JP2020000218A Withdrawn JP2020054387A (ja) | 2013-02-26 | 2020-01-06 | 免疫療法のための組成物および方法 |
| JP2022041468A Active JP7367104B2 (ja) | 2013-02-26 | 2022-03-16 | 免疫療法のための組成物および方法 |
| JP2023097618A Withdrawn JP2023107931A (ja) | 2013-02-26 | 2023-06-14 | 免疫療法のための組成物および方法 |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US10124023B2 (enExample) |
| EP (2) | EP2961831B1 (enExample) |
| JP (5) | JP6535602B2 (enExample) |
| KR (5) | KR102593475B1 (enExample) |
| CN (3) | CN113684185A (enExample) |
| AU (3) | AU2014223601B9 (enExample) |
| BR (1) | BR112015020516A2 (enExample) |
| CA (1) | CA2902370C (enExample) |
| CY (1) | CY1123326T1 (enExample) |
| DK (1) | DK2961831T3 (enExample) |
| ES (1) | ES2823586T3 (enExample) |
| HR (1) | HRP20201419T1 (enExample) |
| HU (1) | HUE050787T2 (enExample) |
| IL (4) | IL298125A (enExample) |
| LT (1) | LT2961831T (enExample) |
| MX (2) | MX378463B (enExample) |
| MY (1) | MY175869A (enExample) |
| PH (1) | PH12015501880A1 (enExample) |
| PL (1) | PL2961831T3 (enExample) |
| PT (1) | PT2961831T (enExample) |
| RS (1) | RS60759B1 (enExample) |
| RU (1) | RU2680010C2 (enExample) |
| SA (2) | SA515360944B1 (enExample) |
| SG (2) | SG11201506964SA (enExample) |
| SI (1) | SI2961831T1 (enExample) |
| SM (1) | SMT202000536T1 (enExample) |
| WO (1) | WO2014134165A1 (enExample) |
| ZA (2) | ZA201506511B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022069603A (ja) * | 2013-02-26 | 2022-05-11 | メモリアル スローン ケタリング キャンサー センター | 免疫療法のための組成物および方法 |
Families Citing this family (258)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014117121A1 (en) | 2013-01-28 | 2014-07-31 | St. Jude Children's Research Hospital, Inc. | A chimeric receptor with nkg2d specificity for use in cell therapy against cancer and infectious disease |
| SG11201507688VA (en) * | 2013-03-15 | 2015-10-29 | Sloan Kettering Inst Cancer | Compositions and methods for immunotherapy |
| DK2982681T3 (en) | 2013-03-29 | 2018-12-10 | Sumitomo Dainippon Pharma Co Ltd | WT1 ANTIGENPEPTIDKONJUGATVACCINE |
| US10801070B2 (en) | 2013-11-25 | 2020-10-13 | The Broad Institute, Inc. | Compositions and methods for diagnosing, evaluating and treating cancer |
| US11725237B2 (en) | 2013-12-05 | 2023-08-15 | The Broad Institute Inc. | Polymorphic gene typing and somatic change detection using sequencing data |
| JP7060324B2 (ja) | 2013-12-20 | 2022-04-26 | ザ・ブロード・インスティテュート・インコーポレイテッド | ネオ抗原ワクチンによる併用療法 |
| US11390921B2 (en) | 2014-04-01 | 2022-07-19 | Adaptive Biotechnologies Corporation | Determining WT-1 specific T cells and WT-1 specific T cell receptors (TCRs) |
| ES2995052T3 (en) | 2014-04-23 | 2025-02-05 | Juno Therapeutics Inc | Methods for isolating, culturing, and genetically engineering immune cell populations for adoptive therapy |
| KR20210014210A (ko) | 2014-05-15 | 2021-02-08 | 내셔널 유니버시티 오브 싱가포르 | 변형된 천연 살해 세포 및 그의 용도 |
| US10174095B2 (en) | 2014-07-21 | 2019-01-08 | Novartis Ag | Nucleic acid encoding a humanized anti-BCMA chimeric antigen receptor |
| SG10201913765YA (en) | 2014-07-21 | 2020-03-30 | Novartis Ag | Treatment of cancer using a cd33 chimeric antigen receptor |
| HRP20201153T1 (hr) | 2014-08-08 | 2021-01-22 | The Board Of Trustees Of The Leland Stanford Junior University | Pd-1 sredstva visokog afiniteta i načini uporabe |
| TWI805109B (zh) | 2014-08-28 | 2023-06-11 | 美商奇諾治療有限公司 | 對cd19具專一性之抗體及嵌合抗原受體 |
| JP6839074B2 (ja) * | 2014-09-17 | 2021-03-03 | ノバルティス アーゲー | 養子免疫療法のためのキメラ受容体での細胞毒性細胞のターゲティング |
| EP3209690B1 (en) | 2014-10-20 | 2021-05-05 | Juno Therapeutics, Inc. | Methods and compositions for dosing in adoptive cell therapy |
| KR102357004B1 (ko) * | 2014-10-27 | 2022-01-27 | 프레드 헛친슨 켄서 리서치 센터 | 입양 세포 면역요법의 효능을 강화하기 위한 조성물 및 방법 |
| HK1243333A1 (zh) * | 2014-10-31 | 2018-07-13 | The Trustees Of The University Of Pennsylvania | 用於修饰的t细胞的方法和组合物 |
| EP4310097A3 (en) | 2014-12-05 | 2024-04-03 | Memorial Sloan Kettering Cancer Center | Chimeric antigen receptors targeting b-cell maturation antigen and uses thereof |
| SG11201704550XA (en) | 2014-12-05 | 2017-07-28 | Memorial Sloan Kettering Cancer Center | Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof |
| CA2969877A1 (en) | 2014-12-05 | 2016-06-09 | Memorial Sloan-Kettering Cancer Center | Antibodies targeting b-cell maturation antigen and methods of use |
| WO2016100975A1 (en) | 2014-12-19 | 2016-06-23 | Massachsetts Institute Ot Technology | Molecular biomarkers for cancer immunotherapy |
| EP4636401A2 (en) | 2014-12-19 | 2025-10-22 | The Broad Institute, Inc. | Methods for profiling the t-cell-receptor repertoire |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2022069603A (ja) * | 2013-02-26 | 2022-05-11 | メモリアル スローン ケタリング キャンサー センター | 免疫療法のための組成物および方法 |
| JP7367104B2 (ja) | 2013-02-26 | 2023-10-23 | メモリアル スローン-ケタリング キャンサー センター | 免疫療法のための組成物および方法 |
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