JP6132850B2 - グリタゾンおよびｎｒｆ２アクチベーターを含む医薬組成物 - Google Patents

グリタゾンおよびｎｒｆ２アクチベーターを含む医薬組成物 Download PDF

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JP6132850B2
JP6132850B2 JP2014547838A JP2014547838A JP6132850B2 JP 6132850 B2 JP6132850 B2 JP 6132850B2 JP 2014547838 A JP2014547838 A JP 2014547838A JP 2014547838 A JP2014547838 A JP 2014547838A JP 6132850 B2 JP6132850 B2 JP 6132850B2
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fumarate
ppar gamma
pioglitazone
nrf2
treatment
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JP2015504871A (ja
JP2015504871A5 (enExample
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コリン カース，ビョルン
コリン カース，ビョルン
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
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    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
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    • A61K31/26—Cyanate or isocyanate esters; Thiocyanate or isothiocyanate esters
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Psychiatry (AREA)
  • Transplantation (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2014547838A 2011-12-19 2012-12-10 グリタゾンおよびｎｒｆ２アクチベーターを含む医薬組成物 Expired - Fee Related JP6132850B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
EP11194292 2011-12-19
EP11194292.6 2011-12-19
EP12004652.9 2012-06-21
EP12004652 2012-06-21
US201261663761P 2012-06-25 2012-06-25
US61/663,761 2012-06-25
US13/654,632 2012-10-18
US13/654,632 US20130158077A1 (en) 2011-12-19 2012-10-18 Pharmaceutical compositions
PCT/EP2012/074915 WO2013092269A1 (en) 2011-12-19 2012-12-10 Pharmaceutical compositions comprising glitazones and nrf2 activators

Publications (3)

Publication Number Publication Date
JP2015504871A JP2015504871A (ja) 2015-02-16
JP2015504871A5 JP2015504871A5 (enExample) 2017-04-13
JP6132850B2 true JP6132850B2 (ja) 2017-05-24

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JP2014547838A Expired - Fee Related JP6132850B2 (ja) 2011-12-19 2012-12-10 グリタゾンおよびｎｒｆ２アクチベーターを含む医薬組成物

Country Status (18)

Country Link
US (6) US20130158077A1 (enExample)
EP (1) EP2793876B1 (enExample)
JP (1) JP6132850B2 (enExample)
KR (2) KR20220139414A (enExample)
CN (1) CN103998035B (enExample)
AR (1) AR089301A1 (enExample)
AU (4) AU2012358420B9 (enExample)
BR (1) BR112014014809A8 (enExample)
CA (1) CA2859635C (enExample)
CL (1) CL2014001639A1 (enExample)
EA (1) EA201400729A1 (enExample)
ES (1) ES2959111T3 (enExample)
HK (1) HK1200711A1 (enExample)
IL (1) IL233134A0 (enExample)
MX (2) MX394473B (enExample)
PH (1) PH12014501029A1 (enExample)
SG (1) SG11201403241XA (enExample)
WO (1) WO2013092269A1 (enExample)

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