JP5599322B2 - エクスビボ肺ケアのためのシステムおよび方法 - Google Patents

エクスビボ肺ケアのためのシステムおよび方法 Download PDF

Info

Publication number
JP5599322B2
JP5599322B2 JP2010545201A JP2010545201A JP5599322B2 JP 5599322 B2 JP5599322 B2 JP 5599322B2 JP 2010545201 A JP2010545201 A JP 2010545201A JP 2010545201 A JP2010545201 A JP 2010545201A JP 5599322 B2 JP5599322 B2 JP 5599322B2
Authority
JP
Japan
Prior art keywords
lung
gas
perfusion fluid
lungs
perfusion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2010545201A
Other languages
English (en)
Japanese (ja)
Other versions
JP2011511000A5 (enExample
JP2011511000A (ja
Inventor
ロバート フィシュマン
ロバート ヘイベナー
イハブ アブデル ファタ
アナス アブデルアジム
スコット ニューウェル
トム ビショップ
タマー ハイヤル
スタンレー チー
ロナルド テイラー
ダグ ハリオット
レメール マシュー デ
ポール マレー
ジョン サリバン
マーク アンダーソン
リチャード ブリンガム
ドリエル マイケル ヴァン
ワリード ハッサネイン
Original Assignee
トランスメディックス インコーポレイティッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by トランスメディックス インコーポレイティッド filed Critical トランスメディックス インコーポレイティッド
Publication of JP2011511000A publication Critical patent/JP2011511000A/ja
Publication of JP2011511000A5 publication Critical patent/JP2011511000A5/ja
Application granted granted Critical
Publication of JP5599322B2 publication Critical patent/JP5599322B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/14Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142Apparatus
    • A01N1/143Apparatus for organ perfusion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2010545201A 2008-01-31 2009-01-30 エクスビボ肺ケアのためのシステムおよび方法 Active JP5599322B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US2497608P 2008-01-31 2008-01-31
US61/024976 2008-01-31
US12/099687 2008-04-08
US12/099,715 US9247728B2 (en) 2008-01-31 2008-04-08 Systems and methods for ex vivo lung care
US12/099717 2008-04-08
US12/099,728 US9814230B2 (en) 2008-01-31 2008-04-08 Systems and methods for ex vivo lung care
US12/099,717 US8420380B2 (en) 2008-01-31 2008-04-08 Systems and methods for ex vivo lung care
US12/099,725 US9462802B2 (en) 2008-01-31 2008-04-08 Systems and methods for ex vivo lung care
US12/099,687 US10750738B2 (en) 2008-01-31 2008-04-08 Systems and methods for ex vivo lung care
US12/099725 2008-04-08
US12/099728 2008-04-08
US12/099715 2008-04-08
PCT/US2009/032619 WO2009099939A2 (en) 2008-01-31 2009-01-30 Systems and methods for ex vivo lung care

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2014164178A Division JP6144238B2 (ja) 2008-01-31 2014-08-12 エクスビボ肺ケアのためのシステムおよび方法

Publications (3)

Publication Number Publication Date
JP2011511000A JP2011511000A (ja) 2011-04-07
JP2011511000A5 JP2011511000A5 (enExample) 2013-07-25
JP5599322B2 true JP5599322B2 (ja) 2014-10-01

Family

ID=40932055

Family Applications (9)

Application Number Title Priority Date Filing Date
JP2010545201A Active JP5599322B2 (ja) 2008-01-31 2009-01-30 エクスビボ肺ケアのためのシステムおよび方法
JP2014164178A Active JP6144238B2 (ja) 2008-01-31 2014-08-12 エクスビボ肺ケアのためのシステムおよび方法
JP2015231545A Active JP6483594B2 (ja) 2008-01-31 2015-11-27 エクスビボ肺ケアのためのシステムおよび方法
JP2017047023A Active JP6343696B2 (ja) 2008-01-31 2017-03-13 エクスビボ肺ケアのためのシステムおよび方法
JP2018097232A Active JP6756775B2 (ja) 2008-01-31 2018-05-21 エクスビボ肺ケアのためのシステムおよび方法
JP2020091133A Active JP6887045B2 (ja) 2008-01-31 2020-05-26 エクスビボ肺ケアのためのシステムおよび方法
JP2021083165A Active JP7186825B2 (ja) 2008-01-31 2021-05-17 エクスビボ肺ケアのためのシステムおよび方法
JP2022190532A Active JP7518142B2 (ja) 2008-01-31 2022-11-29 エクスビボ肺ケアのためのシステムおよび方法
JP2024108227A Pending JP2024127996A (ja) 2008-01-31 2024-07-04 エクスビボ肺ケアのためのシステムおよび方法

Family Applications After (8)

Application Number Title Priority Date Filing Date
JP2014164178A Active JP6144238B2 (ja) 2008-01-31 2014-08-12 エクスビボ肺ケアのためのシステムおよび方法
JP2015231545A Active JP6483594B2 (ja) 2008-01-31 2015-11-27 エクスビボ肺ケアのためのシステムおよび方法
JP2017047023A Active JP6343696B2 (ja) 2008-01-31 2017-03-13 エクスビボ肺ケアのためのシステムおよび方法
JP2018097232A Active JP6756775B2 (ja) 2008-01-31 2018-05-21 エクスビボ肺ケアのためのシステムおよび方法
JP2020091133A Active JP6887045B2 (ja) 2008-01-31 2020-05-26 エクスビボ肺ケアのためのシステムおよび方法
JP2021083165A Active JP7186825B2 (ja) 2008-01-31 2021-05-17 エクスビボ肺ケアのためのシステムおよび方法
JP2022190532A Active JP7518142B2 (ja) 2008-01-31 2022-11-29 エクスビボ肺ケアのためのシステムおよび方法
JP2024108227A Pending JP2024127996A (ja) 2008-01-31 2024-07-04 エクスビボ肺ケアのためのシステムおよび方法

Country Status (10)

Country Link
US (7) US9814230B2 (enExample)
EP (2) EP2244773B1 (enExample)
JP (9) JP5599322B2 (enExample)
CN (6) CN101977649B (enExample)
AU (7) AU2009212725B2 (enExample)
CA (5) CA2713443C (enExample)
ES (1) ES2966520T3 (enExample)
IL (7) IL299248B2 (enExample)
NZ (4) NZ586901A (enExample)
WO (1) WO2009099939A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021138715A (ja) * 2008-01-31 2021-09-16 トランスメディックス インコーポレイティッド エクスビボ肺ケアのためのシステムおよび方法

Families Citing this family (119)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8409846B2 (en) 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
EP1768490B1 (en) 2004-10-07 2010-06-09 Transmedics, Inc. Systems and methods for ex-vivo organ care
US9301519B2 (en) 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
IL301141A (en) * 2006-04-19 2023-05-01 Transmedics Inc Systems and methods for ex vivo organ care
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
EP2123320A1 (en) * 2008-05-20 2009-11-25 General Electric Company Arrangement and method for supervising medical monitor
US10091985B2 (en) * 2009-06-18 2018-10-09 Giner, Inc. Perfusing an organ with an in situ generated gas
US9357764B2 (en) 2009-06-18 2016-06-07 Giner, Inc. System for fluid perfusion of biological matter comprising tissue
US20130323708A1 (en) 2009-07-01 2013-12-05 Massachusetts Institute Of Technology Isolated adult cells, artificial organs, rehabilitated organs, research tools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same
WO2011031289A1 (en) * 2009-09-08 2011-03-17 Duke University Novel medical uses for no and no donor compounds
WO2011037512A1 (en) 2009-09-25 2011-03-31 Vivoline Medical Ab Container and supporting structure for housing an organ
US10575515B2 (en) 2010-05-04 2020-03-03 The General Hospital Corporation Methods and compositions for preserving tissues and organs
US9426979B2 (en) 2011-03-15 2016-08-30 Paragonix Technologies, Inc. Apparatus for oxygenation and perfusion of tissue for organ preservation
US9867368B2 (en) 2011-03-15 2018-01-16 Paragonix Technologies, Inc. System for hypothermic transport of samples
US11178866B2 (en) 2011-03-15 2021-11-23 Paragonix Technologies, Inc. System for hypothermic transport of samples
US8828710B2 (en) 2011-03-15 2014-09-09 Paragonix Technologies, Inc. System for hypothermic transport of samples
US12096765B1 (en) 2011-03-15 2024-09-24 Paragonix Technologies, Inc. System for hypothermic transport of samples
US12279610B2 (en) 2011-03-15 2025-04-22 Paragonix Technonogies, Inc. System for hypothermic transport of samples
US9253976B2 (en) 2011-03-15 2016-02-09 Paragonix Technologies, Inc. Methods and devices for preserving tissues
WO2012125782A2 (en) 2011-03-15 2012-09-20 Paragonix Technologies, Inc. Apparatus for oxygenation and perfusion of tissue for organ preservation
CA2830307A1 (en) * 2011-03-23 2012-09-27 Vivoline Medical Ab Apparatus for maintaining a harvested organ viable and transportable
AU2012242578B2 (en) * 2011-04-14 2016-07-21 Transmedics, Inc. Organ care solution for ex-vivo machine perfusion of donor lungs
GB201119420D0 (en) * 2011-11-10 2011-12-21 Organox Ltd Oxygen supply for organ perfusion systems
BR112014011356B1 (pt) 2011-11-10 2021-06-15 Organox Limited Sistema de perfusão para perfundir em um órgão
EP2775829B1 (en) 2011-11-10 2018-07-11 Organox Limited Organ perfusion systems
DE102012112709B4 (de) * 2011-12-30 2022-09-08 Giner Life Sciences, Inc. System zur Fluidperfusion oder Persufflation von biologischem Material, welches Gewebe umfasst
ES2946695T3 (es) 2012-01-17 2023-07-24 Tevosol Inc Aparato para prueba, evaluación, y mantenimiento de corazones extraídos para trasplante
CN104284691B (zh) * 2012-05-11 2017-05-10 皇家飞利浦有限公司 确定通气期间的吸入氧气的分数的系统和方法
US20140017665A1 (en) * 2012-07-10 2014-01-16 Lifeline Scientific, Inc. Organ transporter with oxygen generation
US8785116B2 (en) 2012-08-10 2014-07-22 Paragonix Technologies, Inc. Methods for evaluating the suitability of an organ for transplant
US9560846B2 (en) 2012-08-10 2017-02-07 Paragonix Technologies, Inc. System for hypothermic transport of biological samples
CN102813559B (zh) * 2012-08-27 2014-11-05 山东大学 一种全自动灌流装置
US9795756B2 (en) 2012-12-04 2017-10-24 Mallinckrodt Hospital Products IP Limited Cannula for minimizing dilution of dosing during nitric oxide delivery
HUE032029T2 (en) 2012-12-04 2017-08-28 Ino Therapeutics Llc Cannula for minimizing dilution of dosing during nitric oxide delivery
US10688236B2 (en) * 2013-01-21 2020-06-23 Lxs, Llc Systems and methods for performing medical procedures involving accessing the lymphatic system
US9629358B2 (en) * 2013-03-15 2017-04-25 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids
ES2981406T3 (es) 2013-03-15 2024-10-08 Mallinckrodt Pharmaceuticals Ireland Ltd Administración y monitorización de óxido nítrico en fluidos ex vivo
EP3003025B1 (en) * 2013-06-07 2020-04-08 Perfusion Solutions Pty Ltd Device for use in evaluation, transportation or storage of a donor heart
BR112016006378A2 (pt) 2013-09-24 2017-08-01 Giner Inc sistema para tratamento de gás de um implante de célula
CN103719075B (zh) * 2014-01-14 2015-01-28 吕凌 一种保存离体器官的装置和保存方法
WO2015126853A1 (en) * 2014-02-18 2015-08-27 Baylor College Of Medicine Negative pressure ex vivo lung ventilation and perfusion system
WO2015138832A1 (en) 2014-03-13 2015-09-17 The General Hospital Corporation Devices and methods to improve and assess viability of human livers
CA2942714C (en) * 2014-03-14 2023-09-05 The General Hospital Corporation Lung bioreactor
ES3036002T3 (en) 2014-03-26 2025-09-11 Transmedics Inc Apparatus for maintenance of harvested hearts for transplanting
DK3151663T3 (da) * 2014-06-02 2020-11-30 Transmedics Inc Ex vivo-organplejesystem
AU2015280573A1 (en) * 2014-06-23 2016-08-11 The Armor All/Stp Products Company Cleaning composition having improved vertical cling
EP3194571A4 (en) 2014-09-18 2018-04-18 North Carolina State University Mammalian lung spheroids and lung spheroid cells and uses thereof
USD765874S1 (en) 2014-10-10 2016-09-06 Paragonix Technologies, Inc. Transporter for a tissue transport system
CN105679165A (zh) * 2014-11-18 2016-06-15 复旦大学附属妇产科医院 一种人胎盘体外循环灌注盒
EP3229588B1 (en) * 2014-12-12 2025-04-23 TransMedics, Inc. Apparatus and method for organ perfusion
GB201511220D0 (en) * 2015-06-25 2015-08-12 Xvivo Perfusion Ab Isolated organ evaluation
CA2997267A1 (en) 2015-09-09 2017-03-16 Transmedics, Inc. Aortic cannula for ex vivo organ care system
US20200349863A1 (en) * 2016-02-04 2020-11-05 Xvivo Perfusion Ab Ex vivo lung simulator
US10091986B2 (en) 2016-05-09 2018-10-09 Xor-Labs Toronto Inc. Organ perfusion device and method
CN107183005A (zh) * 2016-05-09 2017-09-22 多伦多Xor-Labs股份有限公司 器官灌注的设备与方法
ES2968062T3 (es) * 2016-05-30 2024-05-07 Transmedics Inc Aparato y método de ventilación pulmonar ex vivo con presión exterior variable
EP3463477A4 (en) 2016-06-07 2020-03-04 NanoPharmaceuticals LLC NON-CLeavable POLYMER CONJUGATED WITH THYROID ANTAGONISTS OF avß3 INTEGRIN
CN109688811B (zh) 2016-07-22 2022-06-03 苏黎世联邦理工学院 用于离体肝灌注的灌注回路组件和肝腔室组件
US20190264153A1 (en) * 2016-07-29 2019-08-29 Juno Therapeutics, Inc. Bioreactor console
AU2017312194A1 (en) * 2016-08-19 2019-04-04 Immunores-Therapeutics, LLC Gas treatment delivery systems and methods
CN106241011B (zh) * 2016-10-18 2018-07-06 宁波高智科技咨询服务有限公司 一种用于病患身体组织转移盛放装置
WO2018093956A1 (en) 2016-11-15 2018-05-24 Giner, Inc. Percutaneous gas diffusion device suitable for use with a subcutaneous implant
EP3541450B1 (en) 2016-11-15 2021-12-29 Giner Life Sciences, Inc. Self-regulating electrolytic gas generator and implant system comprising the same
US10602741B2 (en) 2016-11-28 2020-03-31 Universidad Del Valle Organ-chimerization maintenance apparatus and method of use
DE102016225167B4 (de) 2016-12-15 2018-10-11 Otto-Von-Guericke-Universität Magdeburg Ex vivo-Lungenkreislauf- und Ventilations-Vorrichtung sowie Verfahren zum Training chirurgischer und minimal-invasiver chirurgischer Eingriffe
US20210400952A1 (en) * 2017-06-07 2021-12-30 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
EP3634127B1 (en) 2017-06-07 2024-12-18 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
EP3638019A4 (en) 2017-06-14 2020-08-26 The General Hospital Corporation VERY LOW TEMPERATURE CRYOPRESERVATION
US11881119B2 (en) 2017-12-06 2024-01-23 Cilag Gmbh International Modeling air leaks in lungs
JP2021511339A (ja) * 2018-01-19 2021-05-06 ユニバーシティ オブ メリーランド,ボルチモア 輸送中の人間の臓器を取り扱うための技術
EP3740067B1 (en) 2018-01-19 2024-11-06 ETH Zürich Perfusion loop assembly for an ex-vivo liver perfusion and a method for ex-vivo liver perfusion
US20210001062A1 (en) * 2018-03-08 2021-01-07 University Of Washington Devices, systems, and methods for delivery of a reperfusion-injury-modifying drug to a patient
US10328043B1 (en) 2018-04-11 2019-06-25 Nanopharmaceuticals, Llc. Composition and method for dual targeting in treatment of neuroendocrine tumors
US11351137B2 (en) 2018-04-11 2022-06-07 Nanopharmaceuticals Llc Composition and method for dual targeting in treatment of neuroendocrine tumors
WO2019222704A1 (en) 2018-05-17 2019-11-21 Giner Life Sciences, Inc. Electrolytic gas generator with combined lead and gas port terminals
US11357939B2 (en) * 2018-05-18 2022-06-14 Gyrus Acmi, Inc. Breathing lung device
DE102019111186A1 (de) 2018-05-18 2019-11-21 Spiration, Inc. D/B/A Olympus Respiratory America Lungenbeatmungsvorrichtung
WO2019232268A1 (en) 2018-05-30 2019-12-05 Mustafa Korkut Uygun Cryopreservation of tissues and organs
DE102018118379A1 (de) * 2018-07-30 2020-01-30 Westfälische Wilhelms-Universität Münster MRT geeignetes Herz-Phantom
WO2020102312A1 (en) 2018-11-13 2020-05-22 The Methodist Hospital Method and apparatus for oncomagnetic treatement
RS64992B1 (sr) 2018-12-17 2024-01-31 Gi Cell Inc Blok kopolimer koji sadrži hidrofilni prvi blok, hidrofobni drugi blok i funkcionalnu grupu sposobnu da se specifično vezuje za tiol
CN113453547B (zh) * 2019-01-10 2022-09-20 艾克斯维沃控股有限公司 用于离体测量供体心脏性能的装置和方法
WO2020163596A1 (en) * 2019-02-06 2020-08-13 Belluscura LLC Integrated extracorporeal oxygenation and co2 removal with ventilation system
US20220142528A1 (en) * 2019-02-26 2022-05-12 Obi Aps A method for providing decision support in relation to a patient receiving oxygen treatment
EP3982725A4 (en) 2019-06-11 2023-07-19 Paragonix Technologies Inc. ORGAN TRANSPORT CONTAINER WITH ANTIVIRAL THERAPY
US11324954B2 (en) 2019-06-28 2022-05-10 Covidien Lp Achieving smooth breathing by modified bilateral phrenic nerve pacing
CN110786322B (zh) * 2019-12-09 2025-05-13 无锡市人民医院 离体肺储存灌注装置
US11632951B2 (en) * 2020-01-31 2023-04-25 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
IL323003A (en) * 2020-02-20 2025-10-01 Deka Products Lp System and method for maintaining and transferring a body part
CN111406737B (zh) * 2020-04-24 2021-11-19 润方(北京)生物医药研究院有限公司 用于器官持续维持的成分、装置和方法
US10961204B1 (en) 2020-04-29 2021-03-30 Nanopharmaceuticals Llc Composition of scalable thyrointegrin antagonists with improved blood brain barrier penetration and retention into brain tumors
WO2021224923A1 (en) * 2020-05-05 2021-11-11 Hospitech Respiration Ltd. Fluid distribution device
CN111505666A (zh) * 2020-05-20 2020-08-07 北京市伟业供热设备有限责任公司 用于定位供热设备的系统
WO2021257967A1 (en) 2020-06-19 2021-12-23 The Methodist Hospital Dba Houston Methodist Hospital Method and apparatus for oncomagnetic treatment
JP7645570B2 (ja) 2020-07-16 2025-03-14 ベンテック ライフ システムズ, インコーポレイテッド ガスを濃縮するためのシステムおよび方法
CN116075352A (zh) 2020-07-16 2023-05-05 英瓦卡尔公司 用于浓缩气体的系统和方法
AU2021310289A1 (en) 2020-07-16 2023-03-30 Ventec Life Systems, Inc. System and method for concentrating gas
US11931689B2 (en) 2020-07-16 2024-03-19 Ventec Life Systems, Inc. System and method for concentrating gas
US20220152326A1 (en) * 2020-11-13 2022-05-19 Koninklijke Philips N.V. Lung volume recruitment (lvr) automatic maneuver
CN112106766B (zh) * 2020-11-18 2021-03-12 中山大学附属第一医院 一种离体心肺联合灌注系统及灌注方法
CN112687169B (zh) * 2020-12-17 2022-09-27 杭州堃博生物科技有限公司 一种具有加热功能的肺部固定支撑设备
CN112687143B (zh) * 2020-12-17 2022-09-27 杭州堃博生物科技有限公司 一种具有保温效果的肺部夹持支撑设备
CN112687171B (zh) * 2020-12-17 2022-09-27 杭州堃博生物科技有限公司 一种多功能的肺部夹持支撑设备
CN112687170B (zh) * 2020-12-17 2022-09-27 杭州堃博生物科技有限公司 一种多功能的肺部抵持支撑设备
CN112687144B (zh) * 2020-12-17 2022-09-27 杭州堃博生物科技有限公司 一种帮助肺部收缩扩张的肺部抵持支撑设备
JP7579757B2 (ja) * 2021-06-22 2024-11-08 株式会社Screenホールディングス リーク弁および保存容器
US12347555B2 (en) 2021-07-15 2025-07-01 Ventec Life Systems, Inc. System and method for medical device communication
FR3126283B1 (fr) 2021-08-30 2024-06-21 Stella Surgical Dispositif et procédé de surveillance de greffon
US11723888B2 (en) 2021-12-09 2023-08-15 Nanopharmaceuticals Llc Polymer conjugated thyrointegrin antagonists
USD1031028S1 (en) 2022-09-08 2024-06-11 Paragonix Technologies, Inc. Tissue suspension adaptor
JP2025536201A (ja) * 2022-09-28 2025-11-05 ザ ジェネラル ホスピタル コーポレイション 灌流対象の組織のバイアビリティを特定するためのシステム及び方法
WO2025049335A1 (en) 2023-08-25 2025-03-06 Paragonix Technologies, Inc. Systems and methods for maintaining organ pressure
US20250241295A1 (en) * 2024-01-31 2025-07-31 University Health Network Membrane-less ex vivo lung perfusion
US20250248390A1 (en) 2024-02-02 2025-08-07 Paragonix Technologies, Inc. System for perfusion of an organ
WO2025217569A1 (en) * 2024-04-11 2025-10-16 University Of Massachusetts Conjugated chemically-modified dsrna during ex vivo perfusion of organs
USD1087382S1 (en) 2025-01-30 2025-08-05 Paragonix Technologies, Inc. Device for transporting a biological sample

Family Cites Families (363)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3253595A (en) 1963-08-07 1966-05-31 Cordis Corp Cardiac pacer electrode system
US3468136A (en) 1964-08-25 1969-09-23 Emil S Swenson Method for maintaining organs in a completely viable state
US3406531A (en) 1964-08-25 1968-10-22 Emil S. Swenson Apparatus for maintaining organs in a completely viable state
US3388803A (en) 1965-04-16 1968-06-18 Applied Biolog Sciences Lab In Wearable dialysis apparatus
US3545221A (en) 1967-05-22 1970-12-08 Swenko Research & Dev Inc Apparatus for maintaining organs in vitro in a completely viable state
US3537956A (en) 1967-06-26 1970-11-03 Joseph R Falcone Petrie dish
FR1577356A (enExample) 1968-04-04 1969-08-08
SE323475B (enExample) 1968-11-26 1970-05-04 Aga Ab
US3587567A (en) 1968-12-20 1971-06-28 Peter Paul Schiff Mechanical ventricular assistance assembly
US3545605A (en) 1969-01-24 1970-12-08 Ruth Robins Paint roller package
US3772153A (en) 1969-04-02 1973-11-13 Air Liquide Apparatus for the preservation of animal or human organs in living condition
US3632473A (en) 1969-04-21 1972-01-04 Univ California Method and apparatus for preserving human organs extracorporeally
BE755423A (fr) 1969-10-06 1971-02-01 Baxter Laboratories Inc Procede et appareil pour la conservation d'organes
US3660241A (en) 1970-01-12 1972-05-02 Baxter Laboratories Inc Container for organ perfusion or the like
US3639084A (en) 1970-04-06 1972-02-01 Baxter Laboratories Inc Mechanism for control pulsatile fluid flow
US3881990A (en) 1971-11-24 1975-05-06 Waters Instr Inc Method of transporting and storing organs while retaining the organs in a viable condition
US3777507A (en) 1971-11-24 1973-12-11 Waters Instr Inc Renal preservation system
US3843455A (en) * 1972-09-13 1974-10-22 M Bier Apparatus and technique for preservation of isolated organs through perfusion
US3851646A (en) 1973-04-13 1974-12-03 Sarns Inc Connector for open heart surgery
US3995444A (en) 1974-11-08 1976-12-07 American Hospital Supply Corporation Organ perfusion system
US4004298A (en) 1975-03-31 1977-01-25 Sinai Hospital Of Detroit Magnetically aligned releasable connector
US4069826A (en) 1976-09-03 1978-01-24 Barlow Mfg. Corporation Surgical tube adapter clamp
US4186565A (en) * 1978-05-19 1980-02-05 Henry Ford Hospital Perfusion system for organ preservation
US4231354A (en) 1978-07-14 1980-11-04 Howmedica, Incorporated Pulsatile blood pumping apparatus and method
US4186253A (en) 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method
JPS5710695U (enExample) 1980-06-17 1982-01-20
EP0054635B1 (de) 1980-12-23 1985-02-13 Dr. Franz Köhler Chemie GmbH Protektive Lösung für Herz und Niere und Verfahren zu deren Herstellung
US4801299A (en) 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
JPS60142859A (ja) * 1983-12-29 1985-07-29 泉工医科工業株式会社 拍動血流量自動設定機構付ロ−ラポンプ
US4719201A (en) 1985-02-07 1988-01-12 Regents Of The University Of Minnesota Method for stimulating recovery from ischemia
US4605644A (en) 1985-02-07 1986-08-12 Regents Of The University Of Minnesota Method for stimulating recovery from ischemia employing ribose and adenine
US4666425A (en) * 1985-12-17 1987-05-19 The Dis Corporation Device for perfusing an animal head
DE3614821A1 (de) * 1986-05-02 1987-11-05 Siemens Ag Implantierbare, eichbare messvorrichtung fuer eine koerpersubstanz sowie eichverfahren
US4723939A (en) * 1986-07-31 1988-02-09 The Research Foundation Of State Univ. Of New York Apparatus and method for multiple organ procurement
US4745759A (en) 1986-12-23 1988-05-24 Bauer Dan O Kidney preservation machine
WO1988005261A1 (en) 1987-01-16 1988-07-28 Tops Systems, Inc. Total organ perfusion system
JPS63270601A (ja) 1987-04-30 1988-11-08 Olympus Optical Co Ltd 臓器保存装置
US5051352A (en) 1987-10-07 1991-09-24 The Regents Of The University Of California Apparatus and method of preserving the viability of animal organs
US4847470A (en) 1987-12-14 1989-07-11 Bakke Allan P Electric blood warmer utilizing metallic ribbon flow cartridge and low thermal mass heating units
EP0347923A1 (en) 1988-06-23 1989-12-27 Nicholas J. Perrotta Portable pulsatile organ perfusion device and method
CA2001553A1 (en) 1988-10-26 1990-04-26 Karen Mckelvey Device for transportation of human organs used for transplantation
JPH0499701A (ja) 1988-10-26 1992-03-31 Mckelvey Karen 移植に使用するヒトの臓器の輸送用装置
US4920044A (en) 1988-11-08 1990-04-24 The Cleveland Clinic Foundation Intracellular flush solution for preserving organs
JPH02282301A (ja) 1989-04-24 1990-11-19 Olympus Optical Co Ltd 臓器保存装置
JPH02306901A (ja) 1989-05-19 1990-12-20 Olympus Optical Co Ltd 臟器保存装置
US5326706A (en) 1989-07-17 1994-07-05 Research Foundation Of State University Of New York Homeostatic organ preservation system
JPH0374302A (ja) 1989-08-15 1991-03-28 Olympus Optical Co Ltd 臓器保存装置
JPH0653160B2 (ja) 1989-08-18 1994-07-20 呉羽化学工業株式会社 拍動発生方法及び装置
US5066578A (en) * 1989-12-21 1991-11-19 The Regents Of The University Of California Long-term preservation of organs for transplantation
US5358931A (en) 1990-01-17 1994-10-25 The Regents Of The University Of California Interaction of thermal hysteresis proteins with cells and cell membranes and associated applications
CA2041828A1 (en) 1990-03-05 1992-11-04 Richard L. Lindstrom Viscoelastic solution
US5145771A (en) * 1990-04-12 1992-09-08 The University Of North Carolina At Chapel Hill Rinse solution for organs and tissues
JP2860301B2 (ja) 1990-09-19 1999-02-24 ヘキスト・マリオン・ルセル株式会社 臓器保存用溶液
FR2667297B1 (fr) 1990-09-28 1994-05-27 Electrolux Sarl Conteneur medical climatise.
US5395314A (en) * 1990-10-10 1995-03-07 Life Resuscitation Technologies, Inc. Brain resuscitation and organ preservation device and method for performing the same
US5584804A (en) 1990-10-10 1996-12-17 Life Resuscitation Technologies, Inc. Brain resuscitation and organ preservation device and method for performing the same
US5498427A (en) 1990-11-20 1996-03-12 Pasteur Merieux Serums Et Vaccines Solutions for the perfusion, preservation and reperfusion of organs
FR2672802A1 (fr) 1991-02-15 1992-08-21 Cobe Lab Appareil de mesure de la saturation en oxygene du sang et de l'hematocrite.
US6090776A (en) 1991-03-11 2000-07-18 Creative Bio Molecules, Inc. Morphogen treatment of organ implants
US5381510A (en) 1991-03-15 1995-01-10 In-Touch Products Co. In-line fluid heating apparatus with gradation of heat energy from inlet to outlet
US5157930A (en) 1991-04-22 1992-10-27 Mcghee Samuel C Organ preservation apparatus
US5217860A (en) * 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
US5856081A (en) 1991-07-08 1999-01-05 The American National Red Cross Computer controlled cryoprotectant perfusion apparatus
US5200398A (en) 1991-09-12 1993-04-06 Mount Sinai Hospital Corporation Composition for the preservation of organs comprising glucuronic acid or a physiologically tolerated salt or ester thereof
US5407793A (en) 1991-10-18 1995-04-18 University Of Pittsburgh Of The Commonwealth System Of Higher Education An aqueous heart preservation and cardioplegia solution
JPH0656601B2 (ja) 1991-11-28 1994-07-27 インターナショナル・ビジネス・マシーンズ・コーポレイション データ転送制御用インタフェース回路
DE4201259C2 (de) 1992-01-18 1994-12-08 Sachs Elektronik Kg Hugo Vorrichtung zur Perfusion der Koronargefäße eines isolierten Herzens
US5654266A (en) 1992-02-10 1997-08-05 Chen; Chung-Ho Composition for tissues to sustain viability and biological functions in surgery and storage
US5552267A (en) 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5370989A (en) 1992-04-03 1994-12-06 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5306711A (en) 1992-06-24 1994-04-26 Georgetown University Organ preservative solution
JPH0656601A (ja) 1992-08-07 1994-03-01 Morishita Roussel Kk 移植臓器用の電解質溶液
US5338662A (en) 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
US5354268A (en) 1992-11-04 1994-10-11 Medical Instrument Development Laboratories, Inc. Methods and apparatus for control of vacuum and pressure for surgical procedures
US5356771A (en) * 1993-03-11 1994-10-18 Board Of Regents, The University Of Texas System Combined perfusion and oxygenation organ preservation apparatus
US5362622A (en) * 1993-03-11 1994-11-08 Board Of Regents, The University Of Texas System Combined perfusion and oxygenation apparatus
US5599659A (en) 1993-03-11 1997-02-04 Breonics, Inc. Preservation solution for ex vivo, warm preservation of tissues, explants,organs and vascular endothelial cells comprising retinal-derived fibroblast growth factor, cyclodextrin and chondroitin sulfate
AU6409594A (en) 1993-03-16 1994-10-11 Alliance Pharmaceutical Corporation Preservation solution and method for warm organ preservation
US6461643B2 (en) * 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
JPH06305901A (ja) 1993-04-26 1994-11-01 Akio Kawamura 室温下保存用灌流液およびこれを用いた保存方法
US5385540A (en) * 1993-05-26 1995-01-31 Quest Medical, Inc. Cardioplegia delivery system
US6680305B1 (en) * 1993-06-04 2004-01-20 Biotime, Inc. Physiologically acceptable aqueous solutions and methods for their use
PT701455E (pt) * 1993-06-04 2001-09-27 Biotime Inc Solucao semelhante a plasma
DE9422008U1 (de) 1993-06-07 1997-08-28 Mayer, Berndt, Priv.-Doz. Dr.med., 10585 Berlin Vorrichtung zur Konservierung von Organen, Extremitäten und Gewebelappen
US5405742A (en) 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
ATE218802T1 (de) 1993-08-12 2002-06-15 Univ North Carolina Spüllösung für organe und gewebe
EP2305116A1 (en) 1993-11-05 2011-04-06 ResMed Ltd. Control of CPAP Treatment
DE4342728A1 (de) 1993-12-15 1995-06-22 Thomae Gmbh Dr K Verfahren, Apparate und Perfusionslösungen zur Konservierung explantierter Organe
US5511958A (en) 1994-02-10 1996-04-30 Baxter International, Inc. Blood pump system
US5643712A (en) 1994-05-20 1997-07-01 Brasile; Lauren Method for treating and rendering grafts nonthrombogenic and substantially nonimmunogenic using an extracellular matrix coating
US6375613B1 (en) 1994-05-20 2002-04-23 Breonics, Inc. Prognostic testing of organs intended for transplantation
WO1995031897A1 (en) 1994-05-20 1995-11-30 Vec Tec, Inc. Method and apparatus monitoring viability of transplantable organs
US5505709A (en) * 1994-09-15 1996-04-09 Minimed, Inc., A Delaware Corporation Mated infusion pump and syringe
US5473791A (en) 1994-09-22 1995-12-12 Holcomb; Tim C. Paint roller and tray apparatus
CN2216835Y (zh) * 1994-09-23 1996-01-10 北京卡迪欧医疗器械有限公司 氧合器
JPH0889518A (ja) 1994-09-25 1996-04-09 Terumo Corp 中空器官接続用器具
US5554123A (en) * 1994-10-31 1996-09-10 Glenn Herskowitz Portable infusion pump
US5554497A (en) 1994-12-12 1996-09-10 Charlotte-Mecklenburg Hospital Authority Cardioplegic solution for arresting an organ
CA2207324A1 (en) 1994-12-12 1996-06-20 Richard M. Raymond Organ transplant solutions and method for transplanting an organ
AU711080B2 (en) 1994-12-22 1999-10-07 Regents Of The University Of California, The Method for protecting the heart from ischemia
US5882328A (en) 1995-01-13 1999-03-16 Qlt Phototherapeutics, Inc. Method to prevent transplant rejection
US5656420A (en) 1995-02-24 1997-08-12 University Of Kentucky Research Foundation Method for employing the delta opioid dadle to extend tissue survival time during ischemia
US5586438A (en) 1995-03-27 1996-12-24 Organ, Inc. Portable device for preserving organs by static storage or perfusion
WO1996029865A1 (en) 1995-03-27 1996-10-03 Organ, Inc. Organ evaluation and resuscitation device and method
GB9506312D0 (en) * 1995-03-28 1995-05-17 Medical Res Council Improvements in or relating to sample processing
US5679565A (en) 1995-04-10 1997-10-21 The Regents Of The University Of California Method of preserving pancreatic islets
EP0862474A4 (en) 1995-09-18 2000-05-03 Resmed Ltd PRESSURE CONTROL WITH CPAP TREATMENT OR WITH ASSISTED VENTILATION
DE19535781C2 (de) 1995-09-26 1999-11-11 Fraunhofer Ges Forschung Vorrichtung zur aktiven Strömungsunterstützung von Körperflüssigkeiten
US5759148A (en) 1995-10-18 1998-06-02 Sipin; Anatole J. Controlled pneumatic driving system
US5770149A (en) 1995-10-31 1998-06-23 Baxter International Extracorporeal blood oxygenation system having integrated blood pump, heat exchanger and membrane oxygenator
SE505499C2 (sv) 1995-12-15 1997-09-08 Stiftelsen Facthor Förvaringslösning för organ och vävnad eller delar därav från människor och djur innehållande kalcium och nitroglycerin, användning därav samt förfarande för förvaring därmed
US6794124B2 (en) 1995-12-15 2004-09-21 Stiftelsen Facthor Preservation solution
US5843024A (en) 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US5965433A (en) * 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
US5885328A (en) * 1996-05-31 1999-03-23 Ltv Steel Company, Inc. Method of agglomerating oil-containing steel mill waste
US5716378A (en) 1996-06-06 1998-02-10 Medtronic, Inc. Heart preservation and transportation apparatus and method employing low rate cardiac pacing for improved removal of catabolites from the myocardium
SG48362A1 (en) * 1996-06-25 1998-04-17 Thomas & Betts Corp Single-sided straddle mount printed circuit board connector
US5801442A (en) 1996-07-22 1998-09-01 Northrop Grumman Corporation Microchannel cooling of high power semiconductor devices
US5807737A (en) 1996-07-26 1998-09-15 Schill Enterprises, Inc. Heart and lung support assembly
US5776063A (en) * 1996-09-30 1998-07-07 Molecular Biosystems, Inc. Analysis of ultrasound images in the presence of contrast agent
US6783328B2 (en) * 1996-09-30 2004-08-31 Terumo Cardiovascular Systems Corporation Method and apparatus for controlling fluid pumps
US5787544A (en) * 1996-12-20 1998-08-04 Ppg Industries, Inc. Combined paint package and roller tray
US6642045B1 (en) * 1997-04-14 2003-11-04 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US6217546B1 (en) 1997-05-19 2001-04-17 United States Surgical Corporation Catheter system
WO1998058598A1 (de) 1997-06-21 1998-12-30 Hans Haindl Beutel zur wenigstens teilweisen umfassung eines herzens
US6123725A (en) 1997-07-11 2000-09-26 A-Med Systems, Inc. Single port cardiac support apparatus
WO2005009289A2 (en) 1997-09-03 2005-02-03 Dan Weiner Apparatus and methods for control of intravenous fluids
US6953655B1 (en) 1997-09-23 2005-10-11 The United States Of America As Represented By The Department Of Veterans Affairs Compositions, methods and devices for maintaining an organ
US6100082A (en) 1997-09-23 2000-08-08 Hassanein; Waleed H. Perfusion apparatus and method including chemical compositions for maintaining an organ
DE69819759T2 (de) 1997-09-23 2004-09-23 Hassanein, Waleed H., Malden Zusammensetzungen, verfahren und vorrichtungen zur aufrechterhaltung eines organs
US8409846B2 (en) * 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US6110139A (en) 1997-10-21 2000-08-29 Loubser; Paul Gerhard Retrograde perfusion monitoring and control system
US6352543B1 (en) 2000-04-29 2002-03-05 Ventrica, Inc. Methods for forming anastomoses using magnetic force
DE69807185T2 (de) 1998-04-21 2003-05-08 Guala Dispensing S.P.A., Alessandria Pumpe mit gewölbter Membran für handhebelbetätigte Flüssikeitsspender
GR1003087B (el) 1998-06-30 1999-03-08 Αυτοκαθαριζομενη υδραυλικη τουαλετα για γατες που δεν χρησιμοποιει αμμο υγειας
US6613785B2 (en) 1998-07-21 2003-09-02 Smithkline Beecham Plc Use of glucose uptake enhancer for reducing post-ischemic injury of the heart
US6042550A (en) * 1998-09-09 2000-03-28 Ntc Technology, Inc. Methods of non-invasively estimating intrapulmonary shunt fraction and measuring cardiac output
US6050987A (en) * 1998-09-21 2000-04-18 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Tubular coupling
US7749693B2 (en) * 1998-09-29 2010-07-06 Lifeline Scientific, Inc. Method of determining that an organ is not suitable for transplantation and using it for testing substances
US6977140B1 (en) 1998-09-29 2005-12-20 Organ Recovery Systems, Inc. Method for maintaining and/or restoring viability of organs
EP2308295A3 (en) * 1998-09-29 2011-05-25 Organ Recovery Systems, Inc. Apparatus for transporting an organ
US6673594B1 (en) 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
US7045279B1 (en) 1998-10-22 2006-05-16 Medtronic, Inc. Isolated perfused heart preparation and method of use
DE69922985T2 (de) 1998-10-22 2005-12-15 Medtronic, Inc., Minneapolis Verfahren zur untersuchung an einem isolierten perfundierten herz-präparat
US6587734B2 (en) 1998-11-04 2003-07-01 Acorn Cardiovascular, Inc. Cardio therapeutic heart sack
US6144444A (en) 1998-11-06 2000-11-07 Medtronic Avecor Cardiovascular, Inc. Apparatus and method to determine blood parameters
FR2785501B1 (fr) 1998-11-10 2001-01-05 Centre Nat Rech Scient Solution de perfusion et/ou de conservation et/ou de reperfusion lors de la transplantation d'organes
US6128519A (en) 1998-12-16 2000-10-03 Pepex Biomedical, Llc System and method for measuring a bioanalyte such as lactate
US6168877B1 (en) 1998-12-18 2001-01-02 Aer Energy Resources, Inc. Air-managing system for metal-air battery using resealable septum
US6589223B1 (en) 1999-02-03 2003-07-08 Biotime, Inc. Method and compositions for use in perfusion applications
AU774661B2 (en) * 1999-02-03 2004-07-01 Mermaid Care A/S Automatic lung parameter estimator
WO2000051659A1 (en) 1999-03-05 2000-09-08 Matson Louis R Surface-modified bioactive surgical implants suppressing tissue growth
SE9901056D0 (sv) 1999-03-23 1999-03-23 Pacesetter Ab Sensor system
GB9907372D0 (en) 1999-03-30 1999-05-26 Concentric Pumps Ltd Improvements in pumps
GB9908335D0 (en) 1999-04-12 1999-06-09 Univ Cambridge Tech Methods and means for extracorporeal organ perfusion
US6194137B1 (en) 1999-04-13 2001-02-27 Organ Recovery Systems, Inc. Method of cryopreservation of blood vessels by vitrification
US6582953B2 (en) 1999-04-14 2003-06-24 Breonics, Inc. Organ chamber for exsanguinous metabolic support system
US20070166292A1 (en) * 1999-04-14 2007-07-19 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US20040038192A1 (en) * 1999-04-14 2004-02-26 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US20040038193A1 (en) 1999-04-14 2004-02-26 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US6365338B1 (en) 1999-04-27 2002-04-02 David A. Bull Organ preservative solution containing trehalose, anti-oxidant, cations and an energy source
US20030040665A1 (en) 1999-05-28 2003-02-27 E-Monitors, Inc. Systems and methods of pH tissue monitoring
US6567679B1 (en) * 1999-05-28 2003-05-20 E-Monitors, Inc. Method of using a pH tissue monitor
JP5230042B2 (ja) 1999-06-02 2013-07-10 株式会社ビーエムジー 動物の細胞または臓器の保存剤およびその保存方法。
WO2001001774A1 (en) 1999-06-17 2001-01-11 Regents Of The University Of California Continuous cardiac perfusion preservation with peg-hb for improved hypothermic storage
DE19928485C1 (de) 1999-06-22 2000-10-19 Jostra Medizintechnik Ag Perfusionssystem für menschliche oder tierische Organe oder Körperteile
JP4331869B2 (ja) 1999-06-24 2009-09-16 株式会社根本杏林堂 心拍動下冠動脈バイパス手術用自己血潅流装置
CA2286929A1 (en) 1999-10-18 2001-04-18 Anthony Paolitto Valve surgery apparatus
CN2418882Y (zh) * 1999-10-20 2001-02-14 张国报 离体肺循环灌流新装置
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
US6375611B1 (en) 2000-01-07 2002-04-23 Origin Medsystems, Inc. Organ stabilizer
US6492103B1 (en) 2000-01-31 2002-12-10 Organ Recovery Systems, Inc. System for organ and tissue preservation and hypothermic blood substitution
US6736836B2 (en) 2000-02-17 2004-05-18 The Johns Hopkins University Transplant organ external cooling system
US6811965B2 (en) 2000-03-08 2004-11-02 Yoram Vodovotz Kidney perfusion solution containing nitric oxide donor, inhibitor of NOS2, glutathione, gluconate and methods of use
US6794182B2 (en) 2000-03-13 2004-09-21 E. George Wolf, Jr. Hyperbaric oxygen organ preservation system (HOOPS)
US7611830B2 (en) * 2000-04-10 2009-11-03 The United States Of America As Represented By The Department Of Veteran's Affairs Device to lavage a blood vessel
US6569615B1 (en) 2000-04-10 2003-05-27 The United States Of America As Represented By The Department Of Veteran's Affairs Composition and methods for tissue preservation
US6389308B1 (en) 2000-05-30 2002-05-14 Vladimir Shusterman System and device for multi-scale analysis and representation of electrocardiographic data
US6492745B1 (en) 2000-07-17 2002-12-10 Marconi Communications, Inc. Battery disconnect system
ATE442041T1 (de) * 2000-07-28 2009-09-15 Murphy Christopher J Medium für transplantat
AU2002223180A1 (en) 2000-09-27 2002-04-08 Cobe Cardiovascular, Inc. Blood perfusion system
JP2002119586A (ja) 2000-10-16 2002-04-23 Univ Nihon 血液温冷ないし体温調整方法およびその装置
US6490880B1 (en) 2000-10-26 2002-12-10 Islet Technology Inc. Regulated organ containment shipping system using dual-layer preservation liquid
CN100381048C (zh) 2000-11-03 2008-04-16 维特罗莱夫股份公司 评价和保存溶液
US6602718B1 (en) 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
US20040236170A1 (en) 2000-11-15 2004-11-25 Ducksoo Kim Method for surgically joining a ventricular assist device to the cardiovascular system of a living subject using a piercing introducer assembly
DE60120769T2 (de) 2000-12-21 2007-05-24 Dresser-Rand Co. Zweischichtiger akustischer überzug und fluiddruckbeaufschlagungsvorrichtung
US20020132220A1 (en) 2000-12-27 2002-09-19 Berens Kurt L. Use of selectin antagonists in organ preservation solutions
US6643546B2 (en) * 2001-02-13 2003-11-04 Quetzal Biomedical, Inc. Multi-electrode apparatus and method for treatment of congestive heart failure
US6475716B1 (en) 2001-03-06 2002-11-05 Biobank Co., Ltd. Method for preserving mammalian organs
EP1372916A2 (en) * 2001-03-21 2004-01-02 Vitrox APS Method and housing for performing operations on a material
US20020187132A1 (en) 2001-04-30 2002-12-12 Mcgregor Christopher G.A. Cardiac gene transfer
DE10121159B4 (de) 2001-04-30 2004-01-29 Biederer, Jürgen, Dr. med. Künstlicher Thorax
WO2002089571A1 (en) 2001-05-04 2002-11-14 Breonics, Inc. Organ chamber for exsanguinous metabolic support system
US6894690B2 (en) * 2001-06-20 2005-05-17 Engineering Technology Associates, Inc. Method and apparatus for capturing and viewing a sequence of 3-D images
US6631830B2 (en) * 2001-08-20 2003-10-14 Larami Limited Snap action ball valve assembly and liquid dispenser using same
US6677150B2 (en) 2001-09-14 2004-01-13 Organ Transport Systems, Inc. Organ preservation apparatus and methods
US6924267B2 (en) 2001-09-18 2005-08-02 Suomen Punainen Risti Veripalvelu Methods and active substances for protecting organs
US20030073227A1 (en) 2001-09-28 2003-04-17 Hull Harry F. Simple, fully transportable device for maintaining an excised heart in optimum condition for transplantation
US6609987B1 (en) 2001-10-01 2003-08-26 General Motors Corporation Hydraulic timing chain tensioner assembly
FR2830183B1 (fr) 2001-10-02 2004-06-11 Daniel Roux Prothese aortique avec dispositif rapide de connexion a la circulation extra-corporelle
US6582375B2 (en) 2001-10-11 2003-06-24 University Of Cincinnati System for study of global uni-or bi-ventricular function of an explanted, reperfused heart
JP4213588B2 (ja) 2001-10-12 2009-01-21 ベクトン・ディキンソン・アンド・カンパニー 生体試料を輸送する方法及び装置
US20030074760A1 (en) * 2001-10-19 2003-04-24 Rdk Company Paint applicator system
US6910483B2 (en) 2001-12-10 2005-06-28 Resmed Limited Double-ended blower and volutes therefor
SG108829A1 (en) 2001-12-14 2005-02-28 Agilent Technologies Inc Photo-receiver arrangement
EP1321159A1 (en) 2001-12-21 2003-06-25 CHIESI FARMACEUTICI S.p.A. Pressurized metered dose inhaler (pMDI) actuators with laser drilled orifices
US20030124503A1 (en) 2001-12-28 2003-07-03 Olivencia-Yurvati Albert H. Pyruvate cardioplegia solutions for administration to the heart during cardiopulmonary surgery and methods of use thereof
JP2003206201A (ja) 2001-12-28 2003-07-22 Katsutoshi Naruse 臓器収納装置を含む移植用臓器保存装置および該収納装置を含む人工臓器システム
US6847682B2 (en) * 2002-02-01 2005-01-25 Hughes Electronics Corporation Method, system, device and computer program product for MPEG variable bit rate (VBR) video traffic classification using a nearest neighbor classifier
JP2003315220A (ja) 2002-02-19 2003-11-06 Horiba Ltd 窒素酸化物測定装置
US6878339B2 (en) * 2002-02-19 2005-04-12 Horiba, Ltd. NOx-concentration measuring apparatus
EP2298370B1 (en) 2002-02-21 2013-10-30 Design Mentor, Inc. Fluid pump
AUPS214502A0 (en) 2002-05-06 2002-06-06 Uscom Pty Ltd Blood flow oxygen measurement
AUPS312602A0 (en) 2002-06-21 2002-07-18 James Cook University Organ arrest, protection, preservation and recovery
TW527101U (en) 2002-07-23 2003-04-01 Abit Comp Corp Interface card heat sink
US7572622B2 (en) * 2002-08-14 2009-08-11 Transmedic, Inc. Heart preservation chamber
US6875605B1 (en) 2002-08-21 2005-04-05 Florida State University Research Foundation, Inc. Modular cell culture bioreactor and associated methods
US8361091B2 (en) 2002-08-23 2013-01-29 Organ Recovery Systems, Inc. Cannulas, cannula mount assemblies, and clamping methods using such cannulas and cannula mount assemblies
US20040170950A1 (en) 2002-09-12 2004-09-02 Prien Samuel D. Organ preservation apparatus and methods
EP1553828A4 (en) 2002-09-18 2006-05-17 Lifeblood Medical Inc ORGAN CONSERVATION AND TRANSPORT DEVICE AND METHOD
WO2004034887A2 (en) 2002-10-18 2004-04-29 The General Hospital Corporation Compositions, solutions, and methods used for transplantation
CN1256016C (zh) * 2002-10-29 2006-05-17 陈静瑜 一种用于肺移植的灌洗保存液
WO2004056180A1 (en) 2002-12-23 2004-07-08 Global Cardiac Solutions Pty Ltd Organ preconditioning, arrest, protection, preservation and recovery (1)
US7198751B2 (en) 2003-01-14 2007-04-03 Medtronic, Inc. Disposable, integrated, extracorporeal blood circuit
US20040193096A1 (en) 2003-03-25 2004-09-30 Cooper William Isaac Conceptus chamber
US20050085762A1 (en) 2003-03-31 2005-04-21 Venkataramana Vijay Perfusion circuit for cardiopulmonary bypass with air removal system
ES2885752T3 (es) 2003-04-04 2021-12-15 Organ Recovery Systems Inc Métodos y aparato para perfusión, diagnóstico, almacenamiento y/o transporte de un órgano o tejido
CA2521427C (en) 2003-04-04 2012-11-20 Organ Recovery Systems, Inc. Device for separating gas from a liquid path
JP2004307404A (ja) 2003-04-08 2004-11-04 Nipro Corp 人工酸素運搬体を含む医薬組成物
US20040202993A1 (en) 2003-04-10 2004-10-14 Poo Ramon E. Apparatus and method for organ preservation and transportation
CA2522941A1 (en) 2003-04-23 2004-11-04 Human Biosystems Improved methods and solutions for storing donor organs
EP1475434A1 (en) 2003-05-09 2004-11-10 Oncoscience AG Method for storing tumor cells
CN1233231C (zh) * 2003-05-12 2005-12-28 四川大学华西医院 持续灌注心脏保存装置
CN2616058Y (zh) 2003-05-12 2004-05-19 四川大学华西医院 持续灌注心脏保存装置
CN1849102B (zh) 2003-07-08 2011-01-19 文托技术有限公司 用于主动脉瓣狭窄治疗中通过动脉输送的可植入式修复装置及其方法
WO2005004950A1 (ja) 2003-07-10 2005-01-20 Nikkiso Co., Ltd. 脈拍数測定方法、血圧測定方法、及び血管アクセス監視方法、並びにそれらを用いた医療装置
NL1024022C2 (nl) 2003-07-30 2005-02-01 Technologiestichting Stw Draagbare preservatie-inrichting voor een donororgaan.
DE10340487B4 (de) 2003-09-03 2007-07-12 Technische Universität Dresden Perfusionskreislauf
US20050170019A1 (en) 2003-10-22 2005-08-04 Fred Hutchinson Cancer Research Center Methods, compositions and devices for inducing stasis in cells
BRPI0306282B8 (pt) * 2003-12-26 2021-06-22 Intermed Equipamento Medico Hospitalar Ltda sistema de ventilação em aparelho respiratório
US20050153271A1 (en) 2004-01-13 2005-07-14 Wenrich Marshall S. Organ preservation apparatus and methods
JP3742894B2 (ja) 2004-01-14 2006-02-08 ダイキン工業株式会社 温度制御装置
WO2005074657A2 (en) 2004-02-02 2005-08-18 The General Hospital Corporation Modified organ support devices
US7316666B1 (en) 2004-04-12 2008-01-08 Arizant Healthcare Inc. Fluid warming cassette with rails and a stiffening member
US7390028B2 (en) 2004-05-12 2008-06-24 Blazek Larry M Medical tubing quick disconnect apparatus
US8741555B2 (en) 2004-05-14 2014-06-03 Organ Recovery Systems, Inc. Apparatus and method for perfusion and determining the viability of an organ
ITBO20040434A1 (it) 2004-07-12 2004-10-12 Gd Spa Metodo per la formazione di un pacchetto a portafoglio a coperchio incernierato
CN1989610A (zh) 2004-07-28 2007-06-27 松下电器产业株式会社 振荡器
US20060039870A1 (en) * 2004-08-20 2006-02-23 Turner Jeffrey D Pulmonary delivery of enzymatic medical countermeasures
JP2008511012A (ja) 2004-08-23 2008-04-10 富士フイルム株式会社 樹脂を用いたプラスチック光ファイバの被覆方法及び被覆装置
DE102004048991B4 (de) * 2004-10-04 2010-01-28 Biotronik Crm Patent Ag Elektrodenleitung
AU2016222388B2 (en) 2004-10-07 2017-12-07 Transmedics, Inc. Systems and methods for ex-vivo organ care
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
EP1768490B1 (en) * 2004-10-07 2010-06-09 Transmedics, Inc. Systems and methods for ex-vivo organ care
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9301519B2 (en) * 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
US20060134073A1 (en) * 2004-11-24 2006-06-22 Yoshifumi Naka Compositions and methods for ex vivo preservation of blood vessels for vascular grafts using analogues of cAMP and cGMP
WO2006060309A2 (en) 2004-11-24 2006-06-08 The Trustees Of Columbia University In The City Of New York Compositions and methods for ex vivo preservations of organs
US20090182302A1 (en) 2004-11-30 2009-07-16 Anthony Garabet Method and apparatus for pressurizing a body cavity for diagnostic and rehabilitative purposes
US20090143417A1 (en) 2004-12-24 2009-06-04 The University Of Queensland Methods of treating pain
US20060151950A1 (en) * 2005-01-10 2006-07-13 Puttential Unlimited Two-sided novelty product simulating sport object
US20060160062A1 (en) 2005-01-14 2006-07-20 Young Lindon H Perfusion and/or preservation solution for organs
US20060182722A1 (en) 2005-02-11 2006-08-17 Hering Bernhard J Methods and materials for isolating isogenic islet cells
JP2006305901A (ja) 2005-04-28 2006-11-09 Brother Ind Ltd インクジェット記録装置
US7452711B2 (en) * 2005-05-09 2008-11-18 Victor Daykin Contact plate
AU2006247370A1 (en) 2005-05-12 2006-11-23 University Of Florida Research Foundation, Inc. Materials and methods for regulating blood flow
US9078428B2 (en) * 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
FR2888238B1 (fr) 2005-07-07 2007-09-07 Servier Lab Nouveaux derives 1h-indole-pyridinecarboxamides et 1h-indole-piperidinecarboxamide, leur procede de preparation et les compositions pharceumatiques qui les contiennent.
DE102005048625A1 (de) 2005-10-11 2007-04-12 Universität Leipzig System zur nicht-kardioplegischen Konservierung von Spenderherzen für die Transplantation
US7575856B2 (en) 2005-10-28 2009-08-18 The United States Of America As Represented By The Department Of Veterans Affairs Compositions and methods for the evaluation and resuscitation of cadaveric hearts for transplant
KR20140014318A (ko) 2005-11-17 2014-02-05 니뽄젠야쿠코교 가부시키가이샤 세포 보존용 수용액
EP3067046B1 (en) 2005-12-08 2020-03-25 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections
US7559914B2 (en) 2005-12-14 2009-07-14 Alcon, Inc. Priming a microsurgical system
US20070135760A1 (en) 2005-12-14 2007-06-14 Williams David L Occlusion clearance in microsurgical system
US9598669B2 (en) 2005-12-29 2017-03-21 Anthrogenesis Corporation Composition for collecting placental stem cells and methods of using the composition
BRPI0621229A2 (pt) 2006-01-13 2011-12-06 Smm Medical Ab dispositivo e sistema para tratamento por compressão de uma parte do corpo
IL301141A (en) 2006-04-19 2023-05-01 Transmedics Inc Systems and methods for ex vivo organ care
ES2761938T3 (es) 2006-05-22 2020-05-21 Biovest Int Inc Método y sistema para la producción de células
US20080009815A1 (en) 2006-07-10 2008-01-10 Grabenkort Richard W Vacuum Control System For A Breast Pump
CN2936268Y (zh) * 2006-08-01 2007-08-22 云琛 血液氧合仪
US7321811B1 (en) * 2006-09-14 2008-01-22 Rawls-Meehan Martin B Methods and systems of adjustable bed position control
CA2678486C (en) 2007-02-17 2019-03-12 President And Fellows Of Harvard College Compositions and method for tissue preservation
CN101677526B (zh) 2007-03-01 2014-07-09 生命线科学有限公司 灌注调节
CA2717162A1 (en) 2007-03-02 2008-09-12 Hibernation Therapeutics Limited Transplants
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US20080286746A1 (en) 2007-05-17 2008-11-20 Biorep Technologies, Inc. Perfusion apparatus and method
US20080295839A1 (en) 2007-06-01 2008-12-04 Habashi Nader M Ventilator Apparatus and System of Ventilation
ES2493641T3 (es) * 2007-06-28 2014-09-12 Cydex Pharmaceuticals, Inc. Administración nasal de soluciones acuosas de corticosteroides
CL2008003784A1 (es) 2007-12-17 2009-08-14 Medical Research Council Tech Anticuerpo humanizado anti proteina e2 del virus de la hepatitis c o un fragmento de union; acido nucleico que lo codifica; vector y celula huesped que comprenden dicho acido nucleico; metodo para producir el anticuerpo; composicion farmaceutica que comprende el anticuerpo
US9814230B2 (en) 2008-01-31 2017-11-14 Transmedics, Inc. Systems and methods for ex vivo lung care
WO2009136838A1 (en) 2008-05-06 2009-11-12 Igelösa Transplantation Science Ab Apparatus for housing an organ during evaluation and preservation
US8329450B2 (en) 2008-08-01 2012-12-11 Biomedinnovations, Llc Methods and apparatus for organ support
US20110177487A1 (en) 2008-09-23 2011-07-21 Cedars-Sinai Medical Center Methods and apparatus for perfusion of an explanted donor heart
US9113624B2 (en) 2008-10-15 2015-08-25 Covidien Lp System and method for perfusing biological organs
US20120064050A1 (en) 2009-02-04 2012-03-15 Yale University Tissue Engineering of Lung
US8167869B2 (en) 2009-02-10 2012-05-01 Tyco Healthcare Group Lp Wound therapy system with proportional valve mechanism
GB0903299D0 (en) 2009-02-26 2009-04-08 Guys And St Thomas Nhs Foundat Composition and methods
JP5453918B2 (ja) 2009-05-18 2014-03-26 トヨタ自動車株式会社 流量制御弁
JP5246425B2 (ja) 2009-05-19 2013-07-24 株式会社Ihi 航空機用ジェットエンジンの騒音低減装置と方法
JP5906184B2 (ja) 2009-06-22 2016-04-20 バーナム インスティテュート フォー メディカル リサーチ C末端エレメントを有するペプチドおよびタンパク質を使用する方法および組成物
US8337783B2 (en) 2009-06-23 2012-12-25 The United States of America as represented by the Secretary of Commerce, the National Institute of Standards and Technology Magnetic connectors for microfluidic applications
US20130323708A1 (en) 2009-07-01 2013-12-05 Massachusetts Institute Of Technology Isolated adult cells, artificial organs, rehabilitated organs, research tools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same
SE534527C2 (sv) 2009-09-24 2011-09-20 Vivoline Medical Ab Förfarande, anordning och vätska för behandling av ett hjärta efter uttagning
US8685709B2 (en) 2009-09-25 2014-04-01 Board Of Regents Of The University Of Texas System Fluidics based pulsatile perfusion preservation device and method
US9320269B2 (en) 2009-09-25 2016-04-26 John Brassil Organ preservation system
WO2011072012A2 (en) 2009-12-08 2011-06-16 Vanderbilt University Improved methods and compositions for vein harvest and autografting
US20110294108A1 (en) 2010-05-28 2011-12-01 Tyco Healthcare Group Lp System and Method for an Ex Vivo Body Organ Electrosurgical Research Device
EP2588176B1 (en) 2010-07-02 2016-08-24 Koninklijke Philips N.V. System for performing respiratory diagnostics
US8715305B2 (en) 2010-09-03 2014-05-06 The Board Of Regents Of The University Of Texas Systems Magnetic ventricular connector
PT2621569T (pt) 2010-09-28 2017-07-14 B&D Electromedical Ltd Dispositivo de tratamento
CA2830307A1 (en) 2011-03-23 2012-09-27 Vivoline Medical Ab Apparatus for maintaining a harvested organ viable and transportable
AU2012242578B2 (en) 2011-04-14 2016-07-21 Transmedics, Inc. Organ care solution for ex-vivo machine perfusion of donor lungs
US9642625B2 (en) 2011-04-29 2017-05-09 Lifeline Scientific, Inc. Cannula for a donor organ with or without an aortic cuff or patch
FR2975869B1 (fr) 2011-05-31 2017-03-03 Hemarina Composition de preservation d'organe et utilisations
US20120330438A1 (en) 2011-06-22 2012-12-27 Shaf Keshavjee Repaired organ and method for making the same
CA2847368C (en) 2011-09-02 2017-10-31 Organ Assist B.V. Apparatus, system and method for conditioning and preserving an organ from a donor
US9127694B2 (en) 2011-09-09 2015-09-08 Woodward, Inc. High-flow electro-hydraulic actuator
GB201119420D0 (en) 2011-11-10 2011-12-21 Organox Ltd Oxygen supply for organ perfusion systems
EP2775829B1 (en) 2011-11-10 2018-07-11 Organox Limited Organ perfusion systems
BR112014011356B1 (pt) 2011-11-10 2021-06-15 Organox Limited Sistema de perfusão para perfundir em um órgão
JP6189316B2 (ja) 2011-11-23 2017-08-30 ケーシーアイ ライセンシング インコーポレイテッド 複数の組織部位を同時に治療する負圧システム、方法および機器
ES2946695T3 (es) 2012-01-17 2023-07-24 Tevosol Inc Aparato para prueba, evaluación, y mantenimiento de corazones extraídos para trasplante
US20140315175A1 (en) 2012-01-24 2014-10-23 Pulmonx Corporation System for simulating lung function
AU2013278027B2 (en) 2012-06-21 2017-06-15 Fiskars Finland Oy Ab Quick connect and quick disconnect system and method of manipulating a quick connect and quick disconnect system
US9565853B2 (en) 2012-07-10 2017-02-14 Lifeline Scientific, Inc. Perfusion apparatus with reduced pressure fluctuations, and bubble trap
US9402389B2 (en) 2012-07-10 2016-08-02 Lifeline Scientific, Inc. Organ transport apparatus with sample compartments
US8814889B2 (en) 2012-07-10 2014-08-26 Lifeline Scientific, Inc. Cannula with floating clamp member
US10602740B2 (en) 2012-07-10 2020-03-31 Lifeline Scientific, Inc. Organ perfusion apparatus with downstream flow control
US9259562B2 (en) 2012-07-10 2016-02-16 Lifeline Scientific, Inc. Cannula
GB201216928D0 (en) 2012-09-21 2012-11-07 I2R Medical Ltd Portable medical device system
WO2014059316A1 (en) 2012-10-12 2014-04-17 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Compositions and methods for organ preservation
US9629977B2 (en) 2012-11-09 2017-04-25 Carefusion 303, Inc. Capping device for a medical access connector
CA2905994C (en) 2013-03-15 2022-01-04 Ino Therapeutics Llc Therapeutic gas delivery device with pulsed and continuous flow control
US9629358B2 (en) 2013-03-15 2017-04-25 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids
EP3003025B1 (en) 2013-06-07 2020-04-08 Perfusion Solutions Pty Ltd Device for use in evaluation, transportation or storage of a donor heart
SE538477C2 (sv) 2013-10-24 2016-07-19 Vivoline Medical Ab Anordning för undersökning av ett isolerat slående hjärta
CN203724222U (zh) 2014-01-20 2014-07-23 辽宁中医药大学 大动物离体工作心双通道灌流实验设备
WO2015126853A1 (en) 2014-02-18 2015-08-27 Baylor College Of Medicine Negative pressure ex vivo lung ventilation and perfusion system
CA2939115A1 (en) 2014-02-28 2015-09-03 Bdbc Sciences Corp. A system for tissue manipulation
WO2015138832A1 (en) 2014-03-13 2015-09-17 The General Hospital Corporation Devices and methods to improve and assess viability of human livers
CA2942714C (en) 2014-03-14 2023-09-05 The General Hospital Corporation Lung bioreactor
ES3036002T3 (en) 2014-03-26 2025-09-11 Transmedics Inc Apparatus for maintenance of harvested hearts for transplanting
JP6580329B2 (ja) 2014-03-31 2019-09-25 シスメックス株式会社 未分化細胞から分化細胞および/または分化細胞の産生物を取得する方法
CN107734967B (zh) 2014-04-10 2021-07-16 体沃索股份有限公司 在获得的可移植的心脏中调节钙离子稳态
CA2945189C (en) 2014-04-10 2022-10-11 Quanser Consulting Inc. Robotic systems and methods of operating robotic systems
US10433539B2 (en) 2014-04-10 2019-10-08 Tevosol, Inc. Composition and solution with controlled calcium ion level, and related method and use for reperfusion
EP3128932B1 (en) 2014-04-10 2024-09-04 University Health Network Cannula for connecting medical devices to biological systems
CN103893205B (zh) 2014-04-15 2016-03-09 青岛大学附属医院 一种包含利多卡因和腺苷的心脏停搏液及其制备方法
DK3151663T3 (da) 2014-06-02 2020-11-30 Transmedics Inc Ex vivo-organplejesystem
AU2015336862B2 (en) 2014-10-24 2018-08-09 Transmedics, Inc. Novel composition and solution with controlled calcium ion level, and related method and use for reperfusion
EP3229588B1 (en) 2014-12-12 2025-04-23 TransMedics, Inc. Apparatus and method for organ perfusion
US10124093B1 (en) 2015-01-16 2018-11-13 Kci Licensing, Inc. System and method for hybrid control of reduced pressures delivered to a tissue site
CN104770361B (zh) 2015-03-11 2017-05-17 浙江大学 肝移植术中供肝快速固定灌注装置
CA2997267A1 (en) 2015-09-09 2017-03-16 Transmedics, Inc. Aortic cannula for ex vivo organ care system
EP3370518B1 (en) 2015-10-14 2023-08-23 X-Therma, Inc. Compositions and methods for reducing ice crystal formation
ES2968062T3 (es) 2016-05-30 2024-05-07 Transmedics Inc Aparato y método de ventilación pulmonar ex vivo con presión exterior variable
SE542143C2 (en) 2016-10-14 2020-03-03 Nordhydraulic Ab Actuator linkage assembly
US11700848B2 (en) 2017-11-20 2023-07-18 Tevosol, Inc. Apparatus for perfusion of an excised organ
US11632951B2 (en) 2020-01-31 2023-04-25 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
IL323003A (en) 2020-02-20 2025-10-01 Deka Products Lp System and method for maintaining and transferring a body part
IL302230A (en) 2020-10-19 2023-06-01 Oxiteno S A Ind?Stria E Com?Rcio Composition, agrochemical formulation, methods for increasing water and nutrient availability and for improving pest control in plants and seeds, and the agrochemical formulation
WO2024076971A1 (en) 2022-10-03 2024-04-11 Transmedics, Inc. Valve assembly and ventilator with spools for proportional fluid flow control

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021138715A (ja) * 2008-01-31 2021-09-16 トランスメディックス インコーポレイティッド エクスビボ肺ケアのためのシステムおよび方法
JP7186825B2 (ja) 2008-01-31 2022-12-09 トランスメディックス インコーポレイティッド エクスビボ肺ケアのためのシステムおよび方法

Also Published As

Publication number Publication date
CN103430939A (zh) 2013-12-11
US8420380B2 (en) 2013-04-16
JP2020138976A (ja) 2020-09-03
IL282647B (en) 2022-03-01
NZ753880A (en) 2020-12-18
AU2021282426A1 (en) 2021-12-23
CA2713443A1 (en) 2009-08-13
AU2009212725A1 (en) 2009-08-13
CA2713443C (en) 2018-11-13
US9462802B2 (en) 2016-10-11
AU2019213360A1 (en) 2019-08-29
US20090197325A1 (en) 2009-08-06
IL299248A (en) 2023-02-01
JP2024127996A (ja) 2024-09-20
US20090197240A1 (en) 2009-08-06
AU2014202736B2 (en) 2017-07-20
CN105494312A (zh) 2016-04-20
CN105494312B (zh) 2019-03-29
US20090197324A1 (en) 2009-08-06
CN108402030B (zh) 2022-03-01
IL304036B1 (en) 2024-11-01
JP2015007083A (ja) 2015-01-15
JP2017105839A (ja) 2017-06-15
JP7186825B2 (ja) 2022-12-09
WO2009099939A2 (en) 2009-08-13
IL304036B2 (en) 2025-03-01
CN108402030A (zh) 2018-08-17
CN112438251A (zh) 2021-03-05
NZ739110A (en) 2019-08-30
US9814230B2 (en) 2017-11-14
US20090197241A1 (en) 2009-08-06
US20130157248A1 (en) 2013-06-20
IL264199B (en) 2021-05-31
HK1192115A1 (zh) 2014-08-15
JP2021138715A (ja) 2021-09-16
US9516875B2 (en) 2016-12-13
EP2244773A2 (en) 2010-11-03
IL304036A (en) 2023-08-01
IL290501B2 (en) 2023-06-01
IL315867A (en) 2024-11-01
CA3015816A1 (en) 2009-08-13
NZ586901A (en) 2013-04-26
AU2023203083A1 (en) 2023-06-08
CA2899880A1 (en) 2009-08-13
JP6144238B2 (ja) 2017-06-07
CA2899880C (en) 2019-08-20
NZ724681A (en) 2018-08-31
CN116267894A (zh) 2023-06-23
EP4331362A3 (en) 2024-05-01
IL247534B (en) 2019-02-28
AU2014202736A1 (en) 2014-06-12
CA2948767C (en) 2020-03-31
JP2011511000A (ja) 2011-04-07
JP2016033154A (ja) 2016-03-10
JP2018123171A (ja) 2018-08-09
AU2017204594B2 (en) 2019-08-01
AU2023203083B2 (en) 2025-07-24
AU2017204594A1 (en) 2017-07-27
IL264199A (en) 2019-02-28
US12317888B2 (en) 2025-06-03
CA3015816C (en) 2022-12-13
AU2017204594C1 (en) 2020-07-09
AU2009212725B2 (en) 2015-02-26
EP2244773A4 (en) 2014-06-25
CN101977649A (zh) 2011-02-16
CN101977649B (zh) 2014-02-19
IL299248B2 (en) 2023-12-01
JP2023014199A (ja) 2023-01-26
JP6887045B2 (ja) 2021-06-16
US10750738B2 (en) 2020-08-25
CN112438251B (zh) 2023-03-14
AU2014202736C1 (en) 2020-07-09
US9247728B2 (en) 2016-02-02
AU2019213360B2 (en) 2021-09-09
JP6756775B2 (ja) 2020-09-16
EP2244773B1 (en) 2023-11-15
IL290501A (en) 2022-04-01
JP7518142B2 (ja) 2024-07-17
EP4331362A2 (en) 2024-03-06
IL299248B1 (en) 2023-08-01
CN103430939B (zh) 2016-01-06
HK1217607A1 (zh) 2017-01-20
ES2966520T3 (es) 2024-04-22
AU2021282426B2 (en) 2023-02-23
US20200352155A1 (en) 2020-11-12
CA3176645A1 (en) 2009-08-13
CA2948767A1 (en) 2009-08-13
WO2009099939A3 (en) 2009-12-30
US20090197292A1 (en) 2009-08-06
IL282647A (en) 2021-06-30
JP6483594B2 (ja) 2019-03-13
NZ623220A (en) 2015-11-27
JP6343696B2 (ja) 2018-06-13
AU2025256230A1 (en) 2025-11-13

Similar Documents

Publication Publication Date Title
JP7518142B2 (ja) エクスビボ肺ケアのためのシステムおよび方法
JP2011511000A5 (enExample)
HK1217607B (zh) 用於离体肺护理的系统和方法
HK1150235A (en) Systems and methods for ex vivo lung care
HK1150235B (en) Systems and methods for ex vivo lung care

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20120125

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20120125

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130125

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130508

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20130508

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130531

A524 Written submission of copy of amendment under article 19 pct

Free format text: JAPANESE INTERMEDIATE CODE: A524

Effective date: 20130531

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20130628

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20130801

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131031

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131108

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131127

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20131204

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20131224

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20140107

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20140115

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20140714

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20140812

R150 Certificate of patent or registration of utility model

Ref document number: 5599322

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250