DE69626976D1 - BEHANDLUNG EINER PROTEINLÖSUNG MIT A1/Fe UND ANSCHLIESENDE MEMBRANKONZENTRATION - Google Patents

BEHANDLUNG EINER PROTEINLÖSUNG MIT A1/Fe UND ANSCHLIESENDE MEMBRANKONZENTRATION

Info

Publication number
DE69626976D1
DE69626976D1 DE69626976T DE69626976T DE69626976D1 DE 69626976 D1 DE69626976 D1 DE 69626976D1 DE 69626976 T DE69626976 T DE 69626976T DE 69626976 T DE69626976 T DE 69626976T DE 69626976 D1 DE69626976 D1 DE 69626976D1
Authority
DE
Germany
Prior art keywords
protein solution
treatment
membrane concentration
following membrane
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69626976T
Other languages
English (en)
Other versions
DE69626976T2 (de
Inventor
Torben Kjaersgaard Nielsen
Mads Aage Laustsen
Niels-Viktor Nielsen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novozymes AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes AS filed Critical Novozymes AS
Application granted granted Critical
Publication of DE69626976D1 publication Critical patent/DE69626976D1/de
Publication of DE69626976T2 publication Critical patent/DE69626976T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69626976T 1995-06-02 1996-05-31 BEHANDLUNG EINER PROTEINLÖSUNG MIT A1/Fe UND ANSCHLIESENDE MEMBRANKONZENTRATION Expired - Lifetime DE69626976T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK62695 1995-06-02
DK62695 1995-06-02
PCT/DK1996/000229 WO1996038469A1 (en) 1995-06-02 1996-05-31 Al/Fe-TREATMENT OF A PROTEIN SOLUTION, FOLLOWED BY MEMBRANE CONCENTRATION

Publications (2)

Publication Number Publication Date
DE69626976D1 true DE69626976D1 (de) 2003-04-30
DE69626976T2 DE69626976T2 (de) 2004-03-04

Family

ID=8095720

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69626976T Expired - Lifetime DE69626976T2 (de) 1995-06-02 1996-05-31 BEHANDLUNG EINER PROTEINLÖSUNG MIT A1/Fe UND ANSCHLIESENDE MEMBRANKONZENTRATION

Country Status (9)

Country Link
EP (1) EP0828753B1 (de)
JP (1) JPH11511118A (de)
CN (1) CN1114613C (de)
AT (1) ATE235506T1 (de)
AU (1) AU5996996A (de)
DE (1) DE69626976T2 (de)
DK (1) DK0828753T3 (de)
IN (1) IN181859B (de)
WO (1) WO1996038469A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2810667B1 (fr) * 2000-06-23 2004-09-03 Warner Lambert Co Procede d'isolement et de purification d'une proteine, et proteine obtenue
CA3032990C (en) 2001-02-21 2020-07-14 Basf Enzymes Llc Enzymes having alpha amylase activity and methods of use thereof
US7659102B2 (en) 2001-02-21 2010-02-09 Verenium Corporation Amylases, nucleic acids encoding them and methods for making and using them
WO2002092802A1 (en) * 2001-05-14 2002-11-21 Diversa Corporation Novel methods of enzyme purification
EP1412384B1 (de) 2001-06-28 2007-12-26 Novo Nordisk A/S Stabile formulierung von modifiziertem glp-1
WO2003050274A2 (en) * 2001-12-11 2003-06-19 Novozymes A/S Process for harvesting crystalline particles from fermentation broth
US7118891B2 (en) 2001-12-11 2006-10-10 Novozymes A/S Crystal harvest from fermentation broth
CN101421400A (zh) 2003-03-06 2009-04-29 戴弗萨公司 淀粉酶、编码它们的核酸及其制备和应用方法
CN102940879B (zh) 2003-06-03 2017-06-06 诺沃挪第克公司 稳定化的药物肽组合物
WO2004105790A1 (en) 2003-06-03 2004-12-09 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
CN113304250A (zh) 2003-11-20 2021-08-27 诺和诺德股份有限公司 对于生产和用于注射装置中是最佳的含有丙二醇的肽制剂
US8710181B2 (en) 2004-08-31 2014-04-29 Novo Nordisk A/S Use of tris(hydroxymethyl) aminomethane for the stabilization of peptides, polypeptides and proteins
KR101340354B1 (ko) 2004-11-12 2013-12-11 노보 노르디스크 에이/에스 안정한 펩티드 제제
EP1934242B1 (de) 2005-09-15 2018-11-14 Wyeth LLC Proteinausflockung mit salzen
DK2479266T3 (en) 2006-12-21 2016-06-20 Basf Enzymes Llc Amylases and glucoamylases, nucleic acids encoding them, and methods of making and using the same
US20120252066A1 (en) * 2011-03-29 2012-10-04 Heng Meng H Methods of foam control
US20150291656A1 (en) 2012-11-01 2015-10-15 Novozymes A/S Method for removal of dna
CA2928805C (en) 2013-11-19 2022-03-29 Kemira Oyj Method for reducing colour of a biotechnological liquid
KR102665710B1 (ko) 2017-08-24 2024-05-14 노보 노르디스크 에이/에스 Glp-1 조성물 및 그 용도
CN108949703A (zh) * 2018-06-28 2018-12-07 大连理工大学 一种半纤维小体类似物粗提纯方法
CN113993878A (zh) 2019-06-13 2022-01-28 巴斯夫欧洲公司 用二价阳离子从发酵液中回收蛋白的方法
IL294521A (en) 2020-02-18 2022-09-01 Novo Nordisk As glp-1 compounds and their uses
US20230331775A1 (en) 2020-09-22 2023-10-19 Basf Se Method for recovering a protein from a fermentation broth comprising a high degree of lysed cells
CN112500471B (zh) * 2020-12-22 2022-09-27 中美华世通生物医药科技(武汉)股份有限公司 一种制备高澄清度蛋白琥珀酸铁的方法
WO2024028338A1 (en) 2022-08-02 2024-02-08 Basf Se Stabilized protein production process using bacillus host cells

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3795586A (en) * 1969-08-11 1974-03-05 Pabst Brewing Co Recovery of enzymes
IL85255A0 (en) * 1987-01-30 1988-07-31 Int Minerals & Chem Corp Recovery of somatotropin from dilute aqueous solutions
US4894444A (en) * 1987-07-16 1990-01-16 Merck & Co., Inc. Recovery and purification of immunogens from immunogen-alum complexes
DE3915277A1 (de) * 1989-05-10 1990-11-15 Henkel Kgaa Verfahren zur reinigung von enzymfluessigkonzentraten
DE4037530A1 (de) * 1990-11-26 1992-05-27 Henkel Kgaa Faellungsverfahren fuer exocellulaere proteine
DK91092D0 (de) * 1992-07-10 1992-07-10 Novo Nordisk As

Also Published As

Publication number Publication date
DE69626976T2 (de) 2004-03-04
ATE235506T1 (de) 2003-04-15
EP0828753A1 (de) 1998-03-18
JPH11511118A (ja) 1999-09-28
EP0828753B1 (de) 2003-03-26
IN181859B (de) 1998-10-03
DK0828753T3 (da) 2003-06-30
CN1114613C (zh) 2003-07-16
AU5996996A (en) 1996-12-18
CN1186498A (zh) 1998-07-01
WO1996038469A1 (en) 1996-12-05

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