ATE218802T1 - Spüllösung für organe und gewebe - Google Patents
Spüllösung für organe und gewebeInfo
- Publication number
- ATE218802T1 ATE218802T1 AT94925823T AT94925823T ATE218802T1 AT E218802 T1 ATE218802 T1 AT E218802T1 AT 94925823 T AT94925823 T AT 94925823T AT 94925823 T AT94925823 T AT 94925823T AT E218802 T1 ATE218802 T1 AT E218802T1
- Authority
- AT
- Austria
- Prior art keywords
- solution
- organs
- tissues
- flushing solution
- liter
- Prior art date
Links
- 210000000056 organ Anatomy 0.000 title abstract 2
- 238000011010 flushing procedure Methods 0.000 title 1
- 239000000243 solution Substances 0.000 abstract 6
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 2
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 abstract 2
- 239000011591 potassium Substances 0.000 abstract 2
- 239000002126 C01EB10 - Adenosine Substances 0.000 abstract 1
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- JLVVSXFLKOJNIY-UHFFFAOYSA-N Magnesium ion Chemical compound [Mg+2] JLVVSXFLKOJNIY-UHFFFAOYSA-N 0.000 abstract 1
- 229960005305 adenosine Drugs 0.000 abstract 1
- 239000011575 calcium Substances 0.000 abstract 1
- 229910001424 calcium ion Inorganic materials 0.000 abstract 1
- 229910001425 magnesium ion Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 150000002772 monosaccharides Chemical class 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 229910001414 potassium ion Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910001415 sodium ion Inorganic materials 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
- 239000008215 water for injection Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10560293A | 1993-08-12 | 1993-08-12 | |
| PCT/US1994/009068 WO1995005076A1 (en) | 1993-08-12 | 1994-08-11 | Rinse solution for organs and tissues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE218802T1 true ATE218802T1 (de) | 2002-06-15 |
Family
ID=22306761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94925823T ATE218802T1 (de) | 1993-08-12 | 1994-08-11 | Spüllösung für organe und gewebe |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6080730A (de) |
| EP (1) | EP0713363B1 (de) |
| JP (1) | JPH09504513A (de) |
| AT (1) | ATE218802T1 (de) |
| AU (1) | AU7560994A (de) |
| CA (1) | CA2169272A1 (de) |
| DE (1) | DE69430805T2 (de) |
| WO (1) | WO1995005076A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5696152A (en) * | 1996-05-07 | 1997-12-09 | Wisconsin Alumni Research Foundation | Taxol composition for use as organ preservation and cardioplegic agents |
| US5834178C1 (en) * | 1997-07-09 | 2002-04-23 | Univ Wayne State | Flush-storage solution for donor organs |
| AU4501799A (en) * | 1998-05-29 | 1999-12-20 | Novartis Nutrition Ag | A new use for glycine |
| AUPQ077199A0 (en) * | 1999-06-03 | 1999-06-24 | Fremantle Heart Institute Pty Ltd | A method using potassium dihydrogen phosphate to reduce calcification of tissue |
| US7235649B2 (en) * | 2000-03-24 | 2007-06-26 | Duke University | Isolated GRP94 ligand binding domain polypeptide and nucleic acid encoding same, and screening methods employing same |
| GB0028414D0 (en) * | 2000-11-22 | 2001-01-03 | Univ Leeds | Flush preservation solution |
| WO2003029419A2 (en) * | 2001-10-01 | 2003-04-10 | Duke University | Three dimensional structure of crystalline grp94 binding domain, and its methods of use |
| DE10222561B4 (de) * | 2002-05-17 | 2009-12-10 | Dr. Franz Köhler Chemie GmbH | Protektive Lösung zur Verhinderung von Ischämieschäden |
| JP2006524260A (ja) * | 2003-04-23 | 2006-10-26 | ヒューマン バイオシステムズ | ドナー臓器の貯蔵用の改良された方法及び溶液 |
| EP1475434A1 (de) | 2003-05-09 | 2004-11-10 | Oncoscience AG | Verfahren zur Lagerung von Tumorzellen |
| EP1582213A1 (de) * | 2004-03-31 | 2005-10-05 | Ludwig-Maximilians-Universität München | Verwendung von Adenosine zur Behandlung von Chirurgie-verbundener Ischemia |
| US12010987B2 (en) | 2004-10-07 | 2024-06-18 | Transmedics, Inc. | Systems and methods for ex-vivo organ care and for using lactate as an indication of donor organ status |
| NZ591524A (en) | 2004-10-07 | 2012-09-28 | Transmedics Inc | Method for timing pulsatile flow of normothermic perfusate to the heart in ex-vivo organ care |
| WO2007014380A2 (en) | 2005-07-27 | 2007-02-01 | University Of North Carolina At Charlotte | Composition and method for the restoration and preservation of transplant organs procured from dcd donors |
| US9457179B2 (en) | 2007-03-20 | 2016-10-04 | Transmedics, Inc. | Systems for monitoring and applying electrical currents in an organ perfusion system |
| US8420380B2 (en) | 2008-01-31 | 2013-04-16 | Transmedics, Inc. | Systems and methods for ex vivo lung care |
| FR2974708B1 (fr) | 2011-05-02 | 2013-07-05 | Groupe Igl | Solution de rincage de greffon ou de tissu et procede de rincage dudit greffon ou tissu avant revascularisation |
| US10076112B2 (en) * | 2014-06-02 | 2018-09-18 | Transmedic, Inc. | Ex vivo organ care system |
| EP3347084B1 (de) | 2015-09-09 | 2020-11-11 | Transmedics, Inc. | Aortenkanüle für ex-vivo-organpflegesystem |
| CA3025673A1 (en) | 2016-05-30 | 2017-12-07 | Tevosol, Inc. | Apparatus and method for ex vivo lung ventilation with a varying exterior pressure |
| DE102017131059A1 (de) * | 2017-12-22 | 2019-06-27 | Christiane Kappert | Physiologisch verträgliche Lösung mit einem Gehalt an Pyruvat und Glycin, eine Pyruvat und Glycin enthaltende Zusammensetzung und Verfahren zu deren Herstellung |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5104859A (en) * | 1985-09-24 | 1992-04-14 | Solimedco Aktiebolag | Continuous administration of adenosine to reduce pulmonary vascular resistance |
| US5066578A (en) * | 1989-12-21 | 1991-11-19 | The Regents Of The University Of California | Long-term preservation of organs for transplantation |
| US5145771A (en) * | 1990-04-12 | 1992-09-08 | The University Of North Carolina At Chapel Hill | Rinse solution for organs and tissues |
| DE4133366A1 (de) * | 1991-10-09 | 1993-04-15 | Nycomed Arzneimittel Gmbh | Zusammensetzung zur verhinderung von schaeden in geweben durch sauerstoffunterversorgung |
-
1994
- 1994-08-11 AT AT94925823T patent/ATE218802T1/de not_active IP Right Cessation
- 1994-08-11 EP EP94925823A patent/EP0713363B1/de not_active Expired - Lifetime
- 1994-08-11 WO PCT/US1994/009068 patent/WO1995005076A1/en not_active Ceased
- 1994-08-11 DE DE69430805T patent/DE69430805T2/de not_active Expired - Fee Related
- 1994-08-11 CA CA002169272A patent/CA2169272A1/en not_active Abandoned
- 1994-08-11 JP JP7507067A patent/JPH09504513A/ja not_active Ceased
- 1994-08-11 AU AU75609/94A patent/AU7560994A/en not_active Abandoned
-
1995
- 1995-11-22 US US08/563,893 patent/US6080730A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0713363A4 (de) | 1998-06-10 |
| CA2169272A1 (en) | 1995-02-23 |
| DE69430805T2 (de) | 2003-02-13 |
| EP0713363A1 (de) | 1996-05-29 |
| DE69430805D1 (de) | 2002-07-18 |
| US6080730A (en) | 2000-06-27 |
| JPH09504513A (ja) | 1997-05-06 |
| AU7560994A (en) | 1995-03-14 |
| EP0713363B1 (de) | 2002-06-12 |
| WO1995005076A1 (en) | 1995-02-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |