JP5378685B2 - グラム陰性菌におけるｌｐｓの脱アシル化 - Google Patents
グラム陰性菌におけるｌｐｓの脱アシル化 Download PDFInfo
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04078445 | 2004-12-17 | ||
| EP04078445.6 | 2004-12-17 | ||
| PCT/NL2005/050081 WO2006065139A2 (en) | 2004-12-17 | 2005-12-16 | Deacylation of lps in gram negative bacteria |
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| Publication Number | Publication Date |
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| JP2008523805A JP2008523805A (ja) | 2008-07-10 |
| JP2008523805A5 JP2008523805A5 (enExample) | 2009-03-26 |
| JP5378685B2 true JP5378685B2 (ja) | 2013-12-25 |
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| JP2007546589A Expired - Fee Related JP5378685B2 (ja) | 2004-12-17 | 2005-12-16 | グラム陰性菌におけるｌｐｓの脱アシル化 |
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| US (1) | US8048433B2 (enExample) |
| EP (1) | EP1828378B1 (enExample) |
| JP (1) | JP5378685B2 (enExample) |
| CN (1) | CN101203605B (enExample) |
| AU (1) | AU2005317304B2 (enExample) |
| BR (1) | BRPI0519923A8 (enExample) |
| CA (1) | CA2590906C (enExample) |
| DK (1) | DK1828378T3 (enExample) |
| ES (1) | ES2493440T3 (enExample) |
| MX (1) | MX2007007288A (enExample) |
| NO (1) | NO340331B1 (enExample) |
| NZ (1) | NZ555889A (enExample) |
| PL (1) | PL1828378T3 (enExample) |
| PT (1) | PT1828378E (enExample) |
| WO (1) | WO2006065139A2 (enExample) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2393682T3 (es) | 2007-03-26 | 2012-12-27 | De Staat Der Nederlanden, Vert. Door De Minister Van Vws | Vacunas mejoradas contra Bordotella pertussis basadas en mutantes de glicosiltransferasa LPS |
| WO2014024026A1 (en) | 2012-08-06 | 2014-02-13 | Glaxosmithkline Biologicals S.A. | Method for eliciting in infants an immune response against rsv and b. pertussis |
| US20140037680A1 (en) | 2012-08-06 | 2014-02-06 | Glaxosmithkline Biologicals, S.A. | Novel method |
| ES2828373T3 (es) | 2013-06-04 | 2021-05-26 | Aparin Petr Gennadievich | Lipopolisacárido modificado (variantes) de bacterias endotóxicas, combinación de lipopolisacáridos modificados (variantes) y una vacuna (variantes), que los contiene, y una composición farmacéutica (variantes) |
| US11052142B2 (en) | 2013-06-04 | 2021-07-06 | Petr G. Aparin | Modified endotoxic bacteria lipopolysaccharide (variants), combination of modified lipopolysaccharides (variants) and, containing same, a vaccine (variants) and a pharmaceutical composition (variants) |
| EP3030260A1 (en) | 2013-08-05 | 2016-06-15 | GlaxoSmithKline Biologicals S.A. | Combination immunogenic compositions |
| US10420833B2 (en) | 2014-05-19 | 2019-09-24 | Board Of Regents, The University Of Texas System | Combinatorial platform for the display of surface adjuvants and antigens |
| CN104388368B (zh) * | 2014-10-30 | 2017-02-15 | 四川农业大学 | 一株低内毒素大肠杆菌原核表达工程菌突变株及构建方法 |
| CN109071586B (zh) * | 2016-01-28 | 2022-10-28 | 由卫生福利和体育大臣代表的荷兰王国 | 经修饰的四酰化奈瑟球菌lps |
| CN105567620B (zh) * | 2016-01-29 | 2019-03-19 | 江南大学 | 一株产减毒类脂A的Cronobacter sakazakii突变株及其应用 |
| CN105695540A (zh) * | 2016-03-18 | 2016-06-22 | 辽宁成大生物股份有限公司 | 一种革兰氏阴性菌胞壁抗原的制备方法 |
| EP3596110B1 (en) | 2017-03-13 | 2024-09-04 | Intravacc B.V. | Bordetella vaccines comprising lps with reduced reactogenicity |
| US11744884B2 (en) * | 2017-05-15 | 2023-09-05 | University Of Maryland, Baltimore | Live Salmonella typhi vectors engineered to express heterologous outer membrane protein antigens and methods of use thereof |
| AU2018379236B2 (en) * | 2017-12-04 | 2025-02-27 | Intravacc B.V. | An improved process for producing outer membrane vesicles |
| CN115552020A (zh) * | 2020-05-14 | 2022-12-30 | 默克专利股份公司 | 用于纯化腺相关病毒颗粒或腺病毒的方法和组合物 |
| CN116438193A (zh) | 2020-09-04 | 2023-07-14 | Intravacc有限责任公司 | OmpA突变增强百日咳博德特氏菌中OMV产生 |
| EP4169513A1 (en) | 2021-10-19 | 2023-04-26 | GlaxoSmithKline Biologicals S.A. | Adjuvant composition comprising sting agonists |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH650681A5 (en) * | 1981-08-14 | 1985-08-15 | Dso Pharmachim | Whooping cough vaccine |
| KR0168039B1 (ko) * | 1987-09-04 | 1999-01-15 | 로버트 디. 웨스트 | 재조합 dna에서 유도한 보르데텔라 외독소 소단위체의 유사체 및 그를 포함하는 백신 |
| EP0484621A3 (en) * | 1990-07-11 | 1992-08-26 | American Cyanamid Company | Efficacious vaccines against bordetella pertussis comprising a combination of individually purified pertussis antigens |
| HU219819B (hu) * | 1992-08-18 | 2001-08-28 | Dimminaco Ag/Sa/Ltd. | Izolált polinukleotidok, ezeket tartalmazó Bordetella bronchiseptica törzs, és Bordetella bronchiseptica elleni vakcina |
| NZ306391A (en) * | 1995-05-04 | 1999-03-29 | Connaught Lab | Acellular pertussis vaccines comprising purified toxin, filamentous haemagglutinin, pertactin and fimbrial agglutinogins |
| US6887483B2 (en) | 1995-12-01 | 2005-05-03 | University Of Iowa Research Foundation | Non-toxic mutants of pathogenic gram-negative bacteria |
| PL190237B1 (pl) * | 1997-04-01 | 2005-11-30 | Corixa Corp | Kompozycja adiuwantowa, szczepionka, sposób wytwarzania kompozycji adiuwantowej oraz zastosowanie |
| CA2264970A1 (en) | 1998-03-10 | 1999-09-10 | American Cyanamid Company | Antigenic conjugates of conserved lipolysaccharides of gram negative bacteria |
| JP3595264B2 (ja) * | 1998-11-03 | 2004-12-02 | デ・スタート・デル・ネーデルランデン・ベルテゲンボールディクト・ドール・デ・ミニステル・バン・ベルジーン・ボルクスゲツォントヘイト・エン・クルトゥール | 遺伝的に修飾されたグラム陰性細菌由来の低毒性ｌｐｓ |
| US6531131B1 (en) * | 1999-08-10 | 2003-03-11 | The United States Of America As Represented By The Department Of Health And Human Services | Conjugate vaccine for Neisseria meningitidis |
| WO2002085295A2 (en) * | 2001-04-20 | 2002-10-31 | The University Of Iowa Research Foundation | Methods and compositions for the modulation of biofilm formation |
-
2005
- 2005-12-16 ES ES05815467.5T patent/ES2493440T3/es not_active Expired - Lifetime
- 2005-12-16 MX MX2007007288A patent/MX2007007288A/es active IP Right Grant
- 2005-12-16 WO PCT/NL2005/050081 patent/WO2006065139A2/en not_active Ceased
- 2005-12-16 CA CA2590906A patent/CA2590906C/en not_active Expired - Fee Related
- 2005-12-16 DK DK05815467.5T patent/DK1828378T3/da active
- 2005-12-16 NZ NZ555889A patent/NZ555889A/en not_active IP Right Cessation
- 2005-12-16 BR BRPI0519923A patent/BRPI0519923A8/pt not_active Application Discontinuation
- 2005-12-16 US US11/722,034 patent/US8048433B2/en not_active Expired - Fee Related
- 2005-12-16 CN CN200580048420.6A patent/CN101203605B/zh not_active Expired - Fee Related
- 2005-12-16 AU AU2005317304A patent/AU2005317304B2/en not_active Ceased
- 2005-12-16 PT PT58154675T patent/PT1828378E/pt unknown
- 2005-12-16 EP EP05815467.5A patent/EP1828378B1/en not_active Expired - Lifetime
- 2005-12-16 JP JP2007546589A patent/JP5378685B2/ja not_active Expired - Fee Related
- 2005-12-16 PL PL05815467T patent/PL1828378T3/pl unknown
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2007
- 2007-06-18 NO NO20073088A patent/NO340331B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1828378E (pt) | 2014-10-10 |
| WO2006065139A2 (en) | 2006-06-22 |
| CN101203605A (zh) | 2008-06-18 |
| US8048433B2 (en) | 2011-11-01 |
| MX2007007288A (es) | 2008-02-25 |
| NO340331B1 (no) | 2017-04-03 |
| AU2005317304A1 (en) | 2006-06-22 |
| NO20073088L (no) | 2007-09-17 |
| CA2590906A1 (en) | 2006-06-22 |
| BRPI0519923A8 (pt) | 2018-01-23 |
| CA2590906C (en) | 2017-01-03 |
| WO2006065139A3 (en) | 2006-10-19 |
| NZ555889A (en) | 2009-07-31 |
| EP1828378A2 (en) | 2007-09-05 |
| PL1828378T3 (pl) | 2014-10-31 |
| US20080274145A1 (en) | 2008-11-06 |
| CN101203605B (zh) | 2016-01-27 |
| EP1828378B1 (en) | 2014-06-11 |
| ES2493440T3 (es) | 2014-09-11 |
| JP2008523805A (ja) | 2008-07-10 |
| BRPI0519923A2 (pt) | 2009-08-11 |
| DK1828378T3 (da) | 2014-09-01 |
| AU2005317304B2 (en) | 2011-06-23 |
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