DK3151663T3 - Ex vivo-organplejesystem - Google Patents

Ex vivo-organplejesystem Download PDF

Info

Publication number
DK3151663T3
DK3151663T3 DK15803127.8T DK15803127T DK3151663T3 DK 3151663 T3 DK3151663 T3 DK 3151663T3 DK 15803127 T DK15803127 T DK 15803127T DK 3151663 T3 DK3151663 T3 DK 3151663T3
Authority
DK
Denmark
Prior art keywords
care system
organ care
vivo organ
vivo
organ
Prior art date
Application number
DK15803127.8T
Other languages
English (en)
Inventor
Waleed H Hassanein
Jeff Barnes
Greg Ritchie
Richard Bringham
Mark Anderson
John Sullivan
Ahmed Elbetanony
Tamer I Khayal
Original Assignee
Transmedics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transmedics Inc filed Critical Transmedics Inc
Application granted granted Critical
Publication of DK3151663T3 publication Critical patent/DK3151663T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/14Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142Apparatus
    • A01N1/143Apparatus for organ perfusion
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/10Perfusion

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Eye Examination Apparatus (AREA)
DK15803127.8T 2014-06-02 2015-06-02 Ex vivo-organplejesystem DK3151663T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201462006878P 2014-06-02 2014-06-02
US201462006871P 2014-06-02 2014-06-02
PCT/US2015/033839 WO2015187737A1 (en) 2014-06-02 2015-06-02 Ex vivo organ care system

Publications (1)

Publication Number Publication Date
DK3151663T3 true DK3151663T3 (da) 2020-11-30

Family

ID=54700285

Family Applications (1)

Application Number Title Priority Date Filing Date
DK15803127.8T DK3151663T3 (da) 2014-06-02 2015-06-02 Ex vivo-organplejesystem

Country Status (10)

Country Link
US (5) US10076112B2 (da)
EP (1) EP3151663B1 (da)
JP (4) JP2017518301A (da)
CN (2) CN106659151B (da)
AU (3) AU2015271799B2 (da)
CA (2) CA3185937A1 (da)
DK (1) DK3151663T3 (da)
ES (1) ES2839202T3 (da)
IL (6) IL303658B2 (da)
WO (1) WO2015187737A1 (da)

Families Citing this family (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7651835B2 (en) 2004-10-07 2010-01-26 Transmedics, Inc. Method of timing pulsatile flow of normothermic perfusate to the heart
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US10750738B2 (en) 2008-01-31 2020-08-25 Transmedics, Inc. Systems and methods for ex vivo lung care
US12279610B2 (en) 2011-03-15 2025-04-22 Paragonix Technonogies, Inc. System for hypothermic transport of samples
US12096765B1 (en) 2011-03-15 2024-09-24 Paragonix Technologies, Inc. System for hypothermic transport of samples
NZ616699A (en) 2011-04-14 2016-03-31 Transmedics Inc Organ care solution for ex-vivo machine perfusion of donor lungs
IL303658B2 (en) 2014-06-02 2024-07-01 Transmedics Inc Ex vivo organ care system
ES2957211T3 (es) 2014-09-02 2024-01-15 United Therapeutics Corp Sistema de biorreactor automatizado para la descelularización de un órgano
CN107110931B (zh) 2014-09-05 2020-09-22 海珀菲纳研究股份有限公司 用于磁共振成像的铁磁增强系统及提供该系统的方法
US10813564B2 (en) 2014-11-11 2020-10-27 Hyperfine Research, Inc. Low field magnetic resonance methods and apparatus
CA2970117A1 (en) 2014-12-12 2016-06-16 Darren FREED Apparatus and method for organ perfusion
USD800772S1 (en) * 2015-09-04 2017-10-24 Jaguar Land Rover Limited Display screen or portion thereof with icon
AU2016318622B2 (en) 2015-09-09 2021-05-20 Transmedics, Inc. Aortic cannula for ex vivo organ care system
AU2016334242B2 (en) * 2015-10-09 2020-09-24 Deka Products Limited Partnership Fluid pumping and bioreactor system
US20170170979A1 (en) * 2015-12-15 2017-06-15 Pentair Flow Technologies, Llc Systems and Methods for Wireless Control and Monitoring of Residential Devices
US20190141988A1 (en) * 2016-05-20 2019-05-16 SCREEN Holdings Co., Ltd. Perfusion device for liver graft, and liver removal method and liver transplantation method using the device
ES2968062T3 (es) 2016-05-30 2024-05-07 Transmedics Inc Aparato y método de ventilación pulmonar ex vivo con presión exterior variable
WO2018015548A2 (en) 2016-07-22 2018-01-25 ETH Zürich Perfusion loop assembly for an ex-vivo liver perfusion and a liver chamber assembly
US11617832B2 (en) 2016-08-17 2023-04-04 International Business Machines Corporation Portal system-based bionic pancreas
WO2018037835A1 (ja) * 2016-08-25 2018-03-01 株式会社Screenホールディングス 肝臓保存方法及び手術方法
US11282602B2 (en) 2016-10-26 2022-03-22 Carefusion 2200, Inc. Device and method for mobile monitoring of drainage catheter
US11299705B2 (en) 2016-11-07 2022-04-12 Deka Products Limited Partnership System and method for creating tissue
KR20190087455A (ko) 2016-11-22 2019-07-24 하이퍼파인 리서치, 인크. 자기 공명 이미지들에서의 자동화된 검출을 위한 시스템들 및 방법들
US10539637B2 (en) 2016-11-22 2020-01-21 Hyperfine Research, Inc. Portable magnetic resonance imaging methods and apparatus
US10585153B2 (en) 2016-11-22 2020-03-10 Hyperfine Research, Inc. Rotatable magnet methods and apparatus for a magnetic resonance imaging system
US10627464B2 (en) 2016-11-22 2020-04-21 Hyperfine Research, Inc. Low-field magnetic resonance imaging methods and apparatus
ES2675882B1 (es) * 2017-01-12 2019-04-26 Ebers Medical Tech S L Equipo de perfusion de organos
US10684616B2 (en) * 2017-01-27 2020-06-16 Preston Industries, Inc. Self-test system for qualifying refrigeration chiller system performance
FR3067220B1 (fr) * 2017-06-13 2019-07-26 Centre National De La Recherche Scientifique Dispositif de perfusion d'un organe
CN107183009B (zh) * 2017-06-14 2018-05-15 广州军区广州总医院 离体肝脏机械灌注系统
US10570362B2 (en) * 2017-07-12 2020-02-25 Deka Products Limited Partnership System and method for transferring tissue
ES3019687T3 (en) * 2017-11-20 2025-05-21 Transmedics Inc Device and kit for supporting and connecting an excised organ
WO2019141809A1 (en) 2018-01-19 2019-07-25 ETH Zürich Perfusion loop assembly for an ex-vivo liver perfusion and a method for ex-vivo liver perfusion
EP3513653A1 (en) 2018-01-19 2019-07-24 ETH Zürich Perfusion loop assembly for an ex-vivo liver perfusion and a method for ex-vivo liver perfusion
CN108157352A (zh) * 2018-02-11 2018-06-15 广东顺德工业设计研究院(广东顺德创新设计研究院) 多器官一体灌注设备
US20190266922A1 (en) * 2018-02-24 2019-08-29 Justin Michael Lemieux Active Cadaver Systems and Methods for Medical Simulations
EP3764883A4 (en) * 2018-03-12 2021-12-15 North Carolina State University VASCULAR DEVELOPMENT MONITORING SYSTEMS AND THEIR USES
BR112020021872A2 (pt) 2018-05-21 2021-01-26 Hyperfine Research, Inc. métodos e aparelhos de magneto b0 para um sistema de ressonância magnética
WO2019241499A1 (en) 2018-06-13 2019-12-19 Miromatrix Medical Inc. Fistula filler and deployment system
JP2020007297A (ja) * 2018-06-27 2020-01-16 株式会社Screenホールディングス 灌流装置および灌流方法
USD879316S1 (en) * 2018-07-10 2020-03-24 Spiration, Inc. Lung box
US20200108109A1 (en) * 2018-10-05 2020-04-09 Duke University Methods for the Delivery of Therapeutic Agents to Donor Organs
US12186575B2 (en) 2018-11-13 2025-01-07 The Methodist Hospital Method and apparatus for oncomagnetic treatment
JP2020083785A (ja) * 2018-11-19 2020-06-04 株式会社Screenホールディングス 臓器保存装置および臓器保存方法
USD879317S1 (en) * 2018-12-20 2020-03-24 Spiration, Inc. Lung box
ES3019584T3 (en) * 2019-01-10 2025-05-20 Xvivo Holding B V An apparatus and a method for ex-vivo measurement of performance of a donor heart
CN109730054B (zh) * 2019-01-30 2021-09-21 广东丁沃生医疗器械有限公司 一种用于肝脏灌注的气体输送系统
CN110459113A (zh) * 2019-03-22 2019-11-15 天一阁医疗科技(广州)有限公司 一种器官灌注教学培训系统
CN110432260A (zh) * 2019-03-22 2019-11-12 天一阁医疗科技(广州)有限公司 一种生物体器官的机械灌注保存装置
EP3982725A4 (en) 2019-06-11 2023-07-19 Paragonix Technologies Inc. ORGAN TRANSPORT CONTAINER WITH ANTIVIRAL THERAPY
JP7278898B2 (ja) * 2019-07-25 2023-05-22 株式会社Screenホールディングス 灌流装置
CN110313469B (zh) * 2019-08-07 2020-09-01 上海大学 一种用于离体心脏灌注的后负载装置
CN112969926B (zh) 2019-08-28 2022-10-28 汽车服务集团有限责任公司 用于高级驾驶员辅助特征的维护和修理系统
JP7355567B2 (ja) * 2019-09-11 2023-10-03 株式会社Screenホールディングス 臓器収容容器
CN110663680A (zh) * 2019-10-25 2020-01-10 上海长海医院 一种供肾的机器灌注保存及转运仪器
EP4051107A4 (en) 2019-10-28 2023-11-01 The Research Foundation for The State University of New York DEVICES, SYSTEMS AND METHODS FOR MONITORING ARTERIAL CARBON DIOXIDE
US11632951B2 (en) 2020-01-31 2023-04-25 Paragonix Technologies, Inc. Apparatus for tissue transport and preservation
CN115605086B (zh) * 2020-02-12 2024-11-05 泰恩河畔纽卡斯尔大学 装置和方法
WO2021183527A1 (en) * 2020-03-12 2021-09-16 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Systems, methods, and devices for ex vivo analysis of resected tissue samples
US11974568B2 (en) * 2020-03-20 2024-05-07 The Cleveland Clinic Foundation Portable, ex vivo, normothermic limb perfusion machine
US20210315200A1 (en) * 2020-04-14 2021-10-14 Miromatrix Medical Inc. System for functional testing and transportation of biologically engineered organs
ES2869454A1 (es) * 2020-04-24 2021-10-25 Ebers Medical Tech S L Dispositivo de perfusion normotermica adaptado para mantener en condiciones fisiologicas optimas un higado o un rinon
EP4168108A4 (en) 2020-06-19 2024-07-17 The Methodist Hospital dba Houston Methodist Hospital METHOD AND APPARATUS FOR ONCOMAGNETIC TREATMENT
US12052986B2 (en) * 2020-07-08 2024-08-06 Vascular Perfusion Solutions, Inc. Portable oxygen source with perfusion system
JP7527146B2 (ja) * 2020-07-21 2024-08-02 株式会社Screenホールディングス 臓器保存装置
CN111657271B (zh) * 2020-07-30 2024-04-09 无锡市人民医院 医用离体器官机械灌注设备及其屏幕挂杆装置
CN111903664A (zh) * 2020-08-17 2020-11-10 广东顺德工业设计研究院(广东顺德创新设计研究院) 离体器官灌注系统及储肝器
IT202000023311A1 (it) * 2020-10-02 2022-04-02 Aferetica S R L Sistema di perfusione ex vivo di un organo e relativo metodo di controllo della pressione e del flusso del liquido di perfusione del sistema di perfusione ex vivo di un organo
CN114342918B (zh) * 2021-02-08 2023-01-17 苏州心擎医疗技术有限公司 温血器官转运平台及排气方法
ES2921361B2 (es) * 2021-02-16 2023-05-08 Ebers Medical Tech S L Dispositivo de perfusion modular y versatil para preservar un organo en condiciones de operacion regulables
US20240156081A1 (en) * 2021-03-25 2024-05-16 Vanderbilt University Veno-arterial venous cross-circulation for extracorporeal organ support
JP2022167516A (ja) 2021-04-23 2022-11-04 株式会社Screenホールディングス 蓋装置および容器減圧方法
US11432538B1 (en) * 2021-05-05 2022-09-06 The Florida International University Board Of Trustees Blood-feeding systems and methods for hematophagous arthropods
CN113498775A (zh) * 2021-06-11 2021-10-15 首都医科大学宣武医院 可变温度的离体器官机械灌注系统
US12439910B2 (en) * 2021-06-28 2025-10-14 John M. Brassil Apparatus and method for sustaining and evaluating isolated organs
WO2023025948A1 (en) * 2021-08-27 2023-03-02 Medtronic Ireland Manufacturing Unlimited Company Mimicking physiologic conditions during organ or tissue perfusion
US20230078184A1 (en) * 2021-09-16 2023-03-16 Hewlett-Packard Development Company, L.P. Transmissions of secure activities
WO2023044014A1 (en) * 2021-09-17 2023-03-23 Yale University Methods, systems and compositions for restoration and preservation of intact organs in a mammal
USD1050169S1 (en) * 2021-11-05 2024-11-05 Thor Tech, Inc. Display screen or portion thereof with a transitional graphical user interface
JP2023084756A (ja) * 2021-12-08 2023-06-20 株式会社Screenホールディングス 臓器保存装置および臓器保存方法
CN113994954A (zh) * 2021-12-10 2022-02-01 广东省虚拟医学科技有限公司 一种器官离体灌注装置
AU2023209887A1 (en) * 2022-01-21 2024-08-15 Trisalus Life Sciences, Inc. Methods of treating immune dysfunction in liver cancer with toll-like receptor agonists
WO2023164217A1 (en) * 2022-02-25 2023-08-31 Advanced Solutions Life Sciences, Llc Bioreactor assemblies, perfusion bioreactor systems, and methods
CA231191S (en) * 2022-03-17 2024-08-09 Deka Products Lp Tissue maintenance and assessment device tissue retaining strap
EP4507492A1 (en) * 2022-04-11 2025-02-19 Institut National de la Santé et de la Recherche Médicale Method and apparatus for ultrasonic evaluation of an isolated organ
CN114600872A (zh) * 2022-04-13 2022-06-10 西安北光医学生物技术有限公司 一种细胞、组织或器官的抗损伤保存的方法及保存系统
JP2024029908A (ja) * 2022-08-23 2024-03-07 株式会社Screenホールディングス 接続配管、灌流装置の準備方法、および灌流方法
USD1031028S1 (en) 2022-09-08 2024-06-11 Paragonix Technologies, Inc. Tissue suspension adaptor
CN116139350B (zh) * 2023-02-24 2023-12-12 潍坊医学院附属医院 一种泌尿外科护理用导尿装置
CN116235846B (zh) * 2023-02-27 2024-01-30 中国科学院苏州生物医学工程技术研究所 一种器官灌注控制方法、系统以及装置
CN116391705B (zh) * 2023-02-27 2023-11-24 中国科学院苏州生物医学工程技术研究所 一种用于离体器官灌流的恒温容器
US20250064674A1 (en) 2023-08-25 2025-02-27 Paragonix Technologies, Inc. Methods and systems for cyclically inflating and deflating a lung ex-vivo
US12410408B2 (en) 2024-02-02 2025-09-09 Paragonix Technologies, Inc. Method for hypothermic transport of biological samples
CN119376443A (zh) * 2024-12-27 2025-01-28 北京清瀚医疗科技有限公司 一种器官灌注设备的压力控制系统
USD1087382S1 (en) 2025-01-30 2025-08-05 Paragonix Technologies, Inc. Device for transporting a biological sample

Family Cites Families (340)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3253595A (en) 1963-08-07 1966-05-31 Cordis Corp Cardiac pacer electrode system
US3406531A (en) 1964-08-25 1968-10-22 Emil S. Swenson Apparatus for maintaining organs in a completely viable state
US3468136A (en) 1964-08-25 1969-09-23 Emil S Swenson Method for maintaining organs in a completely viable state
US3388803A (en) 1965-04-16 1968-06-18 Applied Biolog Sciences Lab In Wearable dialysis apparatus
US3545221A (en) 1967-05-22 1970-12-08 Swenko Research & Dev Inc Apparatus for maintaining organs in vitro in a completely viable state
US3537956A (en) 1967-06-26 1970-11-03 Joseph R Falcone Petrie dish
FR1577356A (da) 1968-04-04 1969-08-08
SE323475B (da) 1968-11-26 1970-05-04 Aga Ab
US3587567A (en) 1968-12-20 1971-06-28 Peter Paul Schiff Mechanical ventricular assistance assembly
US3545605A (en) 1969-01-24 1970-12-08 Ruth Robins Paint roller package
US3772153A (en) 1969-04-02 1973-11-13 Air Liquide Apparatus for the preservation of animal or human organs in living condition
US3632473A (en) 1969-04-21 1972-01-04 Univ California Method and apparatus for preserving human organs extracorporeally
BE755423A (fr) 1969-10-06 1971-02-01 Baxter Laboratories Inc Procede et appareil pour la conservation d'organes
US3660241A (en) 1970-01-12 1972-05-02 Baxter Laboratories Inc Container for organ perfusion or the like
US3639084A (en) 1970-04-06 1972-02-01 Baxter Laboratories Inc Mechanism for control pulsatile fluid flow
US3777507A (en) 1971-11-24 1973-12-11 Waters Instr Inc Renal preservation system
US3881990A (en) 1971-11-24 1975-05-06 Waters Instr Inc Method of transporting and storing organs while retaining the organs in a viable condition
US3843455A (en) 1972-09-13 1974-10-22 M Bier Apparatus and technique for preservation of isolated organs through perfusion
US3851646A (en) 1973-04-13 1974-12-03 Sarns Inc Connector for open heart surgery
US3995444A (en) 1974-11-08 1976-12-07 American Hospital Supply Corporation Organ perfusion system
US4004298A (en) 1975-03-31 1977-01-25 Sinai Hospital Of Detroit Magnetically aligned releasable connector
US4069826A (en) 1976-09-03 1978-01-24 Barlow Mfg. Corporation Surgical tube adapter clamp
US4186565A (en) 1978-05-19 1980-02-05 Henry Ford Hospital Perfusion system for organ preservation
US4231354A (en) 1978-07-14 1980-11-04 Howmedica, Incorporated Pulsatile blood pumping apparatus and method
US4186253A (en) 1978-10-10 1980-01-29 The Green Cross Corporation Perfusate for preserving organ to be transplanted and preserving method
JPS5710695A (en) 1980-04-18 1982-01-20 Cooper Edwin Inc Lubricant oil containing tertiary amine salt of sulfidized olefinic acid
JPS5710695U (da) 1980-06-17 1982-01-20
EP0054635B1 (de) 1980-12-23 1985-02-13 Dr. Franz Köhler Chemie GmbH Protektive Lösung für Herz und Niere und Verfahren zu deren Herstellung
US4801299A (en) 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
JPS60142859A (ja) 1983-12-29 1985-07-29 泉工医科工業株式会社 拍動血流量自動設定機構付ロ−ラポンプ
US4719201A (en) 1985-02-07 1988-01-12 Regents Of The University Of Minnesota Method for stimulating recovery from ischemia
US4605644A (en) 1985-02-07 1986-08-12 Regents Of The University Of Minnesota Method for stimulating recovery from ischemia employing ribose and adenine
US4666425A (en) 1985-12-17 1987-05-19 The Dis Corporation Device for perfusing an animal head
DE3614821A1 (de) 1986-05-02 1987-11-05 Siemens Ag Implantierbare, eichbare messvorrichtung fuer eine koerpersubstanz sowie eichverfahren
US4723939A (en) 1986-07-31 1988-02-09 The Research Foundation Of State Univ. Of New York Apparatus and method for multiple organ procurement
US4745759A (en) 1986-12-23 1988-05-24 Bauer Dan O Kidney preservation machine
WO1988005261A1 (en) 1987-01-16 1988-07-28 Tops Systems, Inc. Total organ perfusion system
JPS63270601A (ja) 1987-04-30 1988-11-08 Olympus Optical Co Ltd 臓器保存装置
US5051352A (en) 1987-10-07 1991-09-24 The Regents Of The University Of California Apparatus and method of preserving the viability of animal organs
US4847470A (en) 1987-12-14 1989-07-11 Bakke Allan P Electric blood warmer utilizing metallic ribbon flow cartridge and low thermal mass heating units
EP0347923A1 (en) 1988-06-23 1989-12-27 Nicholas J. Perrotta Portable pulsatile organ perfusion device and method
JPH0499701A (ja) 1988-10-26 1992-03-31 Mckelvey Karen 移植に使用するヒトの臓器の輸送用装置
EP0376763A3 (en) 1988-10-26 1992-04-01 McKelvey, Karen A device for transportation of human organs used for transplantation
US4920044A (en) 1988-11-08 1990-04-24 The Cleveland Clinic Foundation Intracellular flush solution for preserving organs
JPH02282301A (ja) 1989-04-24 1990-11-19 Olympus Optical Co Ltd 臓器保存装置
JPH02306901A (ja) 1989-05-19 1990-12-20 Olympus Optical Co Ltd 臟器保存装置
US5326706A (en) 1989-07-17 1994-07-05 Research Foundation Of State University Of New York Homeostatic organ preservation system
JPH0374302A (ja) 1989-08-15 1991-03-28 Olympus Optical Co Ltd 臓器保存装置
JPH0653160B2 (ja) 1989-08-18 1994-07-20 呉羽化学工業株式会社 拍動発生方法及び装置
US5066578A (en) 1989-12-21 1991-11-19 The Regents Of The University Of California Long-term preservation of organs for transplantation
US5358931A (en) 1990-01-17 1994-10-25 The Regents Of The University Of California Interaction of thermal hysteresis proteins with cells and cell membranes and associated applications
CA2041828A1 (en) 1990-03-05 1992-11-04 Richard L. Lindstrom Viscoelastic solution
US5145771A (en) 1990-04-12 1992-09-08 The University Of North Carolina At Chapel Hill Rinse solution for organs and tissues
JPH049301A (ja) * 1990-04-26 1992-01-14 Olympus Optical Co Ltd 臓器保存装置
JP2860301B2 (ja) 1990-09-19 1999-02-24 ヘキスト・マリオン・ルセル株式会社 臓器保存用溶液
FR2667297B1 (fr) 1990-09-28 1994-05-27 Electrolux Sarl Conteneur medical climatise.
US5395314A (en) 1990-10-10 1995-03-07 Life Resuscitation Technologies, Inc. Brain resuscitation and organ preservation device and method for performing the same
US5584804A (en) 1990-10-10 1996-12-17 Life Resuscitation Technologies, Inc. Brain resuscitation and organ preservation device and method for performing the same
US5498427A (en) 1990-11-20 1996-03-12 Pasteur Merieux Serums Et Vaccines Solutions for the perfusion, preservation and reperfusion of organs
DE4204477B4 (de) 1991-02-15 2005-06-30 Cobe Cardiovascular Inc., Arvada Medizinische Einrichtung, damit zu verbindende Sonde und Kontrollbox hierfür
US6090776A (en) 1991-03-11 2000-07-18 Creative Bio Molecules, Inc. Morphogen treatment of organ implants
US5381510A (en) 1991-03-15 1995-01-10 In-Touch Products Co. In-line fluid heating apparatus with gradation of heat energy from inlet to outlet
US5157930A (en) 1991-04-22 1992-10-27 Mcghee Samuel C Organ preservation apparatus
US5856081A (en) 1991-07-08 1999-01-05 The American National Red Cross Computer controlled cryoprotectant perfusion apparatus
US5217860A (en) 1991-07-08 1993-06-08 The American National Red Cross Method for preserving organs for transplantation by vitrification
US5200398A (en) 1991-09-12 1993-04-06 Mount Sinai Hospital Corporation Composition for the preservation of organs comprising glucuronic acid or a physiologically tolerated salt or ester thereof
US5407793A (en) 1991-10-18 1995-04-18 University Of Pittsburgh Of The Commonwealth System Of Higher Education An aqueous heart preservation and cardioplegia solution
DE4201259C2 (de) 1992-01-18 1994-12-08 Sachs Elektronik Kg Hugo Vorrichtung zur Perfusion der Koronargefäße eines isolierten Herzens
US5654266A (en) 1992-02-10 1997-08-05 Chen; Chung-Ho Composition for tissues to sustain viability and biological functions in surgery and storage
US5552267A (en) 1992-04-03 1996-09-03 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5370989A (en) 1992-04-03 1994-12-06 The Trustees Of Columbia University In The City Of New York Solution for prolonged organ preservation
US5306711A (en) 1992-06-24 1994-04-26 Georgetown University Organ preservative solution
JPH0656601A (ja) 1992-08-07 1994-03-01 Morishita Roussel Kk 移植臓器用の電解質溶液
US5338662A (en) 1992-09-21 1994-08-16 Bio-Preserve Medical Corporation Organ perfusion device
US5354268A (en) 1992-11-04 1994-10-11 Medical Instrument Development Laboratories, Inc. Methods and apparatus for control of vacuum and pressure for surgical procedures
US5362622A (en) 1993-03-11 1994-11-08 Board Of Regents, The University Of Texas System Combined perfusion and oxygenation apparatus
US5599659A (en) 1993-03-11 1997-02-04 Breonics, Inc. Preservation solution for ex vivo, warm preservation of tissues, explants,organs and vascular endothelial cells comprising retinal-derived fibroblast growth factor, cyclodextrin and chondroitin sulfate
US5356771A (en) 1993-03-11 1994-10-18 Board Of Regents, The University Of Texas System Combined perfusion and oxygenation organ preservation apparatus
AU6409594A (en) 1993-03-16 1994-10-11 Alliance Pharmaceutical Corporation Preservation solution and method for warm organ preservation
JPH06305901A (ja) 1993-04-26 1994-11-01 Akio Kawamura 室温下保存用灌流液およびこれを用いた保存方法
US5385540A (en) 1993-05-26 1995-01-31 Quest Medical, Inc. Cardioplegia delivery system
US6680305B1 (en) 1993-06-04 2004-01-20 Biotime, Inc. Physiologically acceptable aqueous solutions and methods for their use
WO1994028950A1 (en) 1993-06-04 1994-12-22 Biotime, Inc. Plasma-like solution
DE9422008U1 (de) 1993-06-07 1997-08-28 Mayer, Berndt, Priv.-Doz. Dr.med., 10585 Berlin Vorrichtung zur Konservierung von Organen, Extremitäten und Gewebelappen
US5405742A (en) 1993-07-16 1995-04-11 Cyromedical Sciences, Inc. Solutions for tissue preservation and bloodless surgery and methods using same
AU7560994A (en) * 1993-08-12 1995-03-14 University Of North Carolina At Chapel Hill, The Rinse solution for organs and tissues
EP2113196A3 (en) 1993-11-05 2009-12-23 ResMed Limited Control of CPAP treatment
DE4342728A1 (de) * 1993-12-15 1995-06-22 Thomae Gmbh Dr K Verfahren, Apparate und Perfusionslösungen zur Konservierung explantierter Organe
US5511958A (en) 1994-02-10 1996-04-30 Baxter International, Inc. Blood pump system
US5643712A (en) 1994-05-20 1997-07-01 Brasile; Lauren Method for treating and rendering grafts nonthrombogenic and substantially nonimmunogenic using an extracellular matrix coating
AU2595195A (en) 1994-05-20 1995-12-18 Vec Tec, Inc. Method and apparatus monitoring viability of transplantable organs
US6375613B1 (en) 1994-05-20 2002-04-23 Breonics, Inc. Prognostic testing of organs intended for transplantation
US5505709A (en) 1994-09-15 1996-04-09 Minimed, Inc., A Delaware Corporation Mated infusion pump and syringe
US5473791A (en) 1994-09-22 1995-12-12 Holcomb; Tim C. Paint roller and tray apparatus
JPH0889518A (ja) 1994-09-25 1996-04-09 Terumo Corp 中空器官接続用器具
US5554123A (en) 1994-10-31 1996-09-10 Glenn Herskowitz Portable infusion pump
US5554497A (en) 1994-12-12 1996-09-10 Charlotte-Mecklenburg Hospital Authority Cardioplegic solution for arresting an organ
AU4420396A (en) 1994-12-12 1996-07-03 Charlotte-Mecklenburg Hospital Authority Organ transplant solutions and method for transplanting an organ
CA2208485A1 (en) 1994-12-22 1996-06-27 Ravichandran Ramasamy Method for protecting the heart from ischemia
US5882328A (en) 1995-01-13 1999-03-16 Qlt Phototherapeutics, Inc. Method to prevent transplant rejection
US5656420A (en) 1995-02-24 1997-08-12 University Of Kentucky Research Foundation Method for employing the delta opioid dadle to extend tissue survival time during ischemia
WO1996029865A1 (en) 1995-03-27 1996-10-03 Organ, Inc. Organ evaluation and resuscitation device and method
US5586438A (en) 1995-03-27 1996-12-24 Organ, Inc. Portable device for preserving organs by static storage or perfusion
GB9506312D0 (en) 1995-03-28 1995-05-17 Medical Res Council Improvements in or relating to sample processing
US5679565A (en) 1995-04-10 1997-10-21 The Regents Of The University Of California Method of preserving pancreatic islets
JP3845736B2 (ja) 1995-09-18 2006-11-15 レスメッド・リミテッド Cpap治療又は補助された人工呼吸における圧力制御
DE19535781C2 (de) 1995-09-26 1999-11-11 Fraunhofer Ges Forschung Vorrichtung zur aktiven Strömungsunterstützung von Körperflüssigkeiten
US5759148A (en) 1995-10-18 1998-06-02 Sipin; Anatole J. Controlled pneumatic driving system
US5770149A (en) 1995-10-31 1998-06-23 Baxter International Extracorporeal blood oxygenation system having integrated blood pump, heat exchanger and membrane oxygenator
US6794124B2 (en) 1995-12-15 2004-09-21 Stiftelsen Facthor Preservation solution
SE505499C2 (sv) 1995-12-15 1997-09-08 Stiftelsen Facthor Förvaringslösning för organ och vävnad eller delar därav från människor och djur innehållande kalcium och nitroglycerin, användning därav samt förfarande för förvaring därmed
US5843024A (en) 1996-05-17 1998-12-01 Breonics, Inc. Solution and process for resuscitation and preparation of ischemically damaged tissue
US5965433A (en) 1996-05-29 1999-10-12 Trans D.A.T.A. Service, Inc. Portable perfusion/oxygenation module having mechanically linked dual pumps and mechanically actuated flow control for pulsatile cycling of oxygenated perfusate
US5716378A (en) 1996-06-06 1998-02-10 Medtronic, Inc. Heart preservation and transportation apparatus and method employing low rate cardiac pacing for improved removal of catabolites from the myocardium
SG48362A1 (en) 1996-06-25 1998-04-17 Thomas & Betts Corp Single-sided straddle mount printed circuit board connector
US5801442A (en) 1996-07-22 1998-09-01 Northrop Grumman Corporation Microchannel cooling of high power semiconductor devices
US5807737A (en) 1996-07-26 1998-09-15 Schill Enterprises, Inc. Heart and lung support assembly
US6783328B2 (en) 1996-09-30 2004-08-31 Terumo Cardiovascular Systems Corporation Method and apparatus for controlling fluid pumps
US5776063A (en) 1996-09-30 1998-07-07 Molecular Biosystems, Inc. Analysis of ultrasound images in the presence of contrast agent
US5787544A (en) 1996-12-20 1998-08-04 Ppg Industries, Inc. Combined paint package and roller tray
US6642045B1 (en) 1997-04-14 2003-11-04 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US6217546B1 (en) 1997-05-19 2001-04-17 United States Surgical Corporation Catheter system
EP0991373B1 (de) 1997-06-21 2004-09-15 Acorn Cardiovascular, Inc. Beutel zur wenigstens teilweisen umfassung eines herzens
US6123725A (en) 1997-07-11 2000-09-26 A-Med Systems, Inc. Single port cardiac support apparatus
US20050027237A1 (en) 1997-09-03 2005-02-03 Dan Weiner Apparatus and methods for control of intravenous fluids
JP2001516768A (ja) 1997-09-23 2001-10-02 ハッサネイン,ワリード,エイチ. 臓器を維持するための組成物、方法及び装置
US8409846B2 (en) * 1997-09-23 2013-04-02 The United States Of America As Represented By The Department Of Veteran Affairs Compositions, methods and devices for maintaining an organ
US6100082A (en) 1997-09-23 2000-08-08 Hassanein; Waleed H. Perfusion apparatus and method including chemical compositions for maintaining an organ
US6953655B1 (en) 1997-09-23 2005-10-11 The United States Of America As Represented By The Department Of Veterans Affairs Compositions, methods and devices for maintaining an organ
US6110139A (en) 1997-10-21 2000-08-29 Loubser; Paul Gerhard Retrograde perfusion monitoring and control system
US6352543B1 (en) 2000-04-29 2002-03-05 Ventrica, Inc. Methods for forming anastomoses using magnetic force
ES2179443T3 (es) 1998-04-21 2003-01-16 Guala Dispensing Spa Bomba con diafragma con forma de copa para dispensadores de gatillo.
GR1003087B (el) 1998-06-30 1999-03-08 Αυτοκαθαριζομενη υδραυλικη τουαλετα για γατες που δεν χρησιμοποιει αμμο υγειας
US6613785B2 (en) 1998-07-21 2003-09-02 Smithkline Beecham Plc Use of glucose uptake enhancer for reducing post-ischemic injury of the heart
US6042550A (en) 1998-09-09 2000-03-28 Ntc Technology, Inc. Methods of non-invasively estimating intrapulmonary shunt fraction and measuring cardiac output
US6050987A (en) 1998-09-21 2000-04-18 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Tubular coupling
US7749693B2 (en) 1998-09-29 2010-07-06 Lifeline Scientific, Inc. Method of determining that an organ is not suitable for transplantation and using it for testing substances
EP1929863B1 (en) 1998-09-29 2016-11-09 Organ Recovery Systems, Inc. Apparatus and method for maintaining and/or restoring viability of organs
US6977140B1 (en) 1998-09-29 2005-12-20 Organ Recovery Systems, Inc. Method for maintaining and/or restoring viability of organs
US6673594B1 (en) 1998-09-29 2004-01-06 Organ Recovery Systems Apparatus and method for maintaining and/or restoring viability of organs
DE69922985T2 (de) 1998-10-22 2005-12-15 Medtronic, Inc., Minneapolis Verfahren zur untersuchung an einem isolierten perfundierten herz-präparat
US7045279B1 (en) 1998-10-22 2006-05-16 Medtronic, Inc. Isolated perfused heart preparation and method of use
US6587734B2 (en) 1998-11-04 2003-07-01 Acorn Cardiovascular, Inc. Cardio therapeutic heart sack
US6144444A (en) 1998-11-06 2000-11-07 Medtronic Avecor Cardiovascular, Inc. Apparatus and method to determine blood parameters
FR2785501B1 (fr) 1998-11-10 2001-01-05 Centre Nat Rech Scient Solution de perfusion et/ou de conservation et/ou de reperfusion lors de la transplantation d'organes
US6128519A (en) 1998-12-16 2000-10-03 Pepex Biomedical, Llc System and method for measuring a bioanalyte such as lactate
US6168877B1 (en) 1998-12-18 2001-01-02 Aer Energy Resources, Inc. Air-managing system for metal-air battery using resealable septum
DK1152690T3 (da) 1999-02-03 2008-10-27 Mermaid Care As Automatisk bestemmelse af repiratoriske parametre
US6589223B1 (en) 1999-02-03 2003-07-08 Biotime, Inc. Method and compositions for use in perfusion applications
WO2000051659A1 (en) 1999-03-05 2000-09-08 Matson Louis R Surface-modified bioactive surgical implants suppressing tissue growth
SE9901056D0 (sv) 1999-03-23 1999-03-23 Pacesetter Ab Sensor system
GB9907372D0 (en) 1999-03-30 1999-05-26 Concentric Pumps Ltd Improvements in pumps
GB9908335D0 (en) 1999-04-12 1999-06-09 Univ Cambridge Tech Methods and means for extracorporeal organ perfusion
US6194137B1 (en) 1999-04-13 2001-02-27 Organ Recovery Systems, Inc. Method of cryopreservation of blood vessels by vitrification
US6582953B2 (en) 1999-04-14 2003-06-24 Breonics, Inc. Organ chamber for exsanguinous metabolic support system
US20040038192A1 (en) 1999-04-14 2004-02-26 Breonics, Inc. System for exsanguinous metabolic support of an organ or tissue
US6365338B1 (en) 1999-04-27 2002-04-02 David A. Bull Organ preservative solution containing trehalose, anti-oxidant, cations and an energy source
US6567679B1 (en) 1999-05-28 2003-05-20 E-Monitors, Inc. Method of using a pH tissue monitor
US20030040665A1 (en) 1999-05-28 2003-02-27 E-Monitors, Inc. Systems and methods of pH tissue monitoring
JP5230042B2 (ja) 1999-06-02 2013-07-10 株式会社ビーエムジー 動物の細胞または臓器の保存剤およびその保存方法。
WO2001001774A1 (en) 1999-06-17 2001-01-11 Regents Of The University Of California Continuous cardiac perfusion preservation with peg-hb for improved hypothermic storage
DE19928485C1 (de) 1999-06-22 2000-10-19 Jostra Medizintechnik Ag Perfusionssystem für menschliche oder tierische Organe oder Körperteile
JP4331869B2 (ja) 1999-06-24 2009-09-16 株式会社根本杏林堂 心拍動下冠動脈バイパス手術用自己血潅流装置
CA2286929A1 (en) 1999-10-18 2001-04-18 Anthony Paolitto Valve surgery apparatus
CN2418882Y (zh) 1999-10-20 2001-02-14 张国报 离体肺循环灌流新装置
US6764462B2 (en) 2000-11-29 2004-07-20 Hill-Rom Services Inc. Wound treatment apparatus
US6375611B1 (en) 2000-01-07 2002-04-23 Origin Medsystems, Inc. Organ stabilizer
US6492103B1 (en) 2000-01-31 2002-12-10 Organ Recovery Systems, Inc. System for organ and tissue preservation and hypothermic blood substitution
AU2001241540A1 (en) * 2000-02-17 2001-08-27 Johns Hopkins University Transplant organ external cooling system
WO2001065935A1 (en) 2000-03-08 2001-09-13 Yoram Vodovotz Kidney perfusion solution containing nitric oxide donor
US6794182B2 (en) 2000-03-13 2004-09-21 E. George Wolf, Jr. Hyperbaric oxygen organ preservation system (HOOPS)
US6569615B1 (en) 2000-04-10 2003-05-27 The United States Of America As Represented By The Department Of Veteran's Affairs Composition and methods for tissue preservation
US7611830B2 (en) 2000-04-10 2009-11-03 The United States Of America As Represented By The Department Of Veteran's Affairs Device to lavage a blood vessel
US6389308B1 (en) 2000-05-30 2002-05-14 Vladimir Shusterman System and device for multi-scale analysis and representation of electrocardiographic data
US6492745B1 (en) 2000-07-17 2002-12-10 Marconi Communications, Inc. Battery disconnect system
CA2417331C (en) 2000-07-28 2011-03-22 Christopher J. Murphy Transplant media comprising bnp-1
US20030135152A1 (en) 2000-09-27 2003-07-17 Kollar Kevin J. Disposable cartridge for a blood perfusion system
JP2002119586A (ja) 2000-10-16 2002-04-23 Univ Nihon 血液温冷ないし体温調整方法およびその装置
US6490880B1 (en) 2000-10-26 2002-12-10 Islet Technology Inc. Regulated organ containment shipping system using dual-layer preservation liquid
AU1444302A (en) 2000-11-03 2002-05-15 Vitrolife Ab Evaluation and preservation solution
US6602718B1 (en) 2000-11-08 2003-08-05 Becton, Dickinson And Company Method and device for collecting and stabilizing a biological sample
US20040236170A1 (en) 2000-11-15 2004-11-25 Ducksoo Kim Method for surgically joining a ventricular assist device to the cardiovascular system of a living subject using a piercing introducer assembly
EP1356169B1 (en) 2000-12-21 2006-06-14 Dresser-Rand Company Double layer acoustic liner and fluid pressurizing device
US20020132220A1 (en) 2000-12-27 2002-09-19 Berens Kurt L. Use of selectin antagonists in organ preservation solutions
US6643546B2 (en) 2001-02-13 2003-11-04 Quetzal Biomedical, Inc. Multi-electrode apparatus and method for treatment of congestive heart failure
US6475716B1 (en) 2001-03-06 2002-11-05 Biobank Co., Ltd. Method for preserving mammalian organs
EP1372916A2 (en) 2001-03-21 2004-01-02 Vitrox APS Method and housing for performing operations on a material
US20020187132A1 (en) 2001-04-30 2002-12-12 Mcgregor Christopher G.A. Cardiac gene transfer
DE10121159B4 (de) 2001-04-30 2004-01-29 Biederer, Jürgen, Dr. med. Künstlicher Thorax
WO2002089571A1 (en) 2001-05-04 2002-11-14 Breonics, Inc. Organ chamber for exsanguinous metabolic support system
US6894690B2 (en) 2001-06-20 2005-05-17 Engineering Technology Associates, Inc. Method and apparatus for capturing and viewing a sequence of 3-D images
US6631830B2 (en) 2001-08-20 2003-10-14 Larami Limited Snap action ball valve assembly and liquid dispenser using same
US6677150B2 (en) 2001-09-14 2004-01-13 Organ Transport Systems, Inc. Organ preservation apparatus and methods
US6924267B2 (en) 2001-09-18 2005-08-02 Suomen Punainen Risti Veripalvelu Methods and active substances for protecting organs
EP1439750A4 (en) 2001-09-28 2004-10-27 Harry F Hull SIMPLE, FULLY TRANSPORTABLE DEVICE FOR MAINTAINING AN EXCLUSIVE HEART IN OPTIMAL CONDITION FOR TRANSPLANTATION PURPOSES
US6609987B1 (en) 2001-10-01 2003-08-26 General Motors Corporation Hydraulic timing chain tensioner assembly
FR2830183B1 (fr) 2001-10-02 2004-06-11 Daniel Roux Prothese aortique avec dispositif rapide de connexion a la circulation extra-corporelle
US6582375B2 (en) 2001-10-11 2003-06-24 University Of Cincinnati System for study of global uni-or bi-ventricular function of an explanted, reperfused heart
EP1450952B1 (en) 2001-10-12 2016-09-21 Becton, Dickinson and Company Apparatus for storing biological samples
US20030074760A1 (en) 2001-10-19 2003-04-24 Rdk Company Paint applicator system
US6910483B2 (en) 2001-12-10 2005-06-28 Resmed Limited Double-ended blower and volutes therefor
SG108829A1 (en) 2001-12-14 2005-02-28 Agilent Technologies Inc Photo-receiver arrangement
EP1321159A1 (en) 2001-12-21 2003-06-25 CHIESI FARMACEUTICI S.p.A. Pressurized metered dose inhaler (pMDI) actuators with laser drilled orifices
JP2003206201A (ja) * 2001-12-28 2003-07-22 Katsutoshi Naruse 臓器収納装置を含む移植用臓器保存装置および該収納装置を含む人工臓器システム
US20030124503A1 (en) 2001-12-28 2003-07-03 Olivencia-Yurvati Albert H. Pyruvate cardioplegia solutions for administration to the heart during cardiopulmonary surgery and methods of use thereof
US6847682B2 (en) 2002-02-01 2005-01-25 Hughes Electronics Corporation Method, system, device and computer program product for MPEG variable bit rate (VBR) video traffic classification using a nearest neighbor classifier
US6878339B2 (en) 2002-02-19 2005-04-12 Horiba, Ltd. NOx-concentration measuring apparatus
JP2003315220A (ja) 2002-02-19 2003-11-06 Horiba Ltd 窒素酸化物測定装置
JP4485208B2 (ja) 2002-02-21 2010-06-16 デザイン・メンター・インコーポレイテッド 流体ポンプ
AUPS214502A0 (en) 2002-05-06 2002-06-06 Uscom Pty Ltd Blood flow oxygen measurement
AUPS312602A0 (en) 2002-06-21 2002-07-18 James Cook University Organ arrest, protection, preservation and recovery
TW527101U (en) 2002-07-23 2003-04-01 Abit Comp Corp Interface card heat sink
US7572622B2 (en) 2002-08-14 2009-08-11 Transmedic, Inc. Heart preservation chamber
US6875605B1 (en) 2002-08-21 2005-04-05 Florida State University Research Foundation, Inc. Modular cell culture bioreactor and associated methods
AU2003262836A1 (en) 2002-08-23 2004-03-11 Organ Recovery Systems Connectors, particularity for transplant organs
US20040170950A1 (en) 2002-09-12 2004-09-02 Prien Samuel D. Organ preservation apparatus and methods
WO2004026031A2 (en) 2002-09-18 2004-04-01 Lifeblood Medical Inc. Organ preservation and transportation apparatus and method
US20060166360A1 (en) 2002-10-18 2006-07-27 The General Hospital Corporation Compositions, solutions, and methods used for transplantation
WO2004056180A1 (en) 2002-12-23 2004-07-08 Global Cardiac Solutions Pty Ltd Organ preconditioning, arrest, protection, preservation and recovery (1)
US7198751B2 (en) 2003-01-14 2007-04-03 Medtronic, Inc. Disposable, integrated, extracorporeal blood circuit
US20040193096A1 (en) 2003-03-25 2004-09-30 Cooper William Isaac Conceptus chamber
US20050085762A1 (en) 2003-03-31 2005-04-21 Venkataramana Vijay Perfusion circuit for cardiopulmonary bypass with air removal system
EP1613153B1 (en) 2003-04-04 2021-06-02 Organ Recovery Systems, Inc. Methods and apparatus for perfusion, diagnosis, storage and/or transport of an organ or tissue
WO2004089085A2 (en) 2003-04-04 2004-10-21 Organ Recovery Systems, Inc. Device for separating gas from a liquid path
JP2004307404A (ja) 2003-04-08 2004-11-04 Nipro Corp 人工酸素運搬体を含む医薬組成物
US20040202993A1 (en) 2003-04-10 2004-10-14 Poo Ramon E. Apparatus and method for organ preservation and transportation
CA2522941A1 (en) 2003-04-23 2004-11-04 Human Biosystems Improved methods and solutions for storing donor organs
EP1475434A1 (en) 2003-05-09 2004-11-10 Oncoscience AG Method for storing tumor cells
CN1233231C (zh) 2003-05-12 2005-12-28 四川大学华西医院 持续灌注心脏保存装置
CN2616058Y (zh) 2003-05-12 2004-05-19 四川大学华西医院 持续灌注心脏保存装置
KR20060112705A (ko) 2003-07-08 2006-11-01 벤터 테크놀로지 리미티드 대동맥 협착증의 치료에서 동맥 경유 송달용 이식가능한인공 기구 및 이러한 기구의 이식방법
WO2005004950A1 (ja) 2003-07-10 2005-01-20 Nikkiso Co., Ltd. 脈拍数測定方法、血圧測定方法、及び血管アクセス監視方法、並びにそれらを用いた医療装置
NL1024022C2 (nl) 2003-07-30 2005-02-01 Technologiestichting Stw Draagbare preservatie-inrichting voor een donororgaan.
DE10340487B4 (de) 2003-09-03 2007-07-12 Technische Universität Dresden Perfusionskreislauf
US20050170019A1 (en) 2003-10-22 2005-08-04 Fred Hutchinson Cancer Research Center Methods, compositions and devices for inducing stasis in cells
BRPI0306282B8 (pt) 2003-12-26 2021-06-22 Intermed Equipamento Medico Hospitalar Ltda sistema de ventilação em aparelho respiratório
US20050153271A1 (en) 2004-01-13 2005-07-14 Wenrich Marshall S. Organ preservation apparatus and methods
JP3742894B2 (ja) * 2004-01-14 2006-02-08 ダイキン工業株式会社 温度制御装置
WO2005074657A2 (en) 2004-02-02 2005-08-18 The General Hospital Corporation Modified organ support devices
US7316666B1 (en) 2004-04-12 2008-01-08 Arizant Healthcare Inc. Fluid warming cassette with rails and a stiffening member
US7390028B2 (en) 2004-05-12 2008-06-24 Blazek Larry M Medical tubing quick disconnect apparatus
US8741555B2 (en) 2004-05-14 2014-06-03 Organ Recovery Systems, Inc. Apparatus and method for perfusion and determining the viability of an organ
JP2007295802A (ja) * 2004-07-23 2007-11-15 Mebix Kk 微生物及び動物由来物の保存方法
US20060039870A1 (en) 2004-08-20 2006-02-23 Turner Jeffrey D Pulmonary delivery of enzymatic medical countermeasures
DE102004048991B4 (de) 2004-10-04 2010-01-28 Biotronik Crm Patent Ag Elektrodenleitung
US8304181B2 (en) 2004-10-07 2012-11-06 Transmedics, Inc. Method for ex-vivo organ care and for using lactate as an indication of donor organ status
AU2016222388B2 (en) 2004-10-07 2017-12-07 Transmedics, Inc. Systems and methods for ex-vivo organ care
US7651835B2 (en) 2004-10-07 2010-01-26 Transmedics, Inc. Method of timing pulsatile flow of normothermic perfusate to the heart
US9301519B2 (en) 2004-10-07 2016-04-05 Transmedics, Inc. Systems and methods for ex-vivo organ care
US12010987B2 (en) 2004-10-07 2024-06-18 Transmedics, Inc. Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status
WO2006060309A2 (en) 2004-11-24 2006-06-08 The Trustees Of Columbia University In The City Of New York Compositions and methods for ex vivo preservations of organs
US20060134073A1 (en) 2004-11-24 2006-06-22 Yoshifumi Naka Compositions and methods for ex vivo preservation of blood vessels for vascular grafts using analogues of cAMP and cGMP
US20090182302A1 (en) 2004-11-30 2009-07-16 Anthony Garabet Method and apparatus for pressurizing a body cavity for diagnostic and rehabilitative purposes
CA2592407A1 (en) 2004-12-24 2006-06-29 The University Of Queensland Methods of treating pain
US20060160062A1 (en) 2005-01-14 2006-07-20 Young Lindon H Perfusion and/or preservation solution for organs
US20060182722A1 (en) 2005-02-11 2006-08-17 Hering Bernhard J Methods and materials for isolating isogenic islet cells
US7452711B2 (en) 2005-05-09 2008-11-18 Victor Daykin Contact plate
CN101171332A (zh) 2005-05-12 2008-04-30 佛罗里达大学研究基金公司 用于调节血流的物质和方法
US9078428B2 (en) 2005-06-28 2015-07-14 Transmedics, Inc. Systems, methods, compositions and solutions for perfusing an organ
DE102005048625A1 (de) 2005-10-11 2007-04-12 Universität Leipzig System zur nicht-kardioplegischen Konservierung von Spenderherzen für die Transplantation
US7575856B2 (en) 2005-10-28 2009-08-18 The United States Of America As Represented By The Department Of Veterans Affairs Compositions and methods for the evaluation and resuscitation of cadaveric hearts for transplant
KR20140014318A (ko) 2005-11-17 2014-02-05 니뽄젠야쿠코교 가부시키가이샤 세포 보존용 수용액
CA2896083A1 (en) 2005-12-08 2007-06-14 Insmed Incorporated Lipid-based compositions of antiinfectives for treating pulmonary infections and methods of use thereof
US20070135760A1 (en) 2005-12-14 2007-06-14 Williams David L Occlusion clearance in microsurgical system
US7559914B2 (en) 2005-12-14 2009-07-14 Alcon, Inc. Priming a microsurgical system
KR20080097190A (ko) 2005-12-29 2008-11-04 안트로제네시스 코포레이션 태반 줄기세포의 수집과 보존을 위한 개선된 조성물과 이조성물의 이용 방법
CA2636715A1 (en) * 2006-01-13 2007-07-19 Smm Medical Ab Device, system and method for compression treatment of a body part
ES2625850T3 (es) 2006-04-19 2017-07-20 Transmedics, Inc. Procedimientos para el cuidado de órganos ex vivo
ES2761938T3 (es) 2006-05-22 2020-05-21 Biovest Int Inc Método y sistema para la producción de células
WO2008008781A2 (en) 2006-07-10 2008-01-17 Hollister Incorporated Vacuum control system for a breast pump
BRPI0807918A2 (pt) 2007-02-17 2017-05-16 Harvard College composições e método para preservação de tecido
US8986978B2 (en) 2007-03-01 2015-03-24 Lifeline Scientific, Inc. Perfusion regulation
WO2008106724A1 (en) 2007-03-02 2008-09-12 Hibernation Therapeutics Limited Transplants
US9457179B2 (en) 2007-03-20 2016-10-04 Transmedics, Inc. Systems for monitoring and applying electrical currents in an organ perfusion system
US20080286746A1 (en) 2007-05-17 2008-11-20 Biorep Technologies, Inc. Perfusion apparatus and method
US20080295839A1 (en) 2007-06-01 2008-12-04 Habashi Nader M Ventilator Apparatus and System of Ventilation
ES2493641T3 (es) 2007-06-28 2014-09-12 Cydex Pharmaceuticals, Inc. Administración nasal de soluciones acuosas de corticosteroides
NZ585622A (en) 2007-12-17 2012-10-26 Medical Res Council Technology Hepatitis c virus antibodies
US10750738B2 (en) 2008-01-31 2020-08-25 Transmedics, Inc. Systems and methods for ex vivo lung care
ES2328660B1 (es) * 2008-05-14 2010-10-14 Fundacio Privada Clinic Per A La Recerca Biomedica Dispositivo para la preservacion de un injerto hepatico en condiciones de normotermia.
WO2010036726A1 (en) 2008-09-23 2010-04-01 Cedars-Sinai Medical Center Methods and apparatus for perfusion of an explanted donor heart
US9113624B2 (en) * 2008-10-15 2015-08-25 Covidien Lp System and method for perfusing biological organs
WO2010091188A1 (en) 2009-02-04 2010-08-12 Yale University Tissue engineering of lung
US8167869B2 (en) 2009-02-10 2012-05-01 Tyco Healthcare Group Lp Wound therapy system with proportional valve mechanism
GB0903299D0 (en) 2009-02-26 2009-04-08 Guys And St Thomas Nhs Foundat Composition and methods
US10370245B2 (en) 2009-06-22 2019-08-06 Sanford-Burnham Medical Research Institute Methods and compositions using peptides and proteins with C-terminal elements
US8337783B2 (en) 2009-06-23 2012-12-25 The United States of America as represented by the Secretary of Commerce, the National Institute of Standards and Technology Magnetic connectors for microfluidic applications
WO2011002926A2 (en) 2009-07-01 2011-01-06 The General Hospital Corporation Isolated adult cells, artificial organs,rehabilitated organs, research rools, organ encasements, organ perfusion systems, and methods for preparing and utilizing the same
JP5574147B2 (ja) * 2009-08-25 2014-08-20 国立大学法人広島大学 血液粘度の推定方法、血液粘度比の推定方法、血液粘度モニタリング装置、及び、血液粘度比モニタリング装置
SE534527C2 (sv) 2009-09-24 2011-09-20 Vivoline Medical Ab Förfarande, anordning och vätska för behandling av ett hjärta efter uttagning
US9320269B2 (en) 2009-09-25 2016-04-26 John Brassil Organ preservation system
US8685709B2 (en) * 2009-09-25 2014-04-01 Board Of Regents Of The University Of Texas System Fluidics based pulsatile perfusion preservation device and method
DK2848256T3 (da) 2009-12-08 2019-03-04 Univ Vanderbilt Forbedrede fremgangsmåder og sammensætninger til venehøst og autotransplantation
US20110294108A1 (en) 2010-05-28 2011-12-01 Tyco Healthcare Group Lp System and Method for an Ex Vivo Body Organ Electrosurgical Research Device
CN102971036B (zh) 2010-07-02 2016-04-20 皇家飞利浦电子股份有限公司 用于执行呼吸诊断的系统
US8715305B2 (en) 2010-09-03 2014-05-06 The Board Of Regents Of The University Of Texas Systems Magnetic ventricular connector
SE535502C2 (sv) * 2010-09-14 2012-08-28 Calmark Sweden Ab System och metod för att analysera risk eller förekomst av organsvikt
PT2621569T (pt) 2010-09-28 2017-07-14 B&D Electromedical Ltd Dispositivo de tratamento
CN103442675B (zh) 2011-03-23 2016-04-06 维沃琳医药有限公司 用于将获取的器官维持能存活且可运输的装置
NZ616699A (en) 2011-04-14 2016-03-31 Transmedics Inc Organ care solution for ex-vivo machine perfusion of donor lungs
US9642625B2 (en) 2011-04-29 2017-05-09 Lifeline Scientific, Inc. Cannula for a donor organ with or without an aortic cuff or patch
FR2975869B1 (fr) 2011-05-31 2017-03-03 Hemarina Composition de preservation d'organe et utilisations
CA2774383A1 (en) 2011-06-22 2012-12-22 Shaf Keshavjee Repaired organ and method for making the same
EP2750499B1 (en) 2011-09-02 2016-07-20 Organ Assist B.V. Apparatus, system and method for conditioning and preserving an organ from a donor
EP2775828B1 (en) 2011-11-10 2018-05-30 Organox Limited Organ perfusion system
GB201119420D0 (en) 2011-11-10 2011-12-21 Organox Ltd Oxygen supply for organ perfusion systems
EP2775829B1 (en) 2011-11-10 2018-07-11 Organox Limited Organ perfusion systems
CN103930138B (zh) 2011-11-23 2016-06-22 凯希特许有限公司 用于同时处理多个组织部位的减压系统、方法和装置
WO2013106908A1 (en) 2012-01-17 2013-07-25 University Of Manitoba Apparatus for testing, assessment, and maintenance of harvested hearts for transplanting
US20140315175A1 (en) 2012-01-24 2014-10-23 Pulmonx Corporation System for simulating lung function
EP2864687B1 (en) 2012-06-21 2017-06-14 Fiskars Oyj Abp Quick connect and quick disconnect system and method of manipulating a quick connect and quick disconnect system
US9402389B2 (en) * 2012-07-10 2016-08-02 Lifeline Scientific, Inc. Organ transport apparatus with sample compartments
US8814889B2 (en) 2012-07-10 2014-08-26 Lifeline Scientific, Inc. Cannula with floating clamp member
US10602740B2 (en) * 2012-07-10 2020-03-31 Lifeline Scientific, Inc. Organ perfusion apparatus with downstream flow control
US9565853B2 (en) 2012-07-10 2017-02-14 Lifeline Scientific, Inc. Perfusion apparatus with reduced pressure fluctuations, and bubble trap
GB201216928D0 (en) 2012-09-21 2012-11-07 I2R Medical Ltd Portable medical device system
WO2014059316A1 (en) * 2012-10-12 2014-04-17 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Compositions and methods for organ preservation
US9629977B2 (en) 2012-11-09 2017-04-25 Carefusion 303, Inc. Capping device for a medical access connector
US9629358B2 (en) 2013-03-15 2017-04-25 Mallinckrodt Hospital Products IP Limited Administration and monitoring of nitric oxide in ex vivo fluids
WO2014144184A2 (en) 2013-03-15 2014-09-18 Ino Therapeutics Llc Therapeutic gas delivery device with pulsed and continuous flow control
EP3003025B1 (en) 2013-06-07 2020-04-08 Perfusion Solutions Pty Ltd Device for use in evaluation, transportation or storage of a donor heart
SE538477C2 (sv) 2013-10-24 2016-07-19 Vivoline Medical Ab Anordning för undersökning av ett isolerat slående hjärta
CN203724222U (zh) 2014-01-20 2014-07-23 辽宁中医药大学 大动物离体工作心双通道灌流实验设备
WO2015126853A1 (en) 2014-02-18 2015-08-27 Baylor College Of Medicine Negative pressure ex vivo lung ventilation and perfusion system
US20160361476A1 (en) * 2014-02-28 2016-12-15 Bdbc Sciences Corp. System for tissue manipulation
US10918102B2 (en) 2014-03-13 2021-02-16 The General Hospital Corporation Devices and methods to improve and assess viability of human livers
CA2942714C (en) 2014-03-14 2023-09-05 The General Hospital Corporation Lung bioreactor
WO2015143552A1 (en) 2014-03-26 2015-10-01 University Of Manitoba Apparatus for maintenance of harvested hearts for transplanting
JP6580329B2 (ja) 2014-03-31 2019-09-25 シスメックス株式会社 未分化細胞から分化細胞および/または分化細胞の産生物を取得する方法
US10433539B2 (en) 2014-04-10 2019-10-08 Tevosol, Inc. Composition and solution with controlled calcium ion level, and related method and use for reperfusion
BR112016023570A2 (pt) 2014-04-10 2017-08-15 Univ Health Network cânula para conexão de dispositivos médicos para sistemas biológicos
CA2945189C (en) 2014-04-10 2022-10-11 Quanser Consulting Inc. Robotic systems and methods of operating robotic systems
CA2943797A1 (en) 2014-04-10 2015-10-15 Christopher White Modulation of calcium ion homeostasis in harvested transplantable hearts
CN103893205B (zh) 2014-04-15 2016-03-09 青岛大学附属医院 一种包含利多卡因和腺苷的心脏停搏液及其制备方法
IL303658B2 (en) 2014-06-02 2024-07-01 Transmedics Inc Ex vivo organ care system
CA2970117A1 (en) 2014-12-12 2016-06-16 Darren FREED Apparatus and method for organ perfusion
US10124093B1 (en) 2015-01-16 2018-11-13 Kci Licensing, Inc. System and method for hybrid control of reduced pressures delivered to a tissue site
CN104770361B (zh) 2015-03-11 2017-05-17 浙江大学 肝移植术中供肝快速固定灌注装置
AU2016318622B2 (en) 2015-09-09 2021-05-20 Transmedics, Inc. Aortic cannula for ex vivo organ care system
ES2968062T3 (es) 2016-05-30 2024-05-07 Transmedics Inc Aparato y método de ventilación pulmonar ex vivo con presión exterior variable

Also Published As

Publication number Publication date
US11154050B2 (en) 2021-10-26
AU2020270499B2 (en) 2022-11-10
IL249277B (en) 2020-03-31
IL303658A (en) 2023-08-01
IL285965B2 (en) 2023-02-01
AU2019206070B2 (en) 2020-12-10
IL296525B1 (en) 2023-07-01
AU2015271799A1 (en) 2016-12-15
US11903381B2 (en) 2024-02-20
US11944088B2 (en) 2024-04-02
IL273266B (en) 2021-09-30
US20190021308A1 (en) 2019-01-24
EP3151663A1 (en) 2017-04-12
AU2015271799B2 (en) 2019-07-11
AU2023200688A1 (en) 2023-03-09
JP2022105036A (ja) 2022-07-12
EP3151663A4 (en) 2018-06-20
CN106659151B (zh) 2021-06-08
IL249277A0 (en) 2017-02-28
US20220232823A1 (en) 2022-07-28
JP2025028998A (ja) 2025-03-05
CA2950759A1 (en) 2015-12-10
JP7597756B2 (ja) 2024-12-10
IL310657B1 (en) 2025-11-01
IL310657A (en) 2024-04-01
IL303658B2 (en) 2024-07-01
IL303658B1 (en) 2024-03-01
US20240292831A1 (en) 2024-09-05
JP2020193219A (ja) 2020-12-03
IL285965A (en) 2021-10-31
ES2839202T3 (es) 2021-07-05
US10076112B2 (en) 2018-09-18
CN106659151A (zh) 2017-05-10
IL285965B (en) 2022-10-01
AU2019206070A1 (en) 2019-08-08
NZ726895A (en) 2021-10-29
WO2015187737A1 (en) 2015-12-10
EP3151663B1 (en) 2020-09-23
US20150342177A1 (en) 2015-12-03
IL296525A (en) 2022-11-01
IL296525B2 (en) 2023-11-01
US20220039373A1 (en) 2022-02-10
AU2020270499A1 (en) 2020-12-17
CN113287600B (zh) 2022-08-19
JP7530239B2 (ja) 2024-08-07
CA2950759C (en) 2023-02-21
IL273266A (en) 2020-04-30
JP2017518301A (ja) 2017-07-06
CA3185937A1 (en) 2015-12-10
CN113287600A (zh) 2021-08-24

Similar Documents

Publication Publication Date Title
IL310657B1 (en) Extracorporeal organ therapy system
EP3590403A4 (en) Endoscope
EP3344318A4 (en) Patient interfaces
DK3474804T3 (da) Medicinsk forbinding
DK3590543T3 (da) Medicinsk forbinding
EP3547968A4 (en) PROSTHESIS OBTAINED BY TISSUE ENGINEERING
DK3202305T3 (da) Engangsendoskop og system
DK3824731T3 (da) Aortakanyle til ex vivo-organplejesystem
EP3129952C0 (en) Tethered endoscope
EP3689221A4 (en) ENDOSCOPE
EP3528737A4 (en) MEDICAL SUPPORT
EP3689222A4 (en) ENDOSCOPE
BR112017018419A2 (pt) endoscópio flexível
DK3474803T3 (da) Medicinsk forbinding
PL3145592T3 (pl) Kompozycja do pielęgnacji skóry
DK3592297T3 (da) Vævsteknologistilladser
DK3122230T3 (da) Endoskopisk instrument
EP3656278A4 (en) ENDOSCOPE
EP3656276A4 (en) ENDOSCOPE
EP3656277A4 (en) ENDOSCOPE
FI20145982A7 (fi) Potilasalusta
EP3656281A4 (en) ENDOSCOPE
EP3609404A4 (en) MEDICAL SYSTEM
SE1651557A1 (sv) Medical support
FR3022783B1 (fr) Sebum artificiel